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*  Surfactant protein C
Solarin KO, Wang WJ, Beers MF (2002). "Synthesis and post-translational processing of surfactant protein C". Pediatric ... Surfactant protein C (SP-C), is one of the pulmonary surfactant proteins. In humans this is encoded by the SFTPC gene. It is a ... "Lipid-protein interactions of hydrophobic proteins SP-B and SP-C in lung surfactant assembly and dynamics". Pediatric pathology ... Keller A, Eistetter HR, Voss T, Schafer KP (Aug 1991). "The pulmonary surfactant protein C (SP-C) precursor is a type II ...
*  Tenomodulin
It has been suggested that BRICHOS participates in the protein post-translational processing, however the exact function ... Protein analyses in eye and periodontal ligament revealed full length TNMD protein as a double band of 40 and 45 kDa. It has ... The last exon of TNMD gene encodes the conserved C-terminal cysteine-rich domain, which makes up the part of the protein ... Tenomodulin (also referred to as tendin, myodulin, Tnmd and TeM) is a protein encoded by the TNMD (Tnmd) gene and was ...
*  ACADSB
The open reading frame (ORF) encodes a precursor protein that contains 431 amino acids; post-translational processing results ... The encoded protein is also involved in L-leucine catabolism. Mutations in the ACADSB gene have been associated with 2- ... with the mutations causing exon skipping and other transcriptional and translational errors. The disorder may be detected by MS ... in a mature protein with 399 amino acids. The cDNA is significantly similar to the cDNA of other members of the acyl-CoA ...
*  Proteoglycan 4
"Consequences of disease-causing mutations on lubricin protein synthesis, secretion, and post-translational processing". The ... "Cartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions ... The protein encoded by this gene is a approximately 345 kDa specifically synthesized by chondrocytes located at the surface of ... The cDNA encodes a protein of 1,404 amino acids (human A isoform) with a somatomedin B homology domain, heparin-binding domains ...
*  Cycle (gene)
"Cytoplasmic interaction with CYCLE promotes the post-translational processing of the circadian CLOCK protein". FEBS Letters. ... CYC also plays a role in the post-translational regulation of CLK in the cytoplasm. These four proteins of the feedback loop ... However, to fully understand these processes, work must be done to identify downstream interactions of CYCLE proteins. In ... The TIM protein in these complexes mediate the accumulation of the dimeric PER-TIM protein complex and their subsequent ...
*  Golgi apparatus
Much of the enzymatic processing is post-translational modification of proteins. For example, phosphorylation of ... Other general post-translational modifications of proteins include the addition of carbohydrates (glycosylation) and phosphates ... It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach ... Individual stacks have different assortments of enzymes, allowing for progressive processing of cargo proteins as they travel ...
*  S-Nitrosothiol
This is a reversible process and a major form of posttranslational modification of proteins. S-Nitrosated proteins (SNOs) serve ... post-translational modification leads to changes in protein activity, protein interactions, or subcellular location of target ... The addition of a nitroso group to a sulfur atom of an amino acid residue of some protein is known as S-nitrosylation or S- ... proteins; all major classes of proteins can undergo S-nitrosylation; and enzymes play a primary role in regulation of S- ...
*  Epigenetics in stem-cell differentiation
... express a unique complement of in the enzymatic processes in post-translational glycosylation of proteins. In normal stem cells ... Numerous proteins can physically interact with DNMTs themselves, which help target DNMT1 to hemi-methylated DNA. Several new ... In order to analyze the process of HDAC knockout mouse in detail, the knockout mice embryonic stem cells were used to generate ... Future studies will be needed to further clarify the certain mechanism pathways such as DNA binding proteins, DNA repair and ...
*  Epigenomics
... post-translational processing and degradation. Regulatory proteins that bind to DNA, RNA, and/or proteins are key effectors in ... Chromatin remodeling occurs via post-translational modifications of the N-terminal tails of core histone proteins. The ... The process can be reversed through removal of histone acetyl groups by deacetylases. The second process involves the ... which is translated to proteins, which perform cellular processes and functions. A paradox exists, however, in that cells ...
*  Latrotoxin
This precursor molecule undergoes post-translational processing where the eventual, active α-LTX protein (131.5 kDa) is formed ... which mediate protein-protein interactions, the α-LTX monomer forms a dimer with another α-LTX monomer under normal conditions ... protein tyrosine phosphatase sigma (PTPσ). The toxin stimulates a receptor, most likely latrophilin, which is a G-protein ... The α-LTX protein tertiary structure can be divided in three parts: the N-terminal wing (36 kDa), the body (76 kDa), and the C- ...
*  Hydrogenase maturation protease family
This precursor undergoes a complex post-translational maturation process that requires a number of accessory proteins. At one ... Gene/protein names are sometimes used interchangeably to designate various "hydrogenase cluster" proteins unrelated to each ... For example, the following names are used for members of this group, but also for unrelated proteins: HupD is used in ... For example, Escherichia coli HycI is involved in processing of pre-HycE (the large subunit of hydrogenase 3),; HybD is ...
*  List of MeSH codes (G05)
... protein processing, post-translational MeSH G05.315.670.600.400 --- protein isoprenylation MeSH G05.315.670.600.700 --- protein ... splicing MeSH G05.315.700 --- rna processing, post-transcriptional MeSH G05.315.700.225 --- rna 3' end processing MeSH G05.315. ... protein biosynthesis MeSH G05.310.700 --- transcription, genetic MeSH G05.310.700.500 --- reverse transcription MeSH G05.315. ...
*  Spine apparatus
proposed that the spine apparatus may be involved in post-translational protein processing, similar to that observed in the ... short-term plasticity which requires post-translational protein modifications, but is protein synthesis independent), LTP2 ( ... The spine apparatus has also been shown to be involved in the post-translational processing and spatial delivery of NMDA ... and function in the post-translational processing of GluR1 and GluR2 subunits, which are locally translated in dentritic spines ...
*  RNA splicing
Post-translational protein splicing and other lessons from the school of antigen processing". Journal of Molecular Medicine. 83 ... In many cases, the splicing process can create a range of unique proteins by varying the exon composition of the same mRNA. ... cDNA post-transcriptional modification mRNA capping polyadenylation Exon Junction Complex SWAP protein domain, a splicing ... DNA damage affects splicing factors by altering their post-translational modification, localization, expression and activity. ...
*  Proteasome
... especially when the proteasome plays a normal role in the post-translational processing of the protein. The proteasomal ... for some proteins, the unfolding process is rate-limiting, while deubiquitination is the slowest step for other proteins. The ... The involvement of the proteasome in this process is indicated by both the increase in protein ubiquitination, and of E1, E2, ... Rape M, Jentsch S (May 2002). "Taking a bite: proteasomal protein processing". Nature Cell Biology. 4 (5): E113-6. doi:10.1038/ ...
*  Gene
... expression can be regulated at any step: from transcriptional initiation, to RNA processing, to post-translational ... Translation is the process by which a mature mRNA molecule is used as a template for synthesizing a new protein. Translation is ... The process of producing a biologically functional molecule of either RNA or protein is called gene expression, and the ... A typical protein-coding gene is first copied into RNA as an intermediate in the manufacture of the final protein product. In ...
*  Regulation of gene expression
... and to the post-translational modification of a protein. Often, one gene regulator controls another, and so on, in a gene ... These processes occur in eukaryotes but not in prokaryotes. This modulation is a result of a protein or transcript that, in ... from the DNA-RNA transcription step to post-translational modification of a protein. The following is a list of stages where ... Conversely, down-regulation is a process resulting in decreased gene and corresponding protein expression. Up-regulation occurs ...
*  Green fluorescent protein
This process of post-translational modification is referred to as maturation. The hydrogen-bonding network and electron- ... GFP alone does not interfere with biological processes, but when fused to proteins of interest, careful design of linkers is ... Analysis of such time lapse movies has redefined the understanding of many biological processes including protein folding, ... The green fluorescent protein (GFP) is a protein composed of 238 amino acid residues (26.9 kDa) that exhibits bright green ...
*  Carboxypeptidase
... they help to mature proteins (e.g., Post-translational modification) or regulate biological processes. For example, the ... end of a protein or peptide. (Contrast with an aminopeptidase, which cleaves peptide bonds at the other end of the protein.) ... and many other processes. Carboxypeptidases are usually classified into one of several families based on their active site ... and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation ...
*  Citrullination
... because it takes place on the protein after the DNA is translated. The role of post-translational processing in gene regulation ... This process is known as post-translational processing or post-translational modification, ... Instead, it is the result of a post-translational modification. Citrullination is distinct from the formation of the free amino ... This increases the hydrophobicity of the protein, which can lead to changes in protein folding, affecting the structure and ...
*  Amyloid precursor protein
... similarities in post-translational processing have invited comparisons to the signaling role of the surface receptor protein ... Ling Y, Morgan K, Kalsheker N (Nov 2003). "Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance ... De Strooper B, Annaert W (Jun 2000). "Proteolytic processing and cell biological functions of the amyloid precursor protein". ... APP undergoes extensive post-translational modification including glycosylation, phosphorylation, sialylation, and tyrosine ...
*  Protein S
"Human protein S cDNA encodes Phe-16 and Tyr 222 in consensus sequences for the post-translational processing". FEBS Lett. 222 ( ... Protein S is partly homologous to other vitamin K-dependent plasma coagulation proteins, such as protein C and factors VII, IX ... Dahlbäck B (1991). "Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant ... Protein C und Protein S" [Molecular biological basis and diagnosis of hereditary defect of antithrombin III, protein c and ...
*  Dolichol
In addition, dolichols can be adducted to proteins as a posttranslational modification, a process in which branched ... Dolichols play a role in the co-translational modification of proteins known as N-glycosylation in the form of dolichol ... However, the cellular process they are involved in is not glycosylation, but instead cell wall biosynthesis. Statins decrease ... protein glycosylation in Crenarchaeota". Biochemical Society Transactions. 41 (1): 384-392. doi:10.1042/BST20120296. ISSN 0300- ...
*  Protein
Some enzymes act on other proteins to add or remove chemical groups in a process known as posttranslational modification. About ... Shortly after or even during synthesis, the residues in a protein are often chemically modified by post-translational ... ISBN 0-8053-3931-0. The Protein Naming Utility NCBI Entrez Protein database NCBI Protein Structure database Human Protein ... fibrous proteins, and membrane proteins. Almost all globular proteins are soluble and many are enzymes. Fibrous proteins are ...
*  Glutamate-cysteine ligase
... translational (processing of the mRNA into protein), and posttranslational levels (involving modifications to the existing ... 2009). "Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ... 2009). "Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ... 2009). "Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ...
*  Phage display
... in producing post-translational modifications present in eukaryotic cells or by the misfolding of multi-domain proteins. While ... Some proteins cannot undergo this process and therefore cannot be displayed on the surface of Ff phages. In these cases, T7 ... Phage display is a laboratory technique for the study of protein-protein, protein-peptide, and protein-DNA interactions that ... a gene encoding a protein of interest is inserted into a phage coat protein gene, causing the phage to "display" the protein on ...