Cressey, Daniel (2013). "The resistance against resistance". Nature. doi:10.1038/nature.2013.13086. S2CID 179507057. Retrieved ... in 1981 and was awarded a PhD by the University of Birmingham in 1985 for work on penicillin binding proteins with Richard Wise ... Her research concentrates on the origin of antibiotic resistance in bacteria but also includes a broad interest in all aspects ... The genes for aspects of antibiotic resistance are often found on mobile genetic elements (plasmids) and her research is ...
This particular resistance is believed to be due to a surfactant-like liquid front that actually forms a particular pattern on ... penicillin, kanamycin, chloramphenicol, ampicillin, tetracycline, spectinomycin, streptomycin, and mitomycin C). Colonies that ... including β-galactosidase-like activity causing colonies to turn blue on X-gal plates and multiple drug resistance (MDR) ( ... are grown on surfaces in Petri dishes exhibit several-fold higher drug resistance in comparison to growth in liquid media. ...
... no documented resistance of Group A Streptococcus to penicillin has ever been reported, and penicillin or amoxicillin is ... and strep throat which may be used in those with a severe allergy to penicillin. It is taken by mouth. Common side effects ... preferred except in penicillin allergic patients), community-acquired pneumonia, and acute exacerbations of bronchitis. ...
He then collaborated with Mexican scientists Emma Galindo and Jorge Olarte to investigate new forms of penicillin resistance in ... Falkow also was one of the first scientists to investigate antimicrobial resistance, and presented his research extensively to ... Here he described how meningitis and gonorrhea organisms acquire plasmids to become resistant to penicillin and other ... Falkow organized the first international symposium of invited speakers on antimicrobial resistance. Falkow and his student ...
... penicillin resistance MeSH G04.185.515.286.347.500.600.050 - ampicillin resistance MeSH G04.185.515.286.347.500.600.525 - ... drug resistance, viral MeSH G04.185.515.286.420.500 - drug resistance, multiple, viral MeSH G04.185.515.329 - drug resistance, ... vancomycin resistance MeSH G04.185.515.286.383 - drug resistance, fungal MeSH G04.185.515.286.383.500 - drug resistance, ... methicillin resistance MeSH G04.185.515.286.347.750 - chloramphenicol resistance MeSH G04.185.515.286.347.812 - drug resistance ...
The potential role of ADEPs in combating antibiotic drug resistance is postulated due to their novel mode of action that other ... penicillin-resistant Streptococcus pneumoniae (PRSP), Mycobacterium tuberculosis, and others. Despite the potential use of ADEP ... Gominet, M.; Seghezzi, N.; Mazodier, P. (2011). "Acyl depsipeptide (ADEP) resistance in Streptomyces". Microbiology. 157 (8): ... possible resistance has been examined in certain species. Chemical structures of natural ADEPs Enopeptin A Enopeptin B A54556A ...
So far no observed L. fermentum strains have been observed to have transferable resistance or acquired resistance genes. ... Out of ten common antibiotic genes that were tested (gatamicin, cefazolin, penicillin, trimethoprim/sulfmethoxazole, ampicillin ... Different strains of L. fermentum demonstrated uniform resistance patterns demonstrating resistance to glycopeptide and to ... it must not contain any transferable antibiotic resistance genes. If a resistance gene is transferable, it could lessen the ...
... showed that impaired penetration had a role in biofilm resistance to penicillin, norfloxacin, chloramphenicol, and Gm, and that ... Matin conducted research on the bacterial antibiotic resistance along with the threat of multidrug resistance (MDR) pumps in ... That biofilm resistance differ for different antibiotics and different bacteria is now widely accepted. Matin has also studied ... Lynch, S. V.; Brodie, E. L.; Matin, A. (December 16, 2004). "Role and Regulation of σs in General Resistance Conferred by Low- ...
... or How to Promote Resistance 1977 Jean-Marie Ghuysen, The Concept of the Penicillin Target from 1965 until Today 1979 D. ... Understanding the Basis of Antibiotic Resistance as a Platform for Early Drug Discovery 2015 Robin Weiss, What's the host and ...
Infection or carrier state of Streptococcus pneumoniae with reduced susceptibility to penicillin Infection or carrier state of ... C HPV-infection causing cancer or pre-cancerous lesions Infection or carrier state of microbes with special resistance patterns ...
He and his older siblings were involved in the popular resistance. Razis studied medicine in the University of Athens, ... an indelible mark on the young medical student who still remembers that on the black market a single injection of Penicillin ...
Resistance to fluoroquinolones is common in staphylococcus and pseudomonas. Resistance occurs in multiple ways. One mechanism ... Usage of levofloxacin eye drops, along with an antibiotic injection of cefuroxime or penicillin during cataract surgery, has ... "Antibiotic Resistance Threats in the United States, 2013" (PDF). Archived (PDF) from the original on 17 November 2014. Gower EW ... ECDC (2014). "Antimicrobial resistance surveillance in Europe 2014". Archived (PDF) from the original on 14 April 2016. CDC. " ...
This provides acid resistance and is thus important for colonization of the bacterium in the gastric epithelial cells. Arginase ... In patients with any previous macrolide exposure or who are allergic to penicillin, a quadruple therapy that consisting of a ... However, antibiotic resistance is appearing in H. pylori; many metronidazole- and clarithromycin-resistant strains are found in ... Fischbach L, Evans EL (August 2007). "Meta-analysis: the effect of antibiotic resistance status on the efficacy of triple and ...
... beta-lactam resistance MeSH G12.392.269.347.500.175 - cephalosporin resistance MeSH G12.392.269.347.500.600 - penicillin ... drug resistance, fungal MeSH G12.392.269.383.500 - drug resistance, multiple, fungal MeSH G12.392.269.420 - drug resistance, ... drug resistance, multiple, fungal MeSH G12.392.300.750 - drug resistance, multiple, viral MeSH G12.392.395 - drug resistance, ... kanamycin resistance MeSH G12.392.269.347.937 - tetracycline resistance MeSH G12.392.269.347.968 - trimethoprim resistance MeSH ...
She also published a book, Penicillin: Meeting the Challenge, in 1985, in which she described penicillin's journey from the ... Antimicrobial Agents and Chemotherapy (Editor), Journal (1972 - 1980) Primary Drug Resistance - Continuing Study of Drug ... Her work took penicillin from a laboratory experiment to a mass-produced drug during World War II. Hobby was born in the ... They discovered that penicillin was a powerful germ-killer that reduced the severity of infectious diseases and made procedures ...
The main problem with pathogenic drug treatments in the modern world is drug resistance. Many patients don't take the full ... Antibiotics are chemicals made by microbes that can be used against other pathogens, such as penicillin and erythromycin. Semi- ... Neu HC (August 1992). "The crisis in antibiotic resistance". Science. 257 (5073): 1064-1073. Bibcode:1992Sci...257.1064N. doi: ...
Because of their activity on b-lactamase, this class of antibiotics can evade antibiotic resistance in bacteria, which is a ... risk associated with other antibiotics such as penicillins. In S Clavuligerus infection, a Streptomyces antibiotic regulatory ...
Likewise, their antibiotic resistance may also vary, requiring a different choice of stand-by antibiotic. Surgical and dental ... erythromycin in patients allergic to penicillin). Tick bites - Babesiosis is a rare tickborne infection. Patients should check ...
Besides intrinsic resistance, P. aeruginosa easily develops acquired resistance either by mutation in chromosomally encoded ... are naturally resistant to penicillin and the majority of related beta-lactam antibiotics, but a number are sensitive to ... Their resistance to most antibiotics is attributed to efflux pumps, which pump out some antibiotics before they are able to act ... Theories include: the bacteria might induce systemic resistance in the host plant, so it can better resist attack by a true ...
Because of the interaction between penicillin and transpeptidase, this enzyme is also known as penicillin-binding protein (PBP ... implication in drug resistance". Journal of Molecular Biology. 299 (2): 477-85. doi:10.1006/jmbi.2000.3740. PMID 10860753. ... Yocum RR, Waxman DJ, Rasmussen JR, Strominger JL (1979). "Mechanism of penicillin action: penicillin and substrate bind ... presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent". Microbiology ...
They are thinner, cover less surface area, and are less hydrophobic, but they also have an increased level of resistance to ... Various strains are resistant to one or more of these antibiotics: penicillins, cephalosporins, macrolides, quinolones, ... 2006). "Antimicrobial Resistance and Production of Biofilms in Clinical Isolates of Coagulase-Negative Staphylococcus Strains ... 2011). "Antibiotic resistance and molecular characterization of clinical isolates of methicillin-resistant coagulase-negative ...
The antibiotic families that C. acnes are most likely to acquire resistance to are the macrolides (e.g., erythromycin and ... penicillins, and sulfonamides. The emergence of antibiotic-resistant C. acnes bacteria represents a growing problem worldwide. ... However, with the rise of antibiotic resistance, antibiotics are now often combined with broad-spectrum antibacterial agents ...
She received the resistance war gold medal. Li Binzhu died on 12 July 2007 in Vienna. The mourning statement of the Chinese ... while caring for her child born in the war and assisting her husband in producing penicillin, which he had already started in ... After defeating the War of Resistance, Richard Frey and Li Binzhu, who was pregnant at the time, marched with the army into the ... In 2005, on the occasion of the commemoration of the 60th anniversary of the victory in the War of Resistance, the Chinese ...
In general, the species of Anaerococcus presents susceptibility to penicillins but are resistant to tetracycline, erythromycin ... Studies has shown Anaerococcus prevotii presents resistance to Ceftazidime, Clindamycin, Levofloxacin. Unlike the other species ... The first analysis made on Anaerococcus provencensis showed it is susceptible to penicillin G, imipenem, amoxillin, ...
Some of the more-studied resistance mechanisms include: utilization of beta-lactamases, which are able to cleave penicillins, ... In order to gain resistance to fluoroquinolones, mutations in the gyrA (gyrase gene) and parC(topoisomerase IV gene) are often ... The reason P. stutzeri strains are less of a concern for major antibiotic resistance as compared to other Pseudomonas strains, ... In fact, P. stutzeri has so many resistance mechanisms that antibiotic-resistant P. stutzeri strains have been discovered and ...
Her thesis topic was The effect of solute on the liquid film resistance in gas absorption. On 1 May 1939, she married William ... Her development of deep-tank fermentation of penicillium mold enabled large-scale production of penicillin. She worked on the ... was an American chemical engineer who designed the first commercial penicillin production plant. She was the first female ... she oversaw the design of production plants for the strategically important materials of penicillin and synthetic rubber. ...
This acquired resistance can be either plasmid-mediated or chromosomal, i.e., through mutation, and results in cross-resistance ... Erythromycin was widely used as a substitute to penicillin in cases where patients were allergic to penicillin or had ... Roland Leclercq (15 February 2002). "Mechanisms of Resistance to Macrolides and Lincosamides: Nature of the Resistance Elements ... Unlike penicillin, macrolides have been shown to be effective against Legionella pneumophila, mycoplasma, mycobacteria, some ...
"Antibiotic resistance". www.who.int. Retrieved 2021-05-04. Yoshikawa TT (July 2002). "Antimicrobial resistance and aging: ... Bacteriophage endolysins have been successful in preventing neonatal infections of penicillin-resistant Streptococcus ... As of July 2020, the World Health Organization considers antibiotic resistance "one of the biggest threats to global health, ... Enzybiotics are being researched largely to address the issue of antibiotic resistance, which has allowed for the proliferation ...
Resistance Reservoirs: Bacteroides species accumulate a variety of antibiotic/antimicrobial resistance genes as they reside in ... These organisms are resistant to penicillin by virtue of production of beta-lactamase, and by other unknown factors. This group ... Bile salt resistance: Utilizes enzymes such as bile salt hydrolase to resist the degrading effects of bile salts. Detergent ... The high resistance to antibiotics of B.fragilis is mainly attributed to genetic plasticity. Species of the Bacteroidaceae have ...
Review on Antimicrobial Resistance. Retrieved 5 March 2020. "FACT SHEET: Obama Administration Releases National Action Plan to ... Administration of Recombinant Plasma Gelsolin Improves Survival in a Murine Model of Penicillin-Susceptible and Penicillin- ... "An international legal framework to address antimicrobial resistance". Bulletin of the World Health Organization. 93 (2): 66. ...