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*  Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that perform the same or similar ... Each unique sequence produces a specific form of a protein. A set of protein isoforms may also result from a set of closely ... This is precisely the normal isoform ratio in hyperplasia. Only one of these isoforms is found during neoplasia. Gene isoform ... Pathoma, Fundamentals of Pathology MeSH entry protein isoforms Definitions Isoform. ...
*  40S ribosomal protein S4, Y isoform 1
... is a protein that in humans is encoded by the RPS4Y1 gene. Cytoplasmic ribosomes, ... This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein ... Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ... and Y-encoded isoforms of ribosomal protein S4 consistent with a role in Turner syndrome". Nat. Genet. 4 (3): 268-71. doi: ...
*  40S ribosomal protein S4, Y isoform 2
This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein ... Ribosomal protein S4, Y-linked 2 also known as RPS4Y2 is a protein which in humans is encoded by the RPS4Y2 gene which resides ... Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ... "Entrez Gene: RPS4Y2 ribosomal protein S4, Y-linked 2". Andrés O, Kellermann T, López-Giráldez F, Rozas J, Domingo-Roura X, ...
*  C2orf73
The protein has a molecular mass of 32,142 Daltons. There are four protein isoforms. The primary isoform (X1) is 287 amino ... Uncharacterized protein C2orf73 is a protein that in humans is encoded by the C2orf73 gene. The protein is predicted to be ... The PELE tool on Biology Wrokbench predicts three likely α-helices and one β-strand in the protein. The GPS, NetPhos, MyHits ... Three proteins have been experimentally determined to interact with C2orf73 through Yeast Two-Hybrid experiments. FCH and ...
*  Arachidonate 5-lipoxygenase
Ochs MJ, Suess B, Steinhilber D (2014). "5-lipoxygenase mRNA and protein isoforms". Basic & Clinical Pharmacology & Toxicology ... ALOX5 binds with the F actin-binding protein, coactin-like protein. Based on in vitro studies, this protein binding serves to ... protein kinase A (PKA), protein kinase C, Cdc2, and/or a Ca2+/calmodulin-dependent protein kinase; b) moves to bind with ... Coactin-like protein (COL1), and Dicer protein A PLAT domain within its C2-like domain; this domain, by analogy to other PLAT ...
*  Actin, alpha 1
"Entrez Gene: ACTA1 actin, alpha 1, skeletal muscle". Bandman, E (1992). "Contractile protein isoforms in muscle development". ... Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene. Actin alpha 1 which is expressed in ... Bretscher A, Weber K (1980). "Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a ... SRF may bring a number of other proteins to the promoter of skeletal actin, such as andogen receptor, and thereby contribute to ...
*  DIAPH2
Alternative splicing results in two protein isoforms. DIAPH2 has been shown to interact with RhoD. GRCh38: Ensembl release 89: ... Protein diaphanous homolog 2 is a protein that in humans is encoded by the DIAPH2 gene. This gene may play a role in the ... Satoh S, Tominaga T (2001). "mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber ... Eisenmann KM, Harris ES, Kitchen SM, Holman HA, Higgs HN, Alberts AS (2007). "Dia-interacting protein modulates formin-mediated ...
*  Embryonal fyn-associated substrate
... isoform 2, containing 5 exons and encoding a shorter protein (468 amino acids in length); and isoform 3, containing 6 exons and ... allowing the CAS protein to function as a scaffold for other proteins including CRK proteins and C3G, a guanine nucleotide ... There are three protein isoforms of human Efs. hEfs1 and hEfs2 were identified by Ishino et al. hEFS1 (561 aa) represents the ... In humans, the 561 amino acid EFS protein acts as a scaffolding protein for cell signaling based on interactions with SRC, FAK ...
*  Emery-Dreifuss muscular dystrophy
Ziat, Esma; Bertrand, Anne T. (2015-01-01). "FHL1 protein isoforms in Emery-Dreifuss muscular dystrophy". Orphanet Journal of ... The EMD and LMNA genes provide instructions for making proteins that are components of the nuclear envelope, which surrounds ... update 2011 "OMIM Entry - * 608441 - SPECTRIN REPEAT-CONTAINING NUCLEAR ENVELOPE PROTEIN 1; SYNE1". www.omim.org. Retrieved 19 ... "OMIM Entry - * 608442 - SPECTRIN REPEAT-CONTAINING NUCLEAR ENVELOPE PROTEIN 2; SYNE2". www.omim.org. Retrieved 19 May 2016. " ...
*  Arylsulfatase E
Urbitsch P, Salzer MJ, Hirschmann P, Vogt PH (2000). "Arylsulfatase D gene in Xp22.3 encodes two protein isoforms". DNA Cell ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ...
*  HDAC3
"The histone deacetylase 9 gene encodes multiple protein isoforms". J. Biol. Chem. 278 (18): 16059-72. doi:10.1074/jbc. ... "Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3". EMBO J. 19 (16): 4342-50. doi: ... HDAC3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... Nicolas E, Ait-Si-Ali S, Trouche D (August 2001). "The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein ...
*  Plakophilin-2
Alternately spliced transcripts encoding protein isoforms have been identified. Plakophilin 2 localizes to cell desmosomes and ... "Protein sequence of human PKP2 (Uniprot ID: Q99959-2)". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). Retrieved 11 ... Plakophilin-2 is a member of the armadillo repeat and plakophilin protein family. Plakophilin proteins contain nine central, ... Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. Plakophilin 2 is expressed in skin and cardiac muscle, ...
*  STK36
2005). "The FU gene and its possible protein isoforms". BMC Genomics. 5 (1): 49. doi:10.1186/1471-2164-5-49. PMC 512281 . PMID ... Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ... Serine/threonine-protein kinase 36 is an enzyme that in humans is encoded by the STK36 gene. STK36 has been shown to interact ...
*  HDAC9
"The histone deacetylase 9 gene encodes multiple protein isoforms". The Journal of Biological Chemistry. 278 (18): 16059-72. doi ... "The histone deacetylase 9 gene encodes multiple protein isoforms". The Journal of Biological Chemistry. 278 (18): 16059-72. doi ... The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous ... HDAC9 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ...
*  SIN3B
"The histone deacetylase 9 gene encodes multiple protein isoforms". The Journal of Biological Chemistry. 278 (18): 16059-72. doi ... Paired amphipathic helix protein Sin3b is a protein that in humans is encoded by the SIN3B gene. SIN3B has been shown to ... SIN3B protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (3): ...
*  CABYR
Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully ... Calcium-binding tyrosine phosphorylation-regulated protein is a protein that in humans is encoded by the CABYR gene. To reach ... Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation". J ... involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to ...
*  SUMO2
"The histone deacetylase 9 gene encodes multiple protein isoforms". The Journal of Biological Chemistry. 278 (18): 16059-72. doi ... Small ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. This gene encodes a protein that ... However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, ... "In vitro modification of human centromere protein CENP-C fragments by small ubiquitin-like modifier (SUMO) protein: definitive ...
*  40S ribosomal protein S24
Alternative splice variants that encode different protein isoforms exist. As is typical for genes encoding ribosomal proteins, ... 40S ribosomal protein S24 is a protein that in humans is encoded by the RPS24 gene. Ribosomes, the organelles that catalyze ... This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ... 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs ...
*  Nuclear receptor co-repressor 1
"The histone deacetylase 9 gene encodes multiple protein isoforms". J. Biol. Chem. 278 (18): 16059-72. doi:10.1074/jbc. ... is a protein that in humans is encoded by the NCOR1 gene. NCOR1 is a transcriptional coregulatory protein which contains ... "Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3". EMBO J. 19 (16): 4342-50. doi: ... It is a member of the family of nuclear receptor corepressors; the other human protein that is a member of that family is ...
*  Gene isoform
Isoforms harboring changes in the CDS have been the most thoroughly characterized because they commonly give rise to proteins ... Protein isoform Mitchell PJ, Tjian R (July 1989). "Transcriptional regulation in mammalian cells by sequence-specific DNA ... Four Atf3 isoforms were identified in dorsal root ganglia (DRG) so far. These four isoforms differ in TSS, and one differs in ... UTR compared to the conventional Pten isoform expressed within neurons. The truncated CDS encodes a protein that lacks a ...
*  Antifreeze protein
Leinala EK, Davies PL, Doucet D, Tyshenko MG, Walker VK, Jia Z (September 2002). "A beta-helical antifreeze protein isoform ... Antifreeze proteins (AFPs) or ice structuring proteins (ISPs) refer to a class of polypeptides produced by certain vertebrates ... They are alpha helical proteins rich in glutamate and glutamine. This protein is approximately 12KDa in size and consists of a ... Jorov A, Zhorov BS, Yang DS (June 2004). "Study of interaction of winter flounder antifreeze protein with ice". Protein Sci. 13 ...
*  C8orf58 (protein)
C8orf58 protein Isoform 1 is 365 amino acids long. Isoform 2 and Isoform 3 are 357 and 300 amino acids respectively. There is a ... Uncharacterized protein C8orf58 is a protein in humans that is encoded by the C8orf58 gene. The protein is predicted to be ... Uncharacterized protein C8orf58 isoform 1 [Homo sapiens].[4] SDSC Biology Workbench Chou-Fasman Secondary Structure Prediction ... Two proteins have been found to interact with protein C8orf58, CENPH and metG1, which were found using two hybrid assay and the ...
*  Nucleoporin 155
Two protein isoforms are encoded by transcript variants of this gene. NUP155 has been shown to interact with GLE1L. GRCh38: ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038 ... The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277-86. doi: ...
*  ZRF1
This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been ... DnaJ homolog subfamily C member 2 is a protein that in humans is encoded by the DNAJC2 gene. This gene is a member of the M- ... This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also ... The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for ...
*  METTL2B
Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been ... Methyltransferase-like protein 2B is an enzyme that in humans is encoded by the METTL2B gene. This gene is a member of a family ... 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and ... transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMC 403697 . PMID ...
*  NFIX
... has been shown to interact with SKI protein and it is also known to interact with AP-1. NFI-X3 has been shown to interact ... Apt D, Liu Y, Bernard HU (1994). "Cloning and functional analysis of spliced isoforms of human nuclear factor I-X: interference ... Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, regulates ... NFIX protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ...