"Oncolytic virotherapy including Rigvir and standard therapies in malignant melanoma". Oncolytic Virotherapy. 6: 11-18. doi: ... has been shown to reduce the inflammatory response to oncolytic HSV and improve virotherapy in mice. A modified oncolytic ... Turnbull S, West EJ, Scott KJ, Appleton E, Melcher A, Ralph C (December 2015). "Evidence for Oncolytic Virotherapy: Where Have ... Conry RM, Westbrook B, McKee S, Norwood TG (February 2018). "Talimogene laherparepvec: First in class oncolytic virotherapy". ...
Saga K, Kaneda Y (2015). "Oncolytic Sendai virus-based virotherapy for cancer: recent advances". Oncolytic Virotherapy. 4: 141- ... "Directed evolution as a tool for the selection of oncolytic RNA viruses with desired phenotypes". Oncolytic Virotherapy. 8: 9- ... "Directed evolution as a tool for the selection of oncolytic RNA viruses with desired phenotypes". Oncolytic Virotherapy. 8: 9- ... "Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer". Cancer Research. ...
"Oncolytic virotherapy including Rigvir and standard therapies in malignant melanoma". Oncolytic Virotherapy. 6: 11-18. doi: ... It was formerly approved as a virotherapy medication by the State Agency of Medicines of the Republic of Latvia (2004-19). In ... She was an honorary member of the Latvian Association of Oncologists and the founder of The Aina Muceniece Virotherapy ... Aina Muceniece". Virotherapy Foundation. Retrieved 19 September 2020. "Feasibility study for registration of medicine RIGVIR ...
"Oncolytic virotherapy including Rigvir and standard therapies in malignant melanoma". Oncolytic Virotherapy. Dovepress, New ... Double-stranded RNA viruses Oncolytic virus Orphan virus "Viral Zone". ExPASy. Retrieved 15 June 2015. Guglielmi, KM; Johnson, ... Thirukkumaran C, Morris DG (2009). "Oncolytic Viral Therapy Using Reovirus". Gene Therapy of Cancer. Methods in Molecular ... Reoviruses have been demonstrated to have oncolytic (cancer-killing) properties, encouraging the development of reovirus-based ...
Oncolytic Virotherapy. 6: 1-9. doi:10.2147/ov.s116012. PMC 5189707. PMID 28053943. Biography at John Theurer Cancer Center ... This false appearance of increase in cancer cells was confirmed by a later trial of the same oncolytic virus, and also in Onyx ... July 2003). "Getting oncolytic virus therapies off the ground". Cancer Cell. 4 (1): 7-11. doi:10.1016/s1535-6108(03)00170-3. ... In the phase 1 clinical trial, they found that intravenous administration of the oncolytic viruses led to inflammation of the ...
"Oncolytic virotherapy including Rigvir and standard therapies in malignant melanoma". Oncolytic Virotherapy. 6: 11-18. doi: ... Engeland, Christine; Bell, John (2020). "Introduction to Oncolytic Virotherapy". Oncolytic Viruses. Methods Mol Biol. Vol. 2058 ... Oncolytic virotherapy is not a new idea - as early as the mid 1950s doctors were noticing that cancer patients who suffered a ... It was the first oncolytic virus approved in the West. RIGVIR is a virotherapy drug that was approved by the State Agency of ...
Virotherapy Oncolytic virus , type = Public company , traded_as = ASX: VLA "Psiron's Cavatak received Orphan Drug Designation ... The company's oncolytic virus product, called Cavatak, is currently in clinical trials in metastatic melanoma and other cancers ... Psiron changed its name in the process to Viralytics to reflect the fact that oncolytic viruses were now its core focus. ... Au GG, Lincz LF, Enno A, Shafren DR (2007). "Oncolytic Coxsackievirus A21 as a novel therapy for multiple myeloma". Br J ...
Virotherapy Oncolytic virus "Viral Zone". ExPASy. Retrieved 15 June 2015. "Virus Taxonomy: 2020 Release". International ... "Targeting pediatric cancer stem cells with oncolytic virotherapy". Pediatric Research. 71 (4-2): 500-510. doi:10.1038/pr. ... There is only one species in this genus: Senecavirus A. Senecavirus is a replication-competent oncolytic picornavirus. It has ... a Systemically Deliverable Oncolytic Picornavirus, and the Treatment of Neuroendocrine Cancers". JNCI Journal of the National ...
November 2014). "Oncolytic polio virotherapy of cancer". Cancer. 120 (21): 3277-86. doi:10.1002/cncr.28862. PMC 4205207. PMID ...
"Oncolytic polio virotherapy of cancer". Cancer. 120 (21): 3277-3286. doi:10.1002/cncr.28862. PMC 4205207. PMID 24939611. " ... Oncolytic virus Brown, Michael C.; Dobrikova, Elena Y.; Dobrikov, Mikhail I.; Walton, Ross W.; Gemberling, Sarah L.; Nair, ... "Oncolytic Poliovirus Receives Breakthrough Designation for Glioblastoma". May 2016. Archived from the original on 2016-05-20. ... Virotherapy, Biotechnology, Emerging technologies, Experimental drugs, Infraspecific virus taxa). ...
Russell, Stephen J. "Oncolytic Virotherapy for Multiple Myeloma Oncolytic Virotherapy for Multiple Myeloma" (PDF). ... Virotherapy Oncolytic virus "Drug Dictionary". Compass Oncology. Retrieved 21 August 2014. Russell, Stephen J.; Mark J. ... Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy Active clinical trials for MV-NIS, National Cancer ... "Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy". Mayo Clinic Proceedings. 89 (7): 926-933. doi:10.1016/j ...
"Optimizing oncolytic virotherapy in cancer treatment". Nature Reviews Drug Discovery. 18 (9): 689-706. doi:10.1038/s41573-019- ... Lawler, Sean E.; Speranza, Maria-Carmela; Cho, Choi-Fong; Chiocca, E. Antonio (1 June 2017). "Oncolytic Viruses in Cancer ... Virotherapy Antibodies[additional citation(s) needed] Photoimmunotherapy (for brain cancer)[additional citation(s) needed] ...
In some countries oncolytic virotherapy methods are studied and used to treat melanoma. Oncolytic virotherapy is a promising ... "Exploiting tumor epigenetics to improve oncolytic virotherapy". Frontiers in Genetics. 4: 184. doi:10.3389/fgene.2013.00184. ... branch of virotherapy, where oncolytic viruses are used to treat diseases; viruses can increase metabolism, reduce anti-tumor ... Talimogene laherparepvec (T-VEC) (which is a herpes simplex virus type 1-derived oncolytic immunotherapy), was shown to be ...
First in class oncolytic virotherapy". Hum Vaccin Immunother. 14 (4): 839-846. doi:10.1080/21645515.2017.1412896. PMC 5893211. ... Agarwalla PK, Aghi MK (2012). "Oncolytic Herpes Simplex Virus Engineering and Preparation". Oncolytic Viruses. Methods in ... The first oncolytic virus to be approved by a regulatory agency was a genetically modified adenovirus named H101 by Shanghai ... It was the first approval of an oncolytic virus and the first approval of a gene therapy in the West. It was approved by the ...
Clinical trials Including phase III : See Talimogene laherparepvec Virotherapy Oncolytic virus Oncolytic adenovirus Herpes ... "Oncolytic herpes simplex virus vectors for cancer virotherapy". Cancer Gene Therapy. 9 (12): 967-78. doi:10.1038/sj.cgt.7700537 ... "Response to intra-arterial oncolytic virotherapy with the herpes virus NV1020 evaluated by [18F]fluorodeoxyglucose positron ... Like other oncolytic versions of HSV it has a deletion of the gene encoding ICP34.5, which provides tumor selectivity. It also ...
"Oncolytic Measles Virotherapy and Opposition to Measles Vaccination". Mayo Clinic Proceedings. 94 (9): 1834-39. doi:10.1016/j. ...
Varghese S, Rabkin SD (1 December 2002). "Oncolytic herpes simplex virus vectors for cancer virotherapy". Cancer Gene Therapy. ... virus is considered as a potential therapy for cancer and has been extensively clinically tested to assess its oncolytic ( ...
Virotherapy, Oncolytic virus). ... The oncolytic virus specifically infects and kills tumor cells ... Clinical trial number NCT00794131 for "Safety Study of GL-ONC1, an Oncolytic Virus, in Patients With Advanced Solid Tumors" at ... Tong AW, Senzer N, Cerullo V, Templeton NS, Hemminki A, Nemunaitis J (July 2012). "Oncolytic viruses for induction of anti- ... May 2015). "Phase I study of intra-pleural administration of GL-ONC1, an oncolytic vaccinia virus, in patients with malignant ...
Oncolytic virus Oncolytic AAV Oncolytic herpes virus Virotherapy Pandha, K. J. Harrington; edited by Richard G. Vile, Hardev ( ... Kirn D (2001). "Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015) results of phase I and II trials". ... Doronin, Konstantin; Shayakhmetov, Dmitry M. (2012). "Construction of Targeted and Armed Oncolytic Adenoviruses". Oncolytic ... For example, oncolytic vaccines based on the Ad5 serotype have relatively poor clinical efficacy as monotherapies. The need for ...
Oncolytic virotherapy is an emerging novel treatment that is under investigation both at preclinical and clinical stages. ... Suryawanshi YR, Schulze AJ (July 2021). "Oncolytic Viruses for Malignant Glioma: On the Verge of Success?". Viruses. 13 (7): ...
... "the genomics and molecular pathology of pancreatic cancer and the development of oncolytic virotherapy". He was educated at ...
Immunogenic Chemotherapy or IFN-α Blockade Boost the Local and Abscopal Effects of Oncolytic Virotherapy. Cancer Res. 2017;77: ...
... oncolytic virotherapy, gene therapy and immunotherapy. The latest research is reported annually at scientific meetings such as ... Suryawanshi YR, Zhang T, Essani K (March 2017). "Oncolytic viruses: emerging options for the treatment of breast cancer". ...
The therapeutic potential of oncolytic virotherapy is not a simple consequence of the cytopathic effect but strongly relies on ... "Oncolytic viruses mediating anti-tumor immunity in human cancer patients" (Press release). Oncos Therapeutics. 19 May 2010. ... While the ONCOS-102 oncolytic adenovirus has shown efficacy as a single agent against several soft tissue sarcomas, it would ... ONCOS-102 (Ad5/3-D24-GMCSF), (developed by Oncos Therapeutics) is an oncolytic adenovirus previously described as CGTG-102. It ...
Virotherapy, Oncolytic virus). ... oncolytic vaccinia virus, modified to increase its safety, ... Genelux Corporation is a late clinical-stage public company (Nasdaq: GNLX) developing a pipeline of next-generation oncolytic ... the companies announced the issuance of a United States patent covering the combination of an adoptive T cell therapy/oncolytic ... platform from which the Company has developed an extensive library of isolated and engineered oncolytic vaccinia virus ...
Mesenchymal Stem Cells Used as Carrier Cells of Oncolytic Adenovirus Results in Enhanced Oncolytic Virotherapy, Nature Sci Rep ...
It has been noted that the therapeutic potential of oncolytic virotherapy is not a simple consequence of the cytopathic effect ... While the CGTG-102 oncolytic adenovirus has shown efficacy as a single agent against several soft tissue sarcomas, it would ... Hemminki, Akseli (2014). "Oncolytic Immunotherapy: Where Are We Clinically?". Scientifica. 2014: 1-7. doi:10.1155/2014/862925. ... Superior anticancer effects have been observed when oncolytic viruses are engineered to express (or be co-administered with) ...
The company's product pipeline includes multiple immunotherapy B-cell vaccine candidates and an oncolytic virotherapy (CF33) ... CF33-CD19 oncolytic virus was then combined with CD19 CAR T cells in vitro and in vivo mice studies. Researchers showed ... Researchers first created an oncolytic virus (CF33-CD19) in the lab of City of Hope's Professor Yuman Fong, M.D., to get into ... onCARlytics (CF33-CD19) is a novel immunotherapy utilising the CF33 oncolytic virus to deliver and present CD19 antigen on the ...
Research and Reviews Nutrition and Dietary Supplements Oncolytic Virotherapy OncoTargets and Therapy Open Access Animal ...
... as an oncolytic virotherapy, commercialized by Amgen Inc. This oncolytic herpes virus, named Talimogene laherparepvec, has been ...