Oxymorphone
... ER Tablets should be taken on an empty stomach. Oxymorphone was marketed by Endo Pharmaceuticals, under the brand ... Oxymorphone is also a minor metabolite of oxycodone, which is formed by CYP2D6-mediated O-demethylation. Oxymorphone was first ... Oxymorphone is 10 times more potent than morphine. The calculation of relative potency indicated that 1 mg of oxymorphone ... Like oxycodone, which metabolizes to oxymorphone, oxymorphone has a high potential to be abused. It was developed in Germany in ...
Oxymorphone-3-methoxynaltrexonazine
Naloxonazine Naloxone Naltrexone Oxymorphone Galetta S, Hahn EF, Nishimura S, Pasternak GW (August 1987). "Oxymorphone- ... Oxymorphone-3-methoxynaltrexonazine (OM-3-MNZ) is a morphinan-based opioid that acts as a selective μ-opioid receptor agonist, ...
Regulation of therapeutic goods
... hydromorphone and oxymorphone; codeine relatives: hydrocodone and oxycodone; synthetic opioids: pethidine, methadone, fentanyl ...
Opiate
Oxymorphone is a congener of morphine. It is metabolized to 6-hydroxy-oxymorphone and oxymorphone-3-glucuronide, and 40% is ... Oxymorphone-3-glucuronide's activity is unknown. Opiates are mainly used for pain management with the premise that there will ... oxymorphone, metopon, and possibly other derivatives of morphine and/or hydromorphone also are found in trace amounts in opium ...
7-Spiroindanyloxymorphone
It is a derivative of oxymorphone. Portoghese PS, Moe ST, Takemori AE (August 1993). "A selective delta 1 opioid receptor ... Fang X, Larson DL, Portoghese PS (September 1997). "7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and ... "7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors". Journal of Medicinal ... agonist derived from oxymorphone. Evidence for separate recognition sites for delta 1 opioid receptor agonists and antagonists ...
Prohibition of drugs
... and oxymorphone (Opana). Sedatives such as GHB and methaqualone (Quaalude) Stimulants such as cocaine, amphetamine (Adderall), ...
3,14-Diacetyloxymorphone
3,6-Diacetyloxymorphone is a third acetylated oxymorphone derivative, the oxymorphone analogue of acetylmorphone and expected ... As an ester of oxymorphone, it is presumably a Schedule II controlled substance as it and its relatives save acetylmorphone do ... Each of the acetyl esters of oxymorphone has a hydromorphone analogue, and these were all developed around the same time (1915- ... It is an acetyl derivative of oxymorphone. It is related to other acetylated morphone derivatives, including 3,6- ...
UFC 138
Leben tested positive for oxycodone and oxymorphone. This bout aired on the broadcast following the Muñoz vs Leben bout. This ...
Nalmexone
Nalbuphine Oxymorphone Naloxone Naltrexone Pentazocine Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. ... Loew GH, Berkowitz DS (1978). "Quantum chemical studies of N-substituent variation in the oxymorphone series of opiate ...
Anderson Silva
Irvin later tested positive for methadone and oxymorphone. Silva's next fight was on 25 October 2008, at UFC 90 in Rosemont, ... MMAjunkie Staff (29 July 2008). "NSAC: UFC's James Irvin tests positive for methadone and oxymorphone". MMA Junkie. Retrieved ...
James Irvin (fighter)
Afterwards, Irvin tested positive for methadone and oxymorphone. Irvin subsequently admitted to taking the drugs, stating that ... MMAjunkie Staff (July 29, 2008). "NSAC: UFC's James Irvin tests positive for methadone and oxymorphone". MMA Junkie. Retrieved ...
UGT2B7
Pergolizzi JV, Raffa RB, Gould E (September 2009). "Considerations on the use of oxymorphone in geriatric patients". Expert ...
Oxymorphazone
... is an opioid analgesic drug related to oxymorphone. Oxymorphazone is a potent and long acting μ-opioid agonist ... This gives it an unusual pharmacological profile, and while oxymorphazone is only around half the potency of oxymorphone, with ...
List of doping cases in sport (I)
UK Anti-Doping Written Decision[permanent dead link]. "NSAC: UFC's James Irvin tests positive for methadone and oxymorphone". ...
UFC Fight Night: Silva vs. Irvin
After the fight, Irvin tested positive for methadone and oxymorphone. This card was put together on an unusually short notice, ... NSAC: UFC's James Irvin tests positive for methadone and oxymorphone , MMAjunkie.com Archived 2012-07-20 at archive.today "UFC ...
Intractable pain
Examples include morphine, hydromorphone, oxymorphone, hydrocodone, oxycodone, codeine, and buprenorphine. methadone - ...
Controlled Substances Act
Oxymorphone (semi-synthetic opioid; active ingredient in Opana) Nembutal (Pentobarbital) - barbiturate medication originally ...
Analgesic
"Opana, Opana ER (oxymorphone) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. ...
Oxycodone
... of the metabolism of oxymorphone, making oxymorphone-3-glucuronide the main metabolite of oxymorphone, while the latter two ... Oxymorphone is also further metabolized, as follows: 3-Glucuronidation to oxymorphone-3-glucuronide predominantly via UGT2B7 6- ... Oxymorphone plays only a minor role, being responsible for 15.8% and 4.5% of the analgesic effect of oxycodone after oral and ... Oxymorphone possesses 3- to 5-fold higher affinity for the MOR than does oxycodone, while noroxycodone and noroxymorphone ...
Drug test
However, most opioid tests will not reliably detect oxycodone, oxymorphone, meperidine, or fentanyl. Likewise, most ...
Karo Parisyan
Following the fight, Parisyan tested positive for banned painkillers hydrocodone, hydromorphone and oxymorphone. Parisyan has ...
Oxymorphol
... is oxymorphone which has been hydrogenated at the 6-position and consists of a mixture of 4,5α-Epoxy-17- ... α-Oxymorphol as "Hydromorphinol" Cone EJ, Darwin WD, Buchwald WF, Gorodetzky CW (1983). "Oxymorphone metabolism and urinary ... It is produced by the human body as an active metabolite of oxymorphone and some bacteria as an intermediate in turning ...
Justin Levens
He tested positive for oxymorphone before the fight and was suspended until January 2009. Friend Tom Atencio said Levens was ...
1914
Oxymorphone, a powerful narcotic analgesic closely related to morphine, is first developed in Germany. The first everyday items ...
Laudanum
Dong Hyun Kim
Afterwards, however, Parisyan tested positive for three banned pain killers: Hydrocodone, Hydromorphone and Oxymorphone. The ...
1914 in science
Oxymorphone, a powerful narcotic analgesic closely related to morphine, is first developed in Germany. T. W. Richards finds ...
Semorphone
... (Mr 2264) is an opiate analogue that is an N-substituted derivative of oxymorphone. Semorphone is a partial agonist ... although it might be considered to be a controlled substance analogue of oxymorphone on the grounds of its related chemical ...
Grapefruit-drug interactions
Oxymorphone AUC(0-∞) increased by 1.6-fold but the metabolite-to-parent ratio remained unchanged. Quetiapine (Seroquel) ...
Opioid
The first, oxymorphone, was synthesized from thebaine, an opioid alkaloid in opium poppies, in 1914. Next, Martin Freund and ... oxymorphone, ethylmorphine and buprenorphine; Fully synthetic opioids: such as fentanyl, pethidine, levorphanol, methadone, ... Oxymorphone Fentanyl (see also list of fentanyl analogues) Alphamethylfentanyl Alfentanil Sufentanil Remifentanil Carfentanyl ...