... poliovirus. DNA encoding the RNA genome of poliovirus was introduced into cultured mammalian cells and infectious poliovirus ... There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The ... Poliovirus infects human cells by binding to an immunoglobulin-like receptor, CD155 (also known as the poliovirus receptor or ... Drake demonstrated that poliovirus is able to undergo multiplicity reactivation. That is, when polioviruses were irradiated ...

"Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor". Science. 280 (5369): ... Poliovirus receptor-related 1 (PVRL1), also known as nectin-1 and CD111 (formerly herpesvirus entry mediator C, HVEC) is a ... "Entrez Gene: PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin)". Cocchi F, Lopez M, Menotti L, Aoubala ... "The Ectodomain of a Novel Member of the Immunoglobulin Subfamily Related to the Poliovirus Receptor Has the Attributes of a ...

... (PVRL2), also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), is a ... "Entrez Gene: PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)". Eberlé F, Dubreuil P, Mattei MG, et al. (1995 ... 2002). "The poliovirus receptor related 2 (PRR2) and apolipoprotein E genes and coronary heart disease". Journal of ... 1999). "The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule". Blood ...

Efforts were built upon those used to control wild poliovirus in the Americas in the early 1980s, and on lessons from smallpox ... In 1995 the Global Certification Commission was created to oversee the certification of the eradication of wild-type poliovirus ... ". "Africa eradicates wild poliovirus". October 10, 2023. "Data Monitoring". Global Polio Eradication Initiative. Retrieved ...

"Global Wild Poliovirus 2015 -2020" (PDF). "Global Wild Poliovirus 2016-2021" (PDF). GPEI. 4 January 2022. Retrieved 16 January ... "Africa eradicates wild poliovirus". WHO Regional Office for Africa. Branswell H (8 June 2017). "Polio outbreak is reported in ... "Wild Poliovirus 2008 - 2013" (PDF). Global Polio Eradication Initiative. Archived from the original (PDF) on 18 May 2013. ... There have been no cases caused by wild strains of poliovirus in Nigeria since August 2016, though cVDPV2 was detected in ...

Wild poliovirus type 1 is the only type of wild poliovirus that remains uninterrupted globally. The GCC held its 21st meeting ... The GCC certified the worldwide eradication of indigenous wild poliovirus type 2 on 20 September 2015, and wild poliovirus type ... "The poliovirus transmission in Lao People's Democratic Republic has ceased" (Press release). World Health Organization (WHO). 6 ... The GCC certified the global eradication of wild poliovirus type 2 (WPV2) at its 14th meeting on 20 September 2015. which led ...

"Africa eradicates wild poliovirus". WHO. August 25, 2020. Retrieved August 25, 2020. "Jeff Bezos Becomes The First Person Ever ...

Nigeria had become a net exporter of the poliovirus to its African neighbors. People in the northern states were also reported ... "Wild poliovirus 2000-2008" (PDF). Global Polio Eradication Initiative. February 5, 2008. Archived from the original (PDF) on ... poliovirus, smallpox, tetanus, diphtheria, typhoid, typhus, and yellow fever. However, the diseases mainly prevalent in Vietnam ... Cutter Laboratories produced 120,000 doses of the Salk polio vaccine that inadvertently contained some live poliovirus along ...

"South Sudan eradicates wild poliovirus". www.unicef.org. Retrieved 2022-10-18. AfricaNews (2022-03-24). "South Sudan leader ... free of wild polio virus. She was sacked by a presidential decree of Salva Kiir Mayardit after being appointed to the position ...

List of disasters in New York City by death toll Melnick J (July 1, 1996). "Current status of poliovirus infections". Clin ...

"Technology for cultivating polio virus". The Lasker Foundation. Retrieved 13 February 2021. "Enders, John F. (1897-1985) , ... Jonas Salk applied the Enders-Weller-Robbins technique to produce large quantities of poliovirus, and then developed a polio ... and Frederick Chapman Robbins reported successful in vitro culture of an animal virus-poliovirus. The three received the 1954 ...

"Wild poliovirus 2000-2008" (PDF). Global Polio Eradication Initiative. 2008-02-05. Archived from the original (PDF) on 2007-09- ...

Melnick, Joseph L. (July 1, 1996). "Current status of poliovirus infections". Clinical Microbiology Reviews. 9 (3): 293-300. ...

Active poliovirus baked from scratch". Science. 297 (5579): 174-5. doi:10.1126/science.297.5579.174b. PMID 12114601. S2CID ... In 2002, researchers at Stony Brook University succeeded in synthesizing the 7741 bp poliovirus genome from its published ...

The Salk vaccine, or inactivated poliovirus vaccine (IPV), consists of an injected dose of killed poliovirus. In 1954, the ... Exposure to poliovirus was therefore delayed until late childhood or adult life, when it was more likely to take the paralytic ... The last cases of paralytic poliomyelitis caused by endemic transmission of poliovirus in the United States were in 1979, when ... CBC Digital Archives - Polio: Combating the Crippler-Video and radio reports related to polio Poliovirus in New Zealand 1915- ...

The attenuated poliovirus in the Sabin vaccine replicates very efficiently in the gut, the primary site of wild poliovirus ... Three serotypes of poliovirus have been identified - wild poliovirus type 1 (WPV1), type 2 (WPV2), and type 3 (WPV3) - each ... Rarely, it may be possible to identify poliovirus in the blood or in the cerebrospinal fluid. Poliovirus samples are further ... The Salk vaccine, or inactivated poliovirus vaccine (IPV), is based on poliovirus grown in a type of monkey kidney tissue ...

Lundquist RE, Sullivan M, Maizel JV (November 1979). "Characterization of a new isolate of poliovirus defective interfering ... "Nonreplicative RNA recombination in poliovirus". Journal of Virology. 73 (11): 8958-8965. doi:10.1128/JVI.73.11.8958-8965.1999 ... can occur within nearly every class of both DNA and RNA viruses both in clinical and laboratory settings including poliovirus, ...

"Polio Vaccine: Vaccine-Derived Poliovirus , CDC". 25 March 2021. "Vaccines: Breaking down and debunking 10 myths". USA Today. ... reversion mutations that reactivate the virus can give rise to disease-causing circulating vaccine-derived poliovirus (cVDPV) ...

Melnick, Joseph L. (1996-07-01). "Current Status of Poliovirus Infections" (PDF). Clinical Microbiology Reviews. American ...

Ouzilou L, Caliot E, Pelletier I, Prévost MC, Pringault E, Colbère-Garapin F (September 2002). "Poliovirus transcytosis through ...

Pollack, Andrew (July 12, 2002). "Traces of Terror: The Science; Scientists Create a Live Polio Virus". The New York Times. ...

Yogo, Y; Wimmer, Eckard (1972). "Sequence studies of Poliovirus RNA II Polyadenylic Acis at 3'-Terminus of Poliovirus RNA". ... Wimmer chose to study poliovirus in 1968. Poliovirus is the cause of the horrific disease poliomyelitis, which can cause ... He is best known for his seminal work on the molecular biology of poliovirus and the first chemical synthesis of a viral genome ... The poliovirus synthesis caught global attention, high praise, ridicule and fierce condemnation. Several years later, Wimmer ...

HIV and poliovirus are such viruses. Bacteria with Cas13 make molecules that can dismember RNA, destroying the virus. Tailoring ...

Rapid changes in the sequence of the binding domain have restricted the host range of the poliovirus. Targeting of the brain ... "NMAH - Polio: How the Poliovirus Works". Si.edu. 1 February 2005. Retrieved 28 July 2015. Bruno, R.; Frick, N.; Creange, S.; ... Racaniello VR (2006). "One hundred years of poliovirus pathogenesis". Virology. 344 (1): 9-16. doi:10.1016/j.virol.2005.09.015 ... Kauder SE, Racaniello VR (2004). "Poliovirus tropism and attenuation are determined after internal ribosome entry". Journal of ...

Pearce, Jeremy (July 18, 2007). "Marguerite Vogt, 94, Dies; Biologist and Researcher on Polio Virus". The New York Times. ...

... es share many characteristics with poliovirus. With control of poliovirus infections in much of the world, more ... which also includes poliovirus and echovirus. Enteroviruses are among the most common and important human pathogens, and ... viruses from the gastrointestinal tract that were unrelated to poliovirus, and some of which were oncogenic (cancer-causing). ...

"Poliovirus Extends Survival for Patients With Glioblastoma in Early-Phase Trial". Cure Today. Retrieved 2023-02-13. Duke Cancer ... Cohut, Maria (2020-02-01). "How a modified poliovirus may help fight brain cancer". www.medicalnewstoday.com. Retrieved 2023-02 ... the institute published a study in The New England Journal of Medicine showing how a genetically modified poliovirus therapy ... "Recurrent Glioblastoma Treated with Recombinant Poliovirus". The New England Journal of Medicine. ...

First synthetic polio virus (2002) - Cello, Jeronimo; Paul, Aniko V.; Wimmer, Eckard (9 August 2002). "Chemical Synthesis of ... The first man-made infectious viruses generated without any natural template were of the polio virus and the φX174 ... Bioterrorism Disease X Cello, Jeronimo; Paul, Aniko V.; Wimmer, Eckard (2002-08-09). "Chemical Synthesis of Poliovirus cDNA: ... Poliovirus cDNA: Generation of Infectious Virus in the Absence of Natural Template". Science. 297 (5583): 1016-1018. Bibcode: ...

The plaque assay was developed using poliovirus; the discovery of viral replication in culture was also with poliovirus in 1949 ... and a poliovirus clone was the first infectious DNA clone made of an RNA virus in animals. Along with rhinovirus, poliovirus ... For this reason, poliovirus could not be made in many laboratories until transgenic mice having a CD155 receptor on their cell ... For example, poliovirus receptor is glycoprotein CD155, which is special receptor for human and some other primate species. ...

Drake demonstrated that poliovirus is able to undergo multiplicity reactivation. That is, when polioviruses were irradiated ... Poliovirus can undergo genetic recombination when at least two viral genomes are present in the same host cell. Kirkegaard and ... Poliovirus is a positive single-stranded RNA virus in the family Picornaviridae. Coinfections appear to be common and several ... Kirkegaard K, Baltimore D (November 1986). "The mechanism of RNA recombination in poliovirus". Cell. 47 (3): 433-43. doi: ...