*PTPRZ1

... tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein phosphatase ... "Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases ... Receptor-type tyrosine-protein phosphatase zeta also known as phosphacan is an enzyme that in humans is encoded by the PTPRZ1 ... "Entrez Gene: PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1". Krueger NX, Saito H (1992). "A human ...

*PCSK5

"Increased proteolytic processing of protein tyrosine phosphatase mu in confluent vascular endothelial cells: the role of PC5, a ... The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are ... This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought ... Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (2001). "Systematic subcellular localization of novel proteins ...

*Protein primary structure

Such reactions are catalyzed by kinases and the reverse reaction is catalyzed by phosphatases. The phosphorylated tyrosines are ... Protein primary structure is the linear sequence of amino acids in a peptide or protein. By convention, the primary structure ... The protein is activated by cleaving off the inhibitory peptide. Some proteins even have the power to cleave themselves. ... Similar to phosphorylated tyrosines, sulfated tyrosines are used for specific recognition, e.g., in chemokine receptors on the ...

*Protein tyrosine phosphatase

"The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1". Protein Sci. 15 (6): 1500- ... Tyrosine-specific protein phosphatases (PTPase; EC 3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine ... Protein tyrosine phosphatases are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on ... LMW (low-molecular-weight) phosphatases, or acid phosphatases, act on tyrosine phosphorylated proteins, low-MW aryl phosphates ...

*Para-Nitrophenylphosphate

Lorenz, Ulrike (2017-05-07). "Protein Tyrosine Phosphatase Assays". Current protocols in immunology / edited by John E. Coligan ... This property can be used to determine the activity of various phosphatases including alkaline phosphatase (AP) and protein ... tyrosine phosphatase (PTP). The substance is sensitive to light, and thus should be stored protected from light. This is also ... Phosphatases catalyze the hydrolysis of pNPP liberating inorganic phosphate and the conjugate base of para-nitrophenol (pNP). ...

*PTPRF

Receptor-type tyrosine-protein phosphatase F is an enzyme that in humans is encoded by the PTPRF gene. The protein encoded by ... "Insulin receptor protein-tyrosine phosphatases. Leukocyte common antigen-related phosphatase rapidly deactivates the insulin ... "The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions". ... "The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions". ...

*MTMR14

"Protein tyrosine phosphatases in the human genome". Cell. 117 (6): 699-711. doi:10.1016/j.cell.2004.05.018. PMID 15186772. ... Myotubularin related protein 14 also known as MTMR14 is a protein which in humans is encoded by the MTMR14 gene. Expression of ... MTMR14 is a phosphatidylinositol-3-phosphatase that dephosphorylates the same substrates as myotubularin, PtdIns(3)P and PtdIns ... 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287- ...

*FAN1

"Protein tyrosine phosphatases in the human genome". Cell. 117 (6): 699-711. doi:10.1016/j.cell.2004.05.018. PMID 15186772. ... The FA proteins play an elaborate role with FAN1 to remove these ICLs. The pathway consists of 15 known proteins. Three of them ... It is a structure dependent endonuclease and a member of the myotubularin-related class 1 cysteine-based protein tyrosine ... This is present in proteins that bind to ubiquitinated proteins, and is highly conserved across eukaryotes. This Zinc finger is ...

*Kohzoh Imai

Imai discovered three kinds of protein tyrosine phosphatase (PTP) genes having the function of controlling the signal ... "Mammalian SH2-containing protein tyrosine phosphatase". Cell. 85: 15. doi:10.1016/s0092-8674(00)81077-6. http://www.nikkei.com/ ... similarity in genomic organization within protein-tyrosine phosphatasegenes". Oncogene. 9: 3031-3035. PMID 8084610. Adachi M, ...

*PTPRM

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases ... "Receptor protein tyrosine phosphatases, cell adhesion and signal transduction". Advances in Protein Phosphatases. 8: 241-71. ... "Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine ... Rosdahl JA, Mourton TL, Brady-Kalnay SM (2002). "Protein kinase C delta (PKCdelta) is required for protein tyrosine phosphatase ...

*RNA triphosphatase

Barford, D; Flint, A J; Tonks, N K (11 March 1994). "Crystal structure of human protein tyrosine phosphatase 1B". Science. 263 ... These enzymes are very much similar to protein tyrosine phosphatases in their structure and mechanism. This family includes ... Denu, John M; Dixon, Jack E (January 1998). "Protein tyrosine phosphatases: mechanisms of catalysis and regulation". Current ... "Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism". Proceedings of the National Academy of ...

*DUSP10

Martell KJ, Angelotti T, Ullrich A (1998). "The "VH1-like" dual-specificity protein tyrosine phosphatases". Mol. Cells. 8 (1): ... Dual specificity protein phosphatase 10 is an enzyme that in humans is encoded by the DUSP10 gene. Dual specificity protein ... Tanoue, T; Yamamoto T; Maeda R; Nishida E (Jul 2001). "A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 ... Tanoue T, Yamamoto T, Maeda R, Nishida E (2001). "A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha ...

*Trodusquemine

Cho, H (2013). "Protein tyrosine phosphatase 1B (PTP1B) and obesity". Vitamins and hormones. 91: 405-24. doi:10.1016/B978-0-12- ...

*PTPMT1

Protein tyrosine phosphatase, mitochondrial 1 is a protein that in humans is encoded by the PTPMT1 gene. GRCh38: Ensembl ... Protein tyrosine phosphatase, mitochondrial 1". Retrieved 2017-01-12. Niemi NM, Lanning NJ, Westrate LM, MacKeigan JP (2013). " ... "Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death". PLoS ONE. 8 (1): e53803. ...

*PTPN22

"Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic ... Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by ... The proteins are located in the cytoplasm.[citation needed] This gene encodes a protein tyrosine phosphatase which is expressed ... requirements for association of protein-tyrosine phosphatase PEP with the Src homology 3 domain of inhibitory tyrosine protein ...

*NEDD9

Liu F, Hill DE, Chernoff J (1996). "Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src ... a novel mechanism of protein tyrosine phosphatase substrate recognition". Oncogene. 15 (8): 877-85. doi:10.1038/sj.onc.1201279 ... "Fyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in ... novel SH2-containing protein family), and other proteins such as the Id family of helix-loop-helix proteins. In terms of post- ...

*Helicobacter pylori

CagA then allosterically activates protein tyrosine phosphatase/protooncogene Shp2. Pathogenic strains of H. pylori have been ... Once inside the cell, the CagA protein is phosphorylated on tyrosine residues by a host cell membrane-associated tyrosine ... The other four families are porins, iron transporters, flagellum-associated proteins, and proteins of unknown function. Like ... independent of protein tyrosine phosphorylation. A great deal of diversity exists between strains of H. pylori, and the strain ...

*Nicholas Kester Tonks

"Protein tyrosine phosphatases: from genes, to function, to disease". Nature Reviews Molecular Cell Biology. 7: 833-846. doi: ... His research is mainly focused on studying the function and regulation of protein tyrosine phosphatases. He did his ... After graduation, he joined Sir Philip Cohen lab in University of Dundee for his PhD study in protein phosphatase from 1982- ... "MRC Protein Phosphorylation Unit :: Research :: Philip Cohen :: Profiles for Past Lab Members". Ppu.mrc.ac.uk. Retrieved 2016- ...

*IQGAP1

Phillips-Mason PJ, Gates TJ, Major DL, Sacks DB, Brady-Kalnay SM (2006). "The receptor protein-tyrosine phosphatase PTPmu ... or poly-proline protein-protein domain, so named because of two functionally conserved tryptophans, W, is a protein-protein ... IQGAP1 is a 190 kDa protein with 5 domains. A protein domain is a subsection of a protein that shows up multiple times in ... "IQGAP1: Gene and protein summary". The Human Protein Atlas. Retrieved 2011-05-31. Stradal T, Kranewitter W, Winder SJ, Gimona M ...

*Stem cell marker

Maduro MR, Davis E, Davis A, Lamb DJ (May 2002). "Osteotesticular protein tyrosine phosphatase expression in rodent testis". ... Below is a list of genes/protein products that can be used to identify various types of stem cells, or functional assays that ... Stahl J, Wobus AM, Ihrig S, Lutsch G, Bielka H (September 1992). "The small heat shock protein hsp25 is accumulated in P19 ... Stem cell markers are genes and their protein products used by scientists to isolate and identify stem cells. Stem cells can ...

*Trypsin 1

Gu M, Majerus PW (1996). "The properties of the protein tyrosine phosphatase PTPMEG". J. Biol. Chem. 271 (44): 27751-9. doi: ... Trypsin-1, also known as cationic trypsinogen, is a protein that in humans is encoded by the PRSS1 gene. Trypsin-1 is the main ... Identification of pancreas-specific protein as pancreatic procarboxypeptidase B". J. Biol. Chem. 267 (4): 2575-81. PMID 1370825 ...

*PTPN4

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling ... and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1". ... Tyrosine-protein phosphatase non-receptor type 4 is an enzyme that in humans is encoded by the PTPN4 gene. ... "Entrez Gene: PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)". Hironaka K, Umemori H, Tezuka T, Mishina ...

*DUSP1

It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family ... dual-specificity protein tyrosine phosphatases". Molecules and Cells. 8 (1): 2-11. PMID 9571625. Keyse SM (Apr 1998). "Protein ... "Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase". Nature. 359 (6396): 644-7. doi: ... "The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase". Proceedings of the National ...

*PTPN7

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling ... Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. ... "Entrez Gene: PTPN7 protein tyrosine phosphatase, non-receptor type 7". Pettiford SM, Herbst R (February 2000). "The MAP-kinase ... Adachi M, Sekiya M, Arimura Y, Takekawa M, Itoh F, Hinoda Y, Imai K, Yachi A (1992). "Protein-tyrosine phosphatase expression ...

*PTP4A2

Protein tyrosine phosphatase type IVA 2 is an enzyme that in humans is encoded by the PTP4A2 gene. The protein encoded by this ... "Entrez Gene: PTP4A2 protein tyrosine phosphatase type IVA, member 2". Rommens JM, Durocher F, McArthur J, et al. (1996). " ... Zeng Q, Hong W, Tan YH (Apr 1998). "Mouse PRL-2 and PRL-3, two potentially prenylated protein tyrosine phosphatases homologous ... 2006). "Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer". Br. J ...

*Prokaryotic DNA replication

... which contains multiple binding sites for the initiator protein DnaA (a highly homologous protein amongst bacterial kingdom). ... This pocket has a tyrosine residue that is able to form van der Waals interactions with the correctly paired nucleotide. In ... by inorganic phosphatase) into two phosphates. This hydrolysis drives DNA synthesis to completion. Furthermore, DNA polymerase ... In E. coli these proteins include DiaA, SeqA, IciA, HU, and ArcA-P, but they vary across other bacterial species. A few other ...

*DUSP5

Kwak SP, Dixon JE (Jan 1995). "Multiple dual specificity protein tyrosine phosphatases are expressed and regulated ... The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases ... "Chromosomal localization of four human VH1-like protein-tyrosine phosphatases". Genomics. 22 (2): 462-4. doi:10.1006/geno. ... a dual specificity MAP kinase protein phosphatase". Proteins. 66 (1): 253-8. doi:10.1002/prot.21224. PMID 17078075. Sarközi R, ...