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*  Prokaryotic elongation factors
Peptide Elongation Factor G at the US National Library of Medicine Medical Subject Headings (MeSH) Peptide Elongation Factor Tu ... Elongation factor Eukaryotic elongation factor PDB Molecule of the Month Elongation factors - September 2006 ... In prokaryotes, four elongation factors are required for translation: EF-Tu, EF-Ts, EF-G and EF-P. EF-Tu mediates the entry of ... EF-Ts serves as the guanine nucleotide exchange factor for EF-Tu, catalyzing the release of GDP from EF-Tu. EF-G catalyzes the ...
*  List of MeSH codes (D08)
... peptide elongation factor g MeSH D08.811.277.040.330.300.100.700 --- peptide elongation factor tu MeSH D08.811.277.040.330.300. ... peptide elongation factor 1 MeSH D08.811.277.040.330.300.100.850 --- peptide elongation factor 2 MeSH D08.811.277.040.330.300. ... factor ixa MeSH D08.811.277.656.300.760.315 --- factor xa MeSH D08.811.277.656.300.760.320 --- factor xia MeSH D08.811.277.656. ... gtp phosphohydrolase-linked elongation factors MeSH D08.811.277.040.330.300.100.200 --- ...
*  EF-Tu
Peptide Elongation Factor Tu at the US National Library of Medicine Medical Subject Headings (MeSH). ... EF-Tu (elongation factor thermo unstable) is a prokaryotic elongation factor responsible for catalyzing the binding of an ... EF-Ts (elongation factor thermo stable) EF-G eEF-1 EEF-2 EFR (EF-Tu receptor) PDB Molecule of the Month EF-Tu Weijland, A.; ... In the cytoplasm, the deactivated EF-Tu • GDP is acted on by the prokaryotic elongation factor EF-Ts, which causes EF-Tu to ...
*  List of MeSH codes (D12.776)
... peptide elongation factor g MeSH D12.776.835.700.350.700 - peptide elongation factor tu MeSH D12.776.835.700.350.800 - peptide ... elongation factor 1 MeSH D12.776.835.700.350.850 - peptide elongation factor 2 MeSH D12.776.835.725.868.124 - eukaryotic ... vascular endothelial growth factor a MeSH D12.776.467.100.800.300 - vascular endothelial growth factor b MeSH D12.776.467.100. ... fibroblast growth factor 4 MeSH D12.776.624.664.700.112 - fibroblast growth factor 6 MeSH D12.776.624.664.700.114 - fms-like ...
*  List of MeSH codes (D12.776.157)
... peptide elongation factor g MeSH D12.776.157.325.150.700 -- peptide elongation factor tu MeSH D12.776.157.325.150.800 -- ... peptide elongation factor 1 MeSH D12.776.157.325.150.850 -- peptide elongation factor 2 MeSH D12.776.157.325.332.100 -- gtp- ... adp-ribosylation factors MeSH D12.776.157.325.515.100.100 -- adp-ribosylation factor 1 MeSH D12.776.157.325.515.400 -- rab gtp- ... tnf receptor-associated factor 1 MeSH D12.776.157.057.500.750 -- tnf receptor-associated factor 2 MeSH D12.776.157.057.500.875 ...
*  GTP-binding elongation factor family, EF-Tu/EF-1A subfamily
The GTP-binding protein synthesis factor family also includes the eukaryotic peptide chain release factor GTP-binding subunits ... In molecular biology, the GTP-binding elongation factor family, EF-Tu/EF-1A subfamily is a family of elongation factors, which ... "A conserved amino acid sequence around Arg-68 of Artemia elongation factor 1 alpha is involved in the binding of guanine ... and the prokaryotic selenocysteine-specific elongation factor selB. Domain 2 adopts a beta-barrel structure, and is involved in ...
*  Aminoacyltransferase
The aminoacyl-tRNA molecule has close relationships with elongation factors like EF-Tu. Peptidyl transferases are also a type ... of aminoacyltransferase that catalyze the formation of peptide bonds, as well as the hydrolytic step that leads to the release ...
*  Sulcia muelleri
... elongation factor Tu, the RNA polymerase beta-subunit, and the ribosomal proteins L2, S5, and S11. Where S. muelleri is found ... The tree was constructed by comparing the peptide sequences of ten different types of proteins. The proteins used were the DNA ... polymerase III beta-subunit, initiation factor IF-2, leucyl-tRNA synthetase, the phenylalanine-tRNA ligase beta-subunit, VARS, ...
*  Protein-synthesizing GTPase
... s (EC 3.6.5.3, elongation factor (EF), initiation factor (IF), peptide-release or termination factor ... They usually include translation initiation factors such as IF-2 and translation elongation factors such as EF-Tu. Kurzchalia, ... Rodnina, M.V.; Savelsberg, A.; Katunin, V.I.; Wintermeyer, W. (1997). "Hydrolysis of GTP by elongation factor G drives tRNA ... Freistroffer, D.V.; Pavlov, M.Y.; MacDougall, J.; Buckingham, R.H.; Ehrenberg, M. (1997). "Release factor RF3 in E. coli ...
*  Prokaryotic translation
This binding is facilitated by elongation factor-Tu (EF-Tu), a small GTPase. For fast and accurate recognition of the ... And the E site which is the exit site of the now uncharged tRNA after it gives its amino acid to the growing peptide chain. The ... Prokaryotic initiation factors Prokaryotic elongation factors Prokaryotic factors Farabaugh, Philip J. (1978-08-24). "Sequence ... Once the nascent protein is released in termination, Ribosome Recycling Factor and Elongation Factor G (EF-G) function to ...
*  Thiostrepton
"Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu". J. Am. Chem. Soc. 131 (16): 5946-55. doi: ... The precursor of thiostrepton contains 58 amino acids in the peptide chain, which includes 41-aa leading peptide (LP) and 17-aa ... Bycroft, Barrie W.; Gowland, Maxim S. (1978). "The structures of the highly modified peptide antibiotics micrococcin P1 and P2 ... Thiostrepton is a natural product of the ribosomally synthesized and post-translationally modified peptide (RiPP) class. ...
*  Index of biochemistry articles
... peptide - peptide bond - peptide elongation factor - peptide elongation factor tu - peptide fragment - peptide initiation ... transforming growth factor - transforming growth factor alpha - transforming growth factor beta - transforming growth factor ... factor - peptide receptor - peptide termination factor - peripheral membrane protein - pesticide - pH - phage display - ... sigma factor - signal peptide - signal recognition particle - signal sequence - signal transduction - sincalide - skeleton - ...
*  Elongation factor
Eukaryotic elongation factors GTP-binding elongation factor family, EF-Tu/EF-1A subfamily Prokaryotic elongation factors ... In the ribosome, they facilitate translational elongation, from the formation of the first peptide bond to the formation of the ... Elongation factors are a set of proteins that are used in protein synthesis in the process of cell cycle and elongation in some ... Elongation factors play a role in orchestrating the events of this process, and in ensuring the 99.99% accuracy of translation ...
*  Transfer RNA
During translation elongation, tRNA first binds to the ribosome as part of a complex with elongation factor Tu (EF-Tu) or its ... Once the peptide bond is formed, the tRNA in the P/P site is deacylated, or has a free 3' end, and the tRNA in the A/A site ... These are the T site (named elongation factor Tu) and I site (initiation). By convention, the tRNA binding sites are denoted ... and elongation factors EF-G and EF-Tu". Q Rev Biophys. 42 (3): 159-200. doi:10.1017/S0033583509990060. PMC 2832932 . PMID ...
*  Leader peptidase A
"GTP-binding membrane protein of Escherichia coli with sequence homology to initiation factor 2 and elongation factors Tu and G ... Additionally, LepA has an effect on peptide bond formation. Through various studies in which functional derivatives of ... Prokaryotic elongation factors Eukaryotic elongation factors Youngman EM, Green R (February 2007). "Ribosomal translocation: ... There are three primary elongation factors (EF-G, EF-Tu, EF-Ts) that are known to be the main contributors to facilitate ...
*  Eukaryotic translation elongation factor 1 alpha 1
Rao TR, Slobin LI (Mar 1986). "Structure of the amino-terminal end of mammalian elongation factor Tu". Nucleic Acids Research. ... "Protein kinase C delta-specific phosphorylation of the elongation factor eEF-alpha and an eEF-1 alpha peptide at threonine 431 ... an elongation factor protein, a GTPase, and an actin bundling protein. As an elongation factor, it is known to mediate the ... "An elongation factor-like protein (EF-Tu) elicits a humoral response in infiltrating ductal breast carcinomas: an ...
*  TSFM
1996). "Interaction of mitochondrial elongation factors Tu.Ts with aminoacyl-tRNA". Nucleic Acids Symp. Ser. (33): 163-6. PMID ... Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in ... Elongation factor Ts, mitochondrial is a protein that in humans is encoded by the TSFM gene. GRCh38: Ensembl release 89: ... Vernon JL, Burr PC, Wiley JE, Farwell MA (2000). "Assignment of the mitochondrial translation elongation factor Ts gene (TSFM) ...
*  TUFM
"The human mitochondrial elongation factor tu (EF-Tu) gene: cDNA sequence, genomic localization, genomic structure, and ... "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. ... Elongation factor Tu, mitochondrial is a protein that in humans is encoded by the TUFM gene. GRCh38: Ensembl release 89: ... "Entrez Gene: TUFM Tu translation elongation factor, mitochondrial". Wells J, Henkler F, Leversha M, Koshy R (1995). "A ...
*  Ribosomal L28e protein family
Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF- ... While the crucial activities of decoding and peptide transfer are RNA based, proteins play an active role in functions that may ... is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ... Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and ...
*  EEF-1
... is a eukaryotic elongation factor. Its α and βγ subunits act as counterparts to EF-Tu and EF-Ts, respectively Genes ... Biol., 9: 39, doi:10.1186/1471-2148-9-39, PMC 2652445 , PMID 19216746 Peptide Elongation Factor 1 at the US National Library of ... elongation factor-like). Although its function has not been studied in depth, it appears to be similar to EF-1α. Only two ... "Gain and loss of elongation factor genes in green algae", BMC Evol. ...
*  Transfer-messenger RNA
The tmRNA forms a ribonucleoprotein complex (tmRNP) together with Small Protein B (SmpB), Elongation Factor Tu (EF-Tu), and ... for the tag peptide, marked by the resume codon and the stop codon. The encoded tag peptide (ANDENYALAA in E. coli) varies ... Tu GF, Reid GE, Zhang JG, Moritz RL, Simpson RJ (April 1995). "C-terminal extension of truncated recombinant proteins in ... Depending on the organism, the tag peptide may be recognized by a variety of proteases or protease adapters. ssrA is both a ...
*  EF-G
Peptide Elongation Factor G at the US National Library of Medicine Medical Subject Headings (MeSH). ... Just like the EF-Tu+tRNA+GTP complex, EF-G binds to the ribosome in its GTP-bound state. When it binds to the ribosome A-site, ... EF-G or elongation factor G (historically known as translocase) is a prokaryotic elongation factor and a GTPase responsible for ... G C Atkinson; S L Baldauf (2011). "Evolution of elongation factor G and the origins of mitochondrial and chloroplast forms". ...
*  Translation (biology)
Then, a peptide bond forms between the amino acid of the tRNA in the A site and the amino acid of the charged tRNA in the P ... Elongation: The tRNA transfers an amino acid to the tRNA corresponding to the next codon. The ribosome then moves (translocates ... This aminoacyl-tRNA is carried to the ribosome by EF-Tu, where mRNA codons are matched through complementary base pairing to ... Instead, the stop codon induces the binding of a release factor protein that prompts the disassembly of the entire ribosome/ ...
*  2-oxoglutarate (2OG)-dependent dioxygenases
"Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation". Proc. Natl. Acad. Sci. U.S.A. ... by substrate analog peptides". Bioorg. Med. Chem. Lett. 21 (14): 4325-4328. doi:10.1016/j.bmcl.2011.05.050. PMID 21665470. CS1 ... "Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain ... and factor inhibiting HIF (FIH)". J. Inorg. Biochem. 113: 25-30. doi:10.1016/j.jinorgbio.2012.03.002. PMID 22687491. CS1 maint ...
*  Nediljko Budisa
"Entropic Contribution of Elongation Factor P to Proline Positioning at the Catalytic Center of the Ribosome". J. Am. Chem. Soc ... He was appointed as full professor at the TU Berlin in 2010. Ned Budisa is also a member of the Excellence Cluster 'Unifying ... "Expanded genetic code for the engineering of ribosomally synthetized and post-translationally modified peptide natural products ... 2004: BioFuture Award 2017: Publication Award Fluorine Chemistry Homepage of the TU Berlin UniCat profile Talk about the future ...
*  Pattern recognition receptor
Since that time two other plants PRRs, Arabidopsis FLS2 (flagellin) and EFR (elongation factor Tu receptor)have been isolated. ... bacterial peptides (flagellin, microtubule elongation factors), peptidoglycans and lipoteichoic acids (from Gram-positive ... Mutations in NOD2 in cooperation with environmental factors lead to development of chronic inflammation in the intestine. ... and single stranded RNA which recruit factors via twin N-terminal CARD domains to activate antiviral gene programs, which may ...