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*  Oncolytic virus
... oncolytic virotherapy) prolongs survival in melanoma patients after surgical excision of the tumour in a retrospective study". ... The pool of resultant oncolytic viruses can then be further screened in pre-clinical models to select an oncolytic virus with ... "VEGF Blockade Enables Oncolytic Cancer Virotherapy in Part by Modulating Intratumoral Myeloid Cells". Molecular Therapy. 21 (5 ... has been shown to reduce the inflammatory response to oncolytic HSV and improve virotherapy in mice. In science fiction, the ...
*  Virotherapy
Oncolytic virotherapy is not a new idea - as early as the mid 1950s doctors were noticing that cancer patients who suffered a ... There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral ... oncolytic virotherapy) prolongs survival in melanoma patients after surgical excision of the tumour in a retrospective study". ... Virotherapy with Rigvir is successfully used in Latvia and by patients from more than 25 countries around the world. Recent ...
*  Andrew Pecora
Oncolytic Virotherapy. 6: 1-9. doi:10.2147/ov.s116012. Biography at John Theurer Cancer Center Testimony to the Congressional ... This false appearance of increase in cancer cells was confirmed by a later trial of the same oncolytic virus and also in Onyx ... July 2003). "Getting oncolytic virus therapies off the ground". Cancer Cell. 4 (1): 7-11. doi:10.1016/s1535-6108(03)00170-3. ... In the Phases 1 clinical trial, they found that intravenous administration of the oncolytic viruses led to inflammation of the ...
*  RIGVIR
"Oncolytic virotherapy including Rigvir and standard therapies in malignant melanoma". Oncolytic virotherapy. 6: 11-18. doi: ... In 1965, cancer virotherapy laboratory was founded in the Institute of Microbiology (Latvian Academy of Sciences) to explore ... RIGVIR (Riga virus) is a virotherapy medication approved by the State Agency of Medicines of the Republic of Latvia. There is ... List of unproven and disproven cancer treatments Oncolytic virus For a freely accessible English version see page 642 of ...
*  Senecavirus
Virotherapy Oncolytic virus "Viral Zone". ExPASy. Retrieved 15 June 2015. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 15 ... "Targeting pediatric cancer stem cells with oncolytic virotherapy". Pediatric Research. 71 (4-2): 500-510. doi:10.1038/pr. ... a Systemically Deliverable Oncolytic Picornavirus, and the Treatment of Neuroendocrine Cancers". JNCI Journal of the National ... a novel oncolytic picornavirus". Journal of General Virology. 89 (5): 1265-1275. doi:10.1099/vir.0.83570-0. PMID 18420805. ...
*  Measles virus encoding the human thyroidal sodium iodide symporter (MV-NIS)
Russell, Stephen J. "Oncolytic Virotherapy for Multiple Myeloma Oncolytic Virotherapy for Multiple Myeloma" (PDF). ... Virotherapy Oncolytic virus "Drug Dictionary". Compass Oncology. Retrieved 21 August 2014. Russell, Stephen J.; Mark J. ... Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy Active clinical trials for MV-NIS, National Cancer ... "Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy". Mayo Clinic Proceedings. 89 (7): 926-933. doi:10.1016/j ...
*  Genelux Corporation
"Genelux, a Leader in the Emerging Oncolytic Virotherapy Field, Receives Significant Industry Honor from Elsevier Business ... The main focus of Genelux is oncolytic immunotherapy based on attenuated, genetically engineered oncolytic viruses as ... "Bacterial glucuronidase as general marker for oncolytic virotherapy or other biological therapies". J Transl Med. 9: 172. doi: ... "Phase I clinical trial of a genetically modified and oncolytic vaccinia virus GL-ONC1 with green fluorescent protein imaging ...
*  Talimogene laherparepvec
Virotherapy Oncolytic adenovirus "Talimogene laherparepvec". AdisInsight. Retrieved 16 October 2016. Fukuhara, H; Ino, Y; Todo ... The first oncolytic virus to be approved by a regulatory agency was a genetically modified adenovirus named H101 by Shanghai ... It was the first oncolytic virus approved in the West; it was approved in the US in October 2015 and provisionally approved in ... It was the first approval of an oncolytic virus in the West. It was provisionally approved by the European Medicines Agency in ...
*  Reolysin
Virotherapy Oncolytic virus "What is Reolysin®? , Oncolytics Biotech Inc". Oncolytics Biotech Inc. Retrieved 2017-11-07. Lal, R ... E Karapanagiotou, H.S Pandha, G Hall, J Chester et al., Phase I/II trial of oncolytic reovirus (REOLYSIN) in combination with ... REOLYSIN is classified as an oncolytic virus, a virus that preferentially lyses cancer cells. Based on both single-arm and ... Nagano, S; Perentes, JY; Jain, RK; Boucher, Y (2008). "Cancer Cell Death Enhances the Penetration and Efficacy of Oncolytic ...
*  Oncolytic adenovirus
Oncolytic virus Oncolytic herpes virus Virotherapy Pandha, K. J. Harrington ; edited by Richard G. Vile, Hardev (2008). Viral ... Kirn D (2001). "Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015) results of phase I and II trials". ... For example, oncolytic vaccines based on the Ad5 serotype have relatively poor clinical efficacy as monotherapies. The need for ... Adenovirus varieties have been explored extensively as a viral vector for gene therapy and also as an oncolytic virus. Of the ...
*  Nick Lemoine
... "the genomics and molecular pathology of pancreatic cancer and the development of oncolytic virotherapy". He was educated at ...
*  Abscopal effect
Immunogenic Chemotherapy or IFN-α Blockade Boost the Local and Abscopal Effects of Oncolytic Virotherapy. Cancer Res. 2017;77: ...
*  Oncolytic herpes virus
Clinical trials Including phase III : See Talimogene laherparepvec Virotherapy Oncolytic virus Oncolytic adenovirus Herpes ... Varghese, S; Rabkin, SD (2002). "Oncolytic herpes simplex virus vectors for cancer virotherapy". Cancer gene therapy. 9 (12): ... "Oncolytic herpes simplex virus vectors for cancer virotherapy". Cancer Gene Therapy. 9 (12): 967-78. doi:10.1038/sj.cgt.7700537 ... "Response to Intra-Arterial Oncolytic Virotherapy with the Herpes Virus NV1020 Evaluated by [18F]Fluorodeoxyglucose Positron ...
*  Poliovirus
"Oncolytic polio virotherapy of cancer". Cancer. 120 (21): 3277-3286. doi:10.1002/cncr.28862. PMC 4205207 . PMID 24939611. ...
*  PVSRIPO
"Oncolytic polio virotherapy of cancer". Cancer. 120 (21): 3277-3286. doi:10.1002/cncr.28862. PMC 4205207 . PMID 24939611. ... Oncolytic virus Brown, Michael C.; Dobrikova, Elena Y.; Dobrikov, Mikhail I.; Walton, Ross W.; Gemberling, Sarah L.; Nair, ... Oncolytic Poliovirus Receives Breakthrough Designation for Glioblastoma. May 2016 "Targeting Cancer with Genetically Engineered ...
*  Viralytics
Virotherapy Oncolytic virus "Psiron's Cavatak received Orphan Drug Designation from the FDA" (PDF). asx.com.au. 21 December ... The company's oncolytic virus product, called Cavatak, is currently in clinical trials in metastatic melanoma and other cancers ... Psiron changed its name in the process to Viralytics to reflect the fact that oncolytic viruses were now its core focus. ... Au GG, Lincz LF, Enno A, Shafren DR (2007). "Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma". Br J ...
*  CGTG-102
The therapeutic potential of oncolytic virotherapy is not a simple consequence of the cytopathic effect but strongly relies on ... "Oncolytic viruses mediating anti-tumor immunity in human cancer patients" (Press release). Oncos Therapeutics. 19 May 2010. s.r ... While the CGTG-102 oncolytic adenovirus has shown efficacy as a single agent against several soft tissue sarcomas, it would ... CGTG-102 (Ad5/3-D24-GMCSF), (developed by Oncos Therapeutics) is an oncolytic adenovirus currently in orphan drug status for ...
*  Epithelioid sarcoma
It has been noted that the therapeutic potential of oncolytic virotherapy is not a simple consequence of the cytopathic effect ... While the CGTG-102 oncolytic adenovirus has shown efficacy as a single agent against several soft tissue sarcomas, it would ... Superior anticancer effects have been observed when oncolytic viruses are engineered to express (or be co-administered with) ... Hemminki, Akseli (2014). "Oncolytic Immunotherapy: Where Are We Clinically?". Scientifica. 2014: 862925. doi:10.1155/2014/ ...
*  Herpes simplex virus
Varghese S, Rabkin SD (1 December 2002). "Oncolytic herpes simplex virus vectors for cancer virotherapy". Cancer Gene Therapy. ... virus is considered as a potential therapy for cancer and has been extensively clinically tested to assess its oncolytic ( ...
*  List of unproven and disproven cancer treatments
It may also cause potentially serious side effects." RIGVIR - a virotherapy medication approved by the State Agency of ... "Oncolytic enteroviruses" (PDF). Molecular Biology. 46 (5): 639-50. doi:10.1134/S0026893312050032. For the original version in ... "Ty Bollinger's "The Truth About Cancer" and the unethical marketing of the unproven cancer virotherapy Rigvir". Retrieved 19 ... Russian see Chumakov PM, Morozova VV, Babkin IV, Baĭkov IK, Netesov SV, Tikunova NV (2012). "[Oncolytic enteroviruses] (Russian ...
*  Virus
In similar fashion, virotherapy uses viruses as vectors to treat various diseases, as they can specifically target cells and ... Viruses that have been reprogrammed to kill cancer cells are called oncolytic viruses. Current trends in nanotechnology promise ... Virotherapy involves the use of genetically modified viruses to treat diseases. Viruses have been modified by scientists to ... Burke, J; Nieva, J; Borad, M. J.; Breitbach, C. J. (2015). "Oncolytic viruses: Perspectives on clinical development". Current ...
*  Newcastle disease
Though the oncolytic effect of NDV was documented already in the 1950s, the main advances of viruses in cancer therapy came ... NDV possesses many unique anticancer properties and thereby provides an excellent base in virotherapy research. NDV has ... 1 March 2006 "Oncolytic Specificity of Newcastle Disease Virus Is Mediated by Selectivity for Apoptosis-Resistant Cells". ... Altomonte, J; Marozin, S; Schmid, RM; Ebert, O (Feb 2010). "Engineered newcastle disease virus as an improved oncolytic agent ...
*  Timeline of cancer treatment development
Oncolytic viruses began human clinical trials 1951 - Dr. Jane C. Wright demonstrated the use of the antifolate, methotrexate in ... oncological virotherapy 1966 - Taxol, anti-cancer compound, isolated from the yew plant 1967 - Camptothecin, anti-cancer ... ". "Clinical virotherapy: four historically significant clinical trials". Huebner, RJ; Rowe, WP; Schatten, WE; Smith, RR; ...
*  Hussein Naim
Oncolytic measles virus in cutaneous T-cell lymphomas mount anti-tumor immune responses in vivo and target interferon resistant ... live recombinant vaccines and cancer virotherapy). Later, he became the director of vaccine research at Berna Biotech (now ...
*  Index of oncology articles
... oncolytic - Oncolytic virus - Onconase - ondansetron - ONYX-015 - oophorectomy - open biopsy - open colectomy - open label ... virotherapy - virtual colonoscopy - Virulizin - virus replication cycle - virus-neutralizing antibody - viscotoxin - ...
*  Circulating tumor cell
Oncolytic viruses such as vaccinia viruses are developed to detect and identify CTCs. Physical methods are often filter-based, ... "Optical Detection and Virotherapy of Live Metastatic Tumor Cells in Body Fluids with Vaccinia Strains". PLoS ONE. 8 (9): e71105 ...