Both recognize and bind poly-A RNA to transport RNA. Most SR proteins that do not shuttle out of the nucleus with an RNA ... SR proteins are a conserved family of proteins involved in RNA splicing. SR proteins are named because they contain a protein ... SR proteins can be either shuttling SR proteins or nonshuttling SR proteins. Some SR proteins associate with RNA export factor ... RS domains regulate protein-protein interactions of SR proteins. Based on sequence analysis, SR proteins are suspected to be ...

Plasma retinol-binding protein, the retinol transport vehicle in serum. CRBP I/II, cellular-binding proteins involved in ... Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. ... MacDonald PN, Bok D, Ong DE (June 1990). "Localization of cellular retinol-binding protein and retinol-binding protein in cells ... Harney JP, Smith LC, Simmen RC, Fliss AE, Bazer FW (May 1994). "Retinol-binding protein: immunolocalization of protein and ...

... zinc transport and zinc-independent proteins". The Journal of Biological Chemistry. 284 (27): 18377-89. doi:10.1074/jbc. ... Articles with short description, Short description matches Wikidata, Protein domains, Bacterial proteins). ... In molecular biology, ZinT (formerly known as YodA) is a family of protein domains found in prokaryotes. The domain contains a ... Petrarca, P; Ammendola, S; Pasquali, P; Battistoni, A (March 2010). "The Zur-regulated ZinT protein is an auxiliary component ...

Zinc transporter proteins (Zrt), or simply zinc transporters, are membrane transport proteins of the solute carrier family ... Unlike some other zinc transporter proteins, the mechanism of how Zn2+ is transported via ZntB is not well understood. However ... v t e (Protein pages needing a picture, Solute carrier family, All stub articles, Membrane protein stubs). ... have been able to speculate that the transport of Zn2+ is related to pH gradient and the electrostatics of the protein membrane ...

MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the ... These channel proteins function in transporting water, small carbohydrates (e.g., glycerol), urea, NH3, CO2, H2O2 and ions by ... Some members of the family, including the yeast Fps1 protein (TC# 1.A.8.5.1) and tobacco NtTIPa (TC# 1.A.8.10.2) may transport ... a glycerol uptake/efflux facilitator protein. Drosophila neurogenic protein 'big brain' (bib). This protein may mediate ...

Protein families, Membrane proteins, Transmembrane proteins, Transmembrane transporters, Transport proteins, Integral membrane ... The generalized transport reaction catalyzed by NRAMP family proteins is: Me2+ (out) + H+ (out) ⇌ Me2+ (in) + H+ (in). All ... Humans and rodents possess two distinct Nramp proteins. The broad specificity NRAMP2 (DMT1) transports a range of divalent ... Both proteins also mediate H+-dependent Fe2+ uptake. These proteins are of 575 and 549 amino acyl residues in length and are ...

"Golgi cisternal unstacking stimulates COPI vesicle budding and protein transport". PLOS ONE. 3 (2): e1647. Bibcode:2008PLoSO... ... Golgi reassembly-stacking protein 1 (GORASP1) also known as Golgi reassembly-stacking protein of 65 kDa (GRASP65) is a protein ... The GORASP1 protein is a peripheral membrane protein anchored to the lipid bilayer through myristoylation of a glycine residue ... GORASP1 can form a complex with the Golgi matrix protein GM130, and this complex binds to the vesicle docking protein p115. ...

This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and ... Major vault protein is a protein that in humans is encoded by the MVP gene. 78 copies of the protein assemble into the large ... This gene encodes the major vault protein which is a lung infection resistance-related protein. Vaults are multi-subunit ... "The drug resistance-related protein LRP is the human major vault protein". Nature Medicine. 1 (6): 578-82. doi:10.1038/nm0695- ...

This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several ... Solute carrier family 26 member 6 is a protein that in humans is encoded by the SLC26A6 gene. It is an anion-exchanger ... "SLC26A6 Gene - GeneCards , S26A6 Protein , S26A6 Antibody". www.genecards.org. Retrieved 2021-05-06. Markovich D (2001). " ... This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. ...

... be transported to the plasma membrane for secretion and it allows the Wnt protein to bind its receptor Frizzled Wnt proteins ... Dsh proteins are present in all organisms and they all share the following highly conserved protein domains: an amino-terminal ... For example, Wnt proteins are palmitoylated. The protein porcupine mediates this process, which means that it helps regulate ... This destruction complex includes the following proteins: Axin, adenomatosis polyposis coli (APC), protein phosphatase 2A (PP2A ...

Many different cargo proteins can be transported into the nucleus by importin. Often, different proteins will require different ... Protein pages needing a picture, Genes on human chromosome 3, Genes on human chromosome 17, Protein families, Transport ... but the key proteins involved had not been elucidated up until that point. A 60 kDa cytosolic protein, essential for protein ... Importin is a type of karyopherin that transports protein molecules from the cell's cytoplasm to the nucleus. It does so by ...

Mitochondrial electron transport chain mutations that extend the life span of Caenorhabditis elegans (nematode worms) also ... upregulating protein folding chaperones, and degrading excess misfolded proteins via ER associated protein degradation (ERAD). ... Just as proteins must be folded to function in the cytosol, proteins in organelles like the endoplasmic reticulum (ER) and ... When unfolded proteins build up, it dissociates to from the membrane to aid in protein folding. GRP78 dissociation triggers the ...

ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct ... This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates ... 2001). "Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion ... "Transport of HIV protease inhibitors through the blood-brain barrier and interactions with the efflux proteins, P-glycoprotein ...

"Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the ... The oxysterol-binding protein (OSBP)-related proteins (ORPs) are a family of lipid transfer proteins (LTPs). Concretely, they ... It is thought that it takes part in protein-protein interactions, but it is not known for certain. In some proteins, it also ... Universal protein resource accession number Q96SU4 for "Oxysterol-binding protein-related protein 9 - Homo sapiens (Human)" at ...

... (AE2) is a membrane transport protein that in humans is encoded by the SLC4A2 gene. AE2 is ... Gehrig H, Müller W, Appelhans H (April 1992). "Complete nucleotide sequence of band 3 related anion transport protein AE2 from ... Finally, the AE2 protein returns to its inward-facing conformation and releases Cl- into the cytosol. This working cycle of the ... The cryo electron microsopic studies revealed that human AE2 protein forms a homodimer and stays in resting state of inward- ...

In this manner, they can facilitate the transport of proteins, vesicles and organelles along the apical-basal axis of the cell ... MAP-1 proteins consists of a set of three different proteins: A, B and C. The C protein plays an important role in the ... including the motor proteins dynein and kinesin, microtubule-severing proteins like katanin, and other proteins important for ... Hirokawa N, Noda Y, Tanaka Y, Niwa S (October 2009). "Kinesin superfamily motor proteins and intracellular transport". Nature ...

Understanding how protein folding occurs in three-dimensional molecules is one of biology's enduring problems. Proteins with ... Shvartsburg, Alexandre A. (2008). Differential Ion Mobility Spectrometry: Nonlinear Ion Transport and Fundamentals of FAIMS. ... studying protein folding and protein conformation in the gas phase, using techniques such as Ion-mobility spectrometry. In 1995 ... examining the role of proteins and protein folding in neurodegenerative diseases, identifying possible cancer-related markers ...

The encoded protein is a transmembrane protein located in the mitochondrial inner membrane and catalyzes the transport of ... The encoded protein (PHC) catalyzes the transport of phosphate from the cytosol into the mitochondrial matrix, either by proton ... The encoded protein (PHC) is a multi-pass transmembrane protein located in the mitochondrial inner membrane; it contains six ... Phosphate carrier protein, mitochondrial is a protein that in humans is encoded by the SLC25A3 gene. ...

Friedberg I (September 1977). "The effect of ionophores on phosphate and arsenate transport in Micrococcus lysodeikticus". FEBS ... Cerberus inhibits the proteins bone morphogenetic protein 4 (BMP4), Xnr1, and Xwnt8. This gene encodes a cytokine member of the ... Cerberus is a protein that in humans is encoded by the CER1 gene. Cerberus is a signaling molecule which contributes to the ... The proteins that Cerberus inhibits (BMP4, Xnr1, Xwnt8) concentrations were increased also. It was also shown that just the ...

Kanai M, Raz A, Goodman DS (September 1968). "Retinol-binding protein: the transport protein for vitamin A in human plasma". ... Retinol binding protein 4, also known as RBP4, is a transporter protein for retinol (vitamin A alcohol). RBP4 has a molecular ... Naylor HM, Newcomer ME (March 1999). "The structure of human retinol-binding protein (RBP) with its carrier protein ... This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A) in the blood. It delivers ...

Roggenkamp A, Ackermann N, Jacobi CA, Truelzsch K, Hoffmann H, Heesemann J (2003). "Molecular analysis of transport and ... Portal: Biology (Protein domains, Protein families, Virulence factors, Bacterial proteins). ... In molecular biology, YadA is a protein domain which is short for Yersinia adhesin A. These proteins have strong sequence and ... YadA is a homotrimeric outer membrane protein which forms part of the fibrillar matrix. Simplistically, this means the protein ...

Kunji, E.R.S.; King, M.S.; Ruprecht, J.J.; Thangaratnarajah, C. (2020). "The SLC25 Carrier Family: Important Transport Proteins ... An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter. An ... The two proteins thus work in parallel with one generating heat and the other generating ATP from ADP and inorganic phosphate, ... Uncoupling proteins play a role in normal physiology, as in cold exposure or hibernation, because the energy is used to ...

Pro-sequences may also be involved in pro-protein transport and secretion. Pro-domain (or prodomain) is the domain of a ... A protein precursor, also called a pro-protein or pro-peptide, is an inactive protein (or peptide) that can be turned into an ... Like other proteins that contain a signal peptide, their name is prefixed by pre. They are thus called pre-pro-proteins or pre- ... Protein precursors are often used by an organism when the subsequent protein is potentially harmful, but needs to be available ...

The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although ... 2000). "Anion transport in heart". Physiol. Rev. 80 (1): 31-81. doi:10.1152/physrev.2000.80.1.31. PMID 10617765. S2CID 15954128 ... Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease. Chloride channel ... CLCA1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CLCA1 genome location and ...

These proteins are primarily concerned with cholesterol transport StAR (STARD1) MLN64 (STARD3) These proteins are involved in ... Protein pages needing a picture, Peripheral membrane proteins, Protein domains, Water-soluble transporters). ... STARD7 STARD10 Collagen type IV alpha-3-binding protein (COL4A3BP/Ceramide transfer protein (CERT)/STARD11) These proteins ... The archetypical domain is found in StAR (Steroidogenic acute regulatory protein), a mitochondrial protein that is synthesized ...

... proteins. The destination is chosen accordingly. Unfortunately, details about the intermediate transporting steps are unknown. ... the PDZ domain is a common structural motif in proteins that help mediate protein-protein interactions. The AMPA receptor amino ... Glutamate receptor-interacting protein (GRIP) refers to either a family of proteins that bind to the glutamate receptor or ... Proteins in the glutamate receptor-interacting protein (GRIP) family have been shown to interact with GluR2, a common subunit ...

Cargo proteins containing a nuclear localization signal (NLS) are bound by importins and transported into the nucleus. Inside ... Ran (RAs-related Nuclear protein) also known as GTP-binding nuclear protein Ran is a protein that in humans is encoded by the ... Ran is a small 25 kDa protein that is involved in transport into and out of the cell nucleus during interphase and also ... Cytoplasmic RanGDP is imported into the nucleus by the small protein NUTF2 (Nuclear Transport Factor 2), where RCC1 can then ...

Commercial Protein Crystal Growth experiment; Chemical Vapor Transport Experiment Heat Pipe Performance Experiment (CVTEHPPE); ...

This protein is voltage-sensitive. Contrary to previous research, prestin has also been shown to transport anions; the exact ... Therefore, a change in the shape of many prestin proteins, which tend to conglomerate together, will ultimately lead to a ... Bai, J. P.; Surguchev, A.; Montoya, S.; Aronson, P. S.; Santos-Sacchi, J.; Navaratnam, D. (2009). "Prestin's Anion Transport ... Prestin is the transmembrane protein underlying the OHC's ability to elongate and contract, a process essential for OHC ...

However, large proteins must have a specific signaling sequence to be transported across the outer membrane, so the protein ... Glucose-related protein 75 (grp75) is another dual-function protein. In addition to the matrix pool of grp75, a portion serves ... Larger proteins can enter the mitochondrion if a signaling sequence at their N-terminus binds to a large multisubunit protein ... Herrmann JM, Neupert W (April 2000). "Protein transport into mitochondria" (PDF). Current Opinion in Microbiology. 3 (2): 210- ...

α-FetoProtein (AFP) is part of the α1 globulin family of proteins. Alpha globulins are round transport proteins that have a ... Fetal proteins are high levels of proteins present during the fetal stage of development. Often related proteins assume similar ... This protein resembles albumin and is the main protein found in fetal serum. Human AFP is coded by a gene on chromosome 4, is ... The protein has a different structure than the adult protein because of this and helps in fetal development. Fetal hemoglobin ...

In either prokaryotes or mitochondria they are localized to the outer membrane, and have been shown to bind and transport ... Tryptophan-rich sensory proteins (TspO) are a family of proteins that are involved in transmembrane signalling. ... This article incorporates text from the public domain Pfam and InterPro: IPR004307 (Protein pages needing a picture, Protein ... TspO works through (or modulates) the PpsR/AppA system and acts upstream of the site of action of these regulatory proteins. It ...

Fujii R, Takumi T (December 2005). "TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines ... FUS/TLS is a member of the FET protein family that also includes the EWS protein, the TATA-binding protein TBP-associated ... "FUS - RNA-binding protein FUS - Homo sapiens (Human) - FUS gene & protein". www.uniprot.org. Retrieved 2019-03-13. Kino Y, ... Wada K, Inoue K, Hagiwara M (August 2002). "Identification of methylated proteins by protein arginine N-methyltransferase 1, ...

"Localization of bicoid mRNA in late oocytes is maintained by continual active transport". Developmental Cell. 11 (2): 251-262. ... Homeotic protein bicoid is encoded by the bcd maternal effect gene in Drosophilia. Homeotic protein bicoid concentration ... that is similar to the one found in the HIV protein REV and is essential for its nucleic acid binding. Bicoid protein gradient ... Bicoid protein represses the translation of caudal mRNA and enhances the transcription of anterior gap genes including ...

Ca2+ Chemistry, Storage and Transport in Biologic Systems: An Overview. Madame Curie Bioscience Database [Internet]. Retrieved ... Calcium-binding proteins are proteins that participate in calcium cell signaling pathways by binding to Ca2+, the calcium ion ... Calcium binding proteins also serve an important physiological role for cells. The most ubiquitous Ca2+-sensing protein, found ... S100B proteins are abundantly found in cancerous tumor cells causing them to be overexpressed, therefore making these proteins ...

Most evidence suggest that the Hrd1 E3 ubiquitin-protein ligase can function as a retrotranslocon or dislocon to transport ... The Vpu protein of HIV-1 is a protein on the ER membrane and targets newly made CD4 in the endoplasmic reticulum for ... However, HIV produces the membrane protein Vpu that binds to CD4. The Vpu protein mainly retains the CD4 in the ER by SCFβ-TrCP ... Not only membrane proteins surviving the first checkpoint are controlled for their luminal domains, also soluble proteins are ...

The term is used in other areas of biology to refer more broadly to non-protein (or even protein) molecules that either ... "Esterification of inorganic phosphate coupled to electron transport between dihydrodiphosphopyridine nucleotide and oxygen". J ... and FAD-dependent proteins". Proteins. 44 (3): 282-91. doi:10.1002/prot.1093. PMID 11455601. S2CID 10848692. Bryce (March 1979 ... whereas molecules that inhibit receptor proteins are termed corepressors. One such example is the G protein-coupled receptor ...

"RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor". Nature. 393 (6683): 333-9. ... Receptor activity-modifying proteins (RAMPs) are a class of protein that interact with and modulate the activities of several ... Single-pass transmembrane proteins, All stub articles, Protein stubs). ... Receptor+activity+modifying+protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles ...