... is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes ... In 1897, William H. Welch created the name Plasmodium falciparum, which ICZN formally adopted in 1954. P. falciparum assumes ... Bousema, T.; Drakeley, C. (2011). "Epidemiology and Infectivity of Plasmodium falciparum and Plasmodium vivax Gametocytes in ... The Plasmodium Genome Resource UCSC Plasmodium Falciparum Browser Gene info at Kyoto University (CS1 errors: periodical ignored ...
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a family of proteins present on the membrane surface of red ... Zhang Y, Jiang N, Chang Z, Wang H, Lu H, Wahlgren M, Chen Q (2014). "The var3 genes of Plasmodium falciparum 3D7 strain are ... In humans, malaria can be caused by five Plasmodium parasites, namely P. falciparum, P. vivax, P. malariae, P. ovale and P. ... Hviid, Lars; Jensen, Anja T.R. (2015). "PfEMP1 - A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria ...
Plasmodium Falciparum; in collaboration with Amico Bignami, 1900. Considerations on the treatment of malaria, 1933. On the ... called terzana maligna was attributed to Plasmodium falciparum, while a milder form of the disease called terzana benigna was ... they could therefore describe all the phases of the sporogonic cycle of Plasmodium Vivax from the Cocists stage of 42 hours ... and together with Bastianelli and Bignami he clarified the biological pattern of plasmodia from Anopheles mosquito to man in ...
The DNA of Plasmodium falciparum shows the same pattern of diversity as its human hosts, with greater diversity in Africa than ... Shortt HE, Fairley NH, Covell G, Shute PG, Garnham PC (1948). "Pre-erythrocytic Stage of Plasmodium Falciparum". Br Med J. 2 ( ... Nerlich AG, Schraut B, Dittrich S, Jelinek T, Zink AR (2008). "Plasmodium falciparum in Ancient Egypt". Emerg Infect Dis. 14 (8 ... Humans may have originally caught P. falciparum from gorillas. P. vivax, another malarial Plasmodium species among the six that ...
Rubio, J P; Thompson, J K; Cowman, A F (1 August 1996). "The var genes of Plasmodium falciparum are located in the subtelomeric ... The advantages of subtelomeres have been studied in different species such as Plasmodium falciparum, Drosophila melanogaster, ... Scherf, Artur; Lopez-Rubio, Jose Juan; Riviere, Loïc (October 2008). "Antigenic Variation in Plasmodium falciparum". Annual ... The subtelomeres of such diverse species as humans, Plasmodium falciparum, Drosophila melanogaster, and Saccharomyces ...
Dalexandri, F.; Kimura, E.; Peres, V.; Katzin, A. (2006). "Protein dolichylation in Plasmodium falciparum". FEBS Letters. 580 ( ... including the malarial parasite Plasmodium falciparum. Hjertman, M.; Wejde, J.; Dricu, A.; Carlberg, M.; Griffiths, W. J.; ...
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Glycophorin B acts as a receptor for erythrocyte binding Ligand (EBl-1) of Plasmodium falciparum involved in malaria. Both the ... Field SP, Hempelmann E, Mendelow BV, Fleming AF (February 1994). "Glycophorin variants and Plasmodium falciparum: protective ... Facer CA (1983). "Erythrocyte sialoglycoproteins and Plasmodium falciparum invasion". Trans. R. Soc. Trop. Med. Hyg. 77 (4): ... "Glycophorin B as an EBA-175 independent Plasmodium falciparum receptor of human erythrocytes". Mol. Biochem. Parasitol. 64 (1 ...
... durae Plasmodium egerniae Plasmodium elongatum Plasmodium eylesi Plasmodium fairchildi Plasmodium falciparum Plasmodium fallax ... Plasmodium cynomolgi, Plasmodium fragile, Plasmodium inui, Plasmodium fieldi, Plasmodium hylobati, Plasmodium inui, Plasmodium ... Plasmodium adunyinkai Plasmodium bitis Plasmodium bowiei Plasmodium brasiliense Plasmodium brucei Plasmodium bufoni Plasmodium ... Plasmodium accipiteris Plasmodium achiotense Plasmodium achromaticum Plasmodium acuminatum Plasmodium adleri Plasmodium ...
"Plasmodium falciparum (ID 33) - Genome - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-12-30. "Index of /genomes/refseq/protozoa/ ... "Index of /genomes/refseq/protozoa/Plasmodium_falciparum/latest_assembly_versions/GCF_000002765.5_GCA_000002765". ftp.ncbi.nih. ...
Treatment of Uncomplicated Plasmodium falciparum Malaria. World Health Organization. 2015-01-01. Archived from the original on ... Artemether is an antimalarial drug for uncomplicated malaria caused by P. falciparum (and chloroquine-resistant P. falciparum) ... "Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum ... The World Health Organization (WHO) recommends the treatment of uncomplicated P. falciparum with artemisinin-based combination ...
Dongare, H. C.; Khatib, K. I. (2016). "JCDR - Exchange blood transfusion, Malaria, Plasmodium falciparum". Journal of Clinical ...
Plasmodium falciparum is the species responsible for more than 95% deaths caused by malaria. The WHO estimates there were 247 ... August 2018). "Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults". The American Journal of Tropical Medicine and ... Sanaria has developed the technology to grow and harvest aseptic, purified Plasmodium falciparum (Pf) SPZ and formulate them as ... May 2017). "Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria ...
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Tilley L, Straimer J, Gnädig NF, Ralph SA, Fidock DA (2016). "Artemisinin Action and Resistance in Plasmodium falciparum". ... Wicht KJ, Mok S, Fidock DA (September 2020). "Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria". Annual ... Ouji M, Augereau JM, Paloque L, Benoit-Vical F (2018). "Plasmodium falciparum resistance to artemisinin-based combination ... 2014). "Spread of artemisinin resistance in Plasmodium falciparum malaria". The New England Journal of Medicine. 371 (5): 411- ...
Krishna has made significant contributions to the understanding of membrane transporters in Plasmodium falciparum, a parasite ... July 2004). "Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number". The Lancet. 364 (9432): 438 ... August 2003). "Artemisinins target the SERCA of Plasmodium falciparum". Nature. 424 (6951): 957-961. Bibcode:2003Natur.424.. ... August 2006). "Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, ...
... s are membranous structures seen in the red blood cell during infection with Plasmodium falciparum. The function ... Mundwiler-Pachlatko E, Beck HP (December 2013). "Maurer's clefts, the enigma of Plasmodium falciparum". Proceedings of the ... they appear to play a role in trafficking of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) and other adhesins ... Maurer's clefts appear in the cytosol of red blood cells 2 to 4 hours after invasion by P. falciparum. They originally appear ...
Arnou B, Montigny C, Morth JP, Nissen P, Jaxel C, Møller JV, Maire M (June 2011). "The Plasmodium falciparum Ca(2+)-ATPase ... Kimura M, Yamaguchi Y, Takada S, Tanabe K (April 1993). "Cloning of a Ca(2+)-ATPase gene of Plasmodium falciparum and ... PfATP6, also known as PfSERCA or PfATPase6, is a calcium ATPase gene encoded by the malaria parasite Plasmodium falciparum. The ... December 2005). "Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA- ...
Hempelmann E, Marques HM (September 1994). "Analysis of malaria pigment from Plasmodium falciparum". J Pharmacol Toxicol ... Hempelmann E (2007). "Hemozoin biocrystallization in Plasmodium falciparum and the antimalarial activity of crystallization ... "Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum". Proc Natl Acad Sci U S A. 110 (14): 5392-7 ... During its intraerythrocytic asexual reproduction cycle Plasmodium falciparum consumes up to 80% of the host cell hemoglobin. ...
Plasmodium falciparum causes the majority of infections. Of the 20 countries with the highest incidence of maternal mortality, ...
Eight months after the MDA, Plasmodium falciparum prevalence had decreased from 14% to 1%. The only reported project with an ... Eyles DE, Hoo CC, Warren M, Sandosham AA (November 1963). "Plasmodium falciparum resistant to chloroquine in Cambodia". Am. J. ... Payne D (April 1988). "Did medicated salt hasten the spread of chloroquine resistance in Plasmodium falciparum?". Parasitol. ... Kondrashin AV, Sanyal MC (December 1985). "Mass drug administration in Andhra Pradesh in areas under Plasmodium falciparum ...
2009). Artemisinin Resistance in Plasmodium falciparum Malaria. New England Journal Of Medicine, 361, 455-467. Doliwa C, ... and as of 2012 artemisinin-resistant Plasmodium falciparum has emerged in western Cambodia and western Thailand.Toxoplasma ... Plasmodium vivax has become chloroquine and sulfadoxine-pyrimethamine resistant a few decades ago, ...
Malaria is caused by apicomplexans, primarily Plasmodium falciparum, which largely reside in red blood cells and itself ... "Artemisinin Action and Resistance in Plasmodium falciparum". Trends in Parasitology. 32 (9): 682-696. doi:10.1016/j.pt.2016.05. ... "Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria" (PDF). The Cochrane Database of ... 2009). "Artemether‐Lumefantrine versus Dihydroartemisinin‐Piperaquine for Falciparum Malaria: A Longitudinal, Randomized Trial ...
Hempelmann E, Marques HM (September 1994). "Analysis of malaria pigment from Plasmodium falciparum". J Pharmacol Toxicol ... Heme biocrystallization has been found in blood feeding organisms of great medical importance including Plasmodium, Rhodnius ...
Azithromycin monotherapy or combination therapy has not shown effectiveness in treating Plasmodium falciparum or Plasmodium ... Severe malaria is usually caused by P. falciparum (often referred to as falciparum malaria). Symptoms of falciparum malaria ... Five species of Plasmodium can infect and be spread by humans. Most deaths are caused by P. falciparum, whereas P. vivax, P. ... It binds the Plasmodium falciparum circumsporozoite protein (CSP-1), essential to disease, and makes it ineffective. Drug ...
Malaria due to Plasmodium falciparum is a major selective factor in human evolution. It has influenced mutations in HBB in ... Verra F, Mangano VD, Modiano D (2009). "Genetics of susceptibility to Plasmodium falciparum: from classical malaria resistance ... HbC provides near full protection against Plasmodium falciparum in homozygous (CC) individuals and intermediate protection in ... "Haemoglobin C and S in natural selection against Plasmodium falciparum malaria: a plethora or a single shared adaptive ...
Plasmodium falciparum resistance to piperaquine driven by PfCRT. Lancet Infect Dis 19: 1168-9. Structure and drug resistance of ... Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and ... Cell Chem Biol (in press). Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite ... Dhingra, Satish K.; Small-Saunders, Jennifer L.; Ménard, Didier; Fidock, David A. (2019-11-01). "Plasmodium falciparum ...
"Plasmodium falciparum Apicoplast Drugs: Targets or Off-Targets?". Chemical Reviews. 112 (3): 1269-83. doi:10.1021/cr200258w. ... "Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum". ... Parasites in the apicomplexan genus Plasmodium are the causative agents of malaria. Studies of C. velia and V. brassicaformis ... Silico Search for Target Similarity Identifies Several Approved Drugs with Potential Activity against the Plasmodium falciparum ...
Plasmodium falciparum was probably not able to gain a foothold among African populations until larger sedentary communities ... Cortés A, Mellombo M, Mgone CS, Beck HP, Reeder JC, Cooke BM (2005). "Adhesion of Plasmodium falciparum-infected red blood ... Rihet P, Flori L, Tall F, Traore AS, Fumoux F (2004). "Hemoglobin C is associated with reduced Plasmodium falciparum ... Brenda AkinyiI Webala, "Prevalence of Fetal Hemoglobin and Antibody Responses to Plasmodium falciparum Antigens in Sickle Cell ...
Plasmodium falciparum is the major cause of infection. Senegal has made significant progress against malaria and remains a ...