Serine/threonine-protein kinase PCTAIRE-1 is an enzyme that in humans is encoded by the PCTK1 gene. The protein encoded by this ... "Entrez Gene: PCTK1 PCTAIRE protein kinase 1". Cheng K, Li Z, Fu WY, Wang JH, Fu AK, Ip NY (Aug 2002). "Pctaire1 interacts with ... Graeser R, Gannon J, Poon RY, Dubois T, Aitken A, Hunt T (2002). "Regulation of the CDK-related protein kinase PCTAIRE-1 and ... Palmer KJ, Konkel JE, Stephens DJ (2005). "PCTAIRE protein kinases interact directly with the COPII complex and modulate ...
TRAF2 in turn recruits the multicomponent protein kinase IKK, enabling the serine-threonine kinase RIP to activate it. An ... This dissociation enables the adaptor protein TRADD to bind to the death domain, serving as a platform for subsequent protein ... This protein may use the morpheein model of allosteric regulation. TNF was thought to be produced primarily by macrophages, but ... Kant S, Swat W, Zhang S, Zhang ZY, Neel BG, Flavell RA, Davis RJ (2011). "TNF-stimulated MAP kinase activation mediated by a ...
Serine/threonine-protein kinase PAK 5 is an enzyme that in humans is encoded by the PAK5 gene. The PAK5 enzyme is one of three ... The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be ... members of Group II PAK family of serine/threonine kinases, and evolutionary conserved across species. The PAK5 was initially ... June 2014). "An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis". Human ...
Serine/threonine-protein kinase PCTAIRE-3 is an enzyme that in humans is encoded by the PCTK3 gene. GRCh38: Ensembl release 89 ... PCTK3 PCTAIRE protein kinase 3". Meyerson M, Enders GH, Wu CL, et al. (1992). "A family of human cdc2-related protein kinases ... Palmer KJ, Konkel JE, Stephens DJ (2005). "PCTAIRE protein kinases interact directly with the COPII complex and modulate ... 2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry". Mol. ...
BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene. GRCh38: Ensembl release 89: ... Sabater L, Gómez-Choco M, Saiz A, Graus F (Dec 2005). "BR serine/threonine kinase 2: a new autoantigen in paraneoplastic limbic ... "Entrez Gene: BRSK2 BR serine/threonine kinase 2". Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello ... "BRSK2 is activated by cyclic AMP-dependent protein kinase A through phosphorylation at Thr260". Biochemical and Biophysical ...
PITSLRE serine/threonine-protein kinase CDC2L1 is an enzyme that in humans is encoded by the CDC2L1 gene. This gene encodes a ... 2003). "The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase ... The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. ... 1990). "Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle". Proc. Natl. Acad. Sci. U.S.A. ...
This chimeric gene overproduces a fusion protein with excessive ALK activity. ALK is a serine/threonine-specific protein kinase ... This chimeric gene makes a CLTC-ALK fusion protein with uncontrolled ALK serine/threonine-specific protein kinase activity. ... ALK, i.e. anaplastic lymphoma kinase (also termed protein kinase B), is produced by the ALK gene. In IMT, the ALK gene has ... The fusion protein products of these chimeric genes, like those of ALK fusion proteins, are overproduced, overactive, and ...
The NHL repeats are also found in serine/threonine protein kinase (STPK) in diverse range of pathogenic bacteria. These STPK ... The NHL repeat has also been used to design a family of fully symmetrical 6-blade beta-propeller proteins called "Pizza". These ... The arthropod 'Brain Tumor' protein (Brat; Q8MQJ9) is one such growth regulator that contains a 6-bladed NHL-repeat beta- ... Kano S, Miyajima N, Fukuda S, Hatakeyama S (July 2008). "Tripartite motif protein 32 facilitates cell growth and migration via ...
Serine/threonine-protein kinase PFTAIRE-1 is an enzyme that in humans is encoded by the PFTK1 gene. PFTK1 has been shown to ... 2006). "A Cdc2-related protein kinase hPFTAIRE1 from human brain interacting with 14-3-3 proteins". Cell Res. 16 (6): 539-47. ... Lazzaro MA, Albert PR, Julien JP (Jul 1997). "A novel cdc2-related protein kinase expressed in the nervous system". J Neurochem ... "Entrez Gene: PFTK1 PFTAIRE protein kinase 1". Yang, Tao; Gao Yan-Kun; Chen Jiang-Ye (Jul 2002). "KIAA0202, a human septin ...
This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded ... Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10 ( ... "Entrez Gene: Calcium/calmodulin-dependent protein kinase ID". v t e (Articles with short description, Short description matches ... Human Calcium/calmodulin-dependent protein kinase type 1D (CAMK1D)) at the PDBe-KB. GRCh38: Ensembl release 89: ENSG00000183049 ...
The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and ... The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and ... Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene. PAK2 is one of three members of ... Serine/threonine-protein kinase PAK 2) at the PDBe-KB. (Articles with short description, Short description matches Wikidata, ...
Serine/threonine-protein kinase PCTAIRE-2 is an enzyme that in humans is encoded by the PCTK2 gene. The protein encoded by this ... PCTK2 PCTAIRE protein kinase 2". Meyerson M, Enders GH, Wu CL, et al. (1992). "A family of human cdc2-related protein kinases ... Hirose T, Tamaru T, Okumura N, Nagai K, Okada M (Dec 1997). "PCTAIRE 2, a Cdc2-related serine/threonine kinase, is ... gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to rat protein which is ...
SNF-related serine/threonine-protein kinase is an enzyme that in humans is encoded by the SNRK gene. GRCh38: Ensembl release 89 ... of a novel mammalian protein kinase harboring a homology domain that defines a subfamily of serine/threonine kinases". European ... "Cloning and characterization of human and mouse SNRK sucrose non-fermenting protein (SNF-1)-related kinases". Gene. 294 (1-2): ... "Entrez Gene: SNRK SNF related kinase". Thirugnanam K, Cossette SM, Lu Q, Chowdhury SR, Harmann LM, Gupta A, et al. (November ...
"Functional characterization of a novel Mn2+ dependent protein serine/threonine kinase KpnK, produced by Klebsiella pneumoniae ...
Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene. PAK6 belongs to the Group II PAK ... The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein ... The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved ... "Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase". The Journal of Biological Chemistry. 280 (5): ...
... belongs to the family of serine/threonine kinases that phosphorylate microtubule-associated proteins (MAP) causing their ... a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption". Cell ... a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption". Cell ... There are four members of the MARK protein family, MARK1-4, which are highly conserved. MARK4 kinase has been shown to be ...
AKT1 is under PANTHER protein class "non-receptor serine/threonine protein kinase" with class ID "PC00167". You can also see ... GO molecular function: This tell you what are the functions of your query gene; e.g. AKT1 has protein kinase activity and can ... PANTHER protein class: this gives you the names and IDs of PANTHER protein class for each of the genes; e.g. ... You must enter a protein sequence in the first box and the substitutions relative to this protein sequence in the second box; ...
... and interfering with various angiogenic related proteins such as integrins and serine/threonine-specific protein kinases. ... They include serine, aspartic, and cysteine-type proteases. A highly characterized example of the serine protease family is the ... "Structure-function analysis of the ADAM family of diintegrin-like and metalloproteinase-containing proteins". J. Protein Chem. ... Native proteins which contain such domains with regulatory activity are normally inactive, most likely because they are cryptic ...
Serine/threonine-protein kinases SGK represent a kinase subfamily with orthologs found across animal clades and in yeast ( ... This gene encodes a serine/threonine protein kinase that is highly similar to the rat serum-and glucocorticoid-induced protein ... a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and ... "Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic ...
... is a protein that in humans is encoded by the STK35 (serine/threonine kinase 35) gene. It is a member of the NKF4 (New ... "Entrez Gene: Serine/threonine kinase 35". Retrieved 2012-02-18. Vallenius T, Mäkelä TP (May 2002). "Clik1: a novel kinase ... Vallenius T, Mäkelä TP (May 2002). "Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein". ... Goyal P, Behring A, Kumar A, Siess W (2009). Randau L (ed.). "Identifying and characterizing a novel protein kinase STK35L1 and ...
In addition, this protein has been reported to negatively regulate the cell survival serine-threonine kinase AKT1. TRIB3 has ... The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. It is a ... 2003). "Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappaB activation and p53-induced ... 2004). "Human tribbles, a protein family controlling mitogen-activated protein kinase cascades". J. Biol. Chem. 279 (41): 42703 ...
The enzyme belongs to the serine/threonine protein kinase family and to the Ca2+/calmodulin-dependent protein kinase subfamily ... "Entrez Gene: CAMK2B calcium/calmodulin-dependent protein kinase (CaM kinase) II beta". Walikonis RS, Oguni A, Khorosheva EM, ... "Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha ... "KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent protein kinase II to ...
"The receptor-like protein-tyrosine phosphatase DEP-1 is constitutively associated with a 64-kDa protein serine/threonine kinase ... Geetha T, Wooten MW (February 2003). "Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve ... Also known as the ubiquitin-binding protein p62, it is an autophagosome cargo protein that targets other proteins that bind to ... "The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor". J. Biol. ...
"The receptor-like protein-tyrosine phosphatase DEP-1 is constitutively associated with a 64-kDa protein serine/threonine kinase ... The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling ... "Entrez Gene: PTPRJ protein tyrosine phosphatase, receptor type, J". Holsinger LJ, Ward K, Duffield B, Zachwieja J, Jallal B ( ... Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene. ...
Serine/threonine-protein kinase tousled-like 1 is an enzyme that in humans is encoded by the TLK1 gene. The Tousled-like ... kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation ... Schultz SJ, Nigg EA (Oct 1993). "Identification of 21 novel human protein kinases, including 3 members of a family related to ... "cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear ...
PAS domain-containing serine/threonine-protein kinase is an enzyme that in humans is encoded by the PASK gene. PAS domains ... "Entrez Gene: PASK PAS domain containing serine/threonine kinase". Nakajima D, Okazaki N, Yamakawa H, et al. (2003). " ... a PAS-serine/threonine kinase related to bacterial oxygen sensors" (PDF). Biochem Biophys Res Commun. 288 (4): 757-64. doi: ... an evolutionarily conserved PAS domain-regulated serine/threonine kinase". Proc Natl Acad Sci U S A. 98 (16): 8991-6. Bibcode: ...
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases, a subfamily ... A novel member of the protein kinase D family of serine threonine kinases". J Biol Chem. 276 (5): 3310-8. doi:10.1074/jbc. ... Serine/threonine-protein kinase D2 or PKD2 is an enzyme that in humans is encoded by the PRKD2 gene. ... PRKD2 protein kinase D2". Sturany S, Van Lint J, Gilchrist A, et al. (2002). "Mechanism of activation of protein kinase D2(PKD2 ...
Testis-specific serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the TSSK2 gene. GRCh38: Ensembl ... "Expression analysis of the human testis-specific serine/threonine kinase (TSSK) homologues. A TSSK member is present in the ... "A novel family of serine/threonine kinases participating in spermiogenesis". J. Cell Biol. 139 (7): 1851-1859. doi:10.1083/jcb. ... "Entrez Gene: TSSK2 testis-specific serine kinase 2". Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ...
"Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated ... binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". The ... binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". The ... Replication factor C subunit 2 is a protein that in humans is encoded by the RFC2 gene. The elongation of primed DNA templates ...
Microtubule-associated serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MAST1 gene. GRCh38: ... "Entrez Gene: MAST1 microtubule associated serine/threonine kinase 1". Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in ... 2003). "Sast124, a novel splice variant of syntrophin-associated serine/threonine kinase (SAST), is specifically localized in ... 1999). "Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases". Nat. Neurosci ...