Plasma half-life of phenformin is 10-15 h. Phenformin protein binding in plasma is about 12-20%.[citation needed] Vladimir ... In Hong Kong, where phenformin is banned, cases of phenformin-induced lactic acidosis occurred after taking Chinese proprietary ... phenformin was still legally available in Italy, Brazil, Uruguay, China, Poland, Greece and Portugal and cases of phenformin- ... Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most ...

Phenformin and buformin are more prone to cause acidosis than metformin; therefore they have been practically replaced by it. ... Initially phenformin was widely used, but its potential for sometimes fatal lactic acidosis resulted in its withdrawal from ... Phenformin. A phenethylated biguanidine. Galega officinalis (French lilac) was used in diabetes treatment for centuries. In the ... Examples include: Metformin - widely used in treatment of diabetes mellitus type 2 Phenformin - withdrawn from the market in ...

Phenformin Rha, Sun Young; Beom, Seung-Hoon; Shin, Young Geun; Yim, Dong-Seok; Moon, Yong Wha; Kim, Tae Won; Kim, Sun Young; ...

Miskimins WK, Ahn HJ, Kim JY, Ryu S, Jung YS, Choi JY (2014). "Synergistic anti-cancer effect of phenformin and oxamate". PLOS ...

Miskimins WK, Ahn HJ, Kim JY, Ryu S, Jung YS, Choi JY (2014). "Synergistic anti-cancer effect of phenformin and oxamate". PLOS ...

Phenformin when administered by itself has a high incidence of lactic acidosis. Due to the inherent ability of oxamate to ... Miskimins WK, Ahn HJ, Kim JY, Ryu S, Jung YS, Choi JY (2014). "Synergistic anti-cancer effect of phenformin and oxamate". PLOS ... Oxamate, as a lactate dehydrogenase (LDH) inhibitor, plus phenformin, an anti-diabetic agent, has been tested in conjunction ... prevent the conversion of pyruvate to lactate, oxamate can be used to counterbalance the side effects of phenformin. Oxamate ...

... , along with phenformin and metformin, inhibits the growth and development of cancer. The anticancer property of these ... Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin ... whereas metformin and phenformin had no statistically significant effect on the carcinogenic process relative to the control ... and phenformin on the post-initiation stage of chemically induced mammary carcinogenesis in the rat". Cancer Prevention ...

March 2022). "Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis". ... Zhang L, He H, Balschi JA (July 2007). "Metformin and phenformin activate AMP-activated protein kinase in the heart by ... The logP of metformin is less than that of phenformin (−0.84) because two methyl substituents on metformin impart lesser ... G. officinalis itself does not contain any of these medications, but isoamylene guanidine; phenformin, buformin, and metformin ...

Pharmaceutical drugs that are substituted phenethylamines include phenelzine, phenformin, and fanetizole, among many others. ...

Phenformin was marketed under the name "DBI" until it was taken off the market after being linked to increased incidence of ... The compound, with the generic name Phenformin was, after exhaustive clinical evaluation, finally chosen. After approval by the ...

The older related and now withdrawn drug phenformin carried a much higher risk of lactic acidosis. Isoniazid toxicity Propofol ... Fimognari, F. L.; Pastorelli, R.; Incalzi, R. A. (2006). "Phenformin-Induced Lactic Acidosis in an Older Diabetic Patient: A ... recurrent drama (phenformin and lactic acidosis)". Diabetes Care. 29 (4): 950-1. doi:10.2337/diacare.29.04.06.dc06-0012. PMID ...

... phenformin, and AICAR". American Journal of Physiology. Endocrinology and Metabolism. 287 (2): E310-7. doi:10.1152/ajpendo. ...

Phenformin (DBI) was used from 1960s through 1980s, but was withdrawn due to lactic acidosis risk. Buformin also was withdrawn ... Fimognari FL, Pastorelli R, Incalzi RA (April 2006). "Phenformin-induced lactic acidosis in an older diabetic patient: a ... recurrent drama (phenformin and lactic acidosis)". Diabetes Care. 29 (4): 950-951. doi:10.2337/diacare.29.04.06.dc06-0012. PMID ...

These are divided into: (1) diabetes, liver disease, and other serious diseases (2) phenformin, fructose, and other drugs (3) ...

... which also included phenformin and buformin (both discontinued). G. officinalis contains the phytochemicals, galegine and ...

When comparing LD50 values for 6 common drugs: acetaminophen, amiodarone, diclofenac, metformin, phenformin, and valproic acid ...

... and their subunit CD147/BASIGIN sensitizes glycolytic tumor cells to phenformin », Cancer Res, (2015) 75, p. 171-80 Cormerais Y ...

One of the more recent discoveries made by Herlyn's lab found that the diabetes drug phenformin could be used to treat certain ...

The molecular formula C10H15N5 (molar mass: 205.26 g/mol, exact mass: 205.1327 u) may refer to: Phenformin Trapidil This set ...

... phenformin MeSH D02.078.370.200 - cimetidine MeSH D02.078.370.280 - creatine MeSH D02.078.370.380 - gabexate MeSH D02.078. ...

... phenformin, orabolin and warfarin. On his return to Greece, in 1981, he was appointed consultant cardiologist and director of ...

... phenformin (INN) phenglutarimide (INN) phenicarbazide (INN) phenindamine (INN) phenindione (INN) pheniodol sodium (INN) ...

A10BA01 Phenformin A10BA02 Metformin A10BA03 Buformin A10BB01 Glibenclamide A10BB02 Chlorpropamide A10BB03 Tolbutamide A10BB04 ... A10BB10 Metahexamide A10BB11 Glisoxepide A10BB12 Glimepiride A10BB31 Acetohexamide A10BC01 Glymidine A10BD01 Phenformin and ...

... a database interface for Perl Phenformin, by the trade name DBI This disambiguation page lists articles associated with the ...

The initial phenformin was withdrawn worldwide (in the U.S. in 1977) due to its potential for sometimes fatal lactic acidosis ...