*Piperidine

... is a widely used secondary amine. It is widely used to convert ketones to enamines. Enamines derived from piperidine ... Both men obtained piperidine by reacting piperine with nitric acid. Industrially, piperidine is produced by the hydrogenation ... Piperidine prefers a chair conformation, similar to cyclohexane. Unlike cyclohexane, piperidine has two distinguishable chair ... Piperidine is also commonly used as a base for the deprotection of Fmoc-amino acids used in solid-phase peptide synthesis. ...

*Piperidine N-piperoyltransferase

Other names in common use include piperidine piperoyltransferase, and piperoyl-CoA:piperidine N-piperoyltransferase. Geisler JG ... piperidine Thus, the two substrates of this enzyme are (E,E)-piperoyl-CoA and piperidine, whereas its two products are CoA and ... In enzymology, a piperidine N-piperoyltransferase (EC 2.3.1.145) is an enzyme that catalyzes the chemical reaction (E,E)- ... The systematic name of this enzyme class is (E,E)-piperoyl-CoA:piperidine N-piperoyltransferase. ...

*1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine

... is a stimulant of the piperidine class which acts as a potent and selective ... "Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine ( ...

*N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate

N,O-Dimethyl-4β-(2-naphthyl)piperidine-3β-carboxylate (DMNPC) is a piperidine based stimulant drug which is synthesised from ... Naphthylamphetamine Naphyrone List of cocaine analogues "Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. ...

*Encainide

2-(o-Acylaminophenethyl)piperidines". Journal of Medicinal Chemistry. 16 (9): 1015-1020. doi:10.1021/jm00267a012. PMID 4745503 ...

*Prodine

Ziering and Lee found that embellishing this structure via the incorporation of a 3-methyl group into the piperidine nucleus ... Ziering, A.; Lee, J. (1947). "Piperidine Derivatives. V. 1,3-Dialkyl-4-Aryl-4-Acyloxypiperidines". The Journal of Organic ... "Piperidine Derivatives. Part III. 4-Arylpiperidines". The Journal of Organic Chemistry. 12 (6): 894. doi:10.1021/jo01170a022. ...

*MPTP

Lee, J.; Ziering, A.; Heineman, S. D.; Berger, L. (1947). "Piperidine Derivatives. Part II. 2-Phenyl- and 2-Phenylalkyl- ... Piperidines". Journal of Organic Chemistry. 12 (6): 885-893. doi:10.1021/jo01170a021. Vinken, P. J.; Bruyn, G. W. (1994). ...

*Desmethylprodine

Structural analogs of desmethylprodine with different N-substituents than a methyl group on the piperidine have been ... "Piperidine derivatives; 1,3-dialkyl-4-aryl-4-acyloxypiperidines". The Journal of Organic Chemistry. 12 (6): 911-914. doi: ...

*Glutarimide

... is a chemical compound featuring a piperidine ring with two ketones attached next to the nitrogen. It is a ...

*Fenpiverinium

Vardanyan, Ruben (2017). Piperidine-Based Drug Discovery. Elsevier. ISBN 9780128134283. Consolidated List of Products - Whose ...

*CPCA

Å distant from the 3α-substituted piperidine ring. Noticeably, high potency at the DAT of dimeric piperidine-based esters and ... "Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ... Petukhov, P. A.; Zhang, M.; Johnson, K. J.; Tella, S. R.; Kozikowski, A. P. (2001). "Sar studies of piperidine-based analogues ... This model was successfully used for the design of a novel piperidine-based DAT inhibitor, that is economically affordable to ...

*Benzatropine

Diphenylpyraline (piperidine replaces the tropane). List of benzatropine analogues CRL-40,941 DiMascio, A.; Bernardo, D. L.; ...

*Lythranidine

... is classified as an alkaloid and it contains a piperidine group that defines the synthesis of the structure via ... 1, 1991, 611-616 Pinder, A. R. (1992). "Azetidine, pyrrole, pyrrolidine, piperidine, and pyridine alkaloids". Natural Product ... 6-disubstituted piperidine ring. Lythranidine was first synthesized by Fuji Kaoru, Kohei Ichikawa and Eiichi Fujita in 1971. ...

*Pipecolic acid

... (piperidine-2-carboxylic acid) is a small organic molecule which accumulates in pipecolic acidemia. It is a ... carboxylic acid of piperidine. It can be associated with some forms of epilepsy. CRYM, a taxon-specific crystallin protein that ...

*Capromorelin

Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs). Discovery of capromorelin. Bioorganic and Medicinal ... Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine growth hormone secretagogue. Endocrine. 2001 ...

*Lithium triethylborohydride

LiBHEt3 also reduces pyridine and isoquinolines to piperidines and tetrahydroisoquinolines respectively. The reduction of β- ...

*Pyridine

Piperidine, a fundamental nitrogen heterocycle, is important synthetic building-block. Piperidines are produced by ... The suggestion by Körner and Dewar was later confirmed in an experiment where pyridine was reduced to piperidine with sodium in ... Burrows, George H.; King, Louis A. (1935). "The Free Energy Change that Accompanies Hydrogenation of pyridines to piperidines ... Hydrogen-saturated piperidine is obtained through reaction with hydrogen gas in the presence of Raney nickel. This reaction ...

*List of dopaminergic drugs

Vanoxerine Piperidines: 1-(1-(1-Benzothiophen-2-yl)cyclohexyl)piperidine (BTCP) • Desoxypipradrol • Dextromethylphenidate • ...

*Clopamide

... (trade name Brinaldix) is a piperidine diuretic. Clopamide is categorised as a thiazide-like diuretic and works in ...

*Dexetimide

... (brand name Tremblex) is a piperidine anticholinergic. It is a muscarinic antagonist that is used to treat drug ...

*Serotonin-norepinephrine-dopamine reuptake inhibitor

Consider the piperidine analogs of brasofensine and tesofensine. These were prepared by NeuroSearch (In Denmark) by the ... CPCA ("nocaine") is the 3R,4S piperidine stereoisomer of (phenyltropane based) RTI-31. It is non addictive, although this might ... "Further SAR studies of piperidine-based analogues of cocaine. 2. Potent dopamine and serotonin reuptake inhibitors". Journal of ... "Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the ...

*List of phenyltropanes

Piperidine homologues had comparable affinity & potency spreads to their respective phenyltropane analogues. Without as much of ... Though front-bridged types were synthesized for the piperidine homologues: the trend of equal values for either isomers of that ... These are namely classes of dopaminergic cocaine analogues that are in the piperidine class (a category that includes ... PubChem CID: 44337825, InChI Key: MHDRABCQAWNSIK-PZORYLMUSA-N Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. ...

*CXCR3

Part 3: Tropenyl and homotropenyl-piperidine urea derivatives". Bioorganic & Medicinal Chemistry Letters. 18 (1): 147-51. doi: ...

*Sodium amide

... will also deprotonate indole and piperidine. It is however poorly soluble in solvents other than ammonia. Its use ...

*Iminosugar

Their piperidine, pyrrolidine, or similar rings are stable. Amino sugar Watson AA, Fleet GW, Asano N, Molyneux RJ, Nash RJ ( ...