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*  Protein kinase C
... membrane-bound receptor for activated protein kinase C proteins). The protein kinase C enzymes are known for their long-term ... Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in ... The consensus sequence of protein kinase C enzymes is similar to that of protein kinase A, since it contains basic amino acids ... Serine/threonine-specific protein kinase Signal transduction Yasutomi Nishizuka, discovered protein kinase C Wilson CH, Ali ES ...
*  Protein kinase
One very important group of protein kinases are the MAP kinases (acronym from: "mitogen-activated protein kinases"). Important ... Hanks SK, Hunter T (May 1995). "Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain ... The human protein kinase family is divided into the following groups: AGC kinases - containing PKA, PKC and PKG. CaM kinases - ... A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation ...
*  Protein kinase domain
The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. ... Hanks SK, Hunter T (May 1995). "Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain ... Protein kinase function has been evolutionarily conserved from Escherichia coli to Homo sapiens. Protein kinases play a role in ... Protein kinases are a group of enzymes that move a phosphate group onto proteins, in a process called phosphorylation. This ...
*  Protein kinase N1
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G ... "A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase ... "A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta ... This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 ( ...
*  Protein kinase D1
Serine/threonine-protein kinase D1 is an enzyme that in humans is encoded by the PRKD1 gene. Members of the protein kinase D ( ... "The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C". J. Biol ... Holmes AM (1996). "In vitro phosphorylation of human immunodeficiency virus type 1 Tat protein by protein kinase C: evidence ... "Bruton's tyrosine kinase (Btk) associates with protein kinase C mu". FEBS Lett. 461 (1-2): 68-72. doi:10.1016/s0014-5793(99) ...
*  Protein kinase inhibitor
A protein kinase inhibitor is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases ... the tyrosine kinases act on tyrosine, and a number (dual-specificity kinases) act on all three. There are also protein kinases ... and protein kinase inhibitors can be used to treat diseases due to hyperactive protein kinases (including mutant or ... Some of the kinase inhibitors used in treating cancer are inhibitors of tyrosine kinases. The effectiveness of kinase ...
*  Protein kinase A
... is directed to specific sub cellular locations after tethering to Protein kinase A anchoring proteins (AKAPs ... Protein kinase Signal transduction G protein-coupled receptor Serine/threonine-specific protein kinase Myosin light-chain ... out of 540 different protein kinase genes that make up for human kinome, only one other protein kinase, Casein kinase 2, is ... Protein kinase A, more precisely known as adenosine 3',5'-monophosphate (cyclic AMP)-dependent protein kinase was discovered by ...
*  Myotonin-protein kinase
... (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase ( ... Myotonin-protein kinase is a serine-threonine kinase that is closely related to other kinases that interact with members of the ... Dystrophia myotonica protein kinase (DMPK) is a serine/threonine kinase composed of a kinase domain and a coiled-coil domain ... The dmpk gene product is a Ser/Thr protein kinase homologous to the MRCK p21-activated kinases and the Rho family of kinases. ...
*  Protein kinase B
... including integrin-linked kinase (ILK) and mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK2) can also ... Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple ... For example, PI 3-kinases may be activated by a G protein coupled receptor or receptor tyrosine kinase such as the insulin ... Yang ZZ, Tschopp O, Baudry A, Dümmler B, Hynx D, Hemmings BA (April 2004). "Physiological functions of protein kinase B/Akt". ...
*  Tau-protein kinase
... protein tau kinase, STK31, tau kinase, [tau-protein] kinase, tau-protein kinase I, tau-protein kinase II, tau-tubulin kinase, ... Human genes encoding proteins with Tau-protein kinase activity include: BRSK1 BRSK2 GSK3A GSK3B Ishiguro K, Ihara Y, Uchida T, ... In enzymology, a tau-protein kinase (EC 2.7.11.26) is an enzyme that catalyzes the chemical reaction ATP + tau protein ⇌ {\ ... Other names in common use include ATP:tau-protein O-hosphotransferase, brain protein kinase PK40erk, cdk5/p20, CDK5/p23, ...
*  Protein kinase R
... NA-activated also known as protein kinase R (PKR), interferon-induced, double-stranded RNA-activated protein ... Patel RC, Sen GC (August 1998). "PACT, a protein activator of the interferon-induced protein kinase, PKR". EMBO J. 17 (15): ... "The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient ... "Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo". Proc. Natl. Acad ...
*  Rho-associated protein kinase
... (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine kinases. It is ... DMPK-related cell division control protein 42 (Cdc42)-binding kinases (MRCK) and citron kinase. All of these kinases are ... August 1999). "Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase". Science. 285 (5429): ... glial fibrillaric acidic protein), NF-L (neurofilament L protein) F-actin binding proteins: Adducin, EF-1α (elongation factor, ...
*  CGMP-dependent protein kinase
... or Protein Kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP ... EC 2.7.11.12 Cyclic GMP-Dependent Protein Kinases and the Cardiovascular System cGMP-Dependent Protein Kinases at the US ... suppression of the kinase activity in the absence of cGMP, and interactions with other proteins including protein substrates (2 ... cAMP-dependent protein kinase PDB: 3NMD​; Casteel DE, Smith-Nguyen EV, Sankaran B, Roh SH, Pilz RB, Kim C (October 2010). "A ...
*  Tyrosine-protein kinase BLK
... microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase". Mol. Cell. Biol. 13 (9): ... Tyrosine-protein kinase BLK also known as B lymphocyte kinase is an enzyme that in humans is encoded by the BLK gene. The ... 1993). "Mapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector ... 1996). "In vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylation ...
*  Tyrosine-protein kinase CSK
... also known as C-terminal Src kinase is an enzyme that, in humans, is encoded by the CSK gene. This ... Universal protein resource accession number P41240 for "Tyrosine-protein kinase CSK" at UniProt. Bräuninger A, Holtrich U, ... and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases". Growth Factors. 23 (3): 233-44 ... "Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell ...
*  AMP-activated protein kinase
It should not be confused with cyclic AMP-activated protein kinase (protein kinase A). AMPK is a heterotrimeric protein complex ... "AMP-activated protein kinase kinase activity and phosphorylation of AMP-activated protein kinase in contracting muscle of ... 5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that ... "Endurance training increases LKB1 and MO25 protein but not AMP-activated protein kinase kinase activity in skeletal muscle". Am ...
*  Mitogen-activated protein kinase
Signal transduction MAP kinase kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase MAPK1 (ERK2) MAPK3 (ERK1) MAPK7 ... A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine ... MAP Kinase Resource . Table of names for mitogen-activated kinases. MAPK cascade picture Mitogen-Activated Protein Kinases at ... is performed by members of the Ste7 protein kinase family, also known as MAP2 kinases. MAP2 kinases in turn, are also activated ...
*  Wee1-like protein kinase
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This ... Wee1-like protein kinase has been shown to interact with YWHAB and PIN1. GRCh38: Ensembl release 89: ENSG00000166483 - Ensembl ... WEE1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) Kino T, Pavlakis GN (2004). "Partner ... protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition ...
*  Cdc42 binding protein kinase beta
... is a protein that in humans is encoded by the CDC42BPB gene. This gene encodes a member of ... The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this ... CDC42 binding protein kinase beta". Retrieved 2017-05-31. Choi SH, Czifra G, Kedei N, Lewin NE, Lazar J, Pu Y, Marquez VE, ... myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta". J. Biol. Chem. 283 (16): 10543-9. doi:10.1074/jbc. ...
*  Mitogen-activated protein kinase 9
... a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase ... The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple ... a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway". ... "The JIP group of mitogen-activated protein kinase scaffold proteins". Molecular and Cellular Biology. 19 (10): 7245-54. doi: ...
*  Protein kinase C zeta type
"Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1". Science. 281 (5385): 2042-5 ... "Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications ... "A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta ... Protein kinase C, zeta (PKCζ), also known as PRKCZ, is a protein that in humans is encoded by the PRKCZ gene. The PRKCZ gene ...
*  Mitogen-activated protein kinase kinase
Signal transduction MAP kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase Dérijard B, et al. (1995). "Independent ... Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a kinase enzyme which phosphorylates mitogen- ... Mitogen-Activated Protein Kinase Kinases at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... activated protein kinase (MAPK). MAP2K is classified as EC 2.7.12.2. There are seven genes: MAP2K1 (a.k.a. MEK1) MAP2K2 (a.k.a ...
*  Serine/threonine-specific protein kinase
A serine/threonine protein kinase (EC 2.7.11.1) is a kinase enzyme that phosphorylates the OH group of serine or threonine ( ... Serine/threonine protein kinase p90-kDa ribosomal S6 kinase (RSK) is in involved in development of some prostate cancers. Raf ... When the pseudosubstrate is removed, the kinase can perform its normal function. 65 Many serine/threonine protein kinases do ... Receptor protein serine/threonine kinase) and Intracellular signaling peptides and proteins. Of the latter, types include: ...
*  Goodpasture-antigen-binding protein kinase
Other names in common use include GPBPK, GPBP kinase, STK11, and Goodpasture antigen-binding protein kinase. This enzyme ... protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[Goodpasture antigen-binding protein] ... In enzymology, a Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) is an enzyme that catalyzes the chemical reaction ATP ... Vieites B, Granero F, Forteza J, Saus J (2000). "Goodpasture antigen-binding protein, the kinase that phosphorylates the ...
*  Protein kinase, AMP-activated, alpha 1
"Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase". J. ... The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP- ... 1996). "Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the ... Bolster DR, Crozier SJ, Kimball SR, Jefferson LS (2002). "AMP-activated protein kinase suppresses protein synthesis in rat ...
*  UCKL1
2002). "Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase ... Uridine-cytidine kinase-like 1 is an enzyme that in humans is encoded by the UCKL1 gene. GRCh38: Ensembl release 89: ... 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. ... UCKL1 uridine-cytidine kinase 1-like 1". Beausoleil SA, Villén J, Gerber SA, et al. ( ...