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*  Epoxide hydrolase
... has been proposed to be involved in limiting inflammatory reactions caused by this or other aminopeptidase-susceptible peptides ... Microsomal epoxide hydrolase (epoxide hydrolase 1, EH1, or mEH), soluble epoxide hydrolase (sEH, epoxide hydrolase 2, EH2, or ... Other enzymes with epoxide hydrolase activity include leukotriene A4 hydrolase, Cholesterol-5,6-oxide hydrolase, MEST (gene) ( ... The structure of hydrolase B contains a cap domain, which is hypothesized to regulate the active site of the hydrolase. ...
*  Signal peptidase II
Dev, I.K.; Ray, P.H. (1990). "Signal peptidases and signal peptide hydrolases". J. Bioenerg. Biomembr. 22: 271-290. doi:10.1007 ... This enzyme catalyses the following chemical reaction Release of signal peptides from bacterial membrane prolipoproteins ...
*  Acylaminoacyl-peptidase
Kobayashi, K.; Smith, J.A. (1987). "Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction". J. Biol. Chem ... Acylaminoacyl-peptidase (EC 3.4.19.1, acylamino-acid-releasing enzyme, N-acylpeptide hydrolase, N-formylmethionine (fMet) ... aminopeptidase, alpha-N-acylpeptide hydrolase) is an enzyme. This enzyme catalyses the following chemical reaction Cleavage of ...
*  APEH (gene)
"Entrez Gene: APEH N-acylaminoacyl-peptide hydrolase". Human APEH genome location and APEH gene details page in the UCSC Genome ... 2000). "Identification of oxidized protein hydrolase of human erythrocytes as acylpeptide hydrolase". Biochim. Biophys. Acta. ... The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It ... 1992). "Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme". J. Biol. Chem. 267 (6): 3811-8. ...
*  MEP1A
Meprin A subunit alpha also known as endopeptidase-2 or PABA peptide hydrolase is the alpha subunit of the meprin A enzyme that ... "Entrez Gene: MEP1A meprin A, alpha (PABA peptide hydrolase)". Banerjee S, Oneda B, Yap LM, Jewell DP, Matters GL, Fitzpatrick ... 1994). "Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 ... 1999). "Composition of the peptide fraction in human blood plasma: database of circulating human peptides". J. Chromatogr. B. ...
*  MEP1B
1994). "Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 ... Substrates include bioactive peptides and extracellular matrix proteins. See MIM 600388 for further information on meprins.[ ... 1997). "Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and ... 2001). "Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity". J. Biol. Chem. ...
*  PSMB4
... a homologue of the yeast PRE4-subunit essential for peptidylglutamyl-peptide hydrolase activity". FEBS Lett. 346 (2-3): 151-5. ... An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene ... Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin- ...
*  Signal peptidase I
... signal peptide hydrolase, signal peptide peptidase, signalase, bacterial leader peptidase 1) is an enzyme. This enzyme ... leader peptide hydrolase, leader proteinase, signal peptidase, pilin leader peptidase, SPC, prokaryotic signal peptidase, ...
*  Meprin A
PABA-peptide hydrolase, PPH) is an enzyme that cleaves protein and peptide substrates preferentially on carboxyl side of ... Meprin A (EC 3.4.24.18, endopeptidase-2, meprin-a, meprin, N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase, ...
*  Pyroglutamyl-peptidase I
L-pyroglutamyl peptide hydrolase, pyrrolidone-carboxyl peptidase, pyrrolidone-carboxylate peptidase, pyrrolidonyl peptidase, L- ... from pGlu-peptides and pGlu-proteins". Proteins. 20 (1): 34-51. doi:10.1002/prot.340200106. PMID 7824521. Patti, J.M.; ...
*  Bleomycin hydrolase
... and peptide ligase". Cell. 93 (1): 103-9. doi:10.1016/S0092-8674(00)81150-2. PMID 9546396. Koldamova RP, Lefterov IM, DiSabella ... Bleomycin hydrolase is an enzyme that in humans is encoded by the BLMH gene. Bleomycin hydrolase (BMH) is a cytoplasmic ... Koldamova, R P; Lefterov I M; DiSabella M T; Almonte C; Watkins S C; Lazo J S (June 1999). "Human bleomycin hydrolase binds ... 1998). "Bleomycin hydrolase is associated with risk of sporadic Alzheimer's disease". Nat. Genet. 18 (3): 211-2. doi:10.1038/ ...
*  Peptidyl-dipeptidase B
J. Peptide Protein Res. 32: 35-40. PMID 3146555. Soler, D.F.; Harris, R.B. (1989). "Atrial dipeptidyl carboxyhydrolase is a ... Harris, R.B.; Wilson, I.B. (1985). "Conversion of atriopeptin II to atriopeptin I by atrial dipeptidyl carboxy hydrolase". ... atrial peptide convertase) is an enzyme. It catalyses the following chemical reaction Release of a C-terminal dipeptide or ... Peptides (Fayetteville). 6: 393-396. doi:10.1016/0196-9781(85)90102-0. PMID 2999723. Soler, D.F.; Harris, R.B. (1988). " ...
*  RAD23B
Park H, Suzuki T, Lennarz WJ (Sep 2001). "Identification of proteins that interact with mammalian peptide:N-glycanase and ... implicate this hydrolase in the proteasome-dependent pathway for protein degradation". Proceedings of the National Academy of ...
*  Enzyme Commission number
EC 3.4 are hydrolases that act on peptide bonds EC 3.4.11 are those hydrolases that cleave off the amino-terminal amino acid ... EC 3 enzymes are hydrolases (enzymes that use water to break up some other molecule) ...
*  Aliphatic nitrilase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ...
*  Thiocyanate hydrolase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... Katayama Y, Narahara Y, Inoue Y, Amano F, Kanagawa T, Kuraishi H (1992). "A thiocyanate hydrolase of Thiobacillus thioparus. A ... In enzymology, a thiocyanate hydrolase (EC 3.5.5.8) is an enzyme that catalyzes the chemical reaction thiocyanate + 2 H2O ⇌ {\ ... "Cloning of genes coding for the three subunits of thiocyanate hydrolase of Thiobacillus thioparus THI 115 and their ...
*  Glutaryl-7-aminocephalosporanic-acid acylase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ...
*  Aminoimidazolase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... This enzyme is also called 4-aminoimidazole hydrolase. This enzyme participates in purine metabolism. It employs one cofactor, ...
*  Pantetheine hydrolase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... In enzymology, a pantetheine hydrolase (EC 3.5.1.92) is an enzyme that catalyzes the chemical reaction (R)-pantetheine + H2O ...
*  Creatinine deaminase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... Other names in common use include creatinine hydrolase, and creatinine desiminase. This enzyme participates in arginine and ...
*  N-carbamoyl-D-amino acid hydrolase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... In enzymology, a N-carbamoyl-D-amino acid hydrolase (EC 3.5.1.77) is an enzyme that catalyzes the chemical reaction N-carbamoyl ...
*  Gamma-glutamyl-gamma-aminobutyrate hydrolase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... Other names in common use include gamma-glutamyl-GABA hydrolase, PuuD, and YcjL. This enzyme participates in urea cycle and ... In enzymology, a gamma-glutamyl-gamma-aminobutyrate hydrolase (EC 3.5.1.94) is an enzyme that catalyzes the chemical reaction 4 ...
*  Allophanate hydrolase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... Kanamori T, Kanou N, Kusakabe S, Atomi H, Imanaka T (2005). "Allophanate hydrolase of Oleomonas sagaranensis involved in an ATP ... In enzymology, an allophanate hydrolase (EC 3.5.1.54) is an enzyme that catalyzes the chemical reaction allophanate + 3 H2O + ... Sumrada RA, Cooper TG (1982). "Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast ...
*  Blasticidin-S deaminase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ...
*  Amidase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ... which catalyses the hydrolysis of the C-terminal amide bond of peptides. Fatty acid amide hydrolases, which hydrolyse fatty ... Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF (December 2006). "A second fatty acid amide hydrolase with variable ... Valiña AL, Mazumder-Shivakumar D, Bruice TC (December 2004). "Probing the Ser-Ser-Lys catalytic triad mechanism of peptide ...
*  Metabolism
Amino acids are made into proteins by being joined together in a chain of peptide bonds. Each different protein has a unique ... These digestive enzymes include proteases that digest proteins into amino acids, as well as glycoside hydrolases that digest ... Proteins are made of amino acids arranged in a linear chain joined together by peptide bonds. Many proteins are enzymes that ...
*  4-acetamidobutyrate deacetylase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically ...