It is generally known that ketone oximes can be deprotonated and alkylated regiospecifically syn to the oxime hydroxy group. It ... The use of CaO as a base in the preparation of oximes from various types of ketones and aldehydes under mild conditions also ... "Oximes - Encyclopedia". "Acetaldoxime". Sharghi, H., & Sarvari, M. H.. A mild and versatile method for the preparation of ... It is one of the simplest oxime-containing compounds, and has a wide variety of uses in chemical synthesis. Acetaldoxime will ...
L.; Malekin, S. I.; Martynov, I. V. (1972). "Phosphorylated oximes. XII. Reactions of 2-halophospholanes with ... "Effect of Alkyl Substituents in Phosphorylated Oximes". Zhurnal Obshchei Khimii. 57 (12): 2720-2723. Raevskii, O. A.; Grigor'ev ...
The isomerism of the oximes. Part XXXIII. The oximes of opianic acid and of phthalic anhydride". J. Chem. Soc.: 529-539. doi: ... Three possibilities were discussed and are shown in the Figure below: a mono-oxime of phthalic anhydride ("phthaloxime", I), an ... Porcheddu, Andrea; Giacomelli, Giampaolo (2009). "Synthesis of oximes and hydroxamic acids". In Rappaport, Zvi; Lieberman, Joel ... Beckmann rearrangement of cyclohexanone oxime with sulfuric acid). Alkanes are converted into nitroalkanes in the presence of ...
It reduces oximes to imines. Titanium trichloride can reduce nitrate to ammonium ion thereby allowing for the sequential ...
For people afflicted with cholinergic syndrome, atropine sulfate combined with an oxime is used to combat the effects of the ... Atropine can be used as an antidote in conjunction with pralidoxime or other pyridinium oximes (such as trimedoxime or ... Experience of nerve agents and acute pesticide poisoning on the effects of oximes". Journal of Physiology. 92 (5-6): 375-378. ... Peter JV, Moran JL, Graham P (February 2006). "Oxime therapy and outcomes in human organophosphate poisoning: an evaluation ...
Jokanović M, Prostran M (2009). "Pyridinium oximes as cholinesterase reactivators. Structure-activity relationship and efficacy ... belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to ... "Current understanding of the application of pyridinium oximes as cholinesterase reactivators in treatment of organophosphate ...
... is a member of the oxime family used to treat nerve gas poisoning. Oximes are drugs known for their ability to ... giving more time to apply the oxime. Jokanović M, Prostran M (2009). "Pyridinium oximes as cholinesterase reactivators. ... Oximes like these do have side effects and they include liver damage, kidney damage, nausea, vomiting, but they are very ... Oximes such as obidoxime, pralidoxime and asoxime (HI-6) are used to restore enzyme functionality. They have greater affinity ...
Oxime reduction Oximes Leuckart reaction Ketones and aldehydes Reductive amination with formic acid and ammonia via an imine ...
The Oxidation of Oximes to Nitroparaffins". J. Am. Chem. Soc. 77 (17): 4557-4559. doi:10.1021/ja01622a036. CS1 maint: ... In the case of nitrogen-containing compounds, known transformations include oximes and aromatic primary amines to nitro ...
Buckley, Nick A.; Eddleston, Michael; Li, Yi; Bevan, Marc; Robertson, Jane (2011). "Oximes for acute organophosphate pesticide ... Poisoning is treated with atropine and simultaneously with oximes such as pralidoxime. Atropine blocks acetylcholine from ... Pralidoxime is intended to reactivate acetylcholinesterase, but the benefit of oxime treatment is questioned. A randomized ...
Oxidation of oximes or primary amines. Reduction of β-nitro alcohols or nitroalkenes. By decarboxylation of α-nitro carboxylic ... Olah, George A.; Ramaiah, Pichika; Chang-Soo, Lee; Prakash, Surya (1992). "Convenient Oxidation of Oximes to Nitro Compounds ...
CS1 maint: discouraged parameter (link) Iffland, Don C.; Criner, G. X. (1953). "Preparation of Nitro Compounds from Oximes. II ...
This π-complex is not found in the H3O+(H2O)6. With the cyclohexanone-oxime, the relief of ring strain results in a third ... Cyclic oximes and haloimines yield lactams. The Beckmann rearrangement is often catalyzed by acid, however other reagents have ... The rearrangement of acetone oxime in the Beckmann solution involved three acetic acid molecules and one proton (present as an ... When the group α to the oxime is capable of stabilizing carbocation formation, the fragmentation becomes a viable reaction ...
Kalia, J.; Raines, R. T. (2008). "Hydrolytic stability of hydrazones and oximes". Angew. Chem. Int. Ed. 47 (39): 7523-6. doi: ... Kölmel, Dominik K.; Kool, Eric T. (2017). "Oximes and Hydrazones in Bioconjugation: Mechanism and Catalysis". Chemical Reviews ... to 103-fold more sensitive to hydrolysis than analogous oximes. When derived from hydrazine itself, hydrazones condense with a ...
By: Kiriki, Satoshi.Aug 3, 2015.JP 2015140302 Torisawa, Yasuhiro (15 January 2007). "Conversion of indanone oximes into ...
Dehydration of amides and oximesEdit. Nitriles can be prepared by the dehydration of primary amides. In the presence of ethyl ...
The oxime is treated with Grignard reagents: Hoch, Compt. rend., 196, 1865 (1934); (a), ibid., aOS, 799 (1936); (e), ibid., 204 ... Kenneth N. Campbell; Barbara Knapp Campbell; Elmer Paul Chaput (1943). "The reaction of Grignard reagents with oximes. ii. The ... In organic chemistry the Hoch-Campbell ethylenimine synthesis is a method for constructing ethyleneimines from oximes. ... "The action of Grignard reagents on oximes. iii. The mechanism of the action of arylmagnesium halides on mixed ketoximes. A new ...
"Selective reductive dimerization of homocubane series oximes". Russian Journal of Organic Chemistry. 47 (11): 1695-1702. doi: ...
In the treatment of nerve agent poisoning, atropine is most often administered along with a Hagedorn oxime such as pralidoxime ... monofluorophosphate). The organic groups are subject to more variety; however, a common substituent is phosgene oxime or ... Effect of Alkyl Substituents in Phosphorylated Oximes. Zhurnal Obshchei Khimii. 1987; 57(12):2720-2723. Peplow, Mark (19 March ...
Galli, C. (2009). "Nitroxyl radicals". Chemistry of Hydroxylamines, Oximes and Hydroxamic Acids. 2. John Wiley & Sons. pp. 705- ...
Schmitz, E.; Ohme, R. (1964). "Isomere Oxime mit Dreiringstruktur". Chem. Ber. 97 (9): 2521. doi:10.1002/cber.19640970916. ...
The active ingredient in pepper spray is capsaicin, which is a chemical derived from the fruit of plants in the genus Capsicum, including chilis. Extraction of oleoresin capsicum (OC) from peppers requires capsicum to be finely ground, from which capsaicin is then extracted using an organic solvent such as ethanol. The solvent is then evaporated, and the remaining waxlike resin is the oleoresin capsaicin. An emulsifier such as propylene glycol is used to suspend OC in water, and pressurized to make it aerosol in pepper spray. High performance liquid chromatography (HPLC) is used to measure the amount of capsaicin and major capsaicinoids within pepper sprays. Determining the strength of different manufacturers of pepper sprays can be confusing and difficult. Statements a company makes about their product strength are not regulated. A method using the capsaicin and related capsaicinoids (CRC) content of the product is unreliable as well, because there are six different types of capsaicinoids, ...
Chemical, biological (CB) - and sometimes radiological - warfare agents were assigned what is termed a military symbol by the U.S. military until the American chemical and biological weapons programs were terminated (in 1990 and 1969, respectively). Military symbols applied to the CB agent fill, and not to the entire weapon. A chemical or biological weapon designation would be, for example, "Aero-14/B", which could be filled with GB, VX, TGB, or with a biological modification kit - OU, NU, UL, etc. A CB weapon is an integrated device of (1) agent, (2) dissemination means, and (3) delivery system. Military symbols evolved out of the First World War from the British in part for secrecy, and to simplify reference to chemicals by something other than a chemical name. These symbols were sometimes applied as marking on weapons to indicate the agent contents. Military symbols constantly changed and had transitory definitions. For example, mustard gas was assigned the military symbol originally HS for ...
GV (IUPAC name: 2-(Dimethylamino)ethyl N,N-dimethylphosphoramidofluoridate) is an organophosphate nerve agent. GV is a part of a new series of nerve agents with properties similar to both the "G-series" and "V-series". It is a potent acetylcholinesterase inhibitor with properties similar to other nerve agents, being a highly poisonous vapour. Treatment for poisoning with GV involves drugs such as atropine, benactyzine, obidoxime, and HI-6.[1][2] ...
Scheele observed several of the properties of chlorine: the bleaching effect on litmus, the deadly effect on insects, the yellow-green color, and the smell similar to aqua regia.[8] He called it "dephlogisticated muriatic acid air" since it is a gas (then called "airs") and it came from hydrochloric acid (then known as "muriatic acid").[7] He failed to establish chlorine as an element.[7] Common chemical theory at that time held that an acid is a compound that contains oxygen (remnants of this survive in the German and Dutch names of oxygen: sauerstoff or zuurstof, both translating into English as acid substance), so a number of chemists, including Claude Berthollet, suggested that Scheele's dephlogisticated muriatic acid air must be a combination of oxygen and the yet undiscovered element, muriaticum.[9][10] In 1809, Joseph Louis Gay-Lussac and Louis-Jacques Thénard tried to decompose dephlogisticated muriatic acid air by reacting it with charcoal to release the free element muriaticum (and ...
An article in the Annals of Emergency Medicine compared the sedating dose and the toxic or lethal dose of fentanyl and its derivatives, and found that while carfentanil and remifentanil have dramatically shorter biological half-lives and are more potent than fentanyl, both of those drugs are readily taken up into body fat and can re-enter the circulation after an overdose is first treated, causing severe delayed effects and even death if the correct antidote is not administered quickly when the drugs act again. This might account for the large number of deaths following use of large amounts of Kolokol-1 in a closed space like the Barricade Theatre], where the gas might have been unexpectedly concentrated in areas of the theater.. Under the heading "Lessons Learned," the authors state "It seems likely that the 800 hostages were about to be killed by Chechen rebels. To rescue them, the Russian military used a calmative agent in an attempt to subdue the rebels. The intent was likely to win control ...
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Phosgene oxime (CX). Blood agents[edit]. Main article: Blood agent. These substances are metabolic poisons that interfere with ...
The oxime ligation can then occur readily, and it has been reported that the rate increased up to 400 times under mild acidic ... They will then selectively condense with an alkoxyamine and a hydrazine, producing oxime and hydrazone derivatives (shown in ... Dirksen, A.; Hackeng, T. M.; Dawson, P. E. (2006). "Nucleophilic Catalysis of Oxime Ligation". Angewandte Chemie International ... Schmidt, Pascal; Stress, Cedric; Gillingham, Dennis (2015). "Boronic acids facilitate rapid oxime condensations at neutral pH ...
Trifexis also includes milbemycin oxime. Comfortis and Trifexis brands treat adult fleas on pets; the latter also prevents ...