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*  Peptide nucleic acid
Peptide synthesis Oligonucleotide synthesis Glycol nucleic acid Threose nucleic acid Clicked peptide polymer Nielsen PE, Egholm ... Peptide nucleic acid (PNA) is an artificially synthesized polymer similar to DNA or RNA. It was invented by Peter E. Nielsen ( ... June 2006). "Peptide Nucleic Acid (PNA): A Review". Journal of Chemical Technology and Biotechnology. An overview of the PNA ... Synthetic peptide nucleic acid oligomers have been used in recent years in molecular biology procedures, diagnostic assays, and ...
*  Morpholino
"Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules." eds. Janson & During (Springer, 2007) Moulton, Jon ( ... Oligonucleotide synthesis Nucleic acid analogue Summerton, J (1999). "Morpholino Antisense Oligomers: The Case for an RNase-H ... Current Protocols in Nucleic Acid Chemistry. New Jersey: John Wiley & Sons, Inc. ISBN 978-0-471-24662-6. ... Usually 25 bases in length, they bind to complementary sequences of RNA or single-stranded DNA by standard nucleic acid base- ...
*  MiR-155
"Efficient inhibition of miR-155 function in vivo by peptide nucleic acids". Nucleic Acids Research. 38 (13): 4466-75. doi: ... Hu YL, Fong S, Largman C, Shen WF (Sep 2010). "HOXA9 regulates miR-155 in hematopoietic cells". Nucleic Acids Research. 38 (16 ... Hu YL, Fong S, Largman C, Shen WF (Sep 2010). "HOXA9 regulates miR-155 in hematopoietic cells". Nucleic Acids Research. 38 (16 ... Griffiths-Jones S (Jan 2004). "The microRNA Registry". Nucleic Acids Research. 32 (Database issue): D109-11. doi:10.1093/nar/ ...
*  Nucleic acid templated chemistry
Gorska K, Huang KT, Chaloin O, Winssinger N (April 2009). "DNA-templated homo- and heterodimerization of peptide nucleic acid ... "DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes". J. Am. Chem. Soc. 130 (14): 4646- ... Nucleic acid templated chemistry (NATC), or DNA-templated chemistry, is a tool used in the controlled synthesis of chemical ... Pianowski Z, Gorska K, Oswald L, Merten CA, Winssinger N (May 2009). "Imaging of mRNA in live cells using nucleic acid- ...
*  Sequence-controlled polymer
At first, taking DNA or RNA as templates, scientists developed a series of peptide nucleic acid (PNA)-based polymers, without ... "DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes". Journal of the American Chemical ... Through precise sequences of DNA, 20 amino acids are able to generate sequential peptide chains with three-dimensional ... which can be used to synthesize peptides consisted of natural and non-natural amino acids. In this method, the monomers are ...
*  RNA world
... pre-RNA nucleic acids have included peptide nucleic acid (PNA), threose nucleic acid (TNA) or glycol nucleic acid (GNA). ... A candidate nucleic acid is peptide nucleic acid (PNA), which uses simple peptide bonds to link nucleobases. PNA is more stable ... Threose nucleic acid (TNA) has also been proposed as a starting point, as has glycol nucleic acid (GNA), and like PNA, also ... Peptide bond formation The ability to catalyse the formation of peptide bonds between amino acids to produce short peptides or ...
*  History of Earth
Nelson, K.E.; Levy, M. & Miller, S.L. (April 2000). "Peptide nucleic acids rather than RNA may have been the first genetic ... Nucleic acids such as RNA might then have formed more easily within the liposomes than they would have outside. Some clays, ... Amino acids, the building blocks of proteins, are easily synthesized in plausible prebiotic conditions, as are small peptides ( ... The earliest ribozymes may have been formed of simpler nucleic acids such as PNA, TNA or GNA, which would have been replaced ...
*  Abiogenesis
... certain reactions of condensation-dehydration of amino acids and nucleotides in individual blocks of peptides and nucleic acids ... Nelson, Kevin E.; Levy, Matthew; Miller, Stanley L. (11 April 2000). "Peptide nucleic acids rather than RNA may have been the ... amino acids (protein metabolism), and nucleic acids (self-replicating DNA and RNA). Any successful theory of abiogenesis must ... that provide essential precursors for nucleic acids, amino acids and lipids. A study at the University of Düsseldorf created ...
*  Evolutionary history of life
Nelson, Kevin E.; Levy, Matthew; Miller, Stanley L. (April 11, 2000). "Peptide nucleic acids rather than RNA may have been the ... Nucleic acids such as RNA might then have formed more easily within the liposomes than they would have outside. RNA is complex ... The earliest "ribozymes" may have been formed of simpler nucleic acids such as PNA, TNA or GNA, which would have been replaced ... Although they are not intrinsically information-carriers as nucleic acids are, they would be subject to natural selection for ...
*  Spatiotemporal gene expression
Negatively Charged Peptide Nucleic Acids". Journal of the American Chemical Society. 129 (36): 11000-11001. doi:10.1021/ ... Alexander Heckel, Günter Mayer, "The Chemical Biology of Nucleic Acids", Chapter 13. Light-Responsive Nucleic Acids for the ... In situ hybridization is an alternate method in which a "probe," a synthetic nucleic acid with a sequence complementary to the ... of gene expression has been performed in cell monolayer and in zebrafish embryos using caged morpholino or peptide nucleic acid ...
*  Guillermo Bazan
DNA Detection using Water-Soluble Conjugated Polymers and Peptide Nucleic Acid Probes, Gaylord, B.S.; Heeger, A.J.; Bazan, G.C ...
*  Triple-stranded DNA
In peptide nucleic acid (PNA), the sugar-phosphate backbone is replaced with a protein-like backbone. PNAs form P-loops while ... Watson, J. D.; Crick, F. H. C. (1953). "Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid". Nature ... Using nucleic acid segments that bind to the DNA duplexes to form triple strands as a way of regulating gene expression is ... Soyfer, Valery N.; Potaman, Vladimir N. (1995). Triple-Helical Nucleic Acids. New York: Springer. ISBN 978-0-387-94495-1. Mills ...
*  MiR-122
... peptide nucleic acids (PNA), and PNA-peptide conjugates". RNA. 14 (2): 336-46. doi:10.1261/rna.844108. PMC 2212241 . PMID ... Santaris Pharma are developing miravirsen, a locked nucleic acid-based antisense oligonucleotide that is delivered to the liver ... Nucleic Acids Res. 41 (7): 4230-40. doi:10.1093/nar/gkt075. PMC 3627571 . PMID 23416544. Page for mir-122 precursor family at ... Nucleic Acids Res. 36 (4): 1153-62. doi:10.1093/nar/gkm1113. PMC 2275095 . PMID 18158304. Castoldi, Mirco; Vujic Spasic, Maja, ...
*  Threose nucleic acid
Oligonucleotide synthesis Abiogenesis Glycol nucleic acid Peptide nucleic acid Yu, Hanyang; Zhang, Su; Chaput, John C. (10 ... Threose nucleic acid (TNA) is an artificial genetic polymer invented by Albert Eschenmoser. TNA has a backbone structure ... Was simple TNA the first nucleic acid on Earth to carry a genetic code?, New Scientist (behind paywall) ORIGIN OF LIFE: A ... Schoning, K; Scholz P; Guntha S; Wu X; Krishnamurthy R; Eschenmoser A (November 2000). "Chemical etiology of nucleic acid ...
*  Wang tile
have shown that these tiles can also be composed of peptide nucleic acid (PNA), a stable artificial mimic of DNA. Wang tiles ... have demonstrated the feasibility of creating molecular "tiles" made from DNA (deoxyribonucleic acid) that can act as Wang ...
*  Urticaria pigmentosa
2003). "One-Step Detection of c-kit Point Mutations Using Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping and ... Another mast cell stabilizer Gastrocrom, a form of cromoglicic acid has also been used to reduce mast cell degranulation. ... The majority of urticaria pigmentosa cases are caused by a point mutation at amino acid 816 of the proto-oncogene c-kit. c-kit ...
*  Nuclear magnetic resonance spectra database
Peptides, Nucleic Acids, and other Biomolecules. It stores a large variety of raw NMR data. Bio-Rad Laboratories specializes in ...
*  AEG (disambiguation)
... a backbone molecule of peptide nucleic acids. ...
*  Robert C. Kolodny
... a biotechnology company specializing in peptide nucleic acids. Kolodny co-authored 16 books for both professional and lay ... Bauman, J.E., Kolodny, R.C., and Webster, S.K., "Vaginal organic acids and hormonal changes in the menstrual cycle", Fertility ... short chain aliphatic fatty acids) in human vaginal secretions that serve as pheromones in other mammalian species Dr. Kolodny ...
*  Diamino acid
Diamino acids are used for the synthesis of specific peptide nucleic acids, such as daPNA. Artificial peptide nucleic acids are ... Diamino acids belong to the class of amino acids. Asparagine, glutamine and lysine are proteinaceous diamino acids which are ... Ornithine and 2,6-diaminopimelic acid are non-proteinaceous diamino acids. In biochemistry, diamino acids are of particular ... These three diamino acids are coded by codons of the genetic material and belong therefore to the cationic amino acids. ...
*  Antisense therapy
Oligonucleotide synthesis Antisense Antisense mRNA Morpholino Peptide nucleic acid Locked nucleic acid RNA interference (which ... This synthesized nucleic acid is termed an "anti-sense" oligonucleotide (AON) because its base sequence is complementary to the ... Additionally, most targets of antisense are located inside cells, and getting nucleic acids across cell membranes is also ... it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue) that will bind to the messenger RNA ( ...
*  David Zarling
2002 Nov;80(5):543-51 Belotserkovskii BP, Zarling DA (March 2002). "Peptide nucleic acid (PNA) facilitates multistranded hybrid ...
*  PNA
Peanut agglutinin, a lectin specific for Gal-β(1-3)-GalNAc Peptide nucleic acid, an artificially synthesized polymer similar to ...
*  Candida bracarensis
"Candida bracarensis Detected among Isolates of Candida glabrata by Peptide Nucleic Acid Fluorescence In Situ Hybridization: ...
*  13 Things That Don't Make Sense
Peptide nucleic acid, into soap molecules and heat them up; and the work of the Institute for Complex Adaptive Matter at the ...
*  Phage display
Peptides are usually fused to the N-terminus of pVIII. Usually peptides that can be fused to pVIII are 6-8 amino acids long. ... Nucleic Acids Res. 34 (21): e145. doi:10.1093/nar/gkl772. PMC 1693883 . PMID 17088290. Lunder M, Bratkovič T, Urleb U, Kreft S ... Castillo J, Goodson B, Winter J (November 2001). "T7 displayed peptides as targets for selecting peptide specific scFvs from ... Nucleic Acids Res. 40 (Database issue): D271-7. doi:10.1093/nar/gkr922. PMC 3245166 . PMID 22053087. Negi SS, Braun W (2009). " ...