Wikimedia Commons has media related to Protein interaction mapping. Protein-Protein Interaction Databases Library of Modulators ... complex Protein domain dynamics Protein flexibility Protein structure Protein-protein interaction prediction Protein-protein ... Visualization and integration of protein-protein interactions. In: Golemis, E. (ed.) protein-Protein Interactions - A Molecular ... To test protein-protein interaction, the targeted protein cDNA and query protein cDNA were immobilized in a same coated slide. ...
Overall, the electrostatic potential maps follow the prevalence trend of Trp >> Tyr > ( Phe ) > His {\displaystyle {\ce {Trp ... Glycan-Protein interactions represent a class of biomolecular interactions that occur between free or protein-bound glycans and ... Intramolecular glycan-protein (protein-glycan) interactions occur between glycans and proteins that they are covalently ... Together with protein-protein interactions, they form a mechanistic basis for many essential cell processes, especially for ...
Protein-protein interaction Interactome data; Genetic regulatory relationships; Details of intra- and inter-specific sequence ... There is a coordinate re-mapping program and mapping data are available to aid these comparisons. All the gene-sets of the ... The protein products of gene are created by translating the CDS sequences. Each unique protein sequence is given a unique ... Genetic maps, markers and polymorphisms; The C. elegans physical map; Gene expression profiles (stage, tissue and cell) from ...
Mehla J, Caufield JH, Uetz P (May 2015). "The yeast two-hybrid system: a tool for mapping protein-protein interactions". Cold ... Protein-protein docking, the prediction of protein-protein interactions based only on the three-dimensional protein structures ... Bio-layer interferometry (BLI) is a label-free technology for measuring biomolecular interactions (protein:protein or protein: ... Fluorescence polarization/anisotropy can be used to measure protein-protein or protein-ligand interactions. Typically one ...
... he guided establishment of a protein interaction map for cell polarity development, and determined a network of interactions ... "A protein interaction map for cell polarity development". Kaksonen, Marko; Toret, Christopher P.; Drubin, David G. (2005). "A ... Drubin studied mutants of over 60 proteins, identifying a pathway in budding yeast in which proteins are recruited to endocytic ... He extended these studies to mammalian cells, and determined the roles of these proteins in endocytosis and cell polarity ...
Uetz P, Rajagopala SV, Dong YA, Haas J (Oct 2004). "From ORFeomes to protein interaction maps in viruses". Genome Research. 14 ... ORFeomes are used for the study of protein-protein interactions, protein microarrays, the study of antigens, and other fields ... "Evolutionarily conserved herpesviral protein interaction networks". PLOS Pathogens. 5 (9): e1000570. doi:10.1371/journal.ppat. ... Titz B, Rajagopala SV, Goll J, Häuser R, McKevitt MT, Palzkill T, Uetz P (2008). Hall N (ed.). "The binary protein interactome ...
Gopinath, S.C.B. (2009). "Mapping of RNA-protein interactions". Analytica Chimica Acta. 636 (2): 117-128. doi:10.1016/j.aca. ... It can thus be used to probe the interactions involved with the secondary structure and other binding interactions of RNA and ...
May 2007). "Epstein-Barr virus and virus human protein interaction maps". Proceedings of the National Academy of Sciences of ... The DNA is surrounded by a protein nucleocapsid, which is surrounded by a tegument made of protein, which in turn is surrounded ... To enter epithelial cells, viral protein BMRF-2 interacts with cellular β1 integrins. Then, viral protein gH/gL interacts with ... The set of proteins and RNAs produced in Latency III transforms the B cell into a proliferating blast (also known as B cell ...
August 2016). "Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function". Molecular Cell. ... has been identified as a protein that specifically binds ETF and this interaction has been indicated to inactivate ETF by ... The native ETF protein contains one molecule of FAD and one molecule of AMP, respectively. First reports on the ETF protein ... This interaction triggers conformational changes and the highly mobile redox active FAD domain of ETF swings to the FAD domain ...
August 2016). "Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function". Molecular Cell. ... has been identified as a protein that specifically binds ETF and this interaction has been indicated to inactivate ETF by ... The native ETF protein contains one molecule of FAD and one molecule of AMP, respectively. First reports on the ETF protein ... This interaction triggers conformational changes and the highly mobile redox active FAD domain of ETF swings to the FAD domain ...
... are commonly used to analyze interactions between proteins. Copurification is one method used to map the interactome of living ... Golemis, Erica (2002). Protein-protein interactions: a molecular cloning manual. Plainview, N.Y: Cold Spring Harbor Laboratory ... to co-purify usually implies that these substances attract each other to form a non-covalent complex such as in a protein ...
"FAM222A protein (human) - STRING interaction network". string-db.org. Retrieved 2020-04-29. "FAM222B family with sequence ... "Gene Detail :: Allen Brain Atlas: Mouse Brain". mouse.brain-map.org. Retrieved 2020-04-29. "GDS4758 / 7958577". www.ncbi.nlm. ... "PHYRE2 Protein Fold Recognition Server". www.sbg.bio.ic.ac.uk. Retrieved 2020-04-29. "I-TASSER server for protein structure and ... The protein appears to be changing very slowly even in distantly related animals. It is changing at a rate just slightly higher ...
"Mapping of interaction domains between human repair proteins ERCC1 and XPF". Nucleic Acids Research. 26 (18): 4146-52. doi: ... XPF provides the endonuclease active site and is involved in DNA binding and additional protein-protein interactions. The ERCC4 ... In the ERCC1-XPF heterodimer, ERCC1 mediates DNA- and protein-protein interactions. ... During NER, the ERCC1 protein interacts with the XPA protein to coordinate DNA and protein binding. Mammalian cells with mutant ...
"Integrative features of the yeast phosphoproteome and protein-protein interaction map". PLOS Computational Biology. 7 (1): ... plays an important role in the regulation of protein-protein interactions in the enzyme. Important in protein degradation. In ... Even if a protein is not phosphorylated itself, its interactions with other proteins may be regulated by phosphorylation of ... Tau protein belongs to a group of Microtubule Associated Proteins (MAPs) which, among several things, help stabilize ...
"High-quality binary protein interaction map of the yeast interactome network". Science. 322 (5898): 104-10. Bibcode:2008Sci... ... Proteins in a protein complex are linked by non-covalent protein-protein interactions. These complexes are a cornerstone of ... Typically, the obligate interactions (protein-protein interactions in an obligate complex) are permanent, whereas non-obligate ... Amoutzias G, Van de Peer Y (2010). "Single-Gene and Whole-Genome Duplications and the Evolution of Protein-Protein Interaction ...
Enright, A. J.; Iliopoulos, I.; Kyrpides, N. C.; Ouzounis, C. A. (1999). "Protein interaction maps for complete genomes based ... Enright, A. J.; van Dongen, S.; Ouzounis, C. A. (2002). "An efficient algorithm for large-scale detection of protein families ... Kyrpides, N.; Overbeek, R.; Ouzounis, C. (1999). "Universal protein families and the functional content of the last universal ... His research interests include genome structure, function and evolution, evolution of protein function, evolution of genetic ...
October 2008). "High-quality binary protein interaction map of the yeast interactome network". Science. 322 (5898): 104-10. ... Schwikowski B, Uetz P, Fields S (December 2000). "A network of protein-protein interactions in yeast". Nature Biotechnology. 18 ... Although most essential genes encode proteins, many essential proteins consist of a single domain. This fact has been used to ... Essential amino acid Essential proteins in protein complexes Gene Genome Minimal genome Mutation Xu, Ping; Ge, Xiuchun; Chen, ...
ISBN 0-8247-0562-9. Pelletier J, Sidhu S (August 2001). "Mapping protein-protein interactions with combinatorial biology ... This could involve the protein being fused to the M13 minor coat protein pIII, with the gene encoding this protein being held ... which are generated and screened by physically linking a gene encoding a protein and a copy of said protein. ... In biotechnology, combinatorial biology is the creation of a large number of compounds (usually proteins or peptides) through ...
Uetz, P. (2004-10-15). "From ORFeomes to Protein Interaction Maps in Viruses". Genome Research. 14 (10b): 2029-2033. doi: ... Protein-fragment complementation assays are often used to detect protein-protein interactions. The yeast two-hybrid assay is ... Pull-down assays are a method to determine what kinds of proteins a protein interacts with. Protein structure prediction can be ... Numerous methods are available to study proteins, sets of proteins, or the whole proteome. In fact, proteins are often studied ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala- ... "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". EMBO ... The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... Yang B, Jung D, Motto D, Meyer J, Koretzky G, Campbell KP (May 1995). "SH3 domain-mediated interaction of dystroglycan and Grb2 ... Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. The dystrophin-glycoprotein complex (DGC) comprises ... a 50-kD transmembrane protein (Roberds et al., 1993).[supplied by OMIM] SGCA has been shown to interact with Biglycan. GRCh38: ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... Inactive ubiquitin carboxyl-terminal hydrolase 53 is a protein that in humans is encoded by the USP53 gene. Although USP53 is ... The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (1): 65-73. ... USP53 localizes at cellular tight junctions and interacts with tight junction protein 2 (TJP2). Mutations in TJP2 have also ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... Nucleoporin 85 (Nup85) is a protein that in humans is encoded by the NUP85 gene. Bidirectional transport of macromolecules ... Doxsey SJ, Stein P, Evans L, Calarco PD, Kirschner M (Feb 1994). "Pericentrin, a highly conserved centrosome protein involved ... "Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis". Nature Immunology. 6 (8): 827-35. doi: ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic". J. Biol. Chem. 270 (22 ... Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic". J. Biol. Chem. 270 (22 ... Syntaxin 3, also known as STX3, is a protein which in humans is encoded by the STX3 gene. The protein encoded by this gene is a ...
July 2020). "A SARS-CoV-2 protein interaction map reveals targets for drug repurposing". Nature. 583 (7816): 459-468. Bibcode: ... The sigma-1 receptor (σ1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that ... σ1R is targeted by the nsp6 protein of SARS-CoV-2 to inhibit autophagosome formation as a process competing with the ... The mammalian σ1 receptor is an integral membrane protein with 223 amino acids. It shows no homology to other mammalian ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... NME1 has been shown to interact with: Aurora A kinase, CD29 NME3, Protein SET, RAR-related orphan receptor alpha, RAR-related ... "Entrez Gene: NME1 non-metastatic cells 1, protein (NM23A) expressed in". Chicco, Davide; Sanavia, Tiziana; Jurman, Giuseppe (4 ... and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement". J. Biol. Chem. 277 (23): 20895- ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... This gene encodes a mitochondrially-localized protein which is classified under the Bcl-2 protein family. Overexpression of the ... An alternatively-spliced protein variant, called Bcl-rambo beta, is composed of only the BH4 domain, completely lacking the BH ... Bcl-rambo is a member of the Bcl-2 family of proteins that regulate apoptosis. In cells, Bcl-rambo is localized to the ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-1178. Bibcode: ... "A protein interaction atlas for the nuclear receptors: properties and quality of a hub-based dimerisation network". BMC Systems ... to nuclear receptors induces a conformation of the receptor that preferentially binds coactivator proteins. These proteins ... Additional proteins including RNA polymerase are then recruited to the NR/DNA complex that transcribe DNA into messenger RNA. ...
"Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... which may be involved both in determining DNA-binding specificity and in mediating protein-protein interactions. Genes in the ... Homeobox protein SIX1 (Sine oculis homeobox homolog 1) is a protein that in humans is encoded by the SIX1 gene. The vertebrate ...
Rajagopala SV, Casjens S, Uetz P (September 2011). "The protein interaction map of bacteriophage lambda". BMC Microbiology. 11 ... Then, protein U is added to the head-proximal end of the tail. Protein Z is able to connect the tail to the head. Protein H is ... which then recruits proteins I, L, K, and G/T to add protein H. Once G and G/T leave the complex, protein V can assemble onto ... O protein binds the ori site, and P protein binds the DnaB subunit of the host replication machinery as well as binding O. This ...