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*  Endomorphin
The endomorphins are a group of endogenous opioid peptides consisting of endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin-2 ... Tyr-Pro-Phe-Phe-NH2). They are tetrapeptides with the highest known affinity and selectivity for the μ-opioid receptor. ...
*  Leumorphin
... similarly to other endogenous opioid peptide derivatives of prodynorphin. Opioid peptide Schwarzer C (September 2009). "30 ... Leumorphin, also known as dynorphin B1-29, is a naturally occurring endogenous opioid peptide. Derived as a proteolytic ... Leon F. Tseng (1 September 1995). Pharmacology of Opioid Peptides. CRC Press. p. 171. ISBN 978-3-7186-5632-5. Retrieved 22 ... December 1983). "Leumorphin is a novel endogenous opioid peptide derived from preproenkephalin B". Biochemical and Biophysical ...
*  DAMGO
... ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin) is a synthetic opioid peptide with high μ-opioid receptor specificity. It was ... "Reducing Tolerance To Morphine Could Aid Pain Therapy". A.K. Finn and J. Whistler (2001). "Endocytosis of the Mu Opioid ... He, Li; Fong, Jamie; von Zastrow, Mark; Whistler, Jennifer L (2002). "Regulation of Opioid Receptor Trafficking and Morphine ... synthesized as a biologically stable analog of δ-opioid receptor-preferring endogenous opioids, leu- and met-enkephalin. Its ...
*  Μ-opioid receptor
They are also referred to as μ-opioid peptide (MOP) receptors. The prototypical μ-opioid receptor agonist is morphine, the ... Perhaps, both might be involved in opioid addiction and opioid-induced deficits in cognition. Activation of the μ-opioid ... The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low ... Opioid overdoses can be rapidly reversed through the use of opioid antagonists, naloxone being the most widely used example. δ- ...
*  OGFr
The endogenous ligand is thus a known opioid peptide, and OGFr was originally discovered and named as a new opioid receptor ... Opioid growth factor receptor, also known as OGFr or the ζ-opioid receptor, is a protein which in humans is encoded by the OGFR ... Zagon IS, Donahue RN, McLaughlin PJ (2009). "Opioid growth factor-opioid growth factor receptor axis is a physiological ... "The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer". ...
*  Opioid peptide
Opioid peptides are peptides that bind to opioid receptors in the brain; opiates and opioids mimic the effect of these peptides ... Exorphins include opioid food peptides like Gluten exorphin and opioid food peptides and are mostly contained in cereals and ... The opioid food peptides have lengths of typically 4-8 amino acids. The body's own opioids are generally much longer. Opioid ... The effects of these peptides vary, but they all resemble those of opiates. Brain opioid peptide systems are known to play an ...
*  Opioid food peptides
... include: Casomorphin (from milk) Gluten exorphin (from gluten) Gliadorphin/gluteomorphin (from gluten) ...
*  Neuromodulation
Opioid peptides - a large family of endogenous neuropeptides that are widely distributed throughout the central and peripheral ... Froehlich, J. C. (1 January 1997). "Opioid peptides" (PDF). Alcohol Health and Research World. 21 (2): 132-136. ISSN 0090-838X ...
*  DPDPE
... ([D-Pen2,D-Pen5]enkephalin) is a synthetic opioid peptide and a selective agonist of the δ-opioid receptor (DOR) which is ... DADLE DAMGO L F Tseong (1 September 1995). Pharmacology of Opioid Peptides. CRC Press. pp. 9-. ISBN 978-3-7186-5632-5. Abba ... Kastin; Abba J. Kastin (28 April 2011). Handbook of Biologically Active Peptides. Academic Press. pp. 1430-. ISBN 978-0-08- ...
*  Quadazocine
Leon F. Tseng (1 September 1995). Pharmacology of Opioid Peptides. CRC Press. p. 238. ISBN 978-3-7186-5632-5. Retrieved 22 ... Gharagozlou P, Hashemi E, DeLorey TM, Clark JD, Lameh J (2006). "Pharmacological profiles of opioid ligands at kappa opioid ... "Multiple opioid receptor profile in vitro and activity in vivo of the potent opioid antagonist Win 44,441-3". Life Sciences. 33 ... It acts as a silent antagonist at all three of the major opioid receptors-μ, κ, and δ, but with a significant preference in ...
*  Phyllomedusa bicolor
Amiche M, Delfour A, Nicolas P (1998). "Opioid peptides from frog skin". EXS. 85: 57-71. doi:10.1007/978-3-0348-8837-0_4. PMID ... The skin secretion of the frog contains the opioid peptides deltorphin, deltorphin I, deltorphin II and dermorphin. The ... July 1989). "Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding ... Melchiorri P, Negri L (1996). "The dermorphin peptide family". General Pharmacology: The Vascular System. 27 (7): 1099-107. doi ...
*  Greek letters used in mathematics, science, and engineering
Opioid Peptides + 268 pp. Applied Linear Statistical Models (5th ed.). Michael H. Kutner, Christopher J. Nachtsheim, John Neter ...
*  Dermorphin
The peptide is a natural opioid that binds as an agonist with high potency and selectivity to mu Opioid receptors. Dermorphin ... Amiche M, Delfour A, Nicolas P (1998). "Opioid peptides from frog skin". EXS. 85: 57-71. doi:10.1007/978-3-0348-8837-0_4. PMID ... 1981). "Pharmacological data on dermorphins, a new class of potent opioid peptides from amphibian skin". Br. J. Pharmacol. 73 ( ... 1989). "Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding sites ...
*  Amidorphin
Opioid peptide Seizinger BR; Liebisch DC; Gramsch C; et al. (1985). "Isolation and structure of a novel C-terminally amidated ... Amidorphin is an endogenous, C-terminally amidated, opioid peptide generated as a cleavage product of proenkephalin A that is ... In some brain areas, amidorphin is extensively further reduced into smaller fragments, such as the non-opioid peptide ... Liebisch DC, Seizinger BR, Michael G, Herz A (November 1985). "Novel opioid peptide amidorphin: characterization and ...
*  Dynorphin
in their work with opioid peptides. The group discovered an endogenous opioid peptide in the porcine pituitary that proved ... the peptides do have some affinity for the μ-opioid receptor (MOR), δ-opioid receptor (DOR), and the N-methyl-D-aspartic acid ( ... an opioid peptide antagonist. Mandenoff et al. proposed that, although endogenous opioids are not necessary to maintain body ... applied the synthetic peptide to the guinea ileum longitudinal muscle and found it to be an extraordinarily potent opioid ...
*  Cytochrophin-4
... is an opioid peptide. Liebmann, C; Schrader, U; Brantl, V (1989). "Opioid receptor affinities of the blood- ...
*  Opioid excess theory
Hunter, L. C.; O'Hare, A.; Herron, W. J.; Fisher, L. A.; Jones, G. E. (2007). "Opioid peptides and dipeptidyl peptidase in ... speculated that food-derived peptides "may exert central-opioid effects, directly or through the formation of ligands with ... The opioid excess theory is a theory which postulates that autism is the result of a metabolic disorder in which opioid ... which in turn allows these opioid peptides to enter the brain. This hypothesis was first proposed by Jaak Panksepp in a 1979 ...
*  Signal transduction
Goldstein A (Sep 1976). "Opioid peptides endorphins in pituitary and brain". Science. 193 (4258): 1081-6. Bibcode:1976Sci... ... Produced mRNA needs to be translated, and the produced protein/peptide can undergo Posttranslational_modification (PMT)) ...
*  Hemorphin-4
Casomorphin Brantl V, Gramsch C, Lottspeich F, Mertz R, Jaeger KH, Herz A (June 1986). "Novel opioid peptides derived from ... Hemorphin-4 is an endogenous opioid peptide of the hemorphin family which possesses antinociceptive properties and is derived ... Hemorphin-4 has affinities for the μ-, δ-, and κ-opioid receptors that are in the same range as the structurally related β- ... Davis TP, Gillespie TJ, Porreca F (1989). "Peptide fragments derived from the beta-chain of hemoglobin (hemorphins) are ...
*  Hemorphin
Casomorphin Brantl V, Gramsch C, Lottspeich F, Mertz R, Jaeger KH, Herz A (June 1986). "Novel opioid peptides derived from ... Hemorphins are a class of naturally occurring, endogenous opioid peptides which are found in the bloodstream, and are derived ... They have antinociceptive effects via activation of the opioid receptors, and some may also play a role in blood pressure ... Davis TP, Gillespie TJ, Porreca F (1989). "Peptide fragments derived from the beta-chain of hemoglobin (hemorphins) are ...
*  Pain in crustaceans
... endogenous opioids are neurochemicals that moderate pain by interacting with opioid receptors. Opioid peptides and opioid ... In vertebrates, opioid peptides (i.e., enkephalins) have been shown to be involved in nociception. Leu-enkephalin and Met- ... Naloxone is an opioid-receptor antagonist and therefore blocks the effects of morphine. Opioid modulation of nociception has ... Crustaceans have a functional opioid system which includes the presence of opioid receptors similar to those of mammals. Delta ...
*  Difelikefalin
... is an analgesic opioid peptide acting as a peripherally specific, highly selective agonist of the κ-opioid receptor (KOR). It ... ISBN 978-1-139-49198-3. Janecka A, Perlikowska R, Gach K, Wyrebska A, Fichna J (2010). "Development of opioid peptide analogs ...
*  Pain in invertebrates
The involvement of opioid peptides in stress-induced analgesia in the slug Arion ater. Peptides:, 10:9-13 Kavaliers, M. and ... It has been found that molluscs and insects have opioid binding sites or opioid general sensitivity. Certainly there are many ... These latter functions might explain the presence of opioids and opioid receptors in extremely simple invertebrates and ... Role of opioid peptides in behavior of invertebrates. Journal of Evolutionary Biochemistry and Physiology, 37: 253-261 Pryor, S ...
*  Derek George Smyth
Smyth, D.G. (1983) Opioid Peptides and Pain. In: Clinics in Anaesthesiology, 1, 201-217. 43. Smyth, D.G. (1976) Searching for ... Derek Smyth is a British born scientist who specialises in peptide chemistry. Derek Smyth was Head of the Laboratory of Peptide ... Smyth, D.G. (1981) Chemistry of the opiate peptides: enkephalins and endorphins. In: Proceedings of the 6th European Peptide ... The TRH-like peptides in rabbit testis are different from the TRH-like peptide in the prostate. FEBS Letts., 379, 11-14. 56. ...
*  Enkephalinase
... s are enzymes that degrade endogenous enkephalin opioid peptides. They include: Aminopeptidase N (APN) Neutral ...
*  Adrenorphin
Opioid peptide Matsuo H, Miyata A, Mizuno K (1983). "Novel C-terminally amidated opioid peptide in human phaeochromocytoma ... Adrenorphin exhibits potent opioid activity, acting as a balanced μ- and κ-opioid receptor agonist while having no effects on δ ... Adrenorphin, also sometimes referred to as metorphamide, is an endogenous, C-terminally amidated, opioid octapeptide (Tyr-Gly- ... December 1983). "Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain ...
*  De novo peptide sequencing
Dass, Chhabil; Desiderio, Dominic M. (May 1987). "Fast atom bombardment mass spectrometry analysis of opioid peptides". ... For example, a precursor peptide with a molecular weight of 774 has 21,909,046 possible peptides. Even though it is done in the ... In mass spectrometry, de novo peptide sequencing is the method in which a peptide amino acid sequence is determined from tandem ... Three different types of backbone bonds can be broken to form peptide fragments: alkyl carbonyl (CHR-CO), peptide amide bond ( ...