The Crotamine gene was the first gene to be mapped on a snake chromosome. The gene responsible for coding the crotamine protein ... Exon 1 codes for the first 19 amino acids of the signal peptide and includes the 5'-untranslated region. Exon 2 codes 39 amino ... The mRNA has about 340 nucleotides and codifies a pre-crotamine, including the signal peptide, the mature crotamine, and a ... CS1 German-language sources (de), Peptides, Vertebrate toxins, Ion channel toxins). ...

This gene maps in close proximity to defensin family member defensin, alpha 1, and has been implicated in the pathogenesis of ... Valore EV, Park CH, Quayle AJ, Wiles KR, McCray PB, Ganz T (April 1998). "Human beta-defensin-1: an antimicrobial peptide of ... Ali RS, Falconer A, Ikram M, Bissett CE, Cerio R, Quinn AG (July 2001). "Expression of the peptide antibiotics human beta ... Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly ...

Salomon DS, Brandt R, Ciardiello F, Normanno N (July 1995). "Epidermal growth factor-related peptides and their receptors in ... Erk-family MAP kinases, the Ca2+ /calmodulin-dependent protein kinase II (CamKII) and protein kinase C (PKC). Smad7 does not ... The linker region contains important regulatory peptide motifs including potential phosphorylation sites for mitogen-activated ...

Not only can photo-methionine be used for mapping 3D protein structure, studying protein-protein interactions, but now ... Kölbel, Knut; Ihling, Christian H.; Sinz, Andrea (2012). "Analysis of Peptide Secondary Structures by Photoactivatable Amino ... from chymotryptic peptides) that were composed of photo-cyt b5 and cytochrome P450 in molecular weight ratio's of 1:1, 1:2, and ... and laminin γ1 short arm to see if this photo-cross linking method could map out the structure. MS/MS analysis was done before ...

It had 10716 peptides grouped into 1229 sets. These peptides were extracted from biopanning results of phage-displayed random ... As the mimic of binding site, mimotope analysis has been widely used in mapping epitopes, identifying drug target and inferring ... Mimotopes are a kind of peptide aptamers. When the term mimotope was first coined by Mario Geysen in 1986, it was used to ... A mimotope is often a peptide, and mimics the structure of an epitope. Because of this property it causes an antibody response ...

Dahan I, Issaeva I, Gorzalczany Y, Sigal N, Hirshberg M, Pick E (Mar 2002). "Mapping of functional domains in the p22(phox) ... "NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide". ... subunit of flavocytochrome b(559) participating in the assembly of the NADPH oxidase complex by "peptide walking"". The Journal ... "Topology of cytochrome b558 in neutrophil membrane analyzed by anti-peptide antibodies and proteolysis". The Journal of ...

... peptide and protein - ion interactions. IBIS also allows the mapping of a biomolecular interaction network for any given ...

... and mapped critical domains of class I Major Histocompatibility Complex molecules necessary for presenting viral peptides to ...

Analysis of the MACPF domain structures reveals that these sequences map to the second cluster of helices that unfurl to span ... "Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: ... Biochemical studies have revealed the peptide sequences in C8α and C9 that bind to CD59. ...

RS1 also plays a role in the regulation on intracellular MAP kinase signalling. The retinoschisin monomer is 224 amino acids ... long, including a 23-amino acid signal peptide essential for secretion (this is cleaved off before the protein becomes ...

By associating m/z with positions where they are acquired, unique ion maps of analytes can be generated, which provides ... The ESI-like process enabled MALDESI to detect multiply charged peptides and proteins, which could not be realized by MALDI ... IR-MALDESI is an ablation-based technique, which is able to measure and generate 3D heat maps of biomolecules from ... "Mapping Antiretroviral Drugs in Tissue by IR-MALDESI MSI Coupled to the Q Exactive and Comparison with LC-MS/MS SRM Assay". ...

Neuropeptide Y (endogenous agonist, non subtype selective) BWX-46 (selective NPY5 agonist, CAS# 172997-92-1) Peptide YY CGP- ... "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not ... clustered with receptors specific for neuropeptide Y and peptide YY". Genomics. 46 (2): 287-90. doi:10.1006/geno.1997.5024. ...

Keire DA, Bowers CW, Solomon TE, Reeve JR (February 2002). "Structure and receptor binding of PYY analogs". Peptides. 23 (2): ... "Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not ... Pancreatic polypeptide Neuropeptide Y (endogenous agonist, non subtype selective) Peptide YY GR-231,118 (mixed NPY1 antagonist ... and peptide YY". The Journal of Biological Chemistry. 270 (45): 26762-26765. doi:10.1074/jbc.270.45.26762. PMID 7592911. Yan H ...

October 2003). "Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell ... His research also has discovered alternate sentinel lymph node mapping possibilities and opportunities to avoid axillary ... peptide-pulsed dendritic cell vaccines in a variety of ways. ...

Using restriction mapping and sequencing, the gene was found to have these domains which spanned over three exons with two ... Exon A encodes a putative signal peptide, the arginine vasopressin hormone, and the N terminus of the NP carrier protein. Exon ... AVP and other AVP-like peptides are found in mammals, as well as mollusks, arthropods, nematodes, and other invertebrate ... The researchers used restriction mapping and nucleotide sequence analysis to uncover the gene's three distinct exons and the ...

A two-dimensional map is created using this technique that can be used to match additional proteins later. One can usually ... A peptide mixture was made by washing off unbound portions of the amino acid sequence in a reverse column. The resulting ... So far, only small subsets of the neuronal proteome have been mapped, and then only when applied to the proteins involved in ... Not only does the field have to map out the different proteins possible from the genome, but there are many modifications that ...

doi:10.1016/j.peptides.2015.04.017. PMID 25929172. S2CID 17846143. Shafee T, Anderson MA (March 2019). "A quantitative map of ... Defensin mimetics, also called host defense peptide (HDP) mimetics, are completely synthetic, non-peptide, small molecule ... Peptides. 27 (11): 2614-23. doi:10.1016/j.peptides.2006.06.010. PMID 16914230. S2CID 21104756. Varkey J, Nagaraj R (November ... Host defense peptides, to which defensins belong Hazlett L, Wu M (January 2011). "Defensins in innate immunity". Cell and ...

Inhibition of ACKR3 by ligands such as the peptide LIH383 (FGGFMRRK-NH2) increases opioid peptide activity and produces ... Libert F, Passage E, Parmentier M, Simons MJ, Vassart G, Mattei MG (September 1991). "Chromosomal mapping of A1 and A2 ... This GPCR protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP) and was considered to be an ... Another study has provided evidence that ligand binding to CXCR7 activates MAP kinases through Beta-arrestins, and thus has ...

They mapped the interaction of HMGA1a and the paired homeodomain motif within Crx and showed that these interactions help ... that fusion proteins between HMGA2 and other C terminal peptides (following chromosomal translocation) can drive the ... Using a number of recombinant and congenic rat strains, the work mapped susceptibility genes in the BB rat to the class II MHC ... Ono SJ; Song Z (March 1995). "Mapping of the interaction site of the defective transcription factor in the class II major ...

They have also mapped circuits that link the clock to behavioral activity. Seeking to identify molecules that induce sleep, ... This molecule, which they named nemuri, is an anti-microbial peptide. Its expression is switched on by infection or sleep ... 2014: Mapped neural circuits that link the clock to behavior 2014: Discovered a function of sleep in early life 2018: ... They showed that in flies, NF1 functions through the MAP kinase pathway, which is the same pathway implicated in ...

... was the first gene to be mapped to this particular region. It spans approximately 250kb and includes 10 exons within its ... Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described. This gene is ... Sinnett D, Wagstaff J, Glatt K, Woolf E, Kirkness EJ, Lalande M (June 1993). "High-resolution mapping of the gamma-aminobutyric ... Russek SJ, Farb DH (October 1994). "Mapping of the beta 2 subunit gene (GABRB2) to microdissected human chromosome 5q34-q35 ...

Cholecystokinin tetrapeptide (CCK-4, tetragastrin, Trp-Met-Asp-Phe-NH2) is a peptide fragment derived from the larger peptide ... February 2009). "Functional neuroanatomy of CCK-4-induced panic attacks in healthy volunteers". Human Brain Mapping. 30 (2): ... Since it is a peptide, CCK-4 must be administered by injection, and is rapidly broken down once inside the body so has only a ... García-López MT, González-Muñiz R, Martín-Martínez M, Herranz R (2007). "Strategies for design of non peptide CCK1R agonist/ ...

Herwald H, Jahnen-Dechent W, Alla SA, Hock J, Bouma BN, Müller-Esterl W (July 1993). "Mapping of the high molecular weight ... and trypsin with amino acid and peptide thioesters: development of new sensitive substrates". Biochemistry. 20 (25): 7196-206. ... Herwald H, Jahnen-Dechent W, Alla SA, Hock J, Bouma BN, Müller-Esterl W (1993). "Mapping of the high molecular weight kininogen ... Renné T, Dedio J, Meijers JC, Chung D, Müller-Esterl W (1999). "Mapping of the discontinuous H-kininogen binding site of plasma ...

... identity with Formyl peptide receptor 2, which likewise is also a receptor for N-formyl peptides but also a receptor for ... GPR32 mapped to chromosomal 19, region q13.3. There are no mouse or other orthologs of GPR32. The GPR32 protein is a G protein ... identity with Formyl peptide receptor 1, which is a receptor for N-Formylmethionine-leucyl-phenylalanine and related N-formyl ...

Peptides. 26 (8): 1481-1485. doi:10.1016/j.peptides.2005.03.020. PMID 15876475. S2CID 45499654. Magenis RE, Smith L, Nadeau JH ... This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat ... Pyrrolidine bis-cyclic guanidines, non-peptide small molecule MC3 agonists, good selectivity over MC4 but not over MC1 or MC5. ... Johnson KR, Mountjoy KG, Cone RD (August 1994). "Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in ...

Ramaekers A, Magnenat E, Marin EC, Gendre N, Jefferis GSXE, Luo L, Stocker RF (2005) Glomerular maps without cellular ... Ottiger M, Soller M, Stocker RF, Kubli E (2000) Binding sites of Drosophila melanogaster sex-peptide pheromones. J. Neurobiol. ... Jefferis GSXE, Marin EC, Stocker RF, Luo LL (2001) Target neuron prespecification in the olfactory map of Drosophila. Nature ... These studies were instrumental to map the wiring of olfactory sensory neurons expressing different olfactory receptor genes to ...

... thanks to the crystal structure determinations of amino acids and peptides and Pauling's prediction of planar peptide bonds; ... Terwilliger TC (March 2010). "Rapid model building of alpha-helices in electron-density maps". Acta Crystallographica Section D ... Common to many of them is that the hydrophobic face of the antimicrobial peptide forms pores in the plasma membrane after ... This pattern is especially common in antimicrobial peptides, and many models have been devised to describe how this relates to ...

... see Logical partition Map-dot-fingerprint dystrophy, a genetic disease affecting the cornea Mean Diastolic Filling of the heart ... Myocardial depressant factor, a low-molecular-weight peptide released from the pancreas into the blood in mammals during ...

In May 2014, a draft map of the human proteome was published in Nature. This map was generated using high-resolution Fourier- ... Peptide mass fingerprinting identifies a protein by cleaving it into short peptides and then deduces the protein's identity by ... Currently, several projects aim to map the human proteome, including the Human Proteome Map, ProteomicsDB, isoform.io, and The ... The Human Proteome Map currently (October 2020) claims 17,294 proteins and ProteomicsDB 15,479, using different criteria. On ...

... (EC 3.4.11.18, methionine aminopeptidase, peptidase M, L-methionine aminopeptidase, MAP) is an enzyme ... from peptides and arylamides This membrane-bound enzymatic activity is present in both prokaryotes and eukaryotes. Proteins ...