Osteonectin inhibits tumorigenesis in mice. Osteonectin can be classed as a myokine, as it was found that even a single bout of ... A novel myokine osteonectin, or SPARC (secreted protein acidic and rich in cysteine), plays a vital role in bone mineralization ...

2002). "Investigation of osteocalcin, osteonectin, and dentin sialophosphoprotein in developing human teeth". Bone. 30 (2): 377 ...

2002). "Investigation of osteocalcin, osteonectin, and dentin sialophosphoprotein in developing human teeth". Bone. 30 (2): 377 ...

"Entrez Gene: SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2". Nagase T, Seki N, Ishikawa K, ...

Osteonectin is a metal binding glycoprotein produced by many cell types including ECs. Lastly, endorepellin is a recently ... and osteonectin. All of these components of the basement membrane are substrates for MMP-2, 3, 7, and 9, among others. ...

"Entrez Gene: SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1". Périn JP, Alliel PM, Jollès P, ... 2006). "Significant overexpression of SPARC/osteonectin mRNA in pancreatic cancer compared to cancer of the papilla of Vater". ...

It probably is aided by its action in upregulating thrombospondin, SPARC (osteonectin), and fibronectin. However it has also ...

These proteins include platelet factor V, von Willebrand factor, fibrinogen, thrombospondin-1, and osteonectin. There is also a ...

Roach HI (June 1994). "Why does bone matrix contain non-collagenous proteins? The possible roles of osteocalcin, osteonectin, ...

... a matricellular glycoprotein and potential tumor-suppressor of the SPARC/BM-40/Osteonectin family". The International Journal ...

Some of the regulatory proteins in mineralized tissues are osteonectin, osteopontin, osteocalcin, bone sialoprotein and dentin ...

These genes include osteocalcin, osteopontin, bone sialoprotein, osteonectin, RANK ligand (NF-κB receptor activator) and ...

... and osteonectin from the mineral compartment of developing human bone". The Journal of Biological Chemistry. 262 (20): 9702-8. ...

... osteonectin, and alkaline phosphatase. Collagen type I counts for 90% of the protein mass. The inorganic part of bone is the ...

... and some other proteins like osteonectin, hnRNPs, calreticulin, cubilin, and megalin. Bovine serum albumin Serum albumin GRCh38 ...

... and Osteonectin (OSN) mRNA, all of which are highly expressed by osteoblasts. Osteoblast promoter activity is also higher in C4 ...

... and osteonectin. Defective function of cathepsin K therefore results in failure of normal degradation of the accumulated ...

... osteonectin, osteopontin and bone sialoprotein which are all necessary for productive osteoblasts during the creation of ...

... a database design standard Osteonectin, a glycoprotein also known as SPARC (secreted protein, acidic and rich in cysteine) ...

... also termed osteonectin]) gene, THBS2 (thrombospondin-2) gene, COL6A2 (collagen type VI alpha 2 chain) gene, SEC31A {SEC31 ...

... death of bone tissue Osteonectin, a glycoprotein ON Semiconductor, a semiconductor manufacturing company O'Nan group, a ...

... although osteofibrous dysplasia is more likely to show an immunohistochemical reaction to osteonectin, neurofibromin 1, and S- ...

Examples include: Fibronectin Laminin Osteonectin Glycocalyx Media related to Membrane glycoproteins at Wikimedia Commons ...

... causing a defect in the protein osteonectin, which leads to severe disease characterized by generalized platyspondyly, ...

... is also detectable in osteoid, bone matrix proper, and dentin. Osteonectin has been localized in a variety of ... Osteonectin has also been found to decrease DNA synthesis in cultured bone. High levels of immunodetectable osteonectin are ... Osteonectin also shows affinity for collagen in addition to bone mineral calcium. A correlation between osteonectin over- ... Osteonectin is a 40 kDa acidic and cysteine-rich glycoprotein consisting of a single polypeptide chain that can be broken into ...

Contractions of skeletal muscle fiber are caused due to electrical stimulation. This process is caused by the depolarization of the transverse tubular junctions. Once depolarized the sarcoplasmic reticulum (SR) releases Ca2+ into the myoplasm where it will bind to a number of calcium sensitive buffers. The Ca2+ in the myoplasm will diffuse to Ca2+ regulator sites on the thin filaments. This leads to the actual contraction of the muscle.[15] Contractions of smooth muscle fiber are dependent on how a Ca2+ influx occurs. When a Ca2+ influx occurs, cross bridges form between myosin and actin leading to the contraction of the muscle fibers. Influxes may occur from extracellular Ca2+ diffusion via ion channels. This can lead to three different results. The first is a uniform increase in the Ca2+ concentration throughout the cell. This is responsible for increases in vascular diameters. The second is a rapid time dependent change in the membrane potential which leads to a very quick and uniform ...