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*  Hyperalgesia
... in rats after spinal nerve injury and inflammation". Eur. J. Pharmacol. 510 (3): 223-8. doi:10.1016/j.ejphar.2005.01.033. PMID ... which may be caused by damage to nociceptors or peripheral nerves. Prostaglandins E and F are largely responsible for ... tactile pain associated with nerve injury". Eur. J. Neurosci. 23 (4): 995-1004. doi:10.1111/j.1460-9568.2006.04623.x. PMID ... Hyperalgesia is similar to other sorts of pain associated with nerve irritation or damage such as allodynia and neuropathic ...
*  Nerve injury
Usually, however, (peripheral) nerve injury is classified in five stages, based on the extent of damage to both the nerve and ... In 1941, Seddon introduced a classification of nerve injuries based on three main types of nerve fiber injury and whether there ... and nerve reinnervation. The events that occur in peripheral regeneration occur with respect to the axis of the nerve injury. ... The study of peripheral nerve injury began during the American Civil War and has greatly expanded to the point of using growth- ...
*  Neuroregeneration
Sema 3A (Semaphorin 3A) is present in the scar that forms in both central nervous system and peripheral nerve injuries and ... This is called peripheral nerve reconstruction. The injured nerve is identified and exposed so that normal nerve tissue can be ... like injury to bone, muscle and skin, can make nerve recovery more difficult. The level of injury: After a nerve is repaired, ... The mechanism of injury: Sharp injuries, such as a knife wound, damage only a very short segment of the nerve, availing for ...
*  Neuropathic pain
... chemotherapy-induced peripheral neuropathy), radiation injury or surgery. After a peripheral nerve lesion, aberrant ... Peripheral nerve injury induces glia to release proinflammatory cytokines and glutamate-which, in turn influence neurons. The ... Neuropathic pain is common in cancer as a direct result of cancer on peripheral nerves (e.g., compression by a tumor), or as a ... Other mechanisms may take place at the central level after peripheral nerve damage. The loss of afferent signals induces ...
*  Peripheral nerve injury classification
Nerve Nerve fiber Peripheral nerve injury (Nerve injury) Connective tissue in the peripheral nervous system Neuroregeneration ... "Peripheral Nerve Injuries". "Seddon classification of nerve injuries". Otto D.Payton & Richard P.Di Fabio et al.Manual of ... Classification of peripheral nerve injury assists in prognosis and determination of treatment strategy. Classification of nerve ... It is the mildest type of peripheral nerve injury. There are sensory-motor problems distal to the site of injury. The ...
*  Radial tunnel syndrome
ISBN 978-0-387-76599-0. Russell, Stephen M. (2006). "Radial Tunnel Syndrome". Examination of peripheral nerve injuries: an ... The term "radial tunnel syndrome" is used for compression of the posterior interosseous nerve, a division of the radial nerve, ... since the posterior interosseous nerve mainly affects motor function. This problem is often caused by: bone tumors, injury ( ... Nerve and Vascular Injuries in Sports Medicine. Berlin: Springer. pp. 79-80. ...
*  Brachial plexus
Injuries associated with malpositioning commonly affect the brachial plexus nerves, rather than other peripheral nerve groups. ... the axillary nerve, the radial nerve, the median nerve, and the ulnar nerve. Due to both emerging from the lateral cord the ... Brachial plexus injuries are injuries that affect the nerves that carry signals from the spine to the shoulder. This can be ... Journal of Brachial Plexus and Peripheral Nerve Injury. Retrieved 12/2/15. Check date values in: ,access-date= (help) Cunnane, ...
*  Lumbosacral plexus
Journal of Brachial Plexus and Peripheral Nerve Injury. 9 (1). doi:10.1186/1749-7221-9-1. [permanent dead link] Atlas image: ... The anterior divisions of the lumbar nerves, sacral nerves, and coccygeal nerve form the lumbosacral plexus, the first lumbar ... lumbar plexus sacral plexus pudendal plexus Injuries to the lumbosacral plexus are predominantly witnessed as bone injuries. ... Lumbosacral trunk and sacral plexus palsies are common injury patterns. This article incorporates text in the public domain ...
*  ZNRF1
Araki T, Nagarajan R, Milbrandt J (2001). "Identification of genes induced in peripheral nerve after injury. Expression ... In a study identifying genes in rat that are upregulated in response to nerve damage, a gene which is highly expressed in ...
*  Neuronal lineage marker
The reorganization and migration of calbindin-stained Purkinje neurons in rat cerebellum after peripheral nerve injury suggests ... Rusanescu, G.; Mao, J. (2016). "Peripheral nerve injury induces adult brain neurogenesis and remodeling". Journal of Cellular ... An ideal marker is specific to a given cell type in normal conditions and/or during injury. Cell markers are very valuable ... or to any of the differentiated cell types found in the central and peripheral nervous systems (inhibitory and excitatory ...
*  Cerebellum
Rusanescu G, Mao J (2016). "Peripheral nerve injury induces adult brain neurogenesis and remodeling". Journal of Cellular and ... CS1 maint: Uses authors parameter (link) Rusanescu, G.; Mao, J. (2016). "Peripheral nerve injury induces adult brain ... Calbindin staining of rat brain after unilateral chronic sciatic nerve injury suggests that Purkinje neurons may be newly ... Underneath the gray matter of the cortex lies white matter, made up largely of myelinated nerve fibers running to and from the ...
*  P2RX7
These receptors are upregulated in response to peripheral nerve injury. In melanocytic cells P2X7 gene expression may be ... The receptor is found in the central and peripheral nervous systems, in microglia, in macrophages, in uterine endometrium, and ... Russo MV, McGavern DB (October 2015). "Immune Surveillance of the CNS following Infection and Injury". Trends Immunol. 36 (10 ... "Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems". J. Neurosci. 21 ( ...
*  Erythropoietin in neuroprotection
... response after neurological trauma also points to initial stimulation of nerve regeneration after peripheral nerve injury. ... and at increased levels in Schwann cells after peripheral nerve injury. The distribution of EpoR was different from Epo, ... it is apparent that erythropoietin has anti-apoptotic action after central and peripheral nerve injury. Cross-talk between JAK2 ... "The role of erythropoietin in central and peripheral nerve injury". Clin Neurol Neurosurg. 109 (8): 639-44. doi:10.1016/j. ...
*  Professional Medical Film
Peripheral Nerve Surgery - Part I: Sciatic Nerve; Management of typical peripheral nerve injury case of WW II; follow-up ... The Diagnosis of Peripheral Nerve Injuries; Significant clinical findings of 12 cases of various nerve injuries (16 min; color ... Method of Repair of Posterior Tibial Nerve; Repairing long defects in peripheral nerve; bridging large gap in tibial nerve by ... Peripheral Nerve Injuries (16 min). PMF 5054 - PMF 5055 - PMF 5056 (1947) - Therapeutic Exercise, Thoracic Surgery; Physical ...
*  Somatosensory rehabilitation of pain
In H.-J. Seddon (Ed.), Peripheral Nerve Injuries (pp. 354-388). London, England: Her Majesty's Stationery Office. Medical ... In 1981, he published his first Textbook about the testing after nerve injury and repair and was the first to propose a re- ... In other words, after a peripheral nerve lesion, aberrant sprouting occurs in the dorsal horn which can explain that a non- ... This hypersensitivity to touch is induced by the peripheral nerve lesion of the large myelinated A-beta fibers. ...
*  Elspeth McLachlan
McLachlan, E.M. and Hu, P. (2014) Inflammation in Dorsal Root Ganglia After Peripheral Nerve Injury: Effects Of The Sympathetic ... McLachlan, EM; Jänig, W; Devor, M; Michaelis, M. "Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ... particularly injuries to peripheral nerves and the spinal cord. McLachlan was born in Bowral, New South Wales, Australia. ... Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature, Lond. 363, 543-546 Jänig, W. and ...
*  Cryoneurolysis
Burnett (2004). "Pathophysiology of peripheral nerve injury: a brief review". Neurosurgical Focus. 16 (5): E1. doi:10.3171/foc. ... "Three Types of Nerve Injury". Brain. 66 (4): 238-288. doi:10.1093/brain/66.4.237. Savastano (2014). "Sciatic nerve injury: A ... Sunderland (1951). "A classification of peripheral nerve injuries producing loss of function". Brain. 74 (4): 491-516. doi: ... Sunderland (1968). Nerves and Nerve Injuries. Edinburgh & London: Livingstone. p. 180. Zhou (2003). "Cryoanalgesia: ...
*  AxoGen
The company reports recovery in 87 percent of patients with peripheral nerve injuries. AxoGen is part of the Sid Martin ... AxoGen is a human tissue company based in Alachua, Florida making products to remedy peripheral nerve damage. In 2013 the ... Nerve allograft Graft Helps Nerves Regrow; More Patients Avoid Amputation Through Technique Based on Cadaver Implant December ... AxoGen uses a cell graft technology AVANCE to mimic a human nerve. ...
*  Endoneurium
... thereby assisting in locating injuries to peripheral nerves. The endoneurium runs longitudinally along the nerve fiber, but ... Peripheral nerve injuries commonly release increased amounts of endoneurial fluid into surrounding tissues; these can be ... Connective tissue in the peripheral nervous system Epineurium Nerve fascicle Nerve fiber Perineurium Elaine N. Marieb and Katja ... The endoneuria with their enclosed nerve fibers are bundled into groups called nerve fascicles, each fascicle within its own ...
*  Rostral ventromedial medulla
Spinal ondansetron also reversed allodynia and hyperalgesia caused by a peripheral nerve injury. Taken together, these findings ... This suggests that the RVM contributes to the persistent pathology caused by nerve injury. Further research determined that a ... Injection of the CCK-saporin conjugate also reversed allodynia and hyperalgesia in a nerve injury model, producing the same ... In addition, lidocaine microinjections into the RVM temporarily reversed allodynia and hyperalgesia caused by nerve injury. To ...
*  VUF-8430
"Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury". Neuroimmunomodulation. 14 ...
*  Henry Head
Brain, 1905, 28, 362.) With J. Sherren: The consequences of injury to the peripheral nerves in man. (Brain, 1905, 28, 116-338 ... Beginning by examining patients in whom nerves had been divided, Head and his co-worker J. Sherren soon realised the folly in ... The regeneration of these nerves was charted over the next four years. Every Friday, Head would travel to Rivers' rooms in St ... In April 1903 an operation was performed by Sherren to divide two cutaneous nerves in Head's left forearm: the radial and the ...
*  Platelet-rich plasma
A Promising Product for Treatment of Peripheral Nerve Regeneration After Nerve Injury". Int J Neurosci. 121 (4): 176-180. doi: ... Injury. 40 (2): 158-62. doi:10.1016/j.injury.2008.06.025. PMID 19084836. Esposito M (Spring 2010). "Effectiveness of sinus lift ... PRP has received attention in the popular media as a result of its use in treating sports injuries in professional athletes. ... Platelet-rich plasma is used in horses for treatment of equine lameness due to tendon and ligament injury, wounds, fractures, ...
*  Carcinogenesis
"Role of IL-10 in Resolution of Inflammation and Functional Recovery after Peripheral Nerve Injury". The Journal of Neuroscience ... "CCL2 Mediates Neuron-Macrophage Interactions to Drive Proregenerative Macrophage Activation Following Preconditioning Injury". ... progenitor cells from adipose-derived stem cells to preserve neurovascular structures in rat hypoxic-ischemic brain injury". ...
*  Honor Smith
She then moved to Oxford, where she worked for Herbert Seddon's peripheral nerve injury unit. She began working for Hugh ...
*  CD34
... malignant peripheral nerve sheath tumors, mengingeal hemangiopericytomas, meningiomas, neurofibromas, schwannomas, and ... Research has shown that CD34+ cells are relatively more in men than in women in the reproductive age among Spinal Cord Injury ... Ruiz ME, Cicala C, Arthos J, Kinter A, Catanzaro AT, Adelsberger J, Holmes KL, Cohen OJ, Fauci AS (Oct 1998). "Peripheral blood ... Injection of CD34+ hematopoietic Stem Cells has been clinically applied to treat various diseases including Spinal Cord Injury ...
*  Pauls Stradiņš
Under Fedorov's supervision, Stradiņš completed a doctoral thesis on the treatment of peripheral nerve injury. It included data ... At the end of the 1920s, Stradiņš turned his attention from peripheral neurosurgery to abdominal surgery and cancer treatment. ... and his works on the spontaneous gangrene and operations on nerves as indubitably excellent".[citation needed] Stradiņš ... from 862 patients on trophic, secretory and vasomotor disturbances after injuries to the extremities, and on surgical and ...