Many proteolipids are produced by the Bacillus subtilis family, and are composed of a cyclic structure made up of 7-10 amino ... Proteolipids are abundant in brain tissue, and are also present in many other animal and plant tissues. They include ghrelin, a ... A proteolipid is a protein covalently linked to lipid molecules, which can be fatty acids, isoprenoids or sterols. The process ... Myelin proteolipid protein This article incorporates text by Jessica Hutchinson available under the CC BY-SA 3.0 license. "MeSH ...
... (PLP or lipophilin) is the major myelin protein from the central nervous system (CNS). It plays an ... GPM6A; GPM6B; PLP1; PLP2 Dautigny A, Popot JL, Pham Dinh D (1991). "Major Myelin proteolipid: the 4-alpha-helix topology". J. ... Weimbs T, Sto ffel W (1992). "Proteolipid protein (PLP) of CNS myelin: positions of free, disulfide-bonded, and fatty acid ...
... (PLP1) is a form of myelin proteolipid protein (PLP). Mutations in PLP1 are associated with Pelizaeus- ... Edwards, A M; Ross N W; Ulmer J B; Braun P E (Jan 1989). "Interaction of myelin basic protein and proteolipid protein". J. ... Proteolipid protein 1 has been shown to interact with Myelin basic protein. PLP2 GRCh38: Ensembl release 89: ENSG00000123560 - ... 1986). "The gene encoding for the major brain proteolipid (PLP) maps on the q-22 band of the human X chromosome". Hum. Genet. ...
... myelin proteolipid] Thus, the two substrates of this enzyme are palmitoyl-CoA and myelin proteolipid, whereas its two products ... In enzymology, a [myelin-proteolipid] O-palmitoyltransferase (EC 2.3.1.100) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase. Other names in common ... Bizzozero OA, McGarry JF, Lees MB (1987). "Acylation of endogenous myelin proteolipid protein with different acyl-CoAs". J. ...
They are a type of proteolipids. The lipid groups play a role in protein interaction and can contribute to the function of the ...
Proteolipids, such as the Folch-Lees proteolipid identified by Lees, are critical constituents of cell membranes. They are ... She used antibodies raised against Folch-Lees proteolipid to study the membrane topology of Folch-Lees proteolipids. Alongside ... She was the first to identify the Folch-Lees proteolipid. She served as president of the American Society for Neurochemistry in ... The protein later became known as the Folch-Lees proteolipid. Lees started her independent academic career at the Geisel School ...
Some transmembrane proteolipids, especially those found in bacteria, are referred to as lipoproteins; they are not related to ... "Microbial Proteolipids and Lipopeptides - glycopeptidolipids, surfactin, iturnins, polymyxins, daptomycin". The LipidWeb. ...
"Biomimetic proteolipid vesicles for targeting inflamed tissues". Nature Materials. 15 (9): 1037-1046. Bibcode:2016NatMa.. ...
Greer JM, Lees MB (March 2002). "Myelin proteolipid protein--the first 50 years". The International Journal of Biochemistry & ... and proteolipid protein (PLP), which is the most abundant protein in CNS myelin, but only a minor component of PNS myelin. In ... "Perturbed interactions of mutant proteolipid protein/DM20 with cholesterol and lipid rafts in oligodendroglia: implications for ...
It is caused by mutations in proteolipid protein 1 (PLP1), a major myelin protein. It is characterized by a decrease in the ... Pelizaeus-Merzbacher disease is caused by X-linked recessive mutations in the major myelin protein proteolipid protein 1 (PLP1 ... "Therapeutic suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease in mice". bioRxiv: 508192. doi:10.1101/ ... "Suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease". Nature. 585 (7825): 397-403. Bibcode:2020Natur.585.. ...
"Therapeutic suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease in mice". bioRxiv: 508192. doi:10.1101/ ... "Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease". Nature. 585 (7825): 397-403. Bibcode:2020Natur.585.. ... "Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease". Nature. 585 (7825): 397-403. Bibcode:2020Natur.585.. ...
"Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease". Nature. 585 (7825): 397-403. Bibcode:2020Natur.585.. ...
Edwards AM, Ross NW, Ulmer JB, Braun PE (January 1989). "Interaction of myelin basic protein and proteolipid protein". Journal ... Edwards AM, Ross NW, Ulmer JB, Braun PE (January 1989). "Interaction of myelin basic protein and proteolipid protein". Journal ... Myelin basic protein has been shown to interact in vivo with proteolipid protein 1, and in vitro with calmodulin, actin, ...
January 1988). "cDNA, deduced polypeptide structure and chromosomal assignment of human pulmonary surfactant proteolipid, SPL( ... "Two SP-C genes encoding human pulmonary surfactant proteolipid". The Journal of Biological Chemistry. 263 (21): 10326-31. doi: ...
Proteolipid protein 2 is a protein that in humans is encoded by the PLP2 gene. GRCh38: Ensembl release 89: ENSG00000102007 - ... "Entrez Gene: PLP2 proteolipid protein 2 (colonic epithelium-enriched)". Breitwieser GE, McLenithan JC, Cortese JF, et al. (1997 ... "Colonic epithelium-enriched protein A4 is a proteolipid that exhibits ion channel characteristics". Am. J. Physiol. 272 (3 Pt 1 ...
Controlled by Ca2+, the membrane fusion of vesicles form water-filled pores from proteolipids. Pore forming cytolysins such as ... "Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion." Nature 409.6820 (2001): 581-588. ...
In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin ... Millán J, Puertollano R, Fan L, Rancaño C, Alonso MA (Jan 1997). "The MAL proteolipid is a component of the detergent-insoluble ... The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids ... Frank M, Schaeren-Wiemers N, Schneider R, Schwab ME (Aug 1999). "Developmental expression pattern of the myelin proteolipid MAL ...
Yoshida M, Shan WS, Colman DR (1999). "Conserved and divergent expression patterns of the proteolipid protein gene family in ... 2002). "Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes". Mol. Cell. Neurosci. 18 (6): 593-605. doi ...
This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of ... a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system". ...
Hodes ME, Blank CA, Pratt VM, Morales J, Napier J, Dlouhy SR (March 1997). "Nonsense mutation in exon 3 of the proteolipid ... April 2007). "Steroid-responsive neurologic relapses in a child with a proteolipid protein-1 mutation". Neurology. 68 (16): ... "X-linked spastic paraplegia and Pelizaeus-Merzbacher disease are allelic disorders at the proteolipid protein locus". Nature ...
Farrell LB, Nagley P (1987). "Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex". ...
Farrell LB, Nagley P (1987). "Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex". ...
Farrell LB, Nagley P (1987). "Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex". ... Gay NJ, Walker JE (1986). "Two genes encoding the bovine mitochondrial ATP synthase proteolipid specify precursors with ...
Farrell LB, Nagley P (May 1987). "Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex". ...
Hills, BA (1994). "Release of surfactant and a myelin proteolipid apoprotein in spinal tissue by decompression". Undersea & ...
"Proteolipids - proteins modified by covalent attachment to lipids - N-myristoylated, S-palmitoylated, prenylated proteins, ... DHHC domain Myristoylation Myelin proteolipid protein Palmitoleoylation Prenylation Dejanovic B, Semtner M, Ebert S, Lamkemeyer ...
... dicyclohexylcarbodiimide binding proteolipid of higher plant vacuolar H+-translocating ATPase". J. Biol. Chem. 262: 14745-14752 ...
Role of a Phospholipid-Proteolipid Complex". Calcified Tissue International. 81 (3): 191-205. doi:10.1007/s00223-007-9053-x. ...
His method led to the identification of myelin proteolipid (defined as a new type of lipoproteins) in white matter and water- ... Until the end of his career, the characterization of proteolipids was a major focus of Folch's work and interest. The Folch's ...
PMD is a rare monogenic disease caused by various mutations of the X-linked proteolipid protein 1 gene (PLP1). PLP1 is a ... In a myelinoid model of PMD caused by point mutations in Proteolipid protein 1 (PLP1), a CRISPR correction to the wildtype ... As the myelin organoid matures, the OPC cells differentiate into oligodendrocytes that express proteolipid protein 1 (PLP1), ... Certain classes of Pelizaeus-Merzbacher disease (PMD), Proteolipid protein 1 (PLP1) show perinuclear retention in ...