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*  Bone resorption
Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification. Osteocyte activity plays a ... Ethanol suppresses the activity and differentiation of osteoblasts. At the same time, it has a direct effect on osteoclast ... Oxidative stress results when ethanol induces NOX expression, resulting in ROS production in osteoblasts which can ultimately ... Direct effects of chronic alcoholism are apparent in osteoblasts, osteoclasts and osteocytes. ...
*  Osteocalcin
As osteocalcin is produced by osteoblasts, it is often used as a marker for the bone formation process. It has been observed ... Osteocalcin is secreted solely by osteoblasts and thought to play a role in the body's metabolic regulation and is pro- ... "Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells". Gene. 413 ( ... "General transcription factor IIA-gamma increases osteoblast-specific osteocalcin gene expression via activating transcription ...
*  Osteoclast
... which stated that osteoclasts and osteoblasts are of the same lineage, and osteoblasts fuse together to form osteoclasts. After ... It may be important to note that while osteoclasts are derived from the hematopoietic lineage, osteoblasts are derived from ... Osteoclast differentiation is inhibited by osteoprotegerin (OPG), which is produced by osteoblasts and binds to RANKL thereby ... Osteoclast activity is also mediated by the interaction of two molecules produced by osteoblasts, namely osteoprotegerin and ...
*  Osteoblast
The osteoblasts are also connected by gap junctions, small pores that connect osteoblasts, allowing the cells in one cohort to ... Osteoblasts are the major cellular component of bone. Osteoblasts arise from mesenchymal stem cells (MSC). MSC give rise to ... Osteoblasts buried in the matrix are called osteocytes. During bone formation, the surface layer of osteoblasts consists of ... A group of organized osteoblasts together with the bone made by a unit of cells is usually called the osteon. Osteoblasts are ...
*  Osteoblast milk protein
... (OMP, Chinese: 造骨牛奶蛋白) is the name used by Mengniu, a Chinese dairy company, for a milk protein used as ... It is supposed to help the absorption of calcium and promote bone growth in the osteoblasts and prevent osteoporosis. In ...
*  Endochondral ossification
o. Layer of osteoblasts. im. Subperiosteal bony deposit. (From Quain's "Anatomy," E. A. Schäfer.) Intramembranous ossification ... Formation of bone collar The osteoblasts secrete osteoid against the shaft of the cartilage model (Appositional Growth). This ... The periosteum contains a layer of undifferentiated cells (osteoprogenitor cells) which later become osteoblasts. ...
*  Ossification
... (or osteogenesis) in bone remodeling is the process of laying down new bone material by cells called osteoblasts. ... It invades the primary centre of ossification, bringing osteogenic cells (osteoblasts on the outside, osteoclasts on the inside ... Caetano-Lopes J, Canhão H, Fonseca JE (2007). "Osteoblasts and bone formation". Acta reumatológica portuguesa. 32 (2): 103-10. ... depositing osteoblasts and osteoclasts which erode the cartilage and build bone. This occurs at both ends of long bones but ...
*  ATF4
Terminal osteoblast differentiation, represented by matrix mineralization, is significantly inhibited by the inactivation of ... ATF4 transcription factor is also known to play role in osteoblast differentiation along with RUNX2 and osterix. ... "Transcriptional regulation of osteoblasts". Cells, Tissues, Organs. 189 (1-4): 144-52. doi:10.1159/000151747. PMC 3512205 . ... "JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation". Journal of Bone and Mineral Research ...
*  Osteocyte
10-20% of osteoblasts differentiate into osteocytes. Those osteoblasts on the bone surface that are destined for burial as ... some of which differentiate into active osteoblasts. Osteoblasts/osteocytes develop in mesenchyme. In mature bone, osteocytes ... As the osteoblast transitions to an osteocyte, alkaline phosphatase is reduced, and casein kinase II is elevated, as is ... When osteoblasts become trapped in the matrix that they secrete, they become osteocytes. Osteocytes are networked to each other ...
*  Bone
When the osteoblast becomes trapped, it becomes known as an osteocyte. Other osteoblasts remain on the top of the new bone and ... First, the osteoblast puts up collagen fibers. These collagen fibers are used as a framework for the osteoblasts' work. The ... Osteoblasts also manufacture hormones, such as prostaglandins, to act on the bone itself. The osteoblast creates and repairs ... The brand new bone created by the osteoblast is called osteoid. Once the osteoblast is finished working it is actually trapped ...
*  Extracellular matrix
Osteoblasts are responsible for bone formation. Plant cells are tessellated to form tissues. The cell wall is the relatively ... Kern B, Shen J, Starbuck M, Karsenty G (2001). "Cbfa1 contributes to the osteoblast-specific expression of type I collagen ...
*  HIVEP3
It regulates osteoblasts. HIVEP3 has been shown to interact with TRAF1 and TRAF2. GRCh38: Ensembl release 89: ENSG00000127124 ...
*  Eldecalcitol
... where the body constantly maintains this calcium homeostasis through osteoblast and osteoclast activity. Osteoblast activity ... Matsuo, K; Irie, N (2008). "Osteoclast-osteoblast communication". Archives of Biochemistry and Biophysics. 473 (2): 201-209. ... while still able to maintain osteoblast function so as to not hinder bone formation. Unlike other vitamin D analogs, ...
*  Bone remodeling
Osteoblasts actively synthesizing osteoid containing two osteocytes. Osteoclast, with bone below it, showing typical ... Two main types of cells are responsible for bone metabolism: osteoblasts (which secrete new bone), and osteoclasts (which break ... followed by deposition of bone by osteoblasts. Together, the cells that are responsible for bone remodeling are known as the ...
*  Mir-367 microRNA precursor family
"Medpor regulates osteoblast's microRNAs". Bio-Medical Materials and Engineering. 18 (2): 91-7. PMID 18408260. Yue J, Sheng Y, ...
*  Mir-337 microRNA precursor family
"Differences in osteoblast miRNA induced by cell binding domain of collagen and silicate-based synthetic bone". Journal of ... Regulates Osteoblast RNA Interfering". Journal of Prosthodontics. 17 (7): 522-526. doi:10.1111/j.1532-849X.2008.00331.x. PMID ... "Medpor regulates osteoblast's microRNAs". Bio-medical materials and engineering. 18 (2): 91-97. PMID 18408260. Palmieri, A.; ... "Peptide-15 Changes miRNA Expression in Osteoblast-Like Cells". Implant Dentistry. 17 (1): 100-108. doi:10.1097/ID. ...
*  Mir-32 microRNA precursor family
"Medpor regulates osteoblast's microRNAs". Bio-medical materials and engineering. 18 (2): 91-97. PMID 18408260. Choong, M. L.; ...
*  Mir-153 microRNA precursor family
"Medpor regulates osteoblast's microRNAs". Bio-medical materials and engineering. 18 (2): 91-97. PMID 18408260. Song, L; Duan, P ...
*  Adenosine receptor
Similarly to A2A receptor, the A2B receptor promotes osteoblast differentiation. The osteoblast cell is derived from the ... The role of A2A receptor opposes that of A1 in that it inhibits osteoclast differentiation and activates osteoblasts. Studies ... The cell signalling involved in the stimulation of the A2B receptor directs the route of differentiation to osteoblast, rather ... doi:10.1017/erm.2013.2 Carroll SH, Ravid K (2013) Differentiation of mesenchymal stem cells to osteoblasts and chondrocytes: a ...
*  Cell potency
MSCs can differentiate into osteoblasts, chondrocytes, and adipocytes. In biology, oligopotency is the ability of progenitor ...
*  Staurosporine
"Molecular mechanism of staurosporine-induced apoptosis in osteoblasts". Pharmacological Research. 42 (4): 373-381. doi:10.1006/ ...
*  Synaptophysin
"Evidence for targeted vesicular glutamate exocytosis in osteoblasts". Bone. 29 (1): 16-23. doi:10.1016/S8756-3282(01)00482-3. ...
*  Osteonecrosis of the jaw
while the average lifespan of human osteoclasts is about 2 to 6 weeks and the average lifespan of osteoblasts is approximately ... Diseased or damaged bone is resorbed through the osteoclasts mediated process while osteoblasts form new bone to replace it, ... Experimental evidence suggests that bone cells composed of osteocytes, osteoclasts, and osteoblasts die within 12-48 hours, and ... Second, mesenchymal cells differentiate into osteoblasts or fibroblasts. Under favorable conditions, layers of new bone form on ...
*  Drynaria
on Osteoblastic Proliferation Using an Osteoblast-Like Cell Line". Chem. Pharm. Bull. Pharmaceutical Society of Japan. 56 (1): ... protects osteoblasts against insults and promotes cell maturation". International Journal of Nanomedicine. Dovepress. 2011 (6 ...
*  Mir-25 microRNA precursor family
"Differences in osteoblast miRNA induced by cell binding domain of collagen and silicate-based synthetic bone". Journal of ... Regulates Osteoblast RNA Interfering". Journal of Prosthodontics. 17 (7): 522-526. doi:10.1111/j.1532-849X.2008.00331.x. PMID ...