Loading...
*  PLCD1
"Entrez Gene: PLCD1 phospholipase C, delta 1". Yagisawa H (2006). "Nucleocytoplasmic shuttling of phospholipase C-delta1: a link ... immunodeficiency virus-1 glycoproteins gp120 and gp160 specifically inhibit the CD3/T cell-antigen receptor phosphoinositide ... 1998). "Phospholipase C-delta1 and oxytocin receptor signalling: evidence of its role as an effector". Biochem. J. 331 (1): 283 ... 1998). "Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss of ...
*  Phosphoinositide phospholipase C
... found in some phospholipases C Phospholipase Zinc-dependent phospholipase C, a different family of phospholipase C Meldrum E, ... Phosphoinositide phospholipase C (PLC) (EC 3.1.4.11, triphosphoinositide phosphodiesterase, phosphoinositidase C, 1- ... Rhee SG, Bae YS (1997). "Regulation of phosphoinositide-specific phospholipase C isozymes". J. Biol. Chem. 272 (24): 15045-8. ... These enzymes belong to a larger superfamily of Phospholipase C. Other families of phospholipase C enzymes have been identified ...
*  Monophosphatidylinositol phosphodiesterase
... an enzyme Phosphoinositide phospholipase C, an enzyme. ...
*  Macropinosome
PI3K and phosphoinositide phospholipase C activation have been shown to be necessary for macropinosome formation in fibroblasts ... in Oncogene-transformed Fibroblasts Depends on Sequential Permanent Activation of Phosphoinositide 3-Kinase and Phospholipase C ...
*  Glycosylphosphatidylinositol phospholipase D
An investigation of the role of endogenous phosphoinositide-specific phospholipases". Biochem. J. 240 (2): 519-527. PMC 1147446 ... glycoprotein phospholipase D, phosphatidylinositol phospholipase D, phosphatidylinositol-specific phospholipase D) is an enzyme ... Phospholipase Low, M.G.; Prasad, A.R.S. (1988). "A phospholipase D specific for the phosphatidylinositol anchor of cell-surface ... Deeg, M.A; Vierman, E.L.; Cheung, M.C. (2001). "GPI-specific phospholipase D associates with an apoA-I- and apoA-IV-containing ...
*  Biochemical cascade
PLCγ (Phosphoinositide Phospholipase C γ) hydrolyzes membrane phospholipids to form IP3 (Inositoltriphosphate) and DAG ( ... Phospholipase C (PLC) is involved in acrosome reaction. ZP3 is a glycoprotein present in zona pelucida and it interacts with ... "Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize ...
*  PLCB1
"Entrez Gene: PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)". Runnels LW, Yue L, Clapham DE (May 2002). "The TRPM7 ... "Nuclear phosphoinositide specific phospholipase C (PI-PLC)-beta 1: a central intermediary in nuclear lipid-dependent signal ... "Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1)". Biochim. Biophys. ... Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu MX (2000). "Association of mammalian trp4 and phospholipase C ...
*  PLCB3
"Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3)". ... "Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1)". Biochim. Biophys. ... "Entrez Gene: PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)". Hwang JI, Heo K, Shin KJ, Kim E, Yun C, Ryu SH, ... Hwang JI, Heo K, Shin KJ, Kim E, Yun C, Ryu SH, Shin HS, Suh PG (2000). "Regulation of phospholipase C-beta 3 activity by Na+/ ...
*  PLCB2
"Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1)". Biochim. Biophys. ... "Entrez Gene: PLCB2 phospholipase C, beta 2". Barr AJ, Marjoram R, Xu J, Snyderman R (Apr 2002). "Phospholipase C-beta 2 ... Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu MX (2000). "Association of mammalian trp4 and phospholipase C ... The gene codes for the enzyme phospholipase C β2. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and ...
*  PLCB4
... "cDNA sequence and gene locus of the human retinal phosphoinositide-specific phospholipase-C beta 4 (PLCB4)". Genomics. 29 (1): ... "Entrez Gene: PLCB4 phospholipase C, beta 4". Cefai D, Debre P, Kaczorek M, et al. (1991). "Human immunodeficiency virus-1 ... Lyu MS, Park DJ, Rhee SG, Kozak CA (1996). "Genetic mapping of the human and mouse phospholipase C genes". Mamm. Genome. 7 (7 ... "Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase ...
*  Prion
... digested by proteinase K and can be liberated from the cell surface in vitro by the enzyme phosphoinositide phospholipase C (PI ...
*  List of EC numbers (EC 3)
... phosphoinositide phospholipase C EC 3.1.4.12: sphingomyelin phosphodiesterase EC 3.1.4.13: serine-ethanolaminephosphate ... EC 3.1.1.1: carboxylesterase EC 3.1.1.2: arylesterase EC 3.1.1.3: triacylglycerol lipase EC 3.1.1.4: phospholipase A2 EC 3.1. ... phospholipase D EC 3.1.4.5: now EC 3.1.21.1 EC 3.1.4.6: now EC 3.1.22.1 EC 3.1.4.7: now EC 3.1.31.1 EC 3.1.4.8: now EC 3.1.27.3 ... N-acetylphosphatidylethanolamine-hydrolysing phospholipase D EC 3.1.5.1: dGTPase EC 3.1.6.1: arylsulfatase EC 3.1.6.2: steryl- ...
*  Gonadotropin-releasing hormone
... a seven-transmembrane G-protein-coupled receptor that stimulates the beta isoform of Phosphoinositide phospholipase C, which ...
*  Ram Rajasekharan
Rupwate, S. D. and R. Rajasekharan (2012) C2 Domain Is Responsible for Targeting Rice Phosphoinositide Specific Phospholipase C ... Ramya, V., and R. Rajasekharan (2016) ATG15 encodes a phospholipase and is transcriptionally regulated by YAP1 in Saccharomyces ... Rupwate, S. D., and R. Rajasekharan (2012) Plant Phosphatidylinositol−Specific Phospholipase C - An insight. Plant Signaling & ... Specific Phospholipase C through the Transcriptional Repression of Upstream Activating Sequence Inositol Containing Genes. FEBS ...
*  PPP1R14B
"Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on ...
*  PLCD4
2004). "The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the ... "Entrez Gene: PLCD4 phospholipase C, delta 4". Cefai D, Debre P, Kaczorek M, et al. (1991). "Human immunodeficiency virus-1 ... 2004). "Phospholipase C δ-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 ... Ghosh S, Pawelczyk T, Lowenstein JM (Jun 1997). "Phospholipase C isoforms delta 1 and delta 3 from human fibroblasts. High- ...
*  Mianserin
Dwivedi Y, Agrawal AK, Rizavi HS, Pandey GN (December 2002). "Antidepressants reduce phosphoinositide-specific phospholipase C ...
*  PLCG2
A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C- ... "Entrez Gene: PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)". Guo B, Kato RM, Garcia-Lloret M, Wahl MI, ... Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble ... Gross BS, Melford SK, Watson SP (1999). "Evidence that phospholipase C-gamma2 interacts with SLP-76, Syk, Lyn, LAT and the Fc ...
*  Phosphatidylinositol phosphate kinases
Characterized and Putative Isoforms of Inositol Phospholipid Kinase and Phosphoinositide-Specific Phospholipase C. Plant ... Analysis of intact phosphoinositides in biological samples. American Soc f Biochem and Mol Biol 2006; 47:1588-1596 Muller- ... Phosphatidylinositol phosphate kinases (PIPK) are kinases that phosphorylate the phosphoinositides PtdInsP and PtdInsP2 that ...
*  Phosphatidylinositol
Characterized and Putative Isoforms of Inositol Phospholipid Kinase and Phosphoinositide-Specific Phospholipase C. Membrane ... Hydrolysis of phosphoinositides yield one mole of glycerol, two moles of fatty acids, one mole of inositol and one, two, or ... Phosphoinositides are regarded as the most acidic phospholipids. The specific fatty acids of PtdIns, and their conformation, ... The most common fatty acids of phosphoinositides are stearic acid in the SN1 position and arachidonic acid, in the SN2 position ...
*  Metabotropic glutamate receptor
Stimulating the receptors causes the associated enzyme phospholipase C to hydrolyze phosphoinositide phospholipids in the ...
*  PX domain
Phospholipase D, and phosphoinositide-3-kinases. The PX domain is structurally conserved in eukaryotes, although amino acid ... The PX domain is a phosphoinositide-binding structural domain involved in targeting of proteins to cell membranes. This domain ... Wishart MJ, Taylor GS, Dixon JE (June 2001). "Phoxy lipids: revealing PX domains as phosphoinositide binding modules". Cell. ... "Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH ...
*  Phagosome
Protein kinase C, phosphoinositide 3-kinase, and phospholipase C (PLC) are all needed for signalling and controlling particle ... In addition, Listeria secrete two phospholipase C enzymes that facilitate in phagosome escape. Autophagosome Phagocyte ...
*  BAG3
"Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic ... "The direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signaling". J ... Pei Z, Maloney JA, Yang L, Williamson JR (September 1997). "A new function for phospholipase C-gamma1: coupling to the adaptor ... Yablonski D, Kadlecek T, Weiss A. "Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 ...
*  VAV1
"Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic ...
*  Rocky Mountain spotted fever
To escape from the phagosome, the bacteria secrete phospholipase D and hemolysin C. This causes disruption of the phagosomal ... CDC42, protein tyrosine kinase, phosphoinositide 3-kinase, and Src-family kinases then activate Arp2/3. This causes the ...
*  PLCG1
"Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic ... "The direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signaling". ... Phospholipase C, gamma 1, also known as PLCG1, is a protein that in humans is encoded by the PLCG1 gene. The protein encoded by ... "Entrez Gene: PLCG1 phospholipase C, gamma 1". Singh SM, Murray D (September 2003). "Molecular modeling of the membrane ...