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*  Regrelor
... is classified as an purinergic P2 receptor (P2Y12) antagonist. Other compounds in the same mechanistic class include ... It is characterized as a reversible, competitive receptor antagonist. The IC50 for antagonism of ADP-induced (P2Y12-mediated) ... ADP-receptor antagonist, INS50589". Platelets. 18 (5): 346-56. ,access-date= requires ,url= (help) "Regrelor Disodium". en. ... Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor ...
*  Multiple electrode aggregometry
"GPIIb/IIIa Antagonist Reagent". Haemoview Diagnostics. Retrieved 17 February 2016. Hechler, B; Gachet, C (1988). "P2 receptors ... and platelet function". Purinergic signalling. 27 (2011 September; 7(3)): 293-303. doi:10.1007/s11302-011-9247-6. PMID 3166986 ... Thrombin receptor activating peptide-6 (TRAP-6) activates platelets through the thrombin receptor protease activated receptor-1 ... The GPIIb/IIIa antagonist blocks the binding of fibrinogen to the GPIIb/IIIa receptors, preventing the formation of platelet- ...
*  Purinergic receptor
All of these are antiplatelet agents that block P2Y12 receptors. Data obtained from using P2 receptor-selective antagonists has ... P2 receptors) or adenosine (P1 receptors). P2 receptors have further been divided into five subclasses: P2X, P2Y, P2Z, P2U, and ... There are three known distinct classes of purinergic receptors, known as P1, P2X, and P2Y receptors. P2X receptors are ligand- ... IUPHAR GPCR Database - Adenosine receptors IUPHAR GPCR Database - P2Y receptors Purinergic Receptors at the US National Library ...
*  Rostral ventromedial medulla
GABAA receptor involvement was demonstrated by intrathecal administration of gabazine, a GABAA antagonist, in animals receiving ... Histological staining by another research group examined the distribution of purinergic receptor subtypes throughout the RVM. ... Activation of on cells by ATP was reversed by using the P2 antagonists suramin and pyridoxal-phosphate-6-azophenyl-2′,4′ ... Intra-RVM administration of AP5 or MK-801, NMDA receptor antagonists, resulted in a reversal of the mechanical sensitivity ...
*  Purinergic signalling
... was shown to block P2X3 receptor signaling Burnstock, Geoffrey (June 2006). "Purinergic P2 receptors as targets for novel ... receptor inhibitors. Before the expiry of its patent, the P2Y12 receptor antagonist Clopidogrel (trade name: Plavix) was the ... The purinergic signalling complex of a cell is sometimes referred to as the "purinome". Purinergic receptors, represented by ... Purinergic receptors are specific classes of membrane receptors that mediate various physiological functions such as the ...
*  Index of biochemistry articles
... purinergic P1 receptor - purinergic P2 receptor - purinergic receptor - pyridine - pyrimidine - pyruvate - pyruvate oxidation ... receptor (biochemistry) - receptor antagonist - receptor protein-tyrosine kinase - recombinant fusion protein - recombinant ... interleukin receptor - interleukin-1 receptor - interleukin-2 receptor - interleukin-3 - interleukin-3 receptor - intermediate ... G protein-coupled receptor - G3P - GABA - GABA receptor - GABA-A receptor - gag-onc fusion protein - galanin - gamete - gamma- ...
*  Adenosine receptor
The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ... Newer adenosine receptor agonists and antagonists are much more potent and subtype-selective, and have allowed extensive ... "Towards a revised nomenclature for P1 and P2 receptors". Trends Pharmacol. Sci. 18 (3): 79-82. doi:10.1016/S0165-6147(96)01038- ... Kalda A, Yu L, Oztas E, Chen JF (October 2006). "Novel neuroprotection by caffeine and adenosine A(2A) receptor antagonists in ...
*  PPADS
... (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) is a selective purinergic P2X antagonist. It is able to block ... Lambrecht, G. (1992). "PPADS, a novel functionally selective antagonist of P2 purinoreceptor mediated responses". European ... It appears to be relatively selective for P2X receptors, having no appreciable activity at α1 adrenergic, muscarinic M2 and M3 ... histamine H1, and adenosine A1 receptors. PPADS tetrasodium salt, Santa Cruz Biotechnology Ziganshin, AU (December 1993). " ...
*  P2RX7
One study in mice showed that blockade of P2X7 receptors attenuates onset of liver fibrosis. Purinergic receptor P2X receptor ... Gartland A, Buckley KA, Hipskind RA, Bowler WB, Gallagher JA (2003). "P2 receptors in bone--modulation of osteoclast formation ... 2009). "Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury ... The P2X7 subunits can form homomeric receptors only with a typical P2X receptor structure. The P2X7 receptor is a ligand-gated ...
*  P2RX1
... purinergic receptor P2X, ligand-gated ion channel, 1". North RA (2002). "Molecular physiology of P2X receptors". Physiol ... It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male ... 2004). "Increased mitogenic and decreased contractile P2 receptors in smooth muscle cells by shear stress in human vessels with ... "A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors". Br. J. ...