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*  Okadaic acid
However, the unique function of okadaic acid upon cells maintained biological interest in the molecule. Okadaic acid has been ... okadaic acid has shown promise in the world of medicine for numerous potential uses. During its initial discovery, okadaic acid ... was compared to and shown to be very chemically similar to okadaic acid several years later, and okadaic acid itself was ... several studies have been performed toward the synthesis of okadaic acid and its derivatives. 3 total syntheses of okadaic acid ...
*  Dinophysis acuta
The main chemical toxins were identified in 2006 as okadaic acid and pectenotoxins. They can produce non-fatal or fatal amounts ... In 2004, the presence of okadaic acid esters was reported. Further identification and the importance of these compounds as ... Suzuki, T.; Beuzenberg, V.; Mackenzie, L.; Quilliam, M. A. (2004). "Discovery of okadaic acid esters in the toxic ... "Isolation and identification of a cis-C8-diol-ester of okadaic acid from Dinophysis acuta in New Zealand". Toxicon. 48 (2): 195 ...
*  Diarrhetic shellfish poisoning
The causative poison is okadaic acid, which inhibits intestinal cellular de-phosphorylation. This causes the cells to become ...
*  LUC7L3
Chin LS, Singh SK, Wang Q, Murray SF (2000). "Identification of okadaic-acid-induced genes by mRNA differential display in ... Nucleic Acids Res. 35 (17): 5874-85. doi:10.1093/nar/gkm505. PMC 2034479 . PMID 17726058. ...
*  GIMAP5
2004). "Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis". Mol. Biol. Cell. 14 (8): 3292-304. doi ... Nucleic Acids Res. 29 (6): 1308-16. doi:10.1093/nar/29.6.1308. PMC 29751 . PMID 11238997. Stamm O, Krücken J, Schmitt-Wrede HP ...
*  EIF1
Chin LS, Singh SK, Wang Q, Murray SF (2000). "Identification of okadaic-acid-induced genes by mRNA differential display in ...
*  GNMT
Møller MT, Samari HR, Fengsrud M, Strømhaug PE, øStvold AC, Seglen PO (July 2003). "Okadaic acid-induced, naringin-sensitive ... at the amino acid level. All GNMTs are 130 kDa tetramers consisting of four identical subunits, each having a Mr of 32 kDa. The ...
*  Fish as food
... okadaic acid, saxitoxins, ciguatoxin and domoic acid. Except for ciguatoxine, high levels of these toxins are only found in ... Both domoic acid and ciguatoxine can be deadly to humans; the others will only cause diarrhea, dizzyness and a (temporary) ... Fish, like anchovies can also concentrate toxins such as domoic acid. If suspected, medical attention should be sought. The ... Kris-Etherton, Penny M.; William S. Harris; Lawrence J. Appel (2002). "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and ...
*  Suberites
FEMS Microbiology Ecology 85, 465 (2013). H. C. Schröder et al., Okadaic Acid, an Apoptogenic Toxin for Symbiotic/Parasitic ... Symbiotic bacteria produce toxins, such as okadaic acid, which defend them from colonization by parasitic annelids. Expression ...
*  Ceramide-activated protein phosphatase
Okadaic acid is a complex fatty acid polyether and a potent CAPP inhibitor (Hannun, 1996). Okadaic acid is mainly used as a ... Okadaic acid is commonly used for producing cellular models without CAPP activity (Hannun, 1996). I2PP2A does not inhibit CAPP ... CAPP was first linked to carcinogenesis when it was noticed that okadaic acid acted as a tumor promoter and it was postulated ... Treatment of neuronal cells with okadaic acid has been shown to cause tau neurofibrillary tangles, indicating that disruptions ...
*  Dinophysis
Attention to Dinophysis greatly increased as several species of the genus were linked to the toxin including okadaic acid ... "Does the marine biotoxin okadaic acid cause DNA fragmentation in the blue mussel and the pacific oyster?". Marine Environmental ...
*  Oxaziridine
System of Okadaic acid. Epoxidation of alkenes is a common reaction because epoxides can be derivatized in a number of useful ... System of Okadaic Acid". Org. Lett. 1 (3): 451. doi:10.1021/ol9906615. Malgesini, Beatrice; Forte, Barbara; Borghi, Daniela; ... Oxaziridines have been found to be useful for the formation of highly acid sensitive epoxides. (−)-Chaetominine was synthesized ... A general approach to the synthesis of enantiomerically pure .alpha.-hydroxy carboxylic acid synthons". journal of the American ...
*  Lubomirskia baicalensis
Okadaic acid produced by the dinoflagellate assists the sponge to survive when Lake Baikal is iced over in winter, and the ... Role of okadaic acid produced by symbiotic dinoflagellates". FEBS J. National Center for Biotechnology Information. 274 (1): 23 ...
*  Brevetoxin
Algal bloom Red tide Ciguatoxin Domoic acid Okadaic acid Saxitoxin Tetrodotoxin Watkins SM, Reich A, Fleming LE, Hammond R ( ... Attention was turned to the citric acid cycle to solve the problem. Acetate can be used in the polyketide synthetic pathway or ... Previous studies of the citric acid pathway revealed three and four carbon units that can potentially explain the atypical ... modified by the citric acid cycle. Intermediate products of this cycle can then be reintroduced to the polyketide synthetic ...
*  Protein phosphatase 1
Potential inhibitors include a variety of naturally occurring toxins including okadaic acid, a diarrhetic shellfish poison, ... These metal ions have been identified as Mn and Fe and their coordination is provided by three histidines, two aspartic acids, ...
*  Yessotoxin
... toxins along the lines of okadaic acid and azaspiracids. These type of toxins can cause extreme gastrointestinal upset and ... The original Yasumoto MBA is subject to interferences from paralytic shellfish toxins and free fatty acids in solution, which ... is the official reference method used to analyse for YTX and lipophilic toxins including okadiac acid, dinophysistoxins (DSPs ...
*  C-Fos
"Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced ... Lee SK, Kim JH, Lee YC, Cheong J, Lee JW (April 2000). "Silencing mediator of retinoic acid and thyroid hormone receptors, as a ... c-fos is a 380 amino acid protein with a basic leucine zipper region for dimerisation and DNA-binding and a transactivation ... Nichols CD, Sanders-Bush E (May 2002). "A single dose of lysergic acid diethylamide influences gene expression patterns within ...
*  Dinophysis acuminata
... as they produce okadaic acid which can cause diarrhetic shellfish poisoning (DSP). Okadiac acid is taken up by shellfish and ...
*  Fibropapillomatosis
First, the toxic compound lyngbyatoxin from the cyanobacterium Lyngbya majuscule, and second the toxin okadaic acid - a ...
*  Toxin
Mouratidou, Theoni; Kaniou-Grigoriadou, I.; Samara, C.; Kouimtzis, T. (2006). "Detection of the marine toxin okadaic acid in ...
*  PTPRU
PCP-2 mRNA is regulated by phorbol myristate acetate (PMA) or calcium ionophore, okadaic acid, the Ras inhibitor manumycin, and ...
*  PHLPP
... okadaic acid]. PHLPP1 and PHLPP2 have a similar domain structure, which includes a putative Ras association domain, a ...
*  Canadian Reference Materials
... mussel tissue for okadaic acid OA, okadaic acid standard DTX, dinophysistoxin standards GYM, gymnodimine standards YTX and hYTX ... Amnesic shellfish poisoning toxins ASP-Mus-d, mussel tissue for domoic acid and its isomers DA-f, domoic acid standard ...
*  Ciguatoxin
Brevetoxin Domoic acid Okadaic acid Saxitoxin Tetrodotoxin Vetter I, Touska F, Hess A, Hinsbey R, Sattler S, Lampert A, ...
*  Tetrodotoxin
... under the effect of the drug 4-Aminopyridine Conotoxin Neurotoxin Neosaxitoxin Brevetoxin Ciguatoxin Domoic acid Okadaic acid ...
*  Domoic acid
Canadian Reference Materials Pseudo-nitzschia Quisqualic acid Brevetoxin Ciguatoxin Okadaic acid Saxitoxin Maitotoxin Clayden, ... "Chemistry of domoic acid, isodomoic acids, and their analogues" (PDF). Retrieved 2 April 2015. "Domoic Acid Toxicity". The ... Domoic acid (DA) is a kainic acid analog neurotoxin that causes amnesic shellfish poisoning (ASP). It is produced by algae and ... In addition domoic acid was used to poison a witness in the Elementary episode "The Red Team". Domoic acid overtakes Camp ...