Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, ... Cytoplasmic polyadenylation element-binding protein 1 is a protein that in humans is encoded by the CPEB1 gene. This gene ... This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. ... Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants ...

An independent assessment using the Xenopus oocyte system reported in 2016 that while PfATP6 protein could be detected, ... 124 separate Pf proteins and >60 proteins that bound to this molecule were identified. This work was substantiated in 2022 ... The protein is thought to be a P-type ATPase involved in calcium ion transport. Mutations in PfATP6 that had been identified in ... CS1: long volume value, Orphaned articles from August 2016, All orphaned articles, Protein pages needing a picture, Genes). ...

Whereas most 7-transmembrane proteins are G protein-coupled receptors that open other ion channels indirectly via second ... Both sequences were found to function as single-component light-activated cation channels in a Xenopus oocytes and human kidney ... In terms of structure, channelrhodopsins are retinylidene proteins. They are seven-transmembrane proteins like rhodopsin, and ... This change introduces a further one in the transmembrane protein, opening the pore to at least 6 Å. Within milliseconds, the ...

... +protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) WikiGenes TBX22 TBX22 human gene ... have demonstrated that several T-box genes are involved in mesoderm specification in the developing embryo of mouse or Xenopus ... The Brachyury protein binds as a dimer to a 20-nucleotide partially palindromic sequence recognized by its T-domain. More ... T-box transcription factor TBX22 is a protein that in humans is encoded by the TBX22 gene. TBX22 is a member of a ...

... synaptic vesicle proteins, and channel proteins. A deficiency in the proper development of these proteins can cause the neural ... In Xenopus laevis, RE1/NRSE and REST/NRSF dysfunction or mutation demonstrated significant impact on neural tube, cranial ... stretch in the protein. The mutated Htt protein affects an individual's proper neural functions by inhibiting the action of ... which includes the TATA-binding protein (TBP) that binds to the TATA box along with 13 other proteins that bind to TBP. The ...

... an Arg protein tyrosine kinase binding protein that is the human homologue of a CNS-specific Xenopus gene". Oncogene. 12 (9): ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene. ABI2 has ... Cao C, Leng Y, Li C, Kufe D (2003). "Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative ...

The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is ... specific localization in human brain and their influence on CaV2.1 voltage-dependent calcium channels expressed in Xenopus ... CACNG4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CACNG4 genome location and ... Voltage-dependent calcium channel gamma-4 subunit is a protein that in humans is encoded by the CACNG4 gene. L-type calcium ...

It is, however, thought to play a role as a scaffolding protein in a G-coupled protein receptor complex in Xenopus tropicalis. ... TMEM69, also known as Transmembrane protein 69, is a protein that in humans is encoded by the TMEM69 gene. A notable feature of ... This complex is part of a G-coupled protein receptor which acts as the receptor for a binding ligand, kisspeptin in the plasma ... Conserved domains found within TMEM69 are part of DUF3429, which is a family of uncharacterized proteins found in bacteria and ...

The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is ... specific localization in human brain and their influence on CaV2.1 voltage-dependent calcium channels expressed in Xenopus ... This protein is similar to the mouse stargazin protein, mutations in which having been associated with absence seizures, also ... "Stargazin and other transmembrane AMPA receptor regulating proteins interact with synaptic scaffolding protein MAGI-2 in brain ...

This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive ... Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene. ...

... is a protein that in humans is encoded by the NCAPG gene. CAP-G is a subunit of condensin I, a large protein complex involved ... Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts". J. ... triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library". Cancer Res. 60 ( ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ...

Each of these proteins have unique neural markers. Overexpression of either SOX1, SOX2, or SOX 3 increases neural progenitors ... Nitta KR, Takahashi S, Haramoto Y, Fukuda M, Onuma Y, Asashima M (December 2006). "Expression of Sox1 during Xenopus early ... In non-mammalian vertebrates, loss of one SOXB1 protein results in minor phenotypic differences. This supports the claim that ... Guth SI, Wegner M (October 2008). "Having it both ways: Sox protein function between conservation and innovation". Cell. Mol. ...

The protein is predicted to be in the nuclear region of the cell. Three nuclear signals include HKKK at 129(pat 4), KKK at 130( ... The most distantly related ortholog is Xenopus tropicalis, the Western Clawed Frog. Based on the years of divergence for ... FAM227A is a protein that in humans is encoded by FAM227A gene. Current studies have determined the location of this gene to be ... This protein is not predicted to be ubiquitous as the rate of expression varies across tissue types. Currently, the function of ...

This protein adjustment can induce a subtle shift in the range of smells an animal can sense. The diversity of smelling genes ... In Xenopus laevis, an amphibia, both class receptors are present, unlike fish or mammals. Their class I receptors are expressed ... These proteins contain seven transmembrane domains that are responsible for detecting specific sets of odor molecules. OR genes ... Freitag, J., Krieger, J., Strotmann, J., & Breer, H. (1995). "Two classes of olfactory receptors in Xenopus laevis". Neuron, 15 ...

Example includes both single proteins such as RNase III, RNase A, RNase T1, RNase T2 and RNase H and also complexes of proteins ... Further examples include endoribonuclease XendoU found in frogs (Xenopus). Endoribonucleases at the U.S. National Library of ...

Protein - NCBI". "WD repeat-containing protein 75 [Xenopus laevis] - Protein - NCBI". "PREDICTED: WD repeat-containing protein ... "WD repeat-containing protein 75 [Bos taurus] - Protein - NCBI". "WD repeat-containing protein 75 [Mus musculus] - Protein - ... Protein - NCBI". "WD repeat-containing protein 75 [Rattus norvegicus] - Protein - NCBI". "WD repeat-containing protein 75 [ ... See also: List of proteins in the human body)WDR75 is a human protein encoded by the WDR75 gene containing a WD40 superfamily ...

... is classified as a ZIC protein due to conservation of the five C2H2 zinc fingers, which enables the protein to interact ... Experiments in Xenopus also support the idea that Zic5 can regulate formation of neural crest, suggesting this function is ... ZIC5 is a member of the Zinc finger of the cerebellum (ZIC) protein family. ZIC5 is located on chromosome 13 in a divergently ... Similar to other ZIC family members, ZIC5 is also able to interact with TCF proteins in order to inhibit canonical Wnt ...

"Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome ... ssTnI is not expressed in the embryonic hearts of Xenopus and zebrafish, while it is expressed in the somites and skeletal ... Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. It is a tissue-specific subtype of ... As homologous proteins, ssTnI, fast skeletal muscle TnI and cardiac TnI have highly conserved structures and crystallographic ...

Slimb is a component of the Skp1/Cullin/F-box protein (SCF) ubiquitin ligase complex, which marks proteins for proteosomal ... Xenopus casein kinase 1 gamma (CK1gamma) is associated with the cell membrane and binds to LRP. CK1gamma was found to be needed ... Since then, double-time's protein product DBT has been well characterized for its role in phosphorylating PER, the protein ... Hanks SK, Hunter T (May 1995). "Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain ...

He correctly predicted the central role of F-Box in protein degradation due to the large number of proteins having this motif. ... is a homolog of Xenopus Eg1". EMBO Journal. 10 (9): 2653-2659. doi:10.1002/j.1460-2075.1991.tb07808.x. PMC 452966. PMID 1714386 ... Elledge's group also discovered the F-box protein structural motif, and found that it recognizes specific protein sequences and ... "The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit" (PDF). Genes & Development. 7 (9 ...

The PAX genes give instructions for making proteins that attach themselves to certain areas of DNA. This nuclear protein is ... Xenopus tropicalis". Xenbase. xenbase.org. Retrieved 2009-07-17. A Xenopus laevis and tropicalis resource This article ... These mutations can affect different functions of the protein including DNA binding, gene activation, protein stability, and ... Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. This gene is a member of the ...

In Xenopus retinotectal projection systems, the expression of these proteins has been shown to be influenced by guidance cues ... For instance, in Xenopus retinotectal connection systems, the pioneer axons of retinal ganglion cells originate from the dorsal ... CAMs are the major class of proteins mediating correct axonal navigation of axons growing on axons (fasciculation). There are ... As a result, studies suggest that local protein expression is a convenient mechanism to explain the rapid, dynamic, and ...

2002). "Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ... Ribosome biogenesis protein BRX1 homolog (BRIX1) also known as brix domain-containing protein 2 (BXDC2) is a protein that in ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ...

The N-terminal region mediates binding of Hs-BUB1 to the mitotic kinetochore protein blinkin (a protein also commonly referred ... Studies in Xenopus extracts using RNAi or antibody depletion have indicated a crucial function of Bub1 in the organization of ... Bub1 is a serine/threonine protein kinase first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound ... The protein kinase Bub1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome ...

The fusome may be the degradation site for other cell cycle proteins. Myt1 kinase inhibits CycA/Cdk1 in males during G2. ... 2004). Formation, architecture and polarity of female germline cyst in Xenopus. Dev Biol 266: 43-61. doi:10.1016/j.ydbio. ... In females, the connections are the channels through which nurse cells send proteins and RNAs to the oocyte along polarized ... Cytoskeleton components, such as alpha and beta spectrins, hu-li tai shao (hts), and ankyrin were the first proteins identified ...

Sato N, Arai K, Masai H (Sep 1997). "Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro ... The protein is expressed at constant levels throughout the cell cycle. The gene coding for the Dbf4 or ASK protein is regulated ... Because the two proteins, Cdc7 and Dbf4, must form a complex before activating the MCM complex, the regulation of one protein ... The protein is a serine-threonine kinase that is activated by another protein called either Dbf4 in the yeast Saccharomyces ...

Another protein Commissureless (Comm) was found to be an essential regulator of Robo: in comm mutants, Robo activity is too ... Robo binds directly to the cytoplasmic domain of DCC and experiments with Xenopus explants have shown that this interaction ... Brose K, Bland KS, Wang KH, Arnott D, Henzel W, Goodman CS, Tessier-Lavigne M, Kidd T (March 1999). "Slit proteins bind Robo ... Slit refers to a secreted protein that is most widely known as a repulsive axon guidance cue, and Robo refers to its ...

The Cl−-formate exchanger, otherwise known as Pendrin encoded by the SLC26A4 gene, is a transport protein present in the kidney ... Da, Scott; Lp, Karniski (January 2000). "Human Pendrin Expressed in Xenopus Laevis Oocytes Mediates Chloride/Formate Exchange ...

Transmembrane Protein 269 (TMEM269) is a protein which in humans is encoded by the TMEM269 gene. The gene is located on the ... The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary ... Sci Rep 8, 14678 (2018). https://doi.org/10.1038/s41598-018-33045-2 "Protein BLAST: search protein databases using a protein ... April 2021). "Protein N-myristoylation: functions and mechanisms in control of innate immunity". Cellular & Molecular ...

Protein kinase C alpha (PKCα) is an enzyme that in humans is encoded by the PRKCA gene. Protein kinase C (PKC) is a family of ... PKC-α has been widely studied in the tissues of many organisms including drosophila, xenopus, cow, dog, chicken, human, monkey ... Protein kinase C-alpha (PKC-α) is a specific member of the protein kinase family. These enzymes are characterized by their ... RACK and other proteins can regulate the expression of all PKC family proteins. In this particular study, however, only PKC ...

This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is translational ... In mice, MSI2 has been found to be in 11qB5-C and BC169841 in the African clawed frog (Xenopus laevis). There are two different ... Musashi-2, also known as Musashi RNA binding protein 2, is a protein that in humans is encoded by the MSI2 gene. Like its ... As with the rest of Musashi family RNA-binding proteins, MSI2 is linked to tissue stem cells and has an influence in asymmetric ...

Human proteins, Protein structure, Membrane proteins, Protein families, Articles containing video clips). ... "Voltage sensitive phosphoinositide phosphatases of Xenopus: their tissue distribution and voltage dependence". Journal of ... VSPs are made up of two protein domains: a voltage sensor domain, and a phosphatase domain coupled to a lipid-binding C2 domain ... The search was designed to identify proteins which contained a sequence of amino acids called a voltage sensor, because this ...