Cronan JE, Rock CO (1996). "Biosynthesis of membrane lipids". In Neidhardt, F.C. (ed.). Escherichia coli and Salmonella: ... acyl-carrier protein] dehydratase, 3-hydroxydecanoyl-acyl carrier protein dehydrase, 3-hydroxydecanoyl-acyl carrier protein ... acyl-carrier-protein] hydro-lyase) is an enzyme with systematic name (3R)-3-hydroxydecanoyl-(acyl-carrier protein) hydro-lyase ... acyl-carrier protein] ⇌ {\displaystyle \rightleftharpoons } a trans-dec-2-enoyl-[acyl-carrier protein] + H2O (2) a (3R)-3- ...
Lipids and Lipid Metabolism. 1394 (1): 3-15. doi:10.1016/S0005-2760(98)00091-5. PMID 9767077. Shanklin, J; Cahoon, E (1998). " ... Schultz, D; Suh, M.; Ohlrogge (2000). "Stearoyl-Acyl Carrier Protein and Unusual Acyl-Acyl Carrier Protein Desaturase ... acyl-carrier-protein] + acceptor + 2 H2O The systematic name of this enzyme class is acyl-[acyl-carrier-protein], hydrogen- ... acyl-carrier-protein), reduced acceptor, and O2, whereas its 3 products are oleoyl-(acyl-carrier-protein), acceptor, and H2O. ...
Lipids and Lipid Metabolism. 1302 (1): 1-16. doi:10.1016/0005-2760(96)00056-2. PMID 8695652. Chirala SS, Huang WY, Jayakumar A ... acyl carrier protein ⇌ CoA + malonyl-[acyl-carrier-protein] The transfer of malonate to acyl-carrier-protein (ACP) converts the ... Other names in common use include malonyl coenzyme A-acyl carrier protein transacylase, [acyl carrier protein] ... acyl carrier protein ⇌ CoA + malonyl-[acyl-carrier-protein] Thus, the two substrates of this enzyme are malonyl-CoA and acyl ...
"Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a". Journal of Lipid Research. ... Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass ... PMID 14563822.;chih长此人十二厂二 FOXO3A+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This ... Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME (February 2001). "Protein kinase SGK mediates survival signals by ...
"Sterol carrier protein-2". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1486 (1): 45-54. doi: ... The encoded protein catalyzes the last step of the mitochondrial fatty acid beta oxidation spiral. Unlike most mitochondrial ... The ACAA2 gene encodes a 41.9 kDa protein that is composed of 397 amino acids and contains 88 observed peptides. ... However, the ACAA2 locus has been associated with abnormal blood lipid levels, particularly HDL and LDL cholesterol levels; in ...
2006). "Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers". J. Lipid Res. 47 (1): 42-50 ... the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures". Proteins. 50 (2): ... Birkenmeier EH, Rowe LB, Crossman MW, Gordon JI (1995). "Ileal lipid-binding protein (Illbp) gene maps to mouse chromosome 11 ... Fatty acid binding protein 6, ileal (gastrotropin), also known as FABP6, is a protein which in humans is encoded by the FABP6 ...
They are composed of lipids and proteins that include various photosynthetic pigments and redox carriers. For this reason they ...
One known example of these transport proteins is the melibiose, or melB, carrier protein derived from the melB gene of E. coli ... Paoletti, Rodolfo; Kritchevsky, David (1966). Advances in Lipid Research, Volume 4. New York, NY: Academic Press Inc. pp. 218-9 ... cite book}}: ,website= ignored (help) "Melibiose Carrier Protein". UniProt. UniProt Consortium. Retrieved 21 May 2017. ... The protein is part of a system whose main function is to catalyze the accumulation and transport of lactose and other beta- ...
... exist bound to special carrier proteins in serum. Ceramide (Cer) can be generated by the breakdown of sphingomyelin (SM) by ... Sph is also known to interact with protein targets such as the protein kinase H homologue (PKH) and the yeast protein kinase ( ... Nishizuka, Y. (1995). "Protein kinase C and lipid signaling for sustained cellular responses". FASEB J. 9 (7): 484-496. doi: ... Lipid signaling, broadly defined, refers to any biological cell signaling event involving a lipid messenger that binds a ...
A notable example of the former is the farnesylation of small G-proteins including Ras, CDC42, Rho, and Rac. The attachment of ... Ubiquinone is a key electron carrier in the electron transport chain of cellular respiration. Isoprenoids are a large group of ... compounds that serve as biosynthetic precursors for lipids and hormones. Farnesyl and geranyl pyrophosphate also serve as ... Ericsson J, Jackson SM, Edwards PA (Oct 1996). "Synergistic binding of sterol regulatory element-binding protein and NF-Y to ...
Formation of lipid A precursors from UDP-GlcNAc in extracts of Escherichia coli". J. Biol. Chem. 260 (29): 15536-41. PMID ... 3-hydroxytetradecanoyl-acyl-carrier-protein and UDP-N-acetylglucosamine, whereas its two products are acyl-carrier-protein and ... acyl-carrier-protein] + UDP-N-acetylglucosamine ⇌ {\displaystyle \rightleftharpoons } [acyl-carrier-protein] + UDP-3-O-(3- ... In enzymology, an acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase (EC 2.3.1.129) is an enzyme that ...
Portal: Biology (Protein pages needing a picture, Articles with imported Creative Commons Attribution 4.0 text, Solute carrier ... Lysine Exporters are a superfamily of transmembrane proteins which export amino acids, lipids and heavy metal ions. They ... The superfamily was named based on the early discovery of the LysE carrier protein of Corynebacterium glutamicum. 2.A.75 - The ... These proteins are 190-240 amino acyl residues in length and possess six hydrophobic regions. PhoA fusion analyses of LysE of C ...
... gestrinone Steroid hormones are transported through the blood by being bound to carrier proteins-serum proteins that bind them ... These forms of hormones are lipids. They can pass through the cell membrane as they are fat-soluble, and then bind to steroid ... One possible pathway is that once inside the cell these complexes are taken to the lysosome, where the carrier protein is ... Steroid hormones are generally carried in the blood, bound to specific carrier proteins such as sex hormone-binding globulin or ...
Molecules suited for measurement by KinExA are antibodies, recombinant proteins, small molecules, aptamers, lipids, nanobodies ... "A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal ... 2012-03-14). Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives. Weinheim, Germany: Wiley-VCH Verlag GmbH & ... Leung, Elizabeth; Rohn, Troy; Fologea, Daniel (2018). "Quantifying Protein-DNA Interactions by Kinetics Exclusion Assay". ...
"Pathogenic mutations of the human mitochondrial citrate carrier SLC25A1 lead to impaired citrate export required for lipid, ... Tricarboxylate transport protein, mitochondrial, also known as tricarboxylate carrier protein and citrate transport protein ( ... SLC25A1 belongs to the mitochondrial carrier gene family SLC25. High levels of the tricarboxylate transport protein are found ... The structure of the tricarboxylate transport protein is consistent with the structures of other mitochondrial carriers. In ...
The carrier protein at the membrane binds to the glucose and alters its shape such that it can easily to be transported. ... such as retinol or lipids, are poorly soluble in water. They are transported through aqueous compartments of cells or through ... the transport relies on molecular binding between the cargo and the membrane-embedded channel or carrier protein. the rate of ... Larger molecules are transported by transmembrane carrier proteins, such as permeases, that change their conformation as the ...
This gene codes for a protein necessary for transporting lipids out of cells in the outermost layer of skin. The disorder is ... autosomal recessive and inherited from parents who are carriers. Diagnosis is often based on appearance at birth and confirmed ... ABCA12 is thought to be a lipid transporter in keratinocytes necessary for lipid transport into lamellar granules during the ... in the gene cause impaired transport of lipids in the skin layer and may also lead to shrunken versions of the proteins ...
Animal protein-free media, containing human serum albumin, human transferrin, but potentially animal-derived insulin and lipids ... carrier proteins, and attachment factors. These undefined animal-derived products will contain complex contaminants, such as ... Protein-free media (no protein but contains undefined peptides from plant hydrolysates) Chemically-defined media (with only ... Peptide-free, protein-free, chemically defined media are rarely successfully formulated except for CHO and insect cells. ...
Carrier ionophores may be proteins or other molecules. Channel formers that introduce a hydrophilic pore into the membrane, ... Many ionophores are lipid-soluble and transport ions across hydrophobic membranes, such as lipid bilayers found in the living ... Synthetic ion carriers have also been prepared. Ionophores selective for cations and anions have found many applications in ... Many ionophores are lipid-soluble entities that transport ions across the cell membrane. Ionophores catalyze ion transport ...
... "carrier state". The genome of Φ6 codes for 12 proteins. P1 is a major capsid protein which is responsible of forming the ... Lyytinen OL, Starkova D, Poranen MM (February 2019). "Microbial production of lipid-protein vesicles using enveloped ... The spike protein P3 is anchored to a fusogenic envelope protein in P6. P7 is a minor capsid protein, P8 is responsible of ... P12 is a non-structural morphogenic protein shown to be a part of the envelope assembly. P10 and P13 are proteins coding genes ...
Membranes for artificial cells can be made of simple polymers, crosslinked proteins, lipid membranes or polymer-lipid complexes ... Further, membranes can be engineered to present surface proteins such as albumin, antigens, Na/K-ATPase carriers, or pores such ... A biological red blood cell membrane including lipids and associated proteins can also be used to encapsulate nanoparticles and ... Nano sized oxygen carriers are used as a type of red blood cell substitutes, although they lack other components of red blood ...
The Ugo1 protein is a member of the MC superfamily. Mitochondrial fission Mitochondrial carriers MFN1 MFN2 OPA1 DNM1 ... At each membrane, these conserved proteins are required for the distinct steps of membrane tethering and lipid mixing. The ... Protein families, Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane ... These groups of proteins include mitofusins, OPA1/Mgm1, and Drp1/Dnm1. All of these molecules are GTP hydrolyzing proteins ( ...
... such as a protein. Antigens can be proteins, polysaccharides, lipids, nucleic acids or other biomolecules. This includes parts ... A hapten is a small molecule that can only induce an immune response when attached to a larger carrier molecule, ... Immunoglobulin-binding protein - Proteins such as protein A, protein G, and protein L that are capable of binding to antibodies ... Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of simple sugars), lipids, or nucleic acids. ...
"Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity ... peroxisome sterol carrier protein thiolase, sterol carrier protein, oxopristanoyl-CoA thiolase, peroxisomal 3-oxoacyl coenzyme ... Wanders RJ, Denis S, Wouters F, Wirtz KW, Seedorf U (1997). "Sterol carrier protein X (SCPx) is a peroxisomal branched-chain ...
... instruments are for instance part of the quality control process for mRNA vaccines formulated in lipid nanoparticle carriers. ... Particle size analyzers are used also in biology to measure protein aggregation. DLS is a particularly appreciated technique ...
The cause of the disease is a missense mutation on chromosome 8. The creation of a new protein occurs, and the lipid content of ... The ratio of the mutation carriers is 1:135. There is nothing that has been found to stop the progression of the disease, but ... This protein is a 286 amino acid transmembrane protein that has not been identified before, meaning that it is unique to ... These tests identify lipid content of the brain, and any anomaly from the norm may be linked to Northern epilepsy.[citation ...
... developed various polymeric nanoparticulate carrier systems. Lyophilization: lyophilized anticancer drugs and lipid/plasmid ... Formulation sciences: formulated various small drugs, proteins, oligonucleotides and plasmids for in vitro and in vivo studies ... Design of gene delivery systems: Developed polymer, lipid, lipopolymer and peptide-based systems to deliver and transfect ... Drug delivery and pharmacokinetics: determined the pharmacokinetic profiles of small molecules, proteins, oligonucleotides and ...
The acyl carrier protein of lipid synthesis donates lipoic acid to the pyruvate dehydrogenase complex in Escherichia coli and ... Lipoate-protein ligase (EC 2.7.7.63, LplA, lipoate protein ligase, lipoate-protein ligase A, LPL, LPL-B) is an enzyme with ... Lipoate---protein+ligase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: Biology (EC 2.7.7). ... Kim DJ, Kim KH, Lee HH, Lee SJ, Ha JY, Yoon HJ, Suh SW (November 2005). "Crystal structure of lipoate-protein ligase A bound ...
Lipid-soluble hormones must bond to carrier plasma glycoproteins (e.g., thyroxine-binding globulin (TBG)) to form ligand- ... An example of the usage of hormone-binding proteins is in the thyroxine-binding protein which carries up to 80% of all ... and the majority of these belong to the G protein-coupled receptor (GPCR) class of seven alpha helix transmembrane proteins. ... Lipid soluble hormones, (such as steroids) generally pass through the plasma membranes of target cells (both cytoplasmic and ...
Seedorf U, Ellinghaus P, Roch Nofer J (2000). "Sterol carrier protein-2". Biochim. Biophys. Acta. 1486 (1): 45-54. doi:10.1016/ ... Lipid Res. 33 (11): 1597-605. doi:10.1016/S0022-2275(20)41382-3. PMID 1464743. Watkins PA, McGuinness MC, Raymond GV, et al. ( ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation ...