Loading...
*  Protein quaternary structure
... protein-protein interaction when discussing quaternary structure of proteins and consider all assemblies of proteins as protein ... "Predicting protein quaternary structure by pseudo amino acid composition". Proteins: Structure, Function, and Bioinformatics. ... Protein quaternary structure can be determined using a variety of experimental techniques that require a sample of protein in a ... Protein quaternary structure is the number and arrangement of multiple folded protein subunits in a multi-subunit complex. It ...
*  Pentameric protein
A pentameric protein is a quaternary protein structure that consists of five protein subunits. Five sub-units come together to ... Hucho, F.; Changeux, J.-P. (1973). "Molecular weight and quaternary structure of the cholinergic receptor protein extracted by ... Protein enclosing bacterial organelles carboxysome is also made up of pentameric protein. Synthetic pentameric proteins include ... Many viral capsids are formed by hexameric and pentameric proteins. Such capsids are assigned a triangulation number (T-number ...
*  Apoptosome
The apoptosome is a large quaternary protein structure formed in the process of apoptosis. Its formation is triggered by the ... "Structure of the Drosophila Apoptosome at 6.9 Å Resolution." Structure. 2011 January;19(1):128-140. S. Qi; Y. Pang; Q. Hu; Q. ... "Structure of an apoptosome-procaspase-9 CARD complex." Structure. 2010 May;18(5):571-83. Acehan, D; Jiang, X; Morgan, DG; ... WD-40 repeats are sequences around 40 amino acids long which end in Trp-Asp and are typically involved in protein-protein ...
*  Tetrameric protein
A tetrameric protein is a protein with a quaternary structure of four subunits (tetrameric). Homotetramers have four identical ... For homotetrameric proteins such as Sorbitol dehydrogenase (SDH), the structure is believed to have evolved going from a ... networks between subunits has been shown to be important for the stability of the tetrameric quaternary protein structure. For ... could reveal an important hydrogen bonding network which stabilizes the tetrameric quaternary structure in mammalian SDH. In ...
*  Sorbitol dehydrogenase
... network between subunits has been shown to be important for the stability of the tetrameric quaternary protein structure. For ... For homotetrameric proteins such as SDH, the structure is believed to have evolved going from a monomeric to a dimeric and ... The SDH proteins have a close evolutionary relationship with alcohol dehydrogenase, which also belongs to the protein ... Structure. 11 (9): 1071-85. doi:10.1016/S0969-2126(03)00167-9. PMID 12962626. Ramachandran Plot Lovell, Davis, et al. Proteins ...
*  Protein trimer
Oligomer Protein quaternary structure Trimer (chemistry). ... In biochemistry, a protein trimer is a macromolecular complex ... Collagen is an example of homo-trimeric protein. Porins usually arrange themselves in membranes as trimers. ... formed by three, usually non-covalently bound, macromolecules like proteins or nucleic acids. A homo-trimer would be formed by ...
*  Morpheein
Tang, L.; Stith, L; Jaffe, EK (2005). "Substrate-induced Interconversion of Protein Quaternary Structure Isoforms". Journal of ... "Simultaneous optimization of enzyme activity and quaternary structure by directed evolution". Protein Science. 14 (8): 2103-14 ... 2001). "X-ray structure of HPr kinase: A bacterial protein kinase with a P-loop nucleotide-binding domain". The EMBO Journal. ... Tong, E. K.; Duckworth, Harry W. (1975). "Quaternary structure of citrate synthase from Escherichia coli K 12". Biochemistry. ...
*  Non-covalent interactions
As a whole, this is called a protein's quaternary structure. The quaternary structure is generated by the formation of ... Single tertiary protein structures can also assemble to form protein complexes composed of multiple independently folded ... Between 5 and 1000 milliseconds after protein folding initiation, three-dimensional structures of proteins, known as secondary ... The folding of most proteins from a primary (linear) sequence of amino acids to a three-dimensional structure is governed by ...
*  Protein structure prediction
The resulting score provides an indication as to whether or not the target protein might adopt such a structure. quaternary ... Protein design Protein function prediction Protein structure prediction software De novo protein structure prediction Molecular ... Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence-that ... A protein structure prediction method must explore the space of possible protein structures which is astronomically large. ...
*  Protein subunit
Protein quaternary structure Allostery Cooperativity Monomer Daniel M, Peek GW, Tollefsbol TO (2012). "Regulation of the human ... a protein subunit is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a protein ... for example microtubules and other cytoskeleton proteins. The subunits of a multimeric protein may be identical, homologous or ... A subunit is often named with a Greek or Roman letter, and the numbers of this type of subunit in a protein is indicated by a ...
*  MHC
... may refer to: Myosin heavy chain - part of the motor protein myosin's quaternary protein structure Major histocompatibility ...
*  Polyacrylamide gel electrophoresis
... thus overcoming some forms of tertiary protein folding, and breaking up quaternary protein structure (oligomeric subunits). ... By binding to the proteins the detergent destroys their secondary, tertiary and/or quaternary structure denaturing them and ... For proteins, sodium dodecyl sulfate (SDS) is an anionic detergent applied to protein samples to coat proteins in order to ... It is an anionic dye, which non-specifically binds to proteins. The structure of CBB is predominantly non-polar, and it is ...
*  List of MeSH codes (G06)
... protein conformation MeSH G06.184.603.790.709.550 --- protein structure, quaternary MeSH G06.184.603.790.709.600 --- protein ... protein structure, tertiary MeSH G06.184.603.790.709.610.380 --- hmg-box domains MeSH G06.184.603.790.709.610.480 --- kringles ... protein processing, post-translational MeSH G06.535.770.871.790.600.400 --- protein isoprenylation MeSH G06.535.770.871.790.600 ... protein MeSH G06.184.842.550 --- sequence homology, nucleic acid MeSH G06.184.842.550.830 --- synteny MeSH G06.184.850.400 --- ...
*  WHAT IF software
... homology modeling of protein tertiary structures and quaternary structures; validating protein structures, notably those ... Hooft, RW; Vriend, G; Sander, C; Abola, EE (23 May 1996). "Errors in protein structures". Nature. 381 (6580): 272. doi:10.1038/ ... correcting protein structures; visualising macromolecules and their interaction partners (for example, lipids, drugs, ions, and ... WHAT IF is a computer program used in a wide variety of computational (in silico) macromolecular structure research fields. The ...
*  Protein dimer
A protein dimer is a type of protein quaternary structure. A protein homodimer is formed by two identical proteins. A protein ... In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are ... Transcription factors Leucine zipper motif proteins Nuclear receptors 14-3-3 proteins G protein-coupled receptors G protein βγ- ... An exception is dimers that are linked by disulfide bridges such as the homodimeric protein NEMO. Some proteins contain ...
*  Colworth Medal
"The emergence of protein complexes: Quaternary structure, dynamics and allostery. Colworth Medal Lecture". Biochemical Society ... Collinson, I (2005). "The structure of the bacterial protein translocation complex SecYEG". Biochemical Society Transactions. ... Structural studies of reversible protein phosphorylation and protein phosphatases". Biochemical Society Transactions. 27 (6): ... Rouse, J (2009). "Control of genome stability by SLX protein complexes". Biochemical Society Transactions. 37 (Pt 3): 495-510. ...
*  Sarah Teichmann
"The emergence of protein complexes: quaternary structure, dynamics and allostery". Biochemical Society Transactions. 40 (3): ... Han, Jay (2007). Structure, function and evolution of protein-protein interactions (PhD thesis). University of Cambridge. ... Babu, M. M.; Luscombe, N. M.; Aravind, L; Gerstein, M; Teichmann, S. A. (2004). "Structure and evolution of transcriptional ... Gsponer, J; Futschik, M. E.; Teichmann, S. A.; Babu, M. M. (2008). "Tight regulation of unstructured proteins: From transcript ...
*  Albert J.R. Heck
... implemented novel technologies to study protein interactions and the formation of tertiary and quaternary protein structures. ... Within his research group, the two main lines of research are proteomics and native mass spectrometry of proteins and protein ... In proteomics, he is most renowned for his work on the analysis of post-translational modification of proteins using mass ... His group is among the pioneers of native mass spectrometry to study large protein assemblies and has developed and ...
*  Protein tertiary structure
A number of tertiary structures may fold into a quaternary structure. The science of the tertiary structure of proteins has ... Protein tertiary structure is the three dimensional shape of a protein. The tertiary structure will have a single polypeptide ... The protein tertiary structure is defined by its atomic coordinates. These coordinates may refer either to a protein domain or ... with one or more protein secondary structures, the protein domains. Amino acid side chains may interact and bond in a number of ...
*  Kaj Ulrik Linderstrøm-Lang
... tertiary and quaternary structure. Linderstrøm-Lang devoted himself unstintingly to protein science and trained a whole ... 1992) "Contribution of physical chemistry to an understanding of protein structure and function", Protein Sci., 1, 691-693. ... His most notable scientific contributions were the development of sundry physical techniques to study protein structure and ... and Linderstrøm-Lang K. (1949) "Salt Linkages in Proteins", Nature, 164, 411-412. Linderstrøm-Lang KU. (1952) "Proteins and ...
*  FLS2
Hutcheson (1997) found that the tertiary and quaternary structures of protein elicitors are dependent on elicitor activity. ... RLKs are transmembrane proteins that consists of inner, outer, and central membrane regions. Being proteins, they also have an ... In this domain, phosphorylation catalyzes a protein kinase cascade leading to a response . In FLS2, this response elicits ... The transmembrane domain is where proteins transition from extracellular to intracellular. This region is usually very ...
*  Nucleic acid structure
The quaternary structure of nucleic acids is similar to that of protein quaternary structure. Although some of the concepts are ... Nucleic acid structure prediction (computational) Nucleic acid thermodynamics Protein structure Krieger M, Scott MP, Matsudaira ... Also, the quaternary structure refers to the interactions between separate RNA units in the ribosome or spliceosome. Molecular ... Nucleic acid structure is often divided into four different levels: primary, secondary, tertiary and quaternary. Primary ...
*  Platelet factor 4
Barker S, Mayo KH (1995). "Quarternary [sic] structure amplification of protein folding differences observed in 'native' ... The gene for human PF4 is located on human chromosome 4. Platelet factor-4 is a 70-amino acid protein that is released from the ... 1995). "NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer". ... 1978). "Primary structure of human platelet factor 4". Thromb. Res. 11 (6): 893-898. doi:10.1016/0049-3848(77)90117-7. PMID ...
*  MODELLER
... is a computer program used for homology modeling to produce models of protein tertiary structures and quaternary structures ( ... The ModWeb comparative protein structure modeling webserver is based on Modeller and other tools for automatic protein ... List of protein structure prediction software Official website ModWeb EasyModeller - A GUI for Modeller. UCSF Chimera interface ... Martí-Renom MA, Stuart AC, Fiser A, Sánchez R, Melo F, Sali A (2000). "Comparative protein structure modeling of genes and ...
*  Intermolecular force
... and quaternary structures of proteins and nucleic acids. It also plays an important role in the structure of polymers, both ... Ege, Seyhan (2003) Organic Chemistry: Structure and Reactivity. Houghton Mifflin College. ISBN 0618318097. pp. 30-33, 67 " ...
*  Prostaglandin-endoperoxide synthase 2
The tertiary and quaternary structures of PTGS1 (COX-1) and PTGS2 (COX-2) enzymes are almost identical. Each subunit has three ... Picot D, Loll PJ, Garavito RM (January 1994). "The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1 ... PTGS (COX, which can be confused with "cytochrome oxidase") enzymes are monotopic membrane proteins; the membrane-binding ... of the protein. The catalytic domain is homologous to mammalian peroxidases such as myeloperoxidase. It has been found that ...