Unlike conventional T cells that recognize protein peptide antigens presented by major histocompatibility complex (MHC) ... Still during the double negative stages, CD34 expression stops and CD1 is expressed. Expression of both CD4 and CD8 makes them ... The other proteins in the complex are the CD3 proteins: CD3εγ and CD3εδ heterodimers and, most important, a CD3ζ homodimer, ... Antigen-naive T cells expand and differentiate into memory and effector T cells after they encounter their cognate antigen ...
Felschow DM, McVeigh ML, Hoehn GT, Civin CI, Fackler MJ (June 2001). "The adapter protein CrkL associates with CD34". Blood. 97 ... a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen ... Crk-like protein is a protein that in humans is encoded by the CRKL gene. v-CRK avian sarcoma virus CT10-homolog-like contains ... Shi CS, Tuscano J, Kehrl JH (February 2000). "Adaptor proteins CRK and CRKL associate with the serine/threonine protein kinase ...
... using the genetic material encoding reprogramming protein factors, recombinant proteins; microRNA, a synthetic, self- ... DC-like antigen-presenting cells obtained from human induced pluripotent stem cells can serve as a source for vaccination ... Red blood cells (RBC)s generated in vitro from mobilized CD34 positive cells have normal survival when transfused into an ... CCAAT/enhancer binding protein-α (C/EBPα) induces transdifferentiation of B cells into macrophages at high efficiencies and ...
... s typically express vimentin, cytokeratins, epithelial membrane antigen, and CD34, whereas they are usually ... Exportin 1 (a.k.a. XPO1 or CRM1) is a nuclear export protein responsible for the export of over 200 proteins, including the ... Two of these inhibitory proteins that have been studied recently are CTLA-4 and PD1, and drugs targeting these proteins are in ... a subclass of protein kinases) is an enzyme that transfers a phosphate group from an ATP molecule to a protein in a cell. It ...
Transmigration of the leukocyte occurs as PECAM proteins, found on the leukocyte and endothelial cell surfaces, interact and ... MadCAM-1 and CD34 as ligands. Suppressed expression of some selectins results in a slower immune response. If L-selectin is not ... and is independent of specific cellular antigens. Cytokines released in the initial immune response induce vasodilation and ... a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade ...
... is a heavily O-glycosylated transmembrane protein that is encoded by the CD99 gene in humans. The protein has a mass of 32 kD. ... Gelin C, Aubrit F, Phalipon A, Raynal B, Cole S, Kaczorek M, Bernard A (1989). "The E2 antigen, a 32 kd glycoprotein involved ... and CD34". J. Cutan. Pathol. 30 (10): 631-6. doi:10.1034/j.1600-0560.2003.00126.x. PMID 14744088. S2CID 37152987. Cerisano V, ... "CD99 monoclonal antibody induce homotypic adhesion of Jurkat cells through protein tyrosine kinase and protein kinase C- ...
The Duffy antigen binding protein in P. vivax is composed of three subdomains and is thought to function as a dimer. The ... Duffy antigen receptor for chemokines, von Willebrand factor, CD31, CD34, CD105 and CD146". J. Pathol. 206 (3): 260-8. doi: ... DARC+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Duffy at BGMUT Blood Group Antigen ... Recent work has identified a number of additional roles for this protein. On erythrocytes, the Duffy antigen acts as a receptor ...
Core histone macro-H2A.1 is a protein that in humans is encoded by the H2AFY gene. Histones are basic nuclear proteins that are ... "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries". International ... "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient ... Takahashi I, Kameoka Y, Hashimoto K (Aug 2002). "MacroH2A1.2 binds the nuclear protein Spop". Biochimica et Biophysica Acta ( ...
CD34 antigen - CD40-ligand - CEA - CEA assay - cecum - cefalexin - cefepime - cefixime - ceftriaxone - celecoxib - celiac ... hu14.18-interleukin-2 fusion protein - Huang Lian - human epidermal growth factor receptor 2 - human leukocyte antigen - human ... antigen - antigen-presenting cell - antigen-presenting cell vaccine - antiglobulin test - antihormone therapy - antimetabolite ... prostate-specific antigen - prostate-specific antigen test - prostatectomy - prostatic acid phosphatase - prostatic ...
Rather, the protein sequence of a humanized antibody is essentially identical to that of a human variant, despite the non-human ... Hou S, Li B, Wang L, Qian W, Zhang D, Hong X, Wang H, Guo Y (July 2008). "Humanization of an anti-CD34 monoclonal antibody by ... segments responsible for the ability of the antibody to bind to its target antigen. Chimeric antibody names contain a -xi- stem ... The latter also have their protein sequences made more similar to human antibodies, but carry a larger stretch of non-human ...
Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a protein that in humans is ... CD164+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CD164 genome location and CD164 ... a novel sialomucin on CD34(+) and erythroid subsets, is located on human chromosome 6q21". Blood. 92 (3): 849-66. doi:10.1182/ ... 1992). "A novel core protein as well as polymorphic epithelial mucin carry peanut agglutinin binding sites in human gastric ...
... the protein-encoding mRNA for the transcriptional regulator Pu.1-protein, elevation of Pu.1 protein predisposes defective IgG1 ... foreign antigens, they compete for antigen recognition and for T cell help, in this fashion of selective pressure those B Cells ... In support of this premise, miR-155-5p was found to be expressed in CD34(+) human HSPCs, and it was speculated that this miRNA ... Immature B cells which are miR-155 deficient evade apoptosis as a result of elevated Bcl-2 protein levels; a protein that was ...
Diagnosis usually involves bone-marrow studies, X-rays, and plasma-protein studies. In dogs, protein studies usually reveal the ... September 2012). "Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells ... a monoclonal antibody against B-cell maturation antigen (BCMA), also known as CD269, indicated for the treatment of adults with ... Asymptomatic/smoldering myeloma: Serum M protein >30 g/L (3 g/dL) or Clonal plasma cells >10% on bone marrow biopsy and No ...
Some research has shown that syncytia formation in betaherpesviruses can vary based on the type of envelop protein expressed by ... Mirandola, P; Secchiero, P; Pierpaoli, S; Visani, G; Zamai, L; Vitale, M; Capitani, S; Zauli, G (2000). "Infection of CD34(+) ... is a specific type of DIHS that may be linked to HHV-7 as the condition may develop in response to herpesvirus antigens. In one ... This information indicates that CXCR4 and CCR5 are not essential receptor proteins for HHV-7 infection. The trademark ...
The protein is a CXC chemokine receptor. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 ... w/w oral fucoidan for 12 days increased the proportion of CD34+CXCR4+ from 45 to 90% and the serum SDF-1 levels, which could be ... "The promiscuous chemokine binding profile of the Duffy antigen/receptor for chemokines is primarily localized to sequences in ... C-X-C chemokine receptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in ...
They found out that the protein synthesis of E.coli was stopped and phage proteins were synthesized. Then, in May 1961, their ... January 2008). "Increased antigen presentation efficiency by coupling antigens to MHC class I trafficking signals". Journal of ... July 1999). "A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from ... Gelinas AD, Davies DR, Janjic N (February 2016). "Embracing proteins: structural themes in aptamer-protein complexes". Current ...
... s do not express CD34 (markers for hematopoietic stem cells, adipose stem cells, VSELs) and CD117 (hematopoietic stem ... This phenomenon was observed by the infusion of green fluorescent protein-labeled naive human Muse cells into animal models ... collected from bone marrow-mesenchymal stem cells as stage-specific embryonic antigen-3 (SSEA-3)+ and -, respectively, or ... and bone morphologic protein-7. Treatment of Muse cells with 5' -azacytidine in suspension culture; then transferring the cells ...
Yu CJ, Shih JY, Lee YC, Shun CT, Yuan A, Yang PC (January 2005). "Sialyl Lewis antigens: association with MUC5AC protein and ... CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant ... matrix protein (M), fusion protein (F), neuraminidase (NA) and large protein (L). All these proteins have variable functions ... F-protein, as other paramyxoviral fusion proteins, is a trimeric class I viral membrane fusion protein. It is produced in the ...