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*  Multiple electrode aggregometry
cAMP inhibits platelet aggregation, and decreased amounts of cAMP in platelets lead to platelet aggregation. The PGE1 reagent ... Prostaglandin E1 (PGE1) is a platelet inhibitor that causes an increase in cyclic adenosine monophosphate (cAMP) in platelets ... Binding of fibrinogen to GPIIb/IIIa receptors leads to platelet-to-platelet bridges and results in platelet aggregation. ... TXA2 increases platelet aggregation, promotes degranulation and stimulates platelet activation. Inhibition of COX1, as with ...
*  Thromboregulation
Kistrin is a protein inhibitor of platelet aggregation. It belongs to the homologous family of glycoprotein IIb-IIa antagonists ... but platelet aggregation must grow exponentially to form a platelet thrombus and prevent blood loss. Platelet aggregation ... Some thromboregulators enhance platelet aggregation and some others inhibit the process. Platelet aggregation plays a critical ... These inhibitors are substances that prevent the clot formation by preventing platelet adhesion. Platelet inhibition is ...
*  Thrombin
As part of its activity in the coagulation cascade, thrombin also promotes platelet activation and aggregation via activation ... Thrombin bound to thrombomodulin activates protein C, an inhibitor of the coagulation cascade. The activation of protein C is ... Heparin increases the affinity of antithrombin to thrombin (as well as factor Xa). The direct thrombin inhibitors, a newer ... The MEROPS online database for peptidases and their inhibitors: S01.217 GeneReviews/NCBI/NIH/UW entry on Prothrombin ...
*  Indobufen
... is a platelet aggregation inhibitor. It acts as a reversible cyclooxygenase inhibitor. The Merck Index, 12th Edition ...
*  Picotamide
... is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor ... inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor. Picotamide is licensed in ...
*  Ditazole
... is a platelet aggregation inhibitor. It is marketed in Spain and Portugal under the trade name Ageroplas. Martindale's ...
*  Bencyclane
... is an antispasmodic, vasodilator & platelet aggregation inhibitor. https://books.google.co.uk/books?isbn=1475720858 ...
*  White-winged vampire bat
... platelet aggregation inhibitors, which prevent the formation of blood clots; and other anticoagulants, which also prevent blood ...
*  Cinnamtannin B1
Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor. Life sciences, 82(19), 977-982. doi:10.1016/j.lfs. ... and anti-platelet aggregation that may protect damaged tissues in wounds Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; ...
*  3-Pyridylnicotinamide
"Design and Synthesis of Piperidine-3-carboxamides as Human Platelet Aggregation Inhibitors". Journal of Medicinal Chemistry. 38 ...
*  Penicillium herquei
... a new platelet aggregation inhibitor produced by Penicillium herquei Fg-372". The Journal of Antibiotics. 49 (1): 50-3. doi: ... a New Platelet Aggregation Inhibitor Produced by Penicillium herquei Fg-372". ChemInform. 27 (27): no. doi:10.1002/chin. ...
*  Ornatin
In molecular biology, ornatin is a potent glycoprotein IIb-IIIa (GP IIb-IIIa) antagonist and platelet aggregation inhibitor ... potent glycoprotein IIb-IIIa antagonists and platelet aggregation inhibitors from the leech Placobdella ornata". Eur. J. ...
*  Ticagrelor
... (trade name Brilinta, Brilique, and Possia) is a platelet aggregation inhibitor produced by AstraZeneca. Ticagrelor ... Inhibitors of the liver enzyme CYP3A4, such as ketoconazole and possibly grapefruit juice, increase blood plasma levels of ... are not significantly influenced by P-gp inhibitors. In the US a boxed warning states that use of ticagrelor with aspirin doses ...
*  Carbasalate calcium
... is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor. It ...
*  Triflusal
... is a platelet aggregation inhibitor that was discovered and developed in the Uriach Laboratories, and commercialised ... Triflusal is a selective platelet antiaggregant through; blocks cyclooxygenase inhibiting thromboxane A2, preventing ... aggregation preserves vascular prostacyclin, thus promoting anti-aggregant effect blocks phosphodiesterase thereby increasing ...
*  Sibrafiban
... which is a platelet aggregation inhibitor. It was being developed for secondary prevention of arterial thrombosis following ...
*  Hirudo medicinalis
... platelet aggregation inhibitors (most notably apyrase, collagenase, and calin), vasodilators, and proteinase inhibitors. It is ...
*  Russellysin
... platelet aggregation inhibitor)-like and C-type lectin-like domains". J. Biol. Chem. 267: 14109-14117. PMID 1629211. ...
*  Tick
... and keep the blood from clotting by excreting an anticoagulant or platelet aggregation inhibitor. Ticks find their hosts by ...
*  Abciximab
... a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets ... In practice, platelet aggregation gradually returns to normal about 96 to 120 hours after discontinuation of the drug. ... While abciximab has a short plasma half-life, due to its strong affinity for its receptor on the platelets, it may occupy some ... However, its effects on platelet function can be seen for up to 48 hours after the infusion has been terminated, and low levels ...
*  Tirofiban
... constitutes an antithrombotic, specifically an inhibitor of platelet aggregation. Tirofiban is a modified version of ... Tirofiban is a small molecule inhibitor of the protein-protein interaction between fibrinogen and the platelet integrin ... Tirofiban is a synthetic, non-peptide inhibitor of the interaction of fibrinogen with the integrin glycoprotein (GP) IIb/IIIa ... 1. Discovery and Design of Exosite Inhibitors". Journal of Medicinal Chemistry. American Chemical Society. 35 (24): 4640-4642. ...
*  Desmoteplase
"Hawkey C. Inhibitor of platelet aggregation present in saliva of the vampire bat Desmodus rotundus. Br J Haematol.1967;13(6): ...
*  Prostaglandin D2 synthase
PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is ...
*  Insects in medicine
This diverse range of compounds may include: inhibitors of platelet aggregation, ADP, arachidonic acid, thrombin, and PAF. ... Additionally, Ixolaris, a tissue factor inhibitor has been shown to block primary tumor growth and angiogenesis in a ... Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model. J. Thromb. Haemost. ... Tick saliva is a potent inhibitor of endothelial cell proliferation and angiogenesis. Thromb. Haemost. 94, 167e174. Maritz- ...
*  Psychotridine
Potent Inhibitors of the Aggregation of Human Platelets". Planta Medica. 51 (4): 300-3. doi:10.1055/s-2007-969496. PMID ...
*  Glycoprotein IIb/IIIa inhibitors
They work by preventing platelet aggregation and thrombus formation. They do so by inhibition of the GpIIb/IIIa receptor on the ... In medicine, glycoprotein IIb/IIIa inhibitors, also GpIIb/IIIa inhibitors, is a class of antiplatelet agents. Several GpIIb/ ... IIIa inhibitors exist: abciximab (ReoPro) eptifibatide (Integrilin) tirofiban (Aggrastat) roxifiban orbofiban Glycoprotein IIb/ ... IIIa inhibitors are frequently used during percutaneous coronary intervention (angioplasty with or without intracoronary stent ...
*  Echis carinatus
... a potent inhibitor of platelet aggregation from Echis carinatus: synthesis and biological activity of selected analogs". Proc. ...