This makes PC12 cells useful as a model system for neuronal differentiation and neurosecretion. Treatment of PC12 cells with ... Wikipedia articles containing the term "PC12 cells" [1] Ras function was partially elucidated using PC12 cell line [2], from ... been studied using this cell line to understand their effects on PC12 cells These types of studies show that use of PC12 cell ... "The PC12 cell as model for neurosecretion: PC12 cells as model for neurosecretion". Acta Physiologica. 192 (2): 273-285. doi: ...
TDCPP was found to affect several neurodevelopmental processes in a neuronal cell line. PC12 cells showed decreased cell ... Studies in PC12 cells". Toxicology and Applied Pharmacology. 256 (3): 281-9. doi:10.1016/j.taap.2011.01.005. PMC 3089808. PMID ... When the TDCPP exposure began very early during embryogenesis, by the 2 cell stage, the developing embryos were more severely ... In a developing organism, these effects could change the way the brain cells communicate and function, resulting in permanent ...
Bai L, Swayne LA, Braun JE (January 2007). "The CSPalpha/G protein complex in PC12 cells". Biochem. Biophys. Res. Commun. 352 ( ... Cell. 123 (3): 383-96. doi:10.1016/j.cell.2005.09.028. PMID 16269331. S2CID 18173864. Swayne LA, Beck KE, Braun JE (September ... It is also found on secretory vesicles in endocrine, neuroendocrine and exocrine cells. This protein makes up ~1% of the ... 1999). "Mutational analysis of cysteine-string protein function in insulin exocytosis". J. Cell Sci. 112 (9): 1345-51. doi: ...
"Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells". The Journal of Biological Chemistry. 277 (7): 4601-4. doi: ... Journal of Cell Science. 116 (Pt 21): 4307-18. doi:10.1242/jcs.00719. PMID 12966166. Morenilla-Palao C, Planells-Cases R, ... Journal of Cell Science. 116 (Pt 21): 4307-18. doi:10.1242/jcs.00719. PMID 12966166. \* Dubois T, Howell S, Zemlickova E, ...
Chapman ER, Blasi J, An S, Brose N, Johnston PA, Südhof TC, Jahn R (Aug 1996). "Fatty acylation of synaptotagmin in PC12 cells ... systemic mast cell disease, and a human mast cell leukemia cell line". The Journal of Histochemistry and Cytochemistry. 49 (3 ... O'Regan S, Diebler MF, Meunier FM, Vyas S (Jan 1995). "A Ewing's sarcoma cell line showing some, but not all, of the traits of ... Kimura N, Shiraishi S, Mizunashi K, Ohtsu H, Kimura I (Mar 2001). "Synaptotagmin I expression in mast cells of normal human ...
Vaudry, D.; Stork, PJ; Lazarovici, P; Eiden, LE (31 May 2002). "Signaling Pathways for PC12 Cell Differentiation: Making the ... Lazarovici, Philip; Fink, Donald (August 1999). "Heterologous Upregulation of Nerve Growth Factor-TrkA Receptors in PC12 Cells ... in PC12 Cells". Journal of Molecular Neuroscience. 54 (3): 574-585. doi:10.1007/s12031-014-0388-2. PMID 25078264. S2CID 1620005 ... in PC12 Cells". Journal of Molecular Neuroscience. 54 (3): 574-585. doi:10.1007/s12031-014-0388-2. PMID 25078264. S2CID 1620005 ...
Nitric Oxide mediates laminin-induced neurite outgrowth in PC12 cells. Experimental Cell Research, 260(2): 268-276. Weston, C.A ... Besides anchoring cells to the ECM, laminins are also involved in the signalling of cells and other components of the ECM. Even ... In cell adhesion laminin-111 and other isoforms are important proteins that anchor cells to the extracellular matrix (ECM). The ... However, when an isoform of actin, that cannot exit a cell's nucleus, is active, cells continue to grow and divide even when ...
Meng J, Casey PJ (November 2002). "Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells". The Journal of ... regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells". ... Experimental Cell Research. 257 (1): 172-9. doi:10.1006/excr.2000.4877. PMID 10854065. Kao S, Jaiswal RK, Kolch W, Landreth GE ... Cell. 65 (6): 1033-42. doi:10.1016/0092-8674(91)90555-D. PMID 1904317. S2CID 45725280. "Entrez Gene: RAP1GAP RAP1 GTPase ...
Connection between cell surface signaling and nucleus in PC12 cells". The Journal of Biological Chemistry. 272 (49): 31130-7. ... Nucleolin at the cell surface is the receptor for the respiratory syncytial virus (RSV) fusion protein. Interference with the ... Said EA, Krust B, Nisole S, Svab J, Briand JP, Hovanessian AG (Oct 2002). "The anti-HIV cytokine midkine binds the cell surface ... Jordan P, Heid H, Kinzel V, Kübler D (Dec 1994). "Major cell surface-located protein substrates of an ecto-protein kinase are ...
Wu, Y., et al., Self-assembled IKVAV peptide nanofibers promote adherence of PC12 cells. Journal of Huazhong University of ... Early cell adhesion is very important for preventing cell degeneration; the longer cells are suspended in culture, the more ... The strength of cell attachment, cell migration rate, and extent of cytoskeletal organization formation is determined by the ... The IKVAV nanofibers promoted stronger cell adherence than the electrostatic attraction induced by poly-L-lysine, and cell ...
Jang JH, Aruoma OI, Jen LS, Chung HY, Surh YJ (February 2004). "Ergothioneine rescues PC12 cells from beta-amyloid-induced ... It is a metabolite of the antianginal drug molsidomine and acts by releasing NO from the endothelial cells nonenzymatically. It ... Wen TC, Rogido MR, Moore JE, Genetta T, Peng H, Sola A (October 2005). "Cardiotrophin-1 protects cortical neuronal cells ... also hyperpolarizes the cell membrane through influencing the sodium-potassium pump and thereby rendering it less responsive to ...
Shin JS, Kim KT, Lee MK (March 1998). "Inhibitory effects of bulbocapnine on dopamine biosynthesis in PC12 cells". Neuroscience ...
2002). "Glycine transporter isoforms show differential subcellular localization in PC12 cells". J. Neurochem. 82 (1): 58-65. ...
"Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells". Journal of Neurochemistry. 82 (6): 1406-15 ... cDNA was cloned into a synthetic plasmid and initially expressed in E. coli cells, followed by yeast cells with successful ... It is a serine protease (EC 3.4.21.68) found on endothelial cells lining the blood vessels. Human tPA is encoded by the PLAT ... Tissue plasminogen activator also plays a role in cell migration and tissue remodeling.[citation needed] Once in the body, tPA ...
"Receptor mechanisms mediating cyanide generation in PC12 cells and rat brain". Neurosci Res. 49 (1): 13-18. doi:10.1016/j. ... tissue or cell or are received by the organism, tissue or cell from outside (say, from the atmosphere or hydrosphere, as in the ... Cell Physiology. 304 (2): 207-214. doi:10.1152/ajpcell.00300.2012. PMID 23174561. Tuboly E, Szabó A, Erős G, Mohácsi A, Szabó G ... This effect was shown in lymphocyte cell cultures and in human liver biopsy samples. Nitrous oxide does not bind as a ligand to ...
Weber E, Jilling T, Kirk KL (March 1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". The ... Weber E, Jilling T, Kirk KL (March 1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". The ... "Expression and polarized targeting of a rab3 isoform in epithelial cells". The Journal of Cell Biology. 125 (3): 583-94. doi: ... localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells". Journal of Cell Science. 109 ...
Weber E, Jilling T, Kirk KL (March 1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". J. ... Cell. 96 (3): 363-74. doi:10.1016/S0092-8674(00)80549-8. PMID 10025402. S2CID 15162326. Jung YJ, Lee TH, Lee JY, Kim JH, Park ... Mol Cell Biol. 15 (3): 1137-43. doi:10.1128/MCB.15.3.1137. PMC 230335. PMID 7532276. "Entrez Gene: RAB3A RAB3A, member RAS ... Cell. Signal. 11 (10): 735-42. doi:10.1016/S0898-6568(99)00037-6. PMID 10574328. Clabecq A, Henry JP, Darchen F (2000). " ...
"Receptor mechanisms mediating cyanide generation in PC12 cells and rat brain". Neuroscience Research. 49 (1): 13-18. doi: ... It has also been shown that, while stimulating muscarinic cholinergic receptors in cultured pheochromocytoma cells increases ... shown that neuronal production of HCN activates NMDA receptors and plays a role in signal transduction between neuronal cells ( ...
Weber, E; Jilling T; Kirk K L (March 1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". J ... Weber E, Jilling T, Kirk KL (1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". J. Biol. ... "Identification of a rabphilin-3A-interacting protein as GTP cyclohydrolase I in PC12 cells". Biochem. Biophys. Res. Commun. 205 ... Inagaki N, Mizuta M, Seino S (February 1995). "Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells". J Biochem ...
2002). "Glycine transporter isoforms show differential subcellular localization in PC12 cells". J. Neurochem. 82 (1): 58-65. ... Reye P, Penfold P, Pow DV (2001). "Glyt-1 expression in cultured human Müller cells and intact retinae". Glia. 34 (4): 311-5. ... 2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". ... Cytogenet Cell Genet. 71 (3): 211. doi:10.1159/000134110. PMID 7587377. "Entrez Gene: SLC6A9 solute carrier family 6 ( ...
2002). "Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells". J. Neurochem. 82 (6): 1406-15. doi: ... "Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells". J. Neurochem. 82 (6): 1406-15. doi:10.1046/ ...
1998). "The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells". J. Cell Biol. 142 (4): 1075- ... doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573. v t e (Articles with short description, Short description matches ... 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635-48. ... Mol Cell Biol. 16 (7): 3545-53. doi:10.1128/MCB.16.7.3545. PMC 231349. PMID 8668170. Kirsch KH, Korradi Y, Johnson JP (Jul 1996 ...
Maruyama Y, Suzuki Y, Kazusaka A, Fujita S (June 2001). "Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells ... via vesicular monoamine transporter and its secretion by membrane depolarization or purinoceptor stimulation in PC12 cells". ...
in an experiment with PC12 cells and its name is non-acronymic. VGF gene encodes a precursor which is divided by proteolysis to ... "Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression". Cell Stem ... and paracrine roles in feedback loops between differentiated glioblastoma cells and glioblastoma-specific cancer stem cells, ... Cell. 22 (4): 514-528.e5. doi:10.1016/j.stem.2018.03.011. PMC 5947947. PMID 29625067. (Articles with short description, Short ...
Meng, X; Shi, J; Peng, B; Zou, X; Zhang, C (2006). "Effect of mouse Sim2 gene on the cell cycle of PC12 cell". Cell Biology ... When the SIM2 gene is transfected into PC12 cells, it affects the normal cycle of cell maturation. SIM2 inhibits the expression ... Comparing normal human breast cells to human breast cancer cells with immunohistochemical staining showed that SIM2s was ... which in turn inhibits the cell's ability to pass through the G1/S checkpoint and suppresses the cell's proliferation ability. ...
"Lack of effects of typical and atypical antipsychotics in DARPP-32 and NCS-1 levels in PC12 cells overexpressing NCS-1". ... "Lack of effects of typical and atypical antipsychotics in DARPP-32 and NCS-1 levels in PC12 cells overexpressing NCS-1". ... "Downregulation of the cAMP/PKA pathway in PC12 cells overexpressing NCS-1". Cellular and Molecular Neurobiology. 31 (1): 135-43 ... "Downregulation of the cAMP/PKA pathway in PC12 cells overexpressing NCS-1". Cellular and Molecular Neurobiology. 31 (1): 135-43 ...
August 2003). "IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells". Cell Death and ... Edwards L, Ernsberger P (August 2003). "The I(1)-imidazoline receptor in PC12 pheochromocytoma cells reverses NGF-induced ERK ... a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration". The Journal of Cell Biology. 151 ... In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth ...
PFOSA was the most toxic perfluorinated compound in a study with PC12 cells. Concentrations ranged from 10 to 250 micromolar in ... Fields S (June 2008). "Brain Effects Stick Around: PFCs and Neural Cell Development". Environ. Health Perspect. 116 (6): A258. ...
2002). "Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells". J. Biol. Chem. 277 (42): 39673-8. doi: ... "Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells ... Cell. 16 (2): 470-82. doi:10.1091/mbc.E04-08-0685. PMC 545880. PMID 15563604. Ross MT, Grafham DV, Coffey AJ, et al. (2005). " ... Cell. Biol. 22 (15): 5518-26. doi:10.1128/MCB.22.15.5518-5526.2002. PMC 133943. PMID 12101244. Fukuda M, Kanno E, Saegusa C, et ...
"Protective effect of diallyl disulfide on oxidative stress-injured neuronally differentiated PC12 cells". Molecular Brain ... Diallyl disulfide affects cancer cells much more strongly than normal cells. It also results in a strong and dose-dependent ... Garlic therefore supports, for example, the detoxification function of liver cells in vitro and protects nerve cells from ... The latter is reduced by diallyl disulfide by assisting in the detoxification of the cell, as well as some other mechanisms. By ...