Propranolol
... , sold under the brand name Inderal among others, is a medication of the beta blocker class. It is used to treat ... Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minutes when taken orally. Common ... Propranolol was patented in 1962 and approved for medical use in 1964. It is on the World Health Organization's List of ... Propranolol is available as a generic medication. In 2020, it was the 88th most commonly prescribed medication in the United ...
Prototype drug
Morphine is the prototype of opioid analgesics Propranolol is the prototype of the beta blockers Chlorpromazine is the ... ". "Propranolol". DrugBank. 16 October 2018. Retrieved 16 October 2018. Watanabe, T.; Wada, H. (1991). Histaminergic Neurons ( ...
Thyrotoxic periodic paralysis
Effect of propranolol". The American Journal of Medicine. 57 (4): 584-90. doi:10.1016/0002-9343(74)90010-2. PMID 4432863. (CS1 ... In 1974 it was discovered that propranolol could prevent attacks. The concept of channelopathies and the link with specific ion ... such as propranolol (as most of the symptoms are driven by increased levels of adrenaline and its effect on the β-adrenergic ...
Adrenergic blocking agent
The first beta blocker, propranolol, was introduced in the early 1960s by the winner of The Nobel Prize in Physiology or ... Linde, K.; Rossnagel, K. (2004). Hobson, Anna (ed.). "Propranolol for migraine prophylaxis". The Cochrane Database of ... Phenoxybenzamine Phentolamine Prazosin Tamsulosin Yohimbine Propranolol Timolol Atenolol Metoprolol Butaxamine Still under ...
Dilip Kumar Ganguly
D. K. Ganguly (1976). "Antioxotremorine action of propranolol". British Journal of Pharmacology. 56 (1): 21-24. doi:10.1111/j. ...
Isosorbide mononitrate
Propranolol. The addition of isosorbide mononitrate to propranolol treatment in patients with cirrhosis and portal hypertension ... effect of isosorbide mononitrate was especially evident in patients whose portal pressure was not reduced by propranolol.[ ...
Prevention of migraine attacks
A meta-analysis found that propranolol had an "overall relative risk of response to treatment (here called the 'responder ratio ... 2012). "Randomized, placebo-controlled trial of propranolol added to topiramate in chronic migraine". Neurology. 78 (13): 976- ... "Propranolol for migraine prophylaxis". Cochrane Database Syst Rev (2): CD003225. doi:10.1002/14651858.CD003225.pub2. PMID ... massage and relaxation might be as effective as propranolol or topiramate in the prevention of migraine headaches; however, the ...
Cocaine intoxication
One example is propranolol. Propranolol is a beta blocker that has been approved to treat hypertension, angina, anxiety, and ... Ramoska, Edward; Sacchetti, Alfred D (1985-11-01). "Propranolol-induced hypertension in treatment of cocaine intoxication". ... due to propranolol (n=3), esmolol (n=3), and metoprolol (n=1). Some detractors of beta-blockers for cocaine-induced chest pain ...
List of Scottish inventions and discoveries
Stapleton MP (1997). "Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular ...
Hemangioendothelioma
... response with propranolol and steroids". Clinical Sarcoma Research. 10 (1): 12. doi:10.1186/s13569-020-00134-8. PMC 7394668. ...
James Black (pharmacologist)
The discovery of propranolol was hailed as the greatest breakthrough in the treatment of heart disease since the discovery of ... Propranolol has been described as the greatest breakthrough in heart disease treatments since the 18th century discovery of ... His invention of propranolol, the beta adrenergic receptor antagonist that revolutionised the medical management of angina ... He went to work for ICI Pharmaceuticals in 1958 and, while there, developed propranolol, a beta blocker used for the treatment ...
Pronethalol
Stapleton MP (1997). "Sir James Black and propranolol. The role of the basic sciences in the history of cardiovascular ... and was superseded by propranolol from 1965 onward. Beta blocker Discovery and development of beta-blockers Quirke V (January ...
1962 in science
James W. Black synthesises propranolol, the first beta blocker (used for regulation of angina pectoris), which becomes the ... 122-4. ISBN 978-3-540-19587-0. Stapleton, Melanie P. (1997). "Sir James Black and Propranolol". Texas Heart Institute Journal. ...
Akathisia
Benzodiazepines, such as lorazepam; beta blockers such as propranolol; anticholinergics such as benztropine; and serotonin ... particularly propranolol. The term was first used by Czech neuropsychiatrist Ladislav Haškovec, who described the phenomenon in ... "Cyproheptadine versus propranolol for the treatment of acute neuroleptic-induced akathisia: a comparative double-blind study". ...
Beta blocker
... propranolol Propranolol is the only agent indicated for the control of tremor, portal hypertension, and esophageal variceal ... Elman MJ, Sugar J, Fiscella R, Deutsch TA, Noth J, Nyberg M, Packo K, Anderson RJ (1998). "The effect of propranolol versus ... Discusses the use of propranolol by a North Korean pistol shooter in the 2008 Olympics) beta-Adrenergic+Blockers at the U.S. ... "Propranolol hydrochloride" (PDF). Retrieved September 3, 2020. National Heart, Lung, and Blood Institute (2007). "Expert Panel ...
List of psychotropic medications
Inderal (propranolol) - a beta blocker; it is used for acute anxiety, panic attacks, hypertension. Intuniv (Guanfacine) - A ...
Adrenergic storm
... alprazolam and propranolol; alprazolam weakly agonizes dopamine receptors and causes catecholamine release while propranolol ...
Bupranolol
Its potency is similar to propranolol. Like other beta blockers, oral bupranolol can be used to treat hypertension and ...
Adrenergic urticaria
Treatment involves propranolol and trigger avoidance. Aquagenic urticaria Urticaria Skin lesion List of cutaneous conditions ...
Adrenergic antagonist
Propranolol is a β-adrenoreceptor antagonist. While competitive antagonists bind to the agonist or ligand binding site of the ... Phentolamine phenoxybenzamine Tamsulosin Propranolol Nebivilol Atenolol Oxprenolol Metoprolol Timolol Pindolol Nadolol Pindolol ... Adrenergic receptor Alpha blocker Beta blocker List of adrenergic drugs Propranolol Sympathetic nervous system Wiysonge, CS; ... Two examples of competitive adrenergic antagonists are propranolol and phentolamine. Phentolamine is a competitive and ...
Performance-enhancing substance
Diazepam, nicotine, and propranolol are common examples. Ethanol, the most commonly used substance by athletes, can be used for ...
Anxiolytic
Propranolol is originally used for heart diseases. It can also be used to treat anxiety with symptoms like tremor or increased ... Beta blockers include propranolol, oxprenolol, and metoprolol. The alpha-1 agonist prazosin could be effective for PTSD. The ...
Infantile hemangioma
Oral propranolol is more effective than placebo, observation without intervention, or oral corticosteroids. Propranolol has ... 2008). "Propranolol for severe hemangiomas of infancy". N Engl J Med. 358 (24): 2649-51. doi:10.1056/nejmc0708819. PMID ... Certain cases, however, may result in problems and the use of medication such as propranolol or steroids are recommended. ... 2015). "A randomized, controlled trial of oral propranolol in infantile hemangioma". N Engl J Med. 372 (8): 735-46. doi:10.1056 ...
Priapism
Anticoagulants (heparin and warfarin). Antihypertensives (i.e., hydralazine, guanethidine and propranolol). Hormones (i.e., ...
Polythiazide
O'Brien ET, MacKinnon J (October 1972). "Propranolol and polythiazide in treatment of hypertension". British Heart Journal. 34 ...
Neuroethics
Propranolol, an FDA-approved drug, has been suggested to effectively dull the painful effects of traumatic memories if taken ... Originally, propranolol was reserved for hypertension patients. However, doctors are permitted to use the drug for off-label ... Elsey, James; Kindt, Merel (June 2018). "Can criminals use propranolol to erase crime-related memories? A response to McGorrery ...
Hemangioma
Oral beta blockers such as propranolol or atenolol have been used since 2008 and are the first-line treatment of hemangiomas. ... "What is the role of propranolol in the treatment of infantile hemangiomas?". Nguyen, Harrison P.; Pickrell, Brent B.; Wright, ... Zhang, Ling; Wu, Hai-Wei; Yuan, Weien; Zheng, Jia-Wei (2017-05-08). "Propranolol therapy for infantile hemangioma: our ... PMID 30790601 . Ge, Jing; Zheng, Jiawei; Zhang, Ling; Yuan, Weien; Zhao, Haiguang (2016-01-28). "Oral propranolol combined with ...
Primary polydipsia
"Compulsive water drinking treated with high dose propranolol". The Journal of Nervous and Mental Disease. 168 (4): 246-248. doi ... an angiotensin II receptor antagonist Propranolol, a sympatholytic beta blocker Vasopressin receptor antagonists, such as ...
Hematidrosis
... propranolol 10 mg) with significant reduction in the frequency of spontaneous blood oozing. The successful use of beta blockers ... "A Case of Hematidrosis Successfully Treated with Propranolol". American Journal of Clinical Dermatology. 11 (6): 440-43. doi: ...
Migraine treatment
Due to the high penetration across the blood-brain barrier, lipophilic beta blockers, such as propranolol and metoprolol, are ... 1966). "The prophylactic value of propranolol in angina pectoris". Am J Cardiol. 18 (3): 370-83. doi:10.1016/0002-9149(66)90056 ... The beta-blockers that are used in migraine treatment are propranolol, nadolol, timolol, metoprolol, and atenolol. Adverse drug ...