Oxamic acid
... inhibits lactate dehydrogenase A. The active site of lactate dehydrogenase (LDH) is closed off once oxamic acid ... Oxamic acid is an organic compound with the formula NH2C(O)COOH. It is a white, water-soluble solid. It is the monoamide of ... Oxamic acid also has applications in polymer chemistry. It increases the water solubility of certain polymers, including ... Oxamate, the conjugate base of oxamic acid Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 ( ...
Oxamate
... is the carboxylate anion of oxamic acid. Oxamate has a molecular formula of C2H2NO3− and is an isosteric form of ... Salts and esters of oxamic acid are known collectively as oxamates. Oxamate is a competitive inhibitor of the enzyme lactate ... Oxamate also plays inhibiting roles with oxaloacetate, an important intermediate for the citric acid cycle. Oxamate competes ...
Discovery and development of neuraminidase inhibitors
They discovered that N-substituted oxamic acids had enzyme inhibitory properties. Then it was found that the synthetic compound ... N-acetylneuraminic acid (Neu5Ac) is one of the two most common sialic acid in mammals. It is a monosaccharide with a backbone ... Including a glutamic acid residue binding the C7 and C9 alcohol groups on the glycerol side-chain (at C6) with hydrogen bonds ... The three arginine residues that bind the C1 acid-group with salt bridges in vNEU are also present in hNEU. Active site ...
Tetraketopiperazine
Reacting sodium oxamate (the sodium salt of oxamic acid) with hydrochloric acid yields some tetraketopiperazine. A higher yield ... Glyoxalic acid and oxamide are side products. When heated tetraketopiperazine does not melt, but turns black at 250°C. ... Tetraketopiperazine is slightly soluble in water and more so in boiling acetic acid. The solid form has monoclinic prismatic ...
Oximide
In 1886 Ost and Mente claimed to produce oximide by the reaction of oxamic acid with phosphorus pentachloride (PCl5). However, ... Oximide is an unstable chemical compound, the cyclic imide of oxalic acid. Other names for this are the systematic name 2,3- ...
Antoine Jérôme Balard
In organic chemistry he published papers on the decomposition of ammonium oxalate, with formation of oxamic acid, on amyl ... crystals while he was working with tartaric acid.[citation needed] Balard died in Paris on 30 April 1876. While the discovery ...
List of MeSH codes (D02)
... oxamic acid MeSH D02.241.152.811 - uronic acids MeSH D02.241.152.811.325 - glucuronic acids MeSH D02.241.152.811.325.300 - ... quinic acid MeSH D02.241.511.852 - shikimic acid MeSH D02.241.511.902 - sugar acids MeSH D02.241.511.902.107 - ascorbic acid ... edetic acid MeSH D02.241.081.038.455 - egtazic acid MeSH D02.241.081.038.581 - iodoacetic acid MeSH D02.241.081.038.581.400 - ... hexuronic acids MeSH D02.241.081.844.915.400.500 - iduronic acid MeSH D02.241.081.901.177 - aconitic acid MeSH D02.241.081.901. ...