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*  Phosphatidylinositol
PI 3-kinase Inositol phosphate Phosphatidylinositol 3-phosphate Phosphatidylinositol 4-phosphate Phosphatidylinositol 5- ... P Phosphatidylinositol 5-phosphate, also known as PtdIns5P or PI(5)P Phosphatidylinositol bisphosphates: Phosphatidylinositol 3 ... The phosphatidylinositol can be phosphorylated to form phosphatidylinositol phosphate (PI-4-P, referred to as PIP in close ... The synthesis of phosphatidylinositol in the laboratory is catalyzed by phosphatidylinositol synthase and involves CDP- ...
*  Phosphatidylinositol deacylase
In enzymology, a phosphatidylinositol deacylase (EC 3.1.1.52) is an enzyme that catalyzes the chemical reaction 1-phosphatidyl- ... Other names in common use include phosphatidylinositol phospholipase A2, and phospholipase A2. Gray NC, Strickland KP (1982). " ... of bovine brain acting on phosphatidylinositol". Can. J. Biochem. 60 (2): 108-17. doi:10.1139/o82-015. PMID 7083039. Gray NC, ...
*  Phosphatidylinositol bisphosphate
... may refer to: Phosphatidylinositol (3,4)-bisphosphate Phosphatidylinositol (3,5)-bisphosphate ...
*  Phosphatidylinositol phosphate
... may refer to: Phosphatidylinositol 3-phosphate, also known as PI(3)P Phosphatidylinositol 4- ... phosphate, also known as PI(4)P Phosphatidylinositol 5-phosphate, also known as PI(5)P. ...
*  Phosphatidylinositol transfer protein
... , alpha (PITPNA) Phosphatidylinositol transfer protein, beta (PITPNB) Phosphatidylinositol ... Phosphatidylinositol transfer protein (PITP) or priming in exocytosis protein 3 (PEP3) is a ubiquitous cytosolic domain ... Hay JC, Martin TF (December 1993). "Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca(2+)- ... Hsuan J, Cockcroft S (2001). "The PITP family of phosphatidylinositol transfer proteins". Genome Biol. 2 (9): REVIEWS3011. doi: ...
*  Phosphatidylinositol diacylglycerol-lyase
... phosphatidylinositol phospholipase C, 1-phosphatidylinositol phosphodiesterase, 1-phosphatidyl-D-myo-inositol ... In enzymology, a phosphatidylinositol diacylglycerol-lyase (EC 4.6.1.13) is an enzyme that catalyzes the chemical reaction 1- ... Michell RH, Allan D (1975). "Inositol cyclis phosphate as a product of phosphatidylinositol breakdown by phospholipase C ( ... Low MG, Finean JB (1977). "Release of alkaline phosphatase from membranes by a phosphatidylinositol-specific phospholipase C". ...
*  Phosphatidylinositol 4-phosphate
Phosphatidylinositol 3-phosphate Phosphatidylinositol 5-phosphate Phosphatidylinositol (3,4,5)-trisphosphate Godi A et al., ... Phosphatidylinositol 4-phosphate (PtdIns4P, PI-4-P, PI4P, or PIP) is a precursor of phosphatidylinositol (4,5)-bisphosphate. ... "Lipid Membrane Curvature Induced by Distearoyl Phosphatidylinositol 4-Phosphate". Soft Matter. 8: 3090-3093. doi:10.1039/ ... "Pressure-dependent inverse bicontinuous cubic phase formation in a phosphatidylinositol 4-phosphate/phosphatidylcholine system ...
*  Phosphatidylinositol phosphate kinases
... (PIPK) are kinases that phosphorylate the phosphoinositides PtdInsP and PtdInsP2 that ... The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol Cell 2000 5:1-11. ... Phosphatidylinositol phosphate kinases, a multifaceted family of signalling enzymes. J Biol Chem 1999; 274:9907-9910 Kunz J, ... are derivatives of phosphatidylinositol (PtdIns). It has been found that PtdIns is only phosphorylated on three (3,4,5) of its ...
*  Phosphatidylinositol 3-phosphate
... (PtdIns3P or PI3P) is a phospholipid found in cell membranes that helps to recruit a range of ... It is the product of both the class II and III phosphoinositide 3-kinases (PI 3-kinases) activity on phosphatidylinositol. ... D J Gillooly; A Simonsen; H Stenmark (April 15, 2001). "Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain ...
*  Phosphatidylinositol-3-phosphatase
In enzymology, a phosphatidylinositol-3-phosphatase (EC 3.1.3.64) is an enzyme that catalyzes the chemical reaction 1- ... Lips DL, Majerus PW (1989). "The discovery of a 3-phosphomonoesterase that hydrolyzes phosphatidylinositol 3-phosphate in NIH ... This enzyme participates in inositol phosphate metabolism and phosphatidylinositol signaling system. As of late 2007, two ... "Isolation and characterization of two 3-phosphatases that hydrolyze both phosphatidylinositol 3-phosphate and inositol 1,3- ...
*  Phosphatidylinositol 5-phosphate
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and ... Phosphatidylinositol 4-phosphate and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate). Notably, steady-state PtdIns5P ... Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis. Proc Natl Acad Sci U S A. 2007 ... Phosphatidylinositol 5-phosphate is one of the 7 known cellular phosphoinositides with less understood functions. It is ...
*  Phosphatidylinositol N-acetylglucosaminyltransferase
In enzymology, a phosphatidylinositol N-acetylglucosaminyltransferase (EC 2.4.1.198) is an enzyme that catalyzes the chemical ... Other names in common use include UDP-N-acetyl-D-glucosamine:phosphatidylinositol, N-acetyl-D-glucosaminyltransferase, uridine ... the two substrates of this enzyme are UDP-N-acetylglucosamine and phosphatidylinositol, whereas its two products are UDP and N- ... "Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Origin of ...
*  Phosphatidylinositol a-mannosyltransferase
In enzymology, a phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57) is an enzyme that catalyzes the chemical reaction ... guanosine diphosphomannose-phosphatidyl-inositol, alpha-mannosyltransferase, and phosphatidyl-myo-inositol alpha- ...
*  Phosphatidylinositol 4,5-bisphosphate
... or PtdIns(4,5)P2, also known simply as PIP2 or PI(4,5)P2, is a minor phospholipid ... PIP2 is formed primarily by the type I phosphatidylinositol 4-phosphate 5-kinases from PI(4)P. In metazoans, PIP2 can also be ... "Exploring phosphatidylinositol 5-phosphate 4-kinase function". Adv Biol Regul. 57: 193-202. doi:10.1016/j.jbior.2014.09.007. ... 2005). "Phosphatidylinositol phosphate kinase type Iγ regulates dynamics of large dense-core vesicle fusion". PNAS. 102: 5204- ...
*  Phosphatidylinositol transfer protein, alpha
Phosphatidylinositol transfer protein alpha isoform is a protein that in humans is encoded by the PITPNA gene. ... Phosphatidylinositol transfer proteins are a diverse set of cytosolic phospholipid transfer proteins that are distinguished by ... "Entrez Gene: PITPNA phosphatidylinositol transfer protein, alpha". Wirtz KW (1991). "Phospholipid transfer proteins". Annu. Rev ... "Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca(2+)-activated secretion". Nature. 366 (6455): ...
*  Phosphatidylinositol 3,5-bisphosphate
... defines a novel PI 3-kinase pathway in resting mouse fibroblasts. Biochem J. 1997 May 1; ... Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is one of the seven phosphoinositides found in eukaryotic cell membranes ... PMID 20035756 phosphatidylinositol 3,5-bisphosphate at the US National Library of Medicine Medical Subject Headings (MeSH). ... The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J Cell Sci. ...
*  1-phosphatidylinositol 4-kinase
... phosphatidylinositol 4-kinase, phosphatidylinositol kinase, type II phosphatidylinositol kinase, PI kinase, and PI 4-kinase. ... In enzymology, a 1-phosphatidylinositol 4-kinase (EC 2.7.1.67) is an enzyme that catalyzes the chemical reaction ATP + 1- ... Whitman M, Downes CP, Keeler M, Keller T, Cantley L (1988). "Type I phosphatidylinositol kinase makes a novel inositol ... Kai M, White GL, Hawthorne JN (1966). "The phosphatidylinositol kinase of rat brain". Biochem. J. 101 (2): 328-37. PMC 1270113 ...
*  Phosphatidylinositol 3,4-bisphosphate
Phosphatidylinositol (3,4)-bisphosphate (PtdIns(3,4)P2) is a minor phospholipid component of cell membranes, yet an important ... "Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an ...
*  Phosphatidylinositol transfer protein, cytoplasmic 1
... is a protein that in humans is encoded by the PITPNC1 gene. This gene ... Garner K, Hunt AN, Koster G, Somerharju P, Groves E, Li M, Raghu P, Holic R, Cockcroft S (2012). "Phosphatidylinositol transfer ... Garner K, Li M, Ugwuanya N, Cockcroft S (2011). "The phosphatidylinositol transfer protein RdgBβ binds 14-3-3 via its ... encodes a member of the phosphatidylinositol transfer protein family. The encoded cytoplasmic protein plays a role in multiple ...
*  Phosphatidylinositol-4-phosphate 3-kinase
In enzymology, a phosphatidylinositol-4-phosphate 3-kinase (EC 2.7.1.154) is an enzyme that catalyzes the chemical reaction ATP ... This enzyme participates in phosphatidylinositol signaling system. As of late 2007, 3 structures have been solved for this ...
*  Phosphatidylinositol (3,4,5)-trisphosphate
... (PtdIns(3,4,5)P3), abbreviated PIP3, is the product of the class I phosphoinositide ... Whitman M, Downes CP, Keeler M, Keller T, Cantley L (April 1988). "Type I phosphatidylinositol kinase makes a novel inositol ... phosphatidylinositol 3,4,5 trisphosphate (PIP3) occurs naturally in human neutrophils with levels that increased rapidly ... position of the inositol ring resulting in the formation of phosphatidylinositol-3-phosphate (PI3P). Working independently, ...
*  Phosphatidylinositol 3-kinase-related kinase
... s (PIKKs) are a family of Ser/Thr-protein kinases with sequence similarity to ... phosphatidylinositol-3 kinases (PI3Ks). The human PIKK family includes six members: PIKKs proteins contain the following four ...
*  1-phosphatidylinositol-4-phosphate 5-kinase
In enzymology, 1-phosphatidylinositol-4-phosphate 5-kinase (EC 2.7.1.68) is an enzyme that catalyzes the chemical reaction ATP ... Other names in common use include diphosphoinositide kinase, PIP kinase, phosphatidylinositol 4-phosphate kinase, ... This enzyme participates in 3 metabolic pathways: inositol phosphate metabolism, phosphatidylinositol signaling system, and ... "A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate". Nature. 390 (6656): 192-6. doi:10.1038/36621. PMID ...
*  1-phosphatidylinositol-5-phosphate 4-kinase
In enzymology, a 1-phosphatidylinositol-5-phosphate 4-kinase (EC 2.7.1.149) is an enzyme that catalyzes the chemical reaction ... Rameh LE, Tolias KF, Duckworth BC, Cantley LC (1997). "A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate". ... This enzyme participates in 3 metabolic pathways: inositol phosphate metabolism, phosphatidylinositol signaling system, and ...
*  Phosphatidylinositol-3,4-bisphosphate 4-phosphatase
In enzymology, a phosphatidylinositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) is an enzyme that catalyzes the chemical ... This enzyme participates in inositol phosphate metabolism and phosphatidylinositol signaling system. Howell S, Barnaby RJ, Rowe ...