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*  Proliferative vitreoretinopathy
These cytokines trigger the ability of the retinal pigmented epithelium (RPE) to proliferate and migrate. The process involved ... TGFβ2 is known to induce EMT in RPE cells and fibrosis in the eye. Expression of PDGF in particular PDGF-AA is triggered during ... TGFβ2 is the most predominant isoform in the eye and is secreted as a latent inactive peptide into the vitreous by epithelial ... The name is derived from proliferation (by the retinal pigment epithelial and glial cells) and vitreo retinopathy to include ...
*  Chromatophore
The exception to this is the melanophores of the retinal pigmented epithelium of the eye. These are not derived from the neural ... Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society ... Humans have only one class of pigment cell, the mammalian equivalent of melanophores, to generate skin, hair, and eye colour. ... When the pigment is aggregated toward the centre of the cell, the pigments in other chromatophores are exposed to light and the ...
*  Bestrophin 1
Bestrophin-1 is an integral membrane protein found primarily in the retinal pigment epithelium (RPE) of the eye. Within the RPE ... The BEST1 gene expresses the Best1 protein primarily in the cytosol of the retinal pigment epithelium. The protein is typically ... localizes to the basolateral plasma membrane of the retinal pigment epithelium". Proceedings of the National Academy of ... researchers are currently working on discovering treatments with stem cell transplants of the retinal pigment epithelium. ...
*  List of MeSH codes (A10)
... epithelium, corneal MeSH A10.272.640 --- pigment epithelium of eye MeSH A10.272.700 --- seminiferous epithelium MeSH A10.272. ...
*  Retinal pigment epithelium
... pigment epithelium of eye at the US National Library of Medicine Medical Subject Headings (MeSH) Histology image: 07902loa - ... The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory ... retinal pigment epithelium hypertrophy and impacted teeth. Bruch's membrane Drusen Macula of retina Fovea centralis Fundus (eye ... Retinal Pigment Epithelium and Macular Diseases. Springer. ISBN 0-7923-5144-4. "eye, human."Encyclopædia Britannica from ...
*  Drusen
... accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. ... In view of their location between the retinal pigment epithelium (RPE) and its vascular supply, the choriocapillaris, it is ... April 2007). "High concentration of zinc in sub-retinal pigment epithelial deposits". Exp. Eye Res. 84 (4): 772-80. doi:10.1016 ... Usually being asymptomatic, drusen are typically found during routine eye exams where the pupils have been dilated. Laser ...
*  Amelanism
Reddish eyes are due to the lack of pigment in the iris pigment epithelium. When the stroma is unpigmented but the iris pigment ... They also have two layers of pigmented tissue in the eye: the stroma, at the front of the iris, and the iris pigment epithelium ... epithelium is not, mammalian eyes appear blue. Melanin in the pigment epithelium is critical for visual acuity and contrast. ... Pigment cells of the iris pigment epithelium have a separate embryological origin. Piebaldism and amelanism are distinct ...
*  Nucleic acid structure
"The effect of light on the quantity of phagosomes in the pigment epithelium". Experimental Eye Research. 23 (6): 623-35. doi: ...
*  Robert MacLaren
The research efforts concentrate on two areas of the eye in particular: the retinal pigment epithelium (RPE), and the ... Eye structure retina retinal pigment epithelium (RPE) photoreceptor cell retinal ganglion cell macula capillary lamina of ... therapy Eye hospitals and institutions in the UK UCL Institute of Ophthalmology Moorfields Eye Hospital Oxford Eye Hospital Eye ... affecting the retinal pigment epithelium (RPE) and causing progressive loss of vision. On 24 November 2011, Mr. Jonathan Wyatt ...
*  2017 in paleontology
2017). Description of the fossilized outer cones, rods, oil droplets and pigment epithelium preserved in an eye of an ... as well as on the impact of the eye size on the eye performance while viewing objects through water and through air is ... 2017). A study on the evolution of eye size in early tetrapods and in fish belonging to the lineage that gave rise to tetrapods ... 2017) report the discovery of eggshell pigments in the eggs of Late Cretaceous oviraptorid ootaxon Macroolithus yaotunensis, ...
*  Eye color
Dissection reveals that the iris pigment epithelium is brownish black due to the presence of melanin. Unlike brown eyes, blue ... The majority of people in the world overall have brown eyes to dark brown eyes. Light or medium-pigmented brown eyes can also ... Other genes implicated in eye color variation are SLC24A4 and TYR. Blue eyes with a brown spot, green eyes, and gray eyes are ... eyes. Blue Eyes Versus Brown Eyes: A Primer on Eye Color. Eyedoctorguide.com. Retrieved on 23 December 2011. Why Do Europeans ...
*  Retina
However it does not pass through the retinal pigment epithelium or the choroid (both of which are opaque). The white blood ... The structures of the eye labeled Another view of the eye and the structures of the eye labeled Illustration of image as 'seen ... "The retinal pigment epithelium". Webvision. Retrieved 1 Jan 2018. Kolb, Helga. "Simple Anatomy of the Retina". Webvision. ... The optic vesicle gives rise to three structures: the neural retina, the retinal pigmented epithelium, and the optic stalk. The ...
*  Membranoproliferative glomerulonephritis
MPGN II can develop drusen which is caused by same deposits within the Bruch's membrane beneath the retinal pigment epithelium ... RPE) layer of the eye. Over time vision can deteriorate and subretinal neovascular membranes, macular detachment, and central ...
*  Albinism
The improper development of the retinal pigment epithelium (RPE), which in normal eyes absorbs most of the reflected sunlight, ... The human eye normally produces enough pigment to color the iris blue, green or brown and lend opacity to the eye. In ... However, when an eye doctor examines the eye by shining a light from the side of the eye, the light shines back through the ... Lack of pigment in the eyes also results in problems with vision, both related and unrelated to photosensitivity. Those ...
*  SLC6A6
"Isolation of a cDNA encoding a taurine transporter in the human retinal pigment epithelium". Curr. Eye Res. 15 (3): 345-9. doi: ... 2006). "Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed ...
*  Maculopathy
It is characterised by changes in pigmentation in the Retinal Pigment Epithelium, the appearance of drusen on the retina of the ... eye and choroidal neovascularization. AMD has two forms; 'dry' or atrophic/non-exudative AMD, and 'wet' or exudative/ ...
*  Human eye
The middle layer, known as the vascular tunic or uvea, consists of the choroid, ciliary body, pigmented epithelium and iris. ... The structures of the eye labeled Another view of the eye and the structures of the eye labeled Anatomy portal Eye color Eye ... The human eye is an organ which reacts to light and pressure. As a sense organ, the mammalian eye allows vision. Human eyes ... Thus, the eye can be considered as undergoing rotations about a single point in the center of the eye. Rapid eye movement, REM ...
*  Eye development
The pigmented retina is formed by rods and cones and composed of small cilia typical of the ependymal epithelium of the neural ... Sagittal section of eye of human embryo of six weeks. Section of developing eye of trout. Ort, D., David, H., "Development of ... Cells from both the mesodermal and the ectodermal tissues contribute to the formation of the eye. Specifically, the eye is ... "Embryonic and Postnatal Development of the Eye". Retrieved 22 April 2015. Fuhrmann, S., "Eye Morphogenesis and Patterning of ...
*  TYRP1
Abe T, Sato M, Tamai M (1998). "Dedifferentiation of the retinal pigment epithelium compared to the proliferative membranes of ... Eye Res. 17 (12): 1103-9. doi:10.1076/ceyr.17.12.1103.5126. PMID 9872531. Commo S, Bernard BA (2000). "Melanocyte subpopulation ... Sarangarajan R, Boissy RE (2001). "Tyrp1 and oculocutaneous albinism type 3". Pigment Cell Res. 14 (6): 437-44. doi:10.1034/j. ... Sarangarajan R, Boissy RE (December 2001). "Tyrp1 and oculocutaneous albinism type 3". Pigment Cell Res. 14 (6): 437-44. doi: ...
*  PEDF
... a pigment epithelium-derived factor with potent neuronal differentiative activity". Experimental Eye Research. 53 (3): 411-4. ... In humans, pigment epithelium-derived factor is encoded by the SERPINF1 gene. Pigment epithelium-derived factor (PEDF) was ... pigment epithelium derived factor), member 1". Steele FR, Chader GJ, Johnson LV, Tombran-Tink J (Feb 1993). "Pigment epithelium ... Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has ...
*  Blood-retinal barrier
The retinal pigment epithelium maintains the outer blood-retinal barrier. Diabetic retinopathy, eye damage that frequently ... The blood retinal barrier has two components: the retinal vascular endothelium and the retinal pigment epithelium. Retinal ...
*  Uveal melanoma
... that reside within the uvea giving color to the eye. These melanocytes are distinct from the retinal pigment epithelium cells ... Louis The Eye Cancer Network Ocular Oncology - Bascom Palmer Eye Institute All NCI-approved clinical trials for uveal melanoma ... Eye. 22 (8): 997-1007. doi:10.1038/sj.eye.6702779. PMID 17384575. van Gils W, Lodder EM, Mensink HW, Kiliç E, Naus NC, ... Uveal melanoma is a cancer (melanoma) of the eye involving the iris, ciliary body, or choroid (collectively referred to as the ...
*  Eye disease
Detachment of retinal pigment epithelium (H35.8) Other specified retinal disorders (H35.81) Macular edema - distorted central ... the tendency for eyes to become cross-eyed (H50.1, H50.3) Exotropia - the tendency for eyes to look outward H52 Disorders of ... Crossed eye/Wandering eye/Walleye) - the eyes do not point in the same direction (H49.3-4) Ophthalmoparesis - the partial or ... a rare congenital eye condition leading to underdevelopment or even absence of the iris of the eye Endophthalmitis Corneal ...
*  National Eye Institute
Some people with LCA have a mutated gene RPE65 that makes a protein found in the retinal pigment epithelium, which is a layer ... National Eye Institute. Harris, RR (1985). "A Brief History of the National Eye Institute". Government Publications Review 12 ( ... Amblyopia, also known as lazy eye, is the most common cause of vision impairment among children. Amblyopia occurs when one eye ... Findings from studies suggest that this characteristic may be similar to how immune cells attack the eye in autoimmune eye ...
*  Vitreous base
The vitreous base is an area in the fundus of the eye in which the vitreous membrane, neural retina, and pigment epithelium all ...
*  Laboratory rat
This mutation results in defective retinal pigment epithelium phagocytosis of photoreceptor outer segments. The shaking rat ... The lack of this organ severely compromises their immune system, infections of the respiratory tract and eye increasing the ...
*  White (horse)
If pigment is missing from both the stroma and the iris pigment epithelium, the only pigment in the eye is the hemoglobin in ... Blue-eyed humans and mammals have little or no pigment in the stroma, but retain pigment in the iris pigment epithelium. ... and in a thin layer at the back of the iris in tissue called the iris pigment epithelium. The iris pigment epithelium prevents ... Many white horses have dark eyes, though some have blue eyes. In contrast to gray horses which are born with pigmented skin ...