Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA- ... Octamer+transcription+factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ... Zhao, FQ (1 June 2013). "Octamer-binding transcription factors: genomics and functions". Frontiers in Bioscience (Landmark ... "Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors ...
Okamoto K, Okazawa H, Okuda A, Sakai M, Murmatsu M, Hamada H (1990). "A novel octamer binding transcription factor is ... three of the four Yamanaka factors - Oct4, Sox2, KLF4, c-Myc) works together with other transcription factors to change the ... Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K (2017). "Cooperative Binding of Transcription Factors ... DNA methylation can modulate the binding affinities of transcription factors by recruiting repressors such as MeCP2 which ...
"Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription ... "A B-cell coactivator of octamer-binding transcription factors". Nature. 373 (6512): 360-2. Bibcode:1995Natur.373..360G. doi: ... BOB1 is a transcriptional coactivator (i.e. a protein that controls the activity of transcription factors) which is expressed ... POU domain POU domain class 2 transcription factors: POU2F1, POU2F2, POU2F3 GRCh38: Ensembl release 89: ENSG00000110777 - ...
... transcription factor 2 is a protein that in humans is encoded by the POU2F2 gene. Oct-2 is an octamer transcription factor ... Octamer+Transcription+Factor-2 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) FactorBook POU2F2 v t e ... Latchman DS (October 1996). "The Oct-2 transcription factor". The International Journal of Biochemistry & Cell Biology. 28 (10 ... Oct-2 (octamer-binding protein 2) also known as POU domain, class 2, ...
Sp1 transcription factor, and TATA binding protein. Octamer transcription factor GRCh38: Ensembl release 89: ENSG00000143190 - ... assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". J. Biol. Chem. ... "Recruitment of octamer transcription factors to DNA by glucocorticoid receptor". Mol. Cell. Biol. 18 (6): 3416-30. doi:10.1128/ ... "Recruitment of Octamer Transcription Factors to DNA by Glucocorticoid Receptor". Mol. Cell. Biol. 18 (6): 3416-30. doi:10.1128/ ...
"Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the ... The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcription factors. ... "Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR ... "Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR ...
Octamer transcription factor GRCh38: Ensembl release 89: ENSG00000184486 - Ensembl, May 2017 "Human PubMed Reference:". ... a nervous-system specific POU domain transcription factor binding to the octamer DNA motif". Nucleic Acids Research. 21 (2): ... which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and ... Goodall J, Wellbrock C, Dexter TJ, Roberts K, Marais R, Goding CR (April 2004). "The Brn-2 transcription factor links activated ...
B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors". ... Roeder RG, Engelke DR, Luse DS, Segall J, Shastry BS, Weil PA (1979). "Factors involved in the transcription of purified genes ... Segall J, Matsui T, Roeder RG (Dec 1980). "Multiple factors are required for the accurate transcription of purified genes by ... Engelke DR, Ng SY, Shastry BS, Roeder RG (Mar 1980). "Specific interaction of a purified transcription factor with an internal ...
Octamer-binding transcription factor 4, OCT-4, is a transcription factor protein that is encoded by the POU5F1 gene and is part ... Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a ... assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors". The Journal of ... Oct-4 transcription factor is initially active as a maternal factor in the oocyte and remains active in embryos throughout the ...
The original set of reprogramming factors (also dubbed Yamanaka factors) are the transcription factors Oct4 (Pou5f1), Sox2, ... genomic integration of the transcription factors limits the utility of the transcription factor approach because of the risk of ... each of the factors can be functionally replaced by related transcription factors, miRNAs, small molecules, or even non-related ... collectively known as Yamanaka factors, encoding transcription factors could convert somatic cells into pluripotent stem cells ...
... transcription factor 1 (also known as Oct-6) is a protein that in humans is encoded by the POU3F1 gene. Octamer transcription ... "High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors". The EMBO Journal. ... Tobler A, Schreiber E, Fontana A (Feb 1993). "The human Oct-6 POU transcription factor lacks the first 50 amino acids of its ... Suzuki N, Rohdewohld H, Neuman T, Gruss P, Schöler HR (Nov 1990). "Oct-6: a POU transcription factor expressed in embryonal ...
In mouse ESCs, Sall4 was found to bind the essential stem cell factor, octamer-binding transcription factor 4 (Oct4), in two ... "Stemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse ... Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL ... a stem cell transcription factor". Cell Cycle. 13 (9): 1456-1462. doi:10.4161/cc.28418. PMC 4050143. PMID 24626181. Gao C, ...
... may refer to two genes: Oct-4, octamer-binding transcription factor 4, also known as Oct-3 or OCT3 SLC22A3, solute carrier ... for organic cation transporter 3 This disambiguation page lists articles associated with the same title formed as a letter- ...
... the Pituitary-specific Pit-1 the Octamer transcription factor proteins Oct-1 and Oct-2 (octamer sequence is ATGCAAAT) the ... "Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors ... Mathis JM, Simmons DM, He X, Swanson LW, Rosenfeld MG (Jul 1992). "Brain 4: a novel mammalian POU domain transcription factor ... POU proteins are eukaryotic transcription factors containing a bipartite DNA binding domain referred to as the POU domain. The ...
"High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors". The EMBO Journal. ... "Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular ... Transcription factors, All stub articles, Human chromosome 4 gene stubs). ... 517 (1-3): 167-71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430. S2CID 84792445. Fan Z, Beresford PJ, Zhang D, Xu Z, Novina ...
This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an ... octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by ... "Entrez Gene: POU class 3 homeobox 3". Retrieved 2018-08-13. Li W, Zheng J, Deng J, You Y, Wu H, Li N, Lu J, Zhou Y (June 2014 ... POU class 3 homeobox 3 is a protein that in humans is encoded by the POU3F3 gene. ...
The GCM motif has been shown to be a DNA binding domain that recognises preferentially the nonpalindromic octamer 5'-ATGCGGGT-3 ... In molecular biology, the GCM transcription factors are a family of proteins which contain a GCM motif. The GCM motif is a ... Schreiber J, Sock E, Wegner M (April 1997). "The regulator of early gliogenesis glial cells missing is a transcription factor ... In GCM transcription factors the N-terminal moiety contains a DNA-binding domain of 150 amino acids. Sequence conservation is ...
"Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a ... NCOR2/SMRT serves as a repressive coregulatory factor (corepressor) for multiple transcription factor pathways. In this regard ... facilitating the recruitment of histone deacetylases to the DNA promoters bound by its interacting transcription factors. It is ... "Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including ...
In Drosophila, NURF interacts with the transcription factor GAGA to remodel chromatin at the hsp70 promoter, and null mutations ... NURF catalyzes nucleosome sliding in either direction on DNA without any apparent modifications to the histone octamer itself. ... NURF interacts with chromatin by binding to modified histones or interacting with various transcription factors. ... Nucleosome Remodeling Factor (NURF) is an ATP-dependent chromatin remodeling complex first discovered in Drosophila ...
Ben-Shushan E, Thompson JR, Gudas LJ, Bergman Y (April 1998). "Rex-1, a gene encoding a transcription factor expressed in the ... Rex1 participates in a network of transcription factors that all work to regulate each other via varying expression levels. The ... Rex1 was also found to inhibit NOTCH and STAT3, two transcription factors which lead to differentiation. Therefore, Rex1 ... April 2005). "Human bone marrow mesenchymal stem cells can express insulin and key transcription factors of the endocrine ...
1.65 turns around histone protein octamers. DNA within nucleosomes is inaccessible to many transcription factors. Some ... Plant transcription factor database TcoF-DB: Database of transcription co-factors and transcription factor interactions ... This is also true with transcription factors: Not only do transcription factors control the rates of transcription to regulate ... an important class of transcription factors called general transcription factors (GTFs) are necessary for transcription to ...
Pituitary-specific positive transcription factor 1, Pou1f1), Oct1 (Pou2f1), and the Caenorhabditis elegans factor Unc86, and ... and endocrine systems that functions on elements distinct from known octamer motifs". Proceedings of the National Academy of ... interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription". Cancer Biology & ... interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription". Cancer Biology & ...
Transcriptions factors have different binding sites for its development, some examples are: GATA, activator protein 1 and 2 (AP ... and AP-2), and numerous potential Octamer-1 binding sites. A Glycogenin-1 deficiency leads to Glycogen storage disease type XV ... There are also nine E-boxes that bind the basic helix-loop-helix of muscle-specific transcription factors. The GYG1 gene is ... Transcription of human glycogenin-1 is mainly initiated at 80bp and 86bp upstream the translator's codon beginning. ...
Many SOX/SRY-sex/testis determining and related HMG box factor transcription factors and estrogen related transcription factors ... The H2A proteins specifically play a role in the octamer structure of histone. ERICH2 is specifically known to interact with ... This protein functions as a transcription factor and plays a key role in defining the composition of the RNA polymerase II ... ERICH2 transcription produces three validated distinct mRNA variants. The longest transcript variant is 1,388 base pairs in ...
Tantin D.; Schild-Poulter C.; Wang V.; Hache R.J.; Sharp P.A. (December 1, 2005). "The Octamer Binding Transcription Factor Oct ... Lee K.B.; Sharp P.A. (December 7, 2004). "Transcription-dependent Polyubiquitination of RNA Polymerase II Requires Lysine 63 of ... and has discovered a class of miRNAs that are produced from sequences adjacent to transcription start sites. His laboratory ... 3 (3): 69-70. doi:10.1111/j.1752-8062.2010.00197.x. PMC 5350715. PMID 20590673. Sharp, P. A.; Sharp, P (2005). "Phillip Sharp ...
June 1998). "Recruitment of octamer transcription factors to DNA by glucocorticoid receptor". Molecular and Cellular Biology. ... "Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the ... The biological response depends on the cell type.[citation needed] In the absence of activated GR, other transcription factors ... However activated GR can complex with these other transcription factors and prevent them from binding their target genes and ...
"The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS". The Journal of Biological Chemistry. 273 ... Hallier M, Tavitian A, Moreau-Gachelin F (May 1996). "The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA ... Hallier M, Tavitian A, Moreau-Gachelin F (May 1996). "The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA ... protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription". Endocrinology. ...
"Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors". Nature. 569 (7754): 136-140. Bibcode ... "Nucleosome movement by CHRAC and ISWI without disruption or trans-displacement of the histone octamer". Cell. 97 (7): 843-852. ... activities of ISWI and SWI/SNF are distinct and mediate the binding of non-overlapping sets of DNA transcription factors. The ... nucleosome remodeling factor), CHRAC (chromatin remodeling and assembly complex) and ACF (ATP-utilising chromatin remodeling ...
Dantonel JC, Murthy KG, Manley JL, Tora L (1997). "Transcription factor TFIID recruits factor CPSF for formation of 3' end of ... Hoffmann A, Chiang CM, Oelgeschläger T, Xie X, Burley SK, Nakatani Y, Roeder RG (1996). "A histone octamer-like structure ... Transcription initiation factor TFIID subunit 12 is a protein that in humans is encoded by the TAF12 gene. Control of ... Overview of all the structural information available in the PDB for UniProt: Q16514 (Transcription initiation factor TFIID ...
Transcription factors Transcription factors with highest matrix scores that bind to sequences within the promoter (ID GXP_ ... CCCTC-binding factor) HDBP (Huntington's disease gene regulatory region) OCT1 (octamer binding protein) E2FF (E2F-myc activator ... C2H2 zinc finger transcription factor 7) EGRF (EGR/nerve growth factor induced protein) CDEF (cell cycle dependent element - ... 1499160) are shown below: STAT (signal transducer and activator of transcription) Muscle TATA box NOLF (neuron-specific ...