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*  PTPRZ1
... receptor tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein ... Receptor-type tyrosine-protein phosphatase zeta also known as phosphacan is an enzyme that in humans is encoded by the PTPRZ1 ... "Entrez Gene: PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1". Krueger NX, Saito H (1992). "A human ... "Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases ...
*  PTPN11
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), SHP-2, or ... PTPN11 is a protein tyrosine phosphatase (PTP) Shp2. PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs ... "Entrez Gene: PTPN11 protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)". Sobreira NL, Cirulli ET, ... "Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction". J. Biol. ...
*  Noonan syndrome with multiple lentigines
... multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene (PTPN11). The disease ... 2006). "Reduced phosphatase activity of SHP-2 in LEOPARD syndrome: consequences for PI3K binding on Gab1". FEBS Lett. 580 (10 ... It was believed as late as 2002 that Noonan Syndrome with Multiple Lentigines (NSML) was related to neurofibromatosis type I ( ... the mutations cause a loss of catalytic activity of the SHP2 protein (the gene product of the PTPN11 gene), which is a ...
*  Protein tyrosine phosphatase
... into 38 classical PTPs 21 receptor tyrosine phosphatase 17 nonreceptor-type PTPs 61 VH-1-like or dual-specific phosphatases ( ... "The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1". Protein Sci. 15 (6): 1500- ... "The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila". ... Yang CH, Huang CC, Hsu KS (May 2012). "A critical role for protein tyrosine phosphatase nonreceptor type 5 in determining ...
*  Epidermal growth factor receptor
Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function". Molecular and Cellular ... Tiganis T (January 2002). "Protein tyrosine phosphatases: dephosphorylating the epidermal growth factor receptor". IUBMB Life. ... mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor ... "Association of SH2 domain protein tyrosine phosphatases with the epidermal growth factor receptor in human tumor cells. ...
*  PTPRK
"Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function". J Biol Chem. 280 (52): ... The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Protein tyrosine phosphatases ... Receptor-type tyrosine-protein phosphatase kappa is an enzyme that in humans is encoded by the PTPRK gene. PTPRK is also known ... "Entrez Gene: PTPRK protein tyrosine phosphatase, receptor type, K". Missing or empty ,url= (help) Zhang Y, Siebert R, ...
*  PTPRCAP
Protein tyrosine phosphatase receptor type C-associated protein is an enzyme that in humans is encoded by the PTPRCAP gene. The ... PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein". Schraven B, Schoenhaut D, Bruyns E, et al. (1994 ... 2000). "CD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transduction". Eur. J. ... 2001). "A novel function for the Tec family tyrosine kinase Itk in activation of β1 integrins by the T-cell receptor". EMBO J. ...
*  PTPRO
2007). "Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor ... Receptor-type tyrosine-protein phosphatase O is an enzyme that in humans is encoded by the PTPRO gene. This gene encodes a ... "Entrez Gene: PTPRO protein tyrosine phosphatase, receptor type, O". Seimiya H, Sawabe T, Inazawa J, Tsuruo T (1995). "Cloning, ... 2004). "Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human ...
*  PTPRG
Receptor-type tyrosine-protein phosphatase gamma is an enzyme that in humans is encoded by the PTPRG gene. The protein encoded ... "Entrez Gene: PTPRG protein tyrosine phosphatase, receptor type, G". Kaplan R, Morse B, Huebner K, et al. (1990). "Cloning of ... three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in ... Jul 1991). "Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21". ...
*  PTPRF
Receptor-type tyrosine-protein phosphatase F is an enzyme that in humans is encoded by the PTPRF gene. The protein encoded by ... "Entrez Gene: PTPRF protein tyrosine phosphatase, receptor type, F". Bonvini P, An WG, Rosolen A, Nguyen P, Trepel J, Garcia de ... "Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR". Mol ... "Insulin receptor protein-tyrosine phosphatases. Leukocyte common antigen-related phosphatase rapidly deactivates the insulin ...
*  PTPRN2
Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) also known as islet cell autoantigen-related protein (ICAAR) and ... "Entrez Gene: PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2". Caromile LA, Oganesian A, Coats SA, Seifert ... Lan MS, Lu J, Goto Y, Notkins AL (1994). "Molecular cloning and identification of a receptor-type protein tyrosine phosphatase ... 1999). "Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in ...
*  CCDC180
"PTPN12 protein tyrosine phosphatase, non-receptor type 12 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. ... "SRC - Proto-oncogene tyrosine-protein kinase Src - Homo sapiens (Human) - SRC gene & protein". www.uniprot.org. Retrieved 2016- ... Ccaat-enhancer binding protein KRAB domain zinc finger protein 57 Krüppel-like C2H2 zinc finger factors Octamer binding protein ... Coiled-coil domain containing protein 180 (CCDC180) is a protein that in humans is encoded by the CCDC180 gene. This protein is ...
*  PTPN6
Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), ... "Entrez Gene: PTPN6 protein tyrosine phosphatase, non-receptor type 6". Amin S, Kumar A, Nilchi L, Wright K, Kozlowski M (August ... "Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphatase". J. Biol. ... The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling ...
*  PTPRU
Receptor-type tyrosine-protein phosphatase PCP-2 (also known as PTP-pi, PTP lambda, hPTP-J, PTPRO and PTP psi), is an enzyme ... "Entrez Gene: PTPRU protein tyrosine phosphatase, receptor type, U". Crossland S, Smith PD, Crompton MR (1996). "Molecular ... "Characterization of the adhesive properties of the type IIb subfamily receptor protein tyrosine phosphatases". Cell Commun ... "Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase ...
*  PTPN7
Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene. The protein encoded ... "Entrez Gene: PTPN7 protein tyrosine phosphatase, non-receptor type 7". Pettiford SM, Herbst R (February 2000). "The MAP-kinase ... receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase ... protein-tyrosine phosphatase, nonreceptor-type 11) mutations in seven Japanese patients with Noonan syndrome". J. Clin. ...
*  Chromosome 12 (human)
... encoding protein Parathymosin PTPN11: protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) PUS1: encoding ... achondrogenesis type 2 collagenopathy, types II and XI cornea plana 2 episodic ataxia hereditary hemorrhagic telangiectasia ... cblB type MON2: encoding protein Protein MON2 homolog MUCL1: encoding protein Mucin-like protein 1 MYO1A: myosin IA NANOG: NK-2 ... encoding protein Zinc finger C3H1-type containing ZNF26: encoding protein Zinc finger protein 26 ZNF84: encoding protein Zinc ...
*  PTPN9
Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene. The protein encoded ... PTPN9 protein tyrosine phosphatase, non-receptor type 9". Kruger JM, Fukushima T, Cherepanov V, et al. (2002). "Protein- ... 2004). "Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor". Mol ... 2007). "Association of protein-tyrosine phosphatase MEG2 via its Sec14p homology domain with vesicle-trafficking proteins". J. ...
*  IRS2
"Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR". Mol ... 1996). "The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2". J. Biol. Chem. 271 ( ... Algenstaedt P, Antonetti DA, Yaffe MB, Kahn CR (1997). "Insulin receptor substrate proteins create a link between the tyrosine ... Insulin receptor substrate 2 is a protein that in humans is encoded by the IRS2 gene. This gene encodes the insulin receptor ...
*  KCNA2
"Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of ... This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed ... "Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of ... "Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin". The Journal of ...
*  Actinin alpha 1
"Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT)". Brain Res. 1116 (1): 50- ... Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal ... Actinin, alpha 1 has been shown to interact with: CDK5R1, CDK5R2, Collagen, type XVII, alpha 1, GIPC1, PDLIM1, Protein kinase ... Bunn RC, Jensen MA, Reed BC (1999). "Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a ...
*  PTPRH
Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene. The protein encoded by ... "Entrez Gene: PTPRH protein tyrosine phosphatase, receptor type, H". Noguchi T, Tsuda M, Takeda H, et al. (2001). "Inhibition of ... 2004). "Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor". Mol ... 2001). "Gene for the human transmembrane-type protein tyrosine phosphatase H (PTPRH): genomic structure, fine-mapping and its ...
*  PTPN21
Tyrosine-protein phosphatase non-receptor type 21 is an enzyme that in humans is encoded by the PTPN21 gene. The protein ... "Entrez Gene: PTPN21 protein tyrosine phosphatase, non-receptor type 21". Jui HY, Tseng RJ, Wen X, Fang HI, Huang LM, Chen KY, ... Jui HY, Tseng RJ, Wen X, Fang HI, Huang LM, Chen KY, Kung HJ, Ann DK, Shih HM (2001). "Protein-tyrosine phosphatase D1, a ... "Expression of protein tyrosine phosphatase PTP-RL10 and its isoform in the mouse testis". Int. J. Urol. 6 (11): 572-7. doi: ...
*  PTPN23
Tyrosine-protein phosphatase non-receptor type 23 is an enzyme that in humans is encoded by the PTPN23 gene. GRCh38: Ensembl ... "Entrez Gene: PTPN23 protein tyrosine phosphatase, non-receptor type 23". Nakajima D, Okazaki N, Yamakawa H, et al. (2003). " ... A novel protein tyrosine phosphatase gene on human chromosome 3p21.3". Biochem Biophys Res Commun. 278 (3): 671-8. doi:10.1006/ ... Mariotti M, Castiglioni S, Maier JA (2006). "Expression analysis and modulation by HIV-Tat of the tyrosine phosphatase HD-PTP ...
*  PTPRS
Receptor-type tyrosine-protein phosphatase S, also known as R-PTP-S, R-PTP-sigma, or PTPσ, is an enzyme that in humans is ... "Entrez Gene: PTPRS protein tyrosine phosphatase, receptor type, S". Lang BT, Cregg JM, DePaul MA, Tran AP, Xu K, Dyck SM, ... "Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3". Genomics. 38 (1): 76 ... Lajus S, Lang J (2006). "Splice variant 3, but not 2 of receptor protein-tyrosine phosphatase sigma can mediate stimulation of ...
*  PTPRM
Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene. The protein encoded by ... Protein tyrosine phosphatases are protein enzymes that remove phosphate moieties from tyrosine residues on other proteins. ... "Entrez Gene: PTPRM protein tyrosine phosphatase, receptor type, M". Tonks NK, Yang Q, Flint AJ, Gebbink MF, Franza BR, Hill DE ... "Receptor protein tyrosine phosphatases, cell adhesion and signal transduction". Advances in Protein Phosphatases. 8: 241-71. ...
*  ABL (gene)
"Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl ... "Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop ... "A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle". ... Cao C, Leng Y, Li C, Kufe D (April 2003). "Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the ...