Loading...
*  Plasmid partition system
The centromere like site, parC contains two sets of five 11 base pair direct repeats separated by the parMR promoter. The amino ... The mechanism is similar to a treadmill mechanism: Multiple TubR dimer binds to the centromere-like region stbDRs of the ... Guynet C, de la Cruz F (2011). "Plasmid segregation without partition". Mobile Genetic Elements. 1 (3): 236-241. doi:10.4161/ ... region surrounding the plasmid The plasmid then chases the resulting ParA gradient on the perimeter of the ParA depleted region ...
*  KCNA3
A genetic variation in the Kv1.3 promoter region is associated with low insulin sensitivity and impaired glucose tolerance. ... "Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins". Neuron. 15 (5): 1169-81 ... "A family of three mouse potassium channel genes with intronless coding regions". Science. 247 (4945): 973-5. doi:10.1126/ ...
*  Tpr-met fusion protein
The genomic rearrangement fuses two genetic loci,translocated promoter region, from chromosome 1q25 which encodes a ...
*  Genetic engineering techniques
These genetic elements are generally a promoter and terminator region as well as a selectable marker gene. This vector is then ... The promoter region initiates transcription of the gene and can be used to control the location and level of gene expression, ... As well as the gene to be inserted most constructs contain a promoter and terminator region as well as a selectable marker gene ... another method to deliver genetic modifications to plants List of genetic engineering software: software to code the genetic ...
*  Genetic engineering
These include a promoter and terminator region, which initiate and end transcription. A selectable marker gene is added, which ... Genetic engineering is a process that alters the genetic make-up of an organism by either removing or introducing DNA. Unlike ... If genetic engineering is used to remove genetic material from the target organism the resulting organism is termed a knockout ... If genetic material from another species is added to the host, the resulting organism is called transgenic. If genetic material ...
*  Gilbert's syndrome
UGT1A1 is associated with a TATA box promoter region; this region most commonly contains the genetic sequence A(TA6)TAA; this ... the most common of which results from adding another dinucleotide repeat TA to the promoter region, resulting in A(TA7)TAA, ... most commonly due to a polymorphism in the promoter region of the UGT1A1 gene". Journal of Hepatology. 33 (3): 348-351. doi: ... "Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome". Lancet. 347 (9001): 578-81. ...
*  Survivin
With regard to genetic analysis of the survivin promoter region, the isolated DNA of AML and PBMCs were treated with bisulfite ... and the survivin promoter region sequence was amplified out with PCR and sequenced to look for any particular genetic changes ... they did both an epigenetic and a genetic analysis of the survivin gene promoter region in AML patients and compared the ... This result suggests that the occurrence of these SNPs in the promoter region of the survivin gene also appears to be of no ...
*  Golden Gate Cloning
Level 0 modules are the base for MoClo system, where they contain genetic elements like a promoter, a 5' untranslated region ( ... First-tier Golden Gate assembly constructs the single-gene construct by adding in genetic elements such as promoter, open ... In this process, one needs to make sure that the introduced mutation will not affect the genetic function encoded by the ... An Iterative Cloning System for Standardized Assembly of Reusable Genetic Modules". PLOS ONE. 6 (7): e21622. doi:10.1371/ ...
*  Chlorpyrifos
Human populations have genetic variation in the sequence of PON1 and its promoter region that may influence the effectiveness ... as a genetic determinant of susceptibility to organophosphate toxicity". Toxicology. Emerging health issues from chronic ... CALIFORNIA REGIONAL WATER QUALITY CONTROL BOARD CENTRAL COAST REGION. p. 65. Chlorpyrifos General Fact Sheet (pdf version - ...
*  Sucrose phosphorylase
The complex binds to the promoter region to activate transcription, enhancing the creation of sucrose phosphorylase (Nelson and ... "Sucrose utilization in bacteria: genetic organization and regulation." Journal of Applied Microbiology & Biotechnology 67.3 ( ... Cox 2005). Genetic regulation of sucrose phosphorylase is also performed by metabolites. Through experimentation it is known ...
*  Shyness
Several genetic links to shyness are current areas of research. One is the serotonin transporter promoter region polymorphism ( ... Scientists believe that they have located genetic data supporting the hypothesis that shyness is, at least, partially genetic. ... "Relation of shyness in grade school children to the genotype for the long form of the serotonin transporter promoter region ... The long version of the 5-HTT gene-linked polymorphic region (5-HTTLPR) is now postulated to be correlated with shyness, but in ...
*  Transgenerational stress inheritance
Stress can also result in inheritable changes DNA methylation in the promoter regions of the estrogen receptor alpha (ERĪ±), ... Small non-coding RNAs may serve as a potential mechanism for stress-related genetic changes in offspring. Mouse models of ... These heritable epigenetic modifications include DNA methylation of the promoter regions of genes that affect sensitivity to ... Evidence of decreased complexity in the CA1 and CA3 region of the hippocampus in terms of dendritic length and spine density ...
*  FAM149A
In addition, the Isoelectric Point of FAM149A is 9.891999 The following is an analysis of the promoter region for FAM149A. It ... shows a number of transcription factor binding sites that may have strong contribution to regulating the genetic expression. ... Here is the promoter for the FAM149A gene provided by ElDorado and the sequence extracted from the information. The following ... Only the dog contains what is considered as an Evolutionary Conserved Region (ECR). Based on the graphs on the right, the ...
*  Vesicular monoamine transporter
Specifically, the SLC18A2 promoter region for the VMAT2 gene has been identified as an area where several polymorphisms form ... Studies using a genetic rodent model to understand clinical depression in humans suggest that VMAT2 genetic or functional ... Genetic research models have shown that polymorphisms in SLC18A1 and SLC18A2, the genes that encode for VMAT1 and 2 proteins ... VMAT gene sequence analysis demonstrates that 4 aspartic acid residues in the middle region of TMD I, VI, X, and XI and one ...
*  Ageing
... methylation of gene promoter regions or alterations of the DNA scaffolding which regulate gene expression), can cause abnormal ... Most known genetic interventions in C. elegans increase lifespan by 1.5 to 2.5-fold. As of 2009[update], the record for ... Genetic instability: In heart muscle cells, dogs annually lose approximately 3.3% of the DNA in their heart muscle cells while ... Such a genetic effect is called the antagonistic pleiotropy effect when referring to a gene (pleiotropy signifying the gene has ...
*  Molecular drive
To date all regulatory regions (promoters) and genes, that have been examined in detail at the molecular level, have TRAM ... According to Dover, TRAM is a genetic system that has features of Non-mendelian inheritance Turnover, copy number and ... Molecular drive is a term coined by Gabriel Dover in 1982 to describe evolutionary processes that change the genetic ... Molecular drive operates independently of natural selection and genetic drift. The best-known such process is the concerted ...
*  Z-DNA
A study of human chromosome 22 showed a correlation between Z-DNA forming regions and promoter regions for nuclear factor-I. ... Both of these genetic modifications have been linked to the gene translocations found in cancers such as leukemia and lymphoma ... Z-DNA sequences downstream of promoter regions have been shown to stimulate transcription. The greatest increase in activity is ... A study on Escherichia coli found that gene deletions spontaneously occur in plasmid regions containing Z-DNA-forming sequences ...
*  ENO3
TFG-TEC binds to the proximal promoter region of the ENO3 gene. Click on genes, proteins and metabolites below to link to ... Advances in genetic testing, such as exome sequencing and specific gene panels, can provide greater access to diagnoses for ... The ENO3 gene spans 6 kb and contains 12 exons, though the first exon is an untranslated region and, thus, non-coding. This ... Upstream of the first exon lies a TATA-like box and CpG-rich region, which contains recognition motifs for binding ...
*  Somatic evolution in cancer
Cytogenetic studies localized the region to the long arm of chromosome 13, and molecular genetic studies demonstrated that ... while in most cases the loss is due to methylation of its promoter region. Similarly, when loss of expression of the DNA repair ... This theory predicts a unique genetic composition in each neoplasm due to the random process of mutations, genetic ... These genetic changes can be grouped into six "hallmarks", which drive a population of normal cells to become a cancer. The six ...
*  Marco Antonio Zago
... including a point mutation in the promoter region of the gamma globin gene responsible for the Brazilian form of HbF ... Genetic control of F-cells in human adults. Blood. vol. 53, p. 977-986. ZAGO, M. A. and BOTTURA, C. 1983. Splenic function in ... Identified for the first time in the country and described the genetic, the biochemical and the clinical features of several ... Studied the contribution of genetic factors to the origin of thrombosis, including the role of mutations of several genes, ...
*  Mir-433
The 3' coding region of mir-433 is also the promoter of the neighbouring miRNA gene: mir-127. The two genes overlap and are ... This is a method by which genetic information can be stored in a compact and efficient way. Mir-433, along with the other ... No such association was found between mir-433 variation and Parkinson's disease despite the fact that variation in the region ... A single nucleotide polymorphism (SNP) in the 3' untranslated region (UTR) of HDAC6 was found to segregate with the ...
*  Cis-regulatory element
Promoters are relatively short sequences of DNA which include the site where transcription is initiated and the region ... The most efficient way for an organism to regulate genetic expression is at the transcriptional level. CREs function to control ... The most well characterized types of CREs are enhancers and promoters. Both of these sequence elements are structural regions ... must bind sequentially to this region. Only once this region has been bound with the appropriate set of TFs, and in the proper ...
*  Epithelial cell adhesion molecule
... end of the EpCAM gene causes epigenetic inactivation of the MSH2 gene by hypermethylating the promoter region of the MSH2 gene ... A problem in EpCAM can indirectly cause Lynch syndrome, a genetic disorder that leads to increased risk of cancer. Deletion of ... Tomita, N; Yamano T; Matsubara N; Tamura K (2013). "[A Novel Genetic Disorder of Lynch Syndrome-EPCAM Gene Deletion]". Gan to ...
*  SNP annotation
Genetic variants that located in distal regulatory region can affect the binding motif of TFs, chromatin regulators and other ... The non-coding region of genome contain many important regulatory elements including promoter, enhancer and insulator, any kind ... Li, M.J.; Yan, B.; Sham, P.C.; Wang, J. (2014). "Exploring the function of genetic variants in the non-coding genomic regions: ... SNPs are the most common genetic variant found in all individual with one SNP every 100-300 bp in some species. Since there is ...
*  DNA vaccination
The SV40 promoter was conventionally used until research showed that vectors driven by the Rous Sarcoma Virus (RSV) promoter ... These "genetic adjuvants" can be administered as a: mixture of 2 plasmids, one encoding the immunogen and the other encoding ... Accessory regions pertaining to the plasmid backbone may engage in a wide range of structural instability phenomena. Well-known ... The advantages of genetic adjuvants are their low cost and simple administration, as well as avoidance of unstable recombinant ...
*  Southern Leyte
In recent years there has been a drive to promote tourism in the region. There is a new Zoo and Wildlife Park in Brgy. Danao in ... There was also established in Maasin a Court of First Instance, then known as the Promoter Fiscal, where all minor ... Felix, Rocel C. (7 April 2006). "Genetic Engineering Eyed to Solve Problems of Abaca Industry". NewsFlash.org. STAR. Archived ... "Region VIII; Leyte--Northern Samar". Living in the Philippines. Archived from the original on 4 May 2003. Retrieved 28 July ...
*  Noncoding DNA
A promoter is a region of DNA that facilitates transcription of a particular gene when a transcription factor binds to it. ... Promoters are typically located near the genes they regulate and upstream of them. A genetic insulator is a boundary element ... Ultimately genetic, evolutionary, and biochemical approaches can all be used in a complementary way to identify regions that ... Promoters facilitate the transcription of a particular gene and are typically upstream of the coding region. Enhancer sequences ...