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*  Theiler's disease
The prothrombin time (PT) and partial thromboplastin time (PTT) is often prolonged. Subclinical horses may only show elevated ... Decreases in the SDH and prothrombin time along with improvement in appetite are the best positive predictive indicators of ...
*  Thromboelastography
More common tests of blood coagulation include prothrombin time (PT,INR) and partial thromboplastin time (aPTT) which measure ... However, if the R-time associated with the heparinase-added specimen is significantly shorter than the R-time of the patient's ... The R value represents the time until the first evidence of a clot is detected. The K value is the time from the end of R until ... Because the R value on the TEG represents the time it takes for clot formation to start, it is a reflection of coagulation ...
*  Disseminated intravascular coagulation
Prolongation of the prothrombin time (PT) and the activated partial thromboplastin time (aPTT) reflect the underlying ... At the same time, thrombocytopenia occurs and this has been attributed to the entrapment and consumption of platelets. Clotting ...
*  Lupus anticoagulant
... tend to delay in-vitro coagulation in phospholipid-dependent laboratory tests such as the partial thromboplastin time. The ... such as the dilute Russell's viper venom time, or the Kaolin clotting time. Excess phospholipid will eventually correct the ... However, if the clotting time of the mixed plasma corrects towards normal, the diagnosis of an inhibitor such as the lupus ... The presence of prolonged clotting times on a routine plasma test often triggers functional testing of the blood clotting ...
*  Mixing study
... or Partial thromboplastin time (PTT) result. If the problem is a simple factor deficiency, mixing the patient plasma 1:1 with ... Some inhibitors are time dependent. In other words, it takes time for the antibody to react with and inactivate the added ... Performing a thrombin time on the test plasma can provide useful additional information for the interpretation of mixing tests ... Prednisone will often lower the titer over time. Intravenous immunoglobulin has been reported to also help but it does not seem ...
*  Partial thromboplastin time
The partial thromboplastin time (PTT) or activated partial thromboplastin time (aPTT or APTT) is a medical test that ... Partial thromboplastin time (PTT) measures the overall speed at which blood clots by means of two consecutive series of ... The partial thromboplastin time (PTT) is used in conjunction with another measure of how quickly blood clotting takes place ... The blood is mixed, then centrifuged to separate blood cells from plasma (as Partial thromboplastin time is most commonly ...
*  Tissue factor
... or activated partial thromboplastin time. It was not until much later that the subcomponents of thromboplastin and partial ... thromboplastin was a lab reagent, usually derived from placental sources, used to assay prothrombin times (PT time). ... When manipulated in the laboratory, a derivative could be created called partial thromboplastin, which was used to measure the ... whereas partial thromboplastin does not contain tissue factor. Tissue factor is not needed to activate the intrinsic pathway. ...
*  Heparin
Partial thromboplastin time should not be confused with prothrombin time, or PT, which measures blood clotting time through a ... The effects of heparin are measured in the lab by the partial thromboplastin time (aPTT), one of the measures of the time it ... These include activated partial thromboplastin time (APTT) and antifactor Xa activity. The specimen of choice is usually fresh ... Monitoring of the activated partial thromboplastin time is also not required and does not reflect the anticoagulant effect, as ...
*  KLKB1
Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. KLKB1 has been shown to ...
*  Factor XII deficiency
Specifically prothrombin time (PT) or activated partial thromboplastin time(aPTT) are prolonged. The diagnosis is confirmed by ...
*  Celecoxib
... does not usually affect prothrombin time, partial thromboplastin time or platelet counts; it does not inhibit ... Use the lowest effective dose for the shortest duration of time, consistent with individual patient goals, to reduce risk of GI ... Use the lowest effective dose for the shortest duration of time, consistent with individual patient goals, to reduce risk of ... Celecoxib is approximately 10-20 times more selective for COX-2 inhibition over COX-1. It binds with its polar sulfonamide side ...
*  Waldenström's macroglobulinemia
Prothrombin time, activated partial thromboplastin time, thrombin time, and fibrinogen tests should be performed. Platelet ... For a time, WM was considered to be related to multiple myeloma because of the presence of monoclonal gammopathy and ... At times, patients with Waldenström's macroglobulinemia may exhibit more than one M protein. Plasma viscosity must be measured ... Older diagnosis and treatments resulted in published reports of median survival of approximately 5 years from time of diagnosis ...
*  Liver disease
... partial thromboplastin time. Imaging tests such as transient elastography, ultrasound and magnetic resonance imaging can be ... By the time accumulating epigenetic and mutational changes eventually cause hepatocellular carcinoma, epigenetic alterations ... serum proteins, serum albumin, serum globulin, alanine transaminase, aspartate transaminase, prothrombin time, ...
*  Factor X deficiency
Typical are normal thrombin time, prolonged prothrombin time (PT) and prolonged partial thromboplastin time(PTT). FX antigen ...
*  Kaolin clotting time
Dilute Russell's viper venom time Partial thromboplastin time Tissue thromboplastin inhibition test Radhakrishnan, Kottayam ( ... KCT is similar to the activated partial thromboplastin time test, except it does not use exogenous phospholipid. Thus, a ... "Kaolin Clotting Time [KCT]". Retrieved 26 November 2014. Margolis, J (1958). "The kaolin clotting time; a rapid one-stage ... Kaolin clotting time (KCT) is a sensitive test to detect lupus anticoagulants. There is evidence that suggests it is the most ...
*  Pseudo gray platelet syndrome
Bleeding time, activated partial thromboplastin time, prothrombin time, and euglobulin lysis time were within normal limits. ...
*  Von Willebrand disease
... activated partial thromboplastin time-APTT, prothrombin time with International Normalized Ratio-PTINR, thrombin time-TT, and ... von Willebrand disease typically display a normal prothrombin time and a variable prolongation of partial thromboplastin time. ... Since this time, the factor causing the long bleeding time was called the "von Willebrand factor" in honor of Dr. Erik von ... A platelet function assay may give an abnormal collagen/epinephrine closure time, and in most cases, a normal collagen/ADP time ...
*  Prothrombin time
Partial thromboplastin time (PTT), or activated partial thromboplastin time (aPTT or APTT) Thrombin time (TT) ... It is used in conjunction with the activated partial thromboplastin time (aPTT) which measures the intrinsic pathway and common ... Jackson CM, Esnouf MP (March 2005). "Has the time arrived to replace the quick prothrombin time test for monitoring oral ... The prothrombin time is the time it takes plasma to clot after addition of tissue factor (obtained from animals such as rabbits ...
*  Factor VII deficiency
Typical is a discordance between the prolonged prothrombin time (PT) and normal levels for the activated partial thromboplastin ...
*  Fibrinogen
Blood clotting is measured using standard tests, e.g. prothrombin time, partial thromboplastin time, thrombin time, and/or ... This accumulation leads over time to one form of familial renal amyloidosis. Plasma fibrinogen levels are similar to that seen ... reptilase time; low fibrinogen levels and dysfunctional fibrinogens usually prolong these times whereas the lack of fibrinogen ... i.e. afibrinogenemia) renders these times infinitely prolonged. Antigenic levels of fibrinogen levels are measured in the ...
*  Hypercoagulability in pregnancy
It can prolong the partial thromboplastin time (APTT) in some women, but still, the APTT is not useful for monitoring. To check ... Pregnancy changes the plasma levels of many clotting factors, such as fibrinogen, which can rise up to three times its normal ... LMWH therapy does not affect the prothrombin time (PT) or the INR, and anti-Xa levels are not reliable. ... of therapy If the therapy duration reaches delivery time, the remaining duration may be given after delivery, possibly ...
*  Waterhouse-Friderichsen syndrome
Thrombocytopenia is sometimes extreme, with alteration in prothrombin time (PT) and partial thromboplastin time (PTT) ...
*  Seratrodast
... time to occlusion and bleeding time. Seratrodast has no effect on prothrombin time and activated partial thromboplastin time, ...
*  High-density lipoprotein
... in this study revealed that there was a significant negative correlation between HDL and activated partial thromboplastin time ... The lowest incidence of atherosclerotic events over time occurs within those with both the highest concentrations of total HDL ... Benatar JR, Stewart RA (2007). "Is it time to stop treating dyslipidaemia with fibrates?". The New Zealand Medical Journal. 120 ...
*  Hypoprothrombinemia
Lab exams revealed prolonged prothrombin time (PT) of 34.4 and acquired partial thromboplastin time (aPTT) of 81.7, as well as ... No abnormality in fibrinogen, liver function test, and bleeding time. However, prothrombin levels were less than 1% so patient ...
*  Abdominal mass
... partial thromboplastin time (PTT), serum amylase and total bilirubin (TBIL). If late-stage liver disease is suspected, then a ...
*  Factor V Leiden
"Comparison of Russell viper venom-based and activated partial thromboplastin time-based screening assays for resistance to ... In both methods, the time it takes for blood to clot is decreased in the presence of the factor V Leiden mutation. This is done ... People who inherit two copies of the mutation (homozygous), one from each parent, may have up to 80 times the usual risk of ... Most laboratories screen 'at risk' patients with either a snake venom (e.g. dilute Russell's viper venom time) based test or an ...