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*  CD109
... the platelet-specific Gov antigen system, implicated in refractoriness to platelet transfusion, neonatal alloimmune ... "Platelet and granulocyte glycoprotein polymorphisms". Transfusion medicine (Oxford, England). 10 (3): 157-74. doi:10.1046/j. ... Lewandrowski U, Moebius J, Walter U, Sickmann A (2006). "Elucidation of N-glycosylation sites on human platelet proteins: a ... 1990). "Gova/b alloantigen system on human platelets". Blood. 75 (11): 2172-6. PMID 2346781. Lin M, Sutherland DR, Horsfall W, ...
*  Blood donation
doi:10.1111/j.1365-3148.2006.00694_4.x. "Transfusion Handbook, summary information for Platelets". National Blood Transfusion ... "In Vitro Evaluation of Buffy Coat Derived Platelet Concentrates in SSP+ Platelet Storage Medium". Transfusion Medicine. 16: 26 ... This process is especially common for plasma and platelets. For direct transfusions a vein can be used but the blood may be ... Retrieved 2009-10-26 "Indications for Platelet Transfusion Therapy". Southeastern Community Blood Center. Retrieved 2008-06-10 ...
*  Autotransfusion
The red cells and platelet poor plasma can be given back to the patient through intravenous transfusion during or after surgery ... The platelet rich plasma can be mixed with calcium and thrombin to create a product known as autologous platelet gel. This is ... The autotransfusionist monitors blood loss and will recommend the transfusion of fresh frozen plasma (FFP) and platelets when ... platelet poor plasma, and platelet rich plasma. Blood can be drawn from the patient just prior to surgery and then separated. ...
*  Plateletpheresis
Platelet count increase as well as platelet survival after transfusion is related to the dose of platelets infused and to the ... Not all platelet transfusions use platelets collected by automated apheresis. The platelets can also be separated from ... platelet increment at one hr x BSA (m2) / # platelets infused x 1011 Expected platelet increase (per μL) = platelets infused x ... Early platelet transfusions used a filter to remove white blood cells at the time of transfusion. It takes a trained person ...
*  Platelet transfusion
... , also known as platelet concentrate, is used to prevent or treat bleeding in people with either a low ... There is little evidence for the effectiveness of platelet transfusions or the optimal dose when a person with a low platelet ... This study's authors suggested that a high-dose platelet transfusion strategy may lead to a higher rate of transfusion-related ... A review in people with haematological malignancies found that overall giving platelet transfusions when the platelet count is ...
*  Platelet transfusion refractoriness
Pre-transfusion platelet count Post-transfusion platelet count: the post-transfusion blood sample for this measurement should ... Post-transfusion platelet count - Pre-transfusion platelet count)(BSA) ÷ (number of platelets transfused). A CCI greater than ... Platelet transfusion refractoriness is the failure to achieve the desired level of blood platelets in a patient following a ... Platelet transfusion refractoriness is typically diagnosed using the corrected count increment, which requires 4 items of ...
*  Devaanshi Mehta
"14-year-old needs regular platelet transfusions". Retrieved 26 February 2013. "Best foot forward for transplant girl". Harrow ... June 2012 at the Great Ormond Street Hospital after a lengthy battle with her lung condition and chronic platelet transfusion ... However, she was left chronically platelet and red cell dependent after the transplant. In addition, she inherited her brothers ... rarer blood type AB-. Therefore it became increasingly difficult to source negative platelets for her, and she organised ...
*  Jacobsen syndrome
Consecutively Platelet transfusion and ddAVP can be carried out. Medication that interferes with platelet count should be ... There are a variety of tests that can be carried out like karyotype, cardiac echocardiogram, a renal sonogram, a platelet count ... which is a bleeding disorder and causes a lifelong risk of abnormal bleeding and bruising due to dysfunction in the platelets. ...
*  CD36
... despite multiple platelet transfusions, continued to exhibit low platelet levels. This condition is known as refractoriness to ... platelet transfusion. Subsequent studies have shown that CD36 found on the surface of platelets. This antigen is recognized by ... or platelets alone (type 2). Type 2 has been divided into two subtypes - a and b. Deficiency restricted to the platelets alone ... "CD36 deficiency is frequent and can cause platelet immunization in Africans". Transfusion. 39 (8): 873-9. doi:10.1046/j.1537- ...
*  X linked thrombocytopenia
In the event of significant bleeding, platelet transfusions should be administered. Circumcision should be avoided for infant ... Platelets are cell fragments in the blood that aid in clotting. Platelets are produced in the bone marrow. Normal platelet ... Individuals with XLT usually have drastically reduced platelet counts, typically less than 70,000 platelets per µL of blood. ... Not only are there fewer platelets circulating, but individuals with XLT also have smaller platelets. Fewer and smaller ...
*  Blood bank
Platelet transfusion, is transfused to those who suffer from low platelet count. This can be stored at room temperature for 5-7 ... Transfusions of platelets are comparatively far less numerous, but they present unique storage/management issues. Platelets may ... Platelets are typically pooled before transfusion and have a shelf life of 5 to 7 days, or 3 days once the facility that ... Transfusion before World War I Plasma Equipment and Packaging, and Transfusion Equipment Marik PE, Corwin HL (2008). "Efficacy ...
*  Induced stem cells
Functional platelets are generated throughout the culture allowing the prospective collection of several transfusion units from ... Road blocks in making platelets for transfusion. J Thromb Haemost 2015; 13 (Suppl. 1): S55-S62. doi:10.1111/jth.12942 Riddell, ... A significant problem for multitransfused patients is refractoriness to platelet transfusions. Thus, the ability to generate ... RBC transfusion is necessary for many patients. However, to date the supply of RBCs remains labile. In addition, transfusion ...
*  Bernard-Soulier syndrome
In terms of treatment/management, bleeding events can be controlled by platelet transfusion. Most heterozygotes, with few ... giant platelets may reach the size of red blood cells. The large platelets and low platelet count in BSS are seemingly due to ... BSS is a giant platelet disorder, meaning that it is characterized by abnormally large platelets. Bernard-Soulier syndrome ... and enlarged platelets, Bernard-Soulier syndrome is associated with quantitative or qualitative defects of the platelet ...
*  Fludarabine
Some patients require blood and platelet transfusion, or G-CSF injections to boost neutrophil counts. Fludarabine is associated ... The profound lymphopenia caused by fludarabine renders patients susceptible to transfusion-associated graft versus host disease ... an oftentimes fatal complication of blood transfusion. For this reason, all patients who have ever received fludarabine should ...
*  Intracerebral hemorrhage
Frozen plasma, vitamin K, protamine, or platelet transfusions are given in case of a coagulopathy. Fosphenytoin or other ...
*  Wiskott-Aldrich syndrome
For severely low platelet counts, patients may require platelet transfusions or removal of the spleen. For patients with ... In both conditions the defective platelets are through to be removed from circulation by the spleen and/or liver, leading to ... Several proteins can serve as NPFs, and it has been observed that in WAS platelets the Arp2/3 complex functions normally, ... Often, leukemia may be suspected on the basis of low platelets and infections, and bone marrow biopsy may be performed. ...
*  Blood product
Cryoprecipitate Cryosupernatant Fresh frozen plasma PF24 Platelet transfusion Red blood cells The Clinical Use of Blood ... Whole blood is not commonly used in transfusion medicine. Blood components include: red blood cell concentrates or suspensions ... platelets produced from whole blood or via apheresis; plasma; and cryoprecipitate. Plasma derivatives are plasma proteins ...
*  Thromboelastography
Thus, a depressed MA is better treated with platelet transfusion or medications that improve platelet function, such as DDAVP. ... Lastly, the platelet map TEG aims to determine to what degree platelet function may be inhibited due to pharmacologic ... Aspirin inhibits platelet function via the AA pathway while clopidogrel inhibits platelet function via the ADP pathway; thus, ... The speed at which the sample coagulates depends on the activity of the plasma coagulation system, platelet function, ...
*  Blood donation in England
... patients may need platelet transfusions to replace those lost through bleeding. Platelets are often life-saving and special in ... As platelets can only be stored for a few days, regular and frequent donors are in great demand and that is why platelet donors ... Most platelet donations are given to patients who are unable to make enough platelets in their bone marrow. For example, ... A constant supply is vital because platelets only last five days once collected. People who give plasma and/or platelets can ...
*  Immune thrombocytopenic purpura
Platelet transfusions may be used in severe bleeding together with a very low count. Sometimes the body may compensate by ... ITP is diagnosed by a low platelet count in a complete blood count (a common blood test). However, since the diagnosis depends ... Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) ... ITP is an autoimmune disease with antibodies detectable against several platelet surface antigens. ...
*  Juvenile myelomonocytic leukemia
Radiation to the spleen does not generally result in a decrease in spleen size or reduction of platelet transfusion requirement ... low platelet count in blood). Most of these conditions are common, nonspecific signs and symptoms. Children with JMML and ... Indian Journal of Hematology and Blood Transfusion. 29 (3): 164-6. doi:10.1007/s12288-012-0164-9. PMC 3710560 . PMID 24426365. ... with other chemotherapy drugs have produced results such as decrease in organ size and increase or normalization of platelet ...
*  TAR syndrome
Treatments range from platelet transfusions to surgery aimed at either centralizing the hand over the ulna to improve ... The infant mortality rate has been curbed by new technology, including platelet transfusions, which can even be performed in ... For most people with TAR, platelet counts improve as they grow out of childhood. The incidence is 0.42 per 100,000 live births ... Symptoms of thrombocytopenia, or a lowered platelet count, leads to bruising and potentially life-threatening hemorrhage. ...
*  Human platelet antigen
... post-transfusion purpura and some cases of platelet transfusion refractoriness to infusion of donor platelets. A nomenclature ... Human platelet antigens (HPA) are polymorphisms in platelet antigens. These can stimulate production of alloantibodies, ( ... To date, 24 platelet-specific alloantigens have been defined by immune sera, of which 12 are grouped in six biallelic systems ( ... was devised by International Society of Blood Transfusion (ISBT), platelet working party to overcome problems generated by many ...
*  Giant platelet disorder
Platelet transfusion is the main treatment for people presenting with bleeding symptoms. There have been experiments with DDAVP ... Platelet Disorders Overview of Platelet Disorders at eMedicine Mhawech, Paulette (2000). "Inherited Giant Platelet Disorders" ( ... Giant platelet disorder occurs for inherited diseases like Bernard-Soulier syndrome, gray platelet syndrome and May-Hegglin ... This would utilize platelet aggregation studies and flow cytometry. Giant platelet disorders can be further categorized: caused ...
*  Thrombocytopenia
Frequent platelet transfusions are required to keep the patient from bleeding to death before the transplant can be performed, ... Platelet transfusions are not routinely used to treat HIT because thrombosis, not bleeding, is the primary problem. Warfarin is ... A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. These limits are determined by ... Corticosteroids may be used to increase platelet production. Lithium carbonate or folate may also be used to stimulate platelet ...
*  Joe Dolan
Doctors diagnosed a low blood platelet count and Dolan began a series of blood transfusions, After each, he felt better for a ... Despite the blood transfusions and other medical interventions, Dolan became weaker and he was finally discharged from the ...
*  Boris Petrikovsky
Prenatal evaluation and in utero platelet transfusion for thrombocytopenia absent radii syndrome. Prenat Diagn 1994; 14:892-6 ... In 1994, he, along with a group of Pediatric Hematologists, performed the first ever intrauterine transfusion of a thrombocyte ...