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*  Trans-dichlorodiammineplatinum(II)
"Towards Antitumor Active trans-Platinum Compounds". European Journal of Inorganic Chemistry. 10: 1293-1302. doi:10.1002/ejic. ...
*  Per Teodor Cleve
... including the compounds of platinum. Additionally, Cleve synthesized several hundred complex platinum compounds. Cleve visited ... Cleve worked on the synthesis of complex chemical compounds until 1872. He theorized in 1874 that the element didymium ... Cleve's first work was Några ammoniakaliska chromföreningar (Some compounds of ammonia and chromium, 1861). He also wrote ...
*  Cisplatin
ISBN 978-0-85484-112-7. Rosenberg, B.; Van Camp, L.; Trosko, J. E.; Mansour, V. H. (April 1969). "Platinum compounds: a new ... of Michigan State University discovered that electrolysis of platinum electrodes generated a soluble platinum complex which ... The compound cis-[Pt(NH3)2(Cl)2] was first described by Michele Peyrone in 1845, and known for a long time as Peyrone's salt. ... The nephrotoxicity of platinum-class drugs seems to be related to reactive oxygen species and in animal models can be ...
*  Julia Lermontova
It was in Bunsen's lab that she researched platinum compounds. This research in the development of techniques for the ... which was about the analysis of methyl compounds), and that fall earned her diploma as a Doctor of Chemistry from the ... separation of platinum alloys was suggested to her by Mendeleev. From there, she moved to Berlin, in order to conduct research ...
*  Chloroplatinic acid
Platinum is often isolated from ores or recycled from residues thus. Like many platinum compounds, chloroplatinic acid is used ... The compound is also available as the hexahydrate. Chloroplatinic acid is produced by dissolving platinum metal sponge in aqua ... and for this reason heating of hexachloroplatinic acid can result in insoluble platinum compounds. (H3O)2PtCl6·nH2O → PtCl4 + 2 ... This compound was first reported by John Speier and colleagues from Dow Corning Corporation to catalyze the addition of silyl ...
*  Palladium(II) acetate
It is more reactive than the analogous platinum compound. Depending on the value of n, the compound is soluble in many organic ... Carboxylates of palladium, platinum, and rhodium, and their adducts". Journal of the Chemical Society (Resumed): 3632. doi: ... Palladium(II) acetate is a chemical compound of palladium described by the formula [Pd(O2CCH3)2]n, abbreviated [Pd(OAc)2]n. ... With a 1:2 stoichiometric ratio of palladium atoms and acetate ligands, the compound exists as molecular and polymeric forms. ...
*  Adams' catalyst
When reducing nitro compounds to amines, platinum catalysts are preferred over palladium catalysts to minimize hydrogenolysis. ... Platinum on carbon Platinum black Rhodium-platinum oxide Palladium on carbon Nishimura, Shigeo (2001). Handbook of ... Voorhees, V.; Adams, R. (1922). "The Use of the Oxides of Platinum for the Catalytic Reduction of Organic Compounds". J. Am. ... During the reaction, platinum metal (platinum black) is formed which has been cited to be the active catalyst. Hydrogenation ...
*  Platinum(II) chloride
... is the chemical compound PtCl2. It is an important precursor used in the preparation of other platinum ... colorless dichloro(cycloocta-1,5-diene)platinum(II) (Pt(cod)Cl2), an "organic-soluble" compound containing a labile organic ... Several of these compounds are of interest in homogeneous catalysis in the service of organic synthesis or as anti-cancer drugs ... Platinum(IV) chloride Holleman, A. F.; Wiberg, E. Inorganic Chemistry Academic Press: San Diego, 2001. ISBN 0-12-352651-5. Kerr ...
*  Immunosuppressive drug
... platinum compounds, and others. Cyclophosphamide (Baxter's Cytoxan) is probably the most potent immunosuppressive compound. In ... TNF or the effects of TNF are also suppressed by various natural compounds, including curcumin (an ingredient in turmeric) and ...
*  Kurnakov test
doi:10.1016/S0277-5387(00)81400-X. Kong, Pi-Chang; Rochon, F.D. (1979). "cis- and trans-Platinum compounds of substituted ... platinum(II) chloride deposit on cooling, while the trans compound gives a colourless solution from which snow white needles of ... It is commonly used in platinum mining. Kurnakov test is used to distinguish between cisplatin and transplatin. In hot aqueous ... solution, the cis compound reacts with aqueous thiourea to give a deeper yellow solution from which yellow needles of tetrakis ...
*  Nikolai Semenovich Kurnakov
Kong, Pi-Chang; Rochon, F.D. (1979). "cis- and trans-Platinum compounds of substituted pyrimidines and their products from ... In his later years, he focused his work on platinum chemistry and platinum production. He received several prizes, for example ... In 1893, Kurnakov became professor of inorganic chemistry for his work on the reactions of cis- and trans- platinum complexes ... doi:10.1016/S0277-5387(00)81400-X. Kauffman, George B. (1982). "The Life and Work of Nikolai Semenovich Kurnakov". Platinum ...
*  Oxaliplatin
Like other platinum compounds, its cytotoxicity is thought to result from inhibition of DNA synthesis in cells. In particular, ... The compound features a square planar platinum(II) center. In contrast to cisplatin and carboplatin, oxaliplatin features the ... Oxaliplatin has been compared with other platinum compounds used for advanced cancers, such as cisplatin and carboplatin. In ... Apps, M. G., Choi, E. H. Y., Wheate, N. J. (2015). "The state-of-play and future of platinum drugs". Endocrine-related Cancer. ...
*  Caesium
The analogous platinum compound, red caesium platinide (Cs2Pt), contains the platinide ion that behaves as a pseudochalcogen. ... platinum, tantalum, or tungsten. It forms well-defined intermetallic compounds with antimony, gallium, indium, and thorium, ... Its compounds burn with a blue or violet colour. Caesium forms alloys with the other alkali metals, gold, and mercury (amalgams ... Most caesium compounds contain the element as the cation Cs+ , which binds ionically to a wide variety of anions. One ...
*  Platinum-based antineoplastic
The main dose-limiting side effect of cancer treatment with platinum compounds is neurotoxicity, which causes peripheral ... "Neurotoxicity of platinum compounds: Comparison of the effects of cisplatin and oxaliplatin on the human neuroblastoma cell ... Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival ... Strategies for improving platinum-based anticancer drugs usually involve changes in the neutral spectator ligands, which are ...
*  Group 10 element
None of the other group 10 elements have a known biological role, but platinum compounds have widely been used as anticancer ... platinum (Pt), and perhaps also the chemically uncharacterized darmstadtium (Ds). All are d-block transition metals. All known ... and platinum have had their properties experimentally confirmed. All three elements are typical silvery-white transition metals ... but this remains to be proven conclusively in the laboratory other than for platinum. The group 10 metals share several uses. ...
*  Platinum
... metallic platinum has not been linked to adverse health effects. Compounds containing platinum, such as cisplatin, oxaliplatin ... List of countries by platinum production Mixed metal oxide electrode Platinum in Africa Platinum nanoparticle Iron-platinum ... Platinum is often found chemically uncombined as native platinum and as alloy with the other platinum-group metals and iron ... Platinum(II) and platinum(IV) bromides are known as well. Platinum hexafluoride is a strong oxidizer capable of oxidizing ...
*  Satraplatin
... and cervical cancers have been treated with platinum compounds. All of the marketed platinum analogues must be administered via ... In 1982 Carboplatin was found to be a popular platinum-based compound very similar to cisplatin. After many trials and analyses ... 1993). "Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum ... The compound discovered was later named Cisplatin and clinically used by 1970. After years of use, cisplatin became an ...
*  BRCA1
Persons with NSCLC are often treated with therapeutic platinum compounds (e.g. cisplatin, carboplatin or oxaliplatin) that ... High BRCA1 may protect cancer cells by acting in a pathway that removes the damages in DNA introduced by the platinum drugs. ... Patients having sporadic ovarian cancer who were treated with platinum drugs had longer median survival times if their BRCA1 ... Among individuals with NSCLC, low expression of BRCA1 in the primary tumor correlated with improved survival after platinum- ...
*  Crosslinking of DNA
Individuals with NSLC are often treated with therapeutic platinum compounds (e.g. cisplatin, carboplatin or oxaliplatin) (see ... Psoralens are natural compounds (furocoumarins) present in plants. These compounds intercalate into DNA at 5'-AT sequence sites ... These compounds have a bis-(2-ethylchloro)amine core structure, with a variable R-group, with the two reactive functional ... The planar compound links to nucleobases through water displacement of one or both of its chloride groups, allowing cisplatin ...
*  Dichloro(cycloocta-1,5-diene)platinum(II)
Dichloro(1,5-cyclooctadiene)platinum(II) (Pt(cod)Cl2) is an organometallic compound of platinum. This colourless solid, which ... is an entry point to other platinum compounds through the displacement of the cod and/or chloride ligands. It is prepared from ... J. L. Butikofer, E. W. Kalberer, W. C. Schuster, and D. M. Roddick, "The Crystal Structure of Dichloro(norbornadiene)platinum( ... Dimethyl-Platinum(II)". Inorg. Synth. Inorganic Syntheses. 31: 284-286. doi:10.1002/9780470132623.ch49. ISBN 978-0-470-13262-3 ...
*  NAMI-A
It has also been found that when compared to highly cytotoxic platinum compounds, NAMI-A is much less cytotoxic and has a ... Unlike cisplatin, a platinum based drug, it has been shown in-vivo that NAMI-A doesn't inhibit primary tumor growth but ... Ruthenium, unlike traditional platinum complexes such as cisplatin, shows greater resistance to hydrolysis and more selective ... "Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A" (PDF). ac.els-cdn.com. ...
*  History of cancer chemotherapy
Cisplatin, a platinum-based compound, was discovered by a Michigan State University researcher, Barnett Rosenberg, working ... soon initiated a series of investigations and studies into the effects of platinum compounds on cell division, culminating in ... They exchanged a nitrogen molecule for sulfur and had a more stable compound in nitrogen mustard. A year into the start of ... and others at the Institute of Cancer Research in the United Kingdom extended the clinical usefulness of the platinum compounds ...
*  Magnus' green salt
... first reported the compound. The compound has an unusual structure, consisting of a chain of platinum atoms, and it exhibits ... Platinum Metals Rev. 48 (3): 91-100. doi:10.1595/147106704X1504. Bremi, J.; Caseri, W. & Smith, P. (2001). "A new compound ... which is very unusual for platinum compounds. This species has been of interest in materials chemistry and solid-state physics ... The compound may be prepared by combining aqueous solutions of [Pt(NH3)4]2+ and [PtCl4]2−, which gives a deep green solid ...
*  Henrik Gustaf Söderbaum
Söderbaum's scientific activities until 1896 were devoted partially to the studies complex platinum compounds, and partially ... "Studies of platooxalyl compounds"), and was made docent in chemistry the same year. He was made a senior lecturer in chemistry ... and primarily to the synthesis and investigation of organic compounds of various classes. Later, he partially devoted himself ...
*  Platinum(II) sulfide
... is the inorganic compound with the formula PtS. It is a green solid, insoluble in all solvents. The ... A related compound is platinum disulfide, PtS2. Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed ... compound adopts an unusual structure, being composed of square planar Pt and tetrahedral sulfide centers. ...
*  William Christopher Zeise
... leading to a series of platinum-based organometallic compounds. One of these compounds, originally referred to by Zeise himself ... He is best known for synthesising one of the first organometallic compounds, named Zeise's salt in his honour. He also ... In 1823 while still in the small laboratory at Nørregade he identified a new family of sulfur-containing compounds, calling ... In 1830, Zeise attempted to react platinum chloride with ethanol, ...