Dendritic cells are derived from hematopoietic bone marrow progenitor cells (HSC). These progenitor cells initially transform ... and bone marrow and evidence (i.e. cytopenias) of bone marrow failure. Blastic plasmacytoid dendritic cell neoplasm has a high ... The monocytes in turn are formed from stem cells in the bone marrow. Monocyte-derived dendritic cells can be generated in vitro ... Mo-DC or MDDC refers to cells matured from monocytes. HP-DC refers to cells derived from hematopoietic progenitor cells. ...
It suppresses the bone marrow by inhibiting the erythroid progenitor cells. Anti-M also recommends antigen testing to rule out ... which will usually be increased as the bone marrow makes new red blood cells to replace the ones that are being destroyed, and ... Vaughan JI, Manning M, Warwick RM, Letsky EA, Murray NA, Roberts IA (March 1998). "Inhibition of erythroid progenitor cells by ... It works by binding any fetal red blood cells with the D antigen before the mother is able to produce an immune response and ...
"Differential mobilization of subsets of progenitor cells from the bone marrow". Cell Stem Cell. 4 (1): 62-72. doi:10.1016/j. ... In this model, the cancer cells that survived radiation critically depended on bone marrow derived cells for vasculogenesis, ... are important in hematopoietic stem cell homing to the bone marrow and in hematopoietic stem cell quiescence. The in vivo ... Plerixafor has been found to be a strong inducer of mobilization of hematopoietic stem cells from the bone marrow to the ...
Anti-Kell suppresses the bone marrow, by inhibiting the erythroid progenitor cells. anti-Kell2, anti-Kell3 and anti-Kell4 ... "Inhibition of Erythroid Progenitor Cells by Anti-Kell Antibodies in Fetal Alloimmune Anemia". New England Journal of Medicine. ... Cell-free DNA, Amniocentesis, and Chorionic Villus Sampling (CVS). Of the three, CVS is no longer used due to risk of worsening ... Fetal antigen status can be tested as early as 15 weeks by PCR of fetal cells. CVS is possible as well to test fetal antigen ...
"Expression of glypican-4 in haematopoietic-progenitor and bone-marrow-stromal cells". The Biochemical Journal. 344. 344 Pt 3 (3 ... "Cell surface glypicans are low-affinity endostatin receptors" (PDF). Molecular Cell. 7 (4): 811-22. doi:10.1016/S1097-2765(01) ... These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end ... Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable ...
... that originate from bone marrow. HSCs first differentiate into multipotent progenitor (MPP) cells, then common lymphoid ... B-2 cell FO B cells and MZ B cells. Follicular (FO) B cell (also known as a B-2 cell) Most common type of B cell and, when not ... migrate to bone marrow. Antigens that activate B cells without T cell help are known as T cell-independent (TI) antigens and ... "Long-lived bone marrow plasma cells are induced early in response to T cell-independent or T cell-dependent antigens". Journal ...
September 2012). "Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells ... bone marrow biopsy finding cancerous plasma cells, and medical imaging finding bone lesions. Another common finding is high ... The plasma cells can also form a mass in the bone marrow or soft tissue. When one tumor is present, it is called a plasmacytoma ... "Getting a Stem Cell or Bone Marrow Transplant". American Cancer Society. Archived from the original on 10 June 2023. Retrieved ...
"Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells". Blood. 101 (3): 877-85. ... "The alpha4 laminin subunit regulates endothelial cell survival". Experimental Cell Research. 294 (1): 281-9. doi:10.1016/j. ... Mrowiec T, Melchar C, Górski A (1998). "HIV-protein-mediated alterations in T cell interactions with the extracellular matrix ... They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, ...
Cellular factors include reduced number and function of bone-marrow derived endothelial progenitor cells. and reduced ability ... Sinusoids are irregular spaces filled with blood and are mainly found in the liver, bone marrow, spleen, and brain ... bone marrow, anterior pituitary gland, and brain circumventricular organs. Capillaries and sinusoids are short vessels that ... "Circulating Humoral Factors and Endothelial Progenitor Cells in Patients with Differing Coronary Collateral Support" (PDF). ...
Bone marrow stromal cells found in the epidermis and make up 10% of progenitor cells. They are often classed as stem cells due ... A progenitor cell is a biological cell that can differentiate into a specific cell type. Stem cells and progenitor cells have ... However, stem cells are less specified than progenitor cells. Progenitor cells can only differentiate into their "target" cell ... Before embryonic day 40 (E40), progenitor cells generate other progenitor cells; after that period, progenitor cells produce ...
2007). "Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization". Genes & ... Ablation of the endothelial progenitor cells in the bone marrow lead to a significant decrease in tumour growth and vasculature ... Recently, controversy has developed over the definition of true endothelial progenitors. Although bone marrow-derived cells do ... Inhibitor of DNA Binding 1 (ID1) has been used as a marker for these cells; this allows for tracking EPCs from the bone marrow ...
"In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow". Nature Protocols. 6 (1 ... Multiphoton microscopy also allows visualizing cells located underneath bone tissues such as cells of the bone marrow. The ... "T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments". Nature. 538 (7626): 518-522. doi: ... Cells need to produce a fluorescent protein to be visualized and this can be achieved by introducing a transgene. Intravital ...
When expressed in Bone Marrow CD34+ progenitor cells, BAALC has neuroectodermal and hematopoietic cell functions. ... BAALC expression has only been found in Bone Marrow (BM) when expressed from CD34+ progenitor cells, besides this BAALC ... The expression of BAALC from the CD34+ progenitor cells suggest the gene has neuroectodermal and hematopoietic cell functions. ... BAALC is seen in acute leukemia in immature myoblasts and early progenitor cells, but is excluded from mature hematopoietic ...
... and reacts with immature cells in normal bone marrow". Leukemia Research. 9 (1): 1-9. doi:10.1016/0145-2126(85)90016-5. PMID ... Multipotent progenitor cells (MPPs): CD150−CD48−CD244+ Lineage-restricted progenitor cells (LRPs): CD150−CD48+CD244+ Common ... and thus partial overlap with the stem cell populations and sometimes other closely related cells that are not stem cells. Also ... Loken MR, Shah VO, Civin CI (1987). "Characterization of myeloid antigens on human bone marrow using multicolour ...
Normal LSEC turnover is maintained by the liver resident population of LSEC progenitor cells; in addition, recruitment of bone ... marrow derived cells contributes to replenish the LSEC population when needed. By the end of the 19th and beginning of the 20th ... The name scavenger endothelial cells (SECs) has been coined to denote the endothelial cells in vertebrates that are geared to ... these specialized endothelial cells are located either in the heart endocardium or in endothelial cells of the kidney ...
Osteochondroprogenitor cells are progenitor cells that arise from mesenchymal stem cells (MSC) in the bone marrow. They have ... before any genetic or morphological criteria were put in place for bone marrow or connective tissues. Osteoprogenitor cells can ... giving rise to either bone or cartilage respectively. Osteochondroprogenitor cells are important for bone formation and ... Osteoblasts are cells that group together to form units, called osteons, to produce bone. Runx2 (which may also be known as ...
"Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice". ... May 2003). "Differentiation of bone marrow cells into cells that express liver-specific genes in vitro: implication of the ... 2005). "Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors". Stem Cells. 23 (6 ... "Nucleostemin is a marker of proliferating stromal stem cells in adult human bone marrow". Stem Cells. 24 (4): 1113-20. doi: ...
... and dendritic cells arise from a common bone marrow progenitor cell subset". Immunity. 3 (4): 459-73. doi:10.1016/1074-7613(95) ... Some benign T cells can be CD10+ Clear cell renal cell carcinoma (Clear cell RCC) CD10+ distinguishes renal cell carcinoma, ... Follicular lymphoma (follicle centre cell lymphoma) are CD10+. Burkitt Lymphoma cells are CD10+. CD10+ diffuse large B cell ... diffuse large B-cell lymphoma (variable), follicular center cells (70%), hairy cell leukemia (10%), and myeloma (some). It ...
"P-Selectin coated microtube for enrichment of CD34+ hematopoietic stem and progenitor cells from human bone marrow". Clinical ... Cell bank Human genome Meristem Mesenchymal stem cell Ovarian stem cell Partial cloning Plant stem cell Stem cell controversy ... muscle and fat cells. Adult stem cells are a small minority of cells; they are vastly outnumbered by the progenitor cells and ... Stem cell therapy is the use of stem cells to treat or prevent a disease or condition. Bone marrow transplant is a form of stem ...
The drug stimulates erythropoiesis by interacting with the erythropoietin receptor on progenitor cells in the bone marrow. It ...
"Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches". Nature. 495 (7440): 231-235. ... cells include skeletal stem cells that are a major source of new bone cells and adipocytes that form in adult bone marrow. The ... "Leptin Receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow". Cell Stem ... "SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells". Cell. ...
Most of the blood cells produced in the bone marrow during hematopoiesis come from megakaryocyte/erythrocyte progenitor cells. ... which occurs in the bone marrow. Hematopoietic stem cells can differentiate into one of two progenitor cells: the common ... Megakaryocyte-erythroid progenitor cells, among other blood cells, are generated as a result of hematopoiesis, ... MEPs derive from the common myeloid progenitor lineage. Megakaryocyte/erythrocyte progenitor cells must commit to becoming ...
... developments in mobilization of hematopoietic stem and progenitor cells and their interaction with nicehes in bone marrow". ... Besides liver cells, A1PI is produced in bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth ... "Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization ... In addition to binding to neutrophil elastase released by inflammatory cells, A1AT also binds to elastase localized on the cell ...
... progenitor cells from human bone marrow". Blood. 95 (2): 510-8. doi:10.1182/blood.V95.2.510. PMID 10627456. Koivunen J, ... researchers understand that PKC-α is correlated with the differentiation of erythroid progenitor cells in bone marrow. These ... This prevents foreign molecules from entering the cell and helps regulate the internal environment of the cell. Cells infected ... cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a ...
"Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells". The Journal of ... He has authored the books Bioseparations, Cell Culture Technology for Pharmaceutical and Cell-Based Therapies and Cell Culture ... In addition to his work with Chinese hamster ovary cells, his work has enabled the use of process engineering for cell therapy ... and to promote post-genomic research in cell bioprocessing. His research focuses on the field of cell culture bioprocessing, ...
"Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand". Cell. 109 ( ... monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, ... bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, ... For example, its increased expression was seen in a metastatic mammary cancer cell line. Gelatinase B plays a central role in ...
"Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand". Cell. 109 ( ... For example, its increased expression was seen in a metastatic mammary cancer cell line. A.R. Farina and others have argued ... Lastly, there is significant evidence that Gelatinase B is required for the recruitment of endothelial stem cells, a critical ... Cell. 93 (3): 411-22. doi:10.1016/s0092-8674(00)81169-1. PMC 2839071. PMID 9590175. Heissig B, Hattori K, Dias S, Friedrich M, ...
... on bone marrow hematopoietic stem cell/progenitor cell in vitro". Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi. 23 (6 ... Studies conducted in freshly isolated cells, cultured cells, animals, and tissue samples indicate that CKLF1 is a chemokine- ... cells may contribute to the maturation of various tissues such as blood cells and skeletal muscle from their precursor cells ... dendritic cells, and perhaps other CCR4-receptor bearing cells. Preliminary findings suggest that the actions of CKLF1 on these ...
"Differential expression of cell adhesion molecules by human hematopoietic progenitor cells from bone marrow and mobilized adult ... "Distribution of cell adhesion molecules on CD56++, CD3-, CD16- large granular lymphocytes and endothelial cells in first- ... Chirmule N, Oyaizu N, Saxinger C, Pahwa S (1994). "Nef protein of HIV-1 has B-cell stimulatory activity". AIDS. 8 (6): 733-4. ... CD11a+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ITGAL Info with links in the Cell ...
B cells and T cells are produced by stem cells in the bone marrow. T cell progenitors then migrate from the bone marrow to the ... Gamma delta T cells (γδ T cells) possess an alternative T cell receptor (TCR) as opposed to CD4+ and CD8+ αβ T cells and share ... When B cells and T cells are activated some become memory B cells and some memory T cells. Throughout the lifetime of an animal ... The cells that carry out the adaptive immune response are white blood cells known as lymphocytes. B cells and T cells, two ...