Loading...
*  Number needed to treat
The signs of the numbers needed to treat and the numbers needed to hurt are reversed: NNT is 3.33 and NNH is −10.) Number ... Hutton JL (2010). "Misleading Statistics: The Problems Surrounding Number Needed to Treat and Number Needed to Harm". Pharm Med ... The NNT is the average number of patients who need to be treated to prevent one additional bad outcome (e.g. the number of ... "Number Needed to Treat". Bandolier. Retrieved 2017-04-21. Nuovo, J.; Melnikow J.; Chang D. (2002-06-05). "Reporting number ...
*  Absolute risk reduction
Natural numbers, which are used in the number needed to treat approach, are easily understood by non-experts. Absolute measures ... It is the inverse of the number needed to treat. In general, absolute risk reduction is the difference between one treatment ... Number needed to harm "An overview of measurements in epidemiology" (PDF). Archived from the original (PDF) on 2011-07-23. ... The rate of colon cancer for a five-year treatment with the drug is therefore 1/6,000, as by treating 6,000 people with the ...
*  Relative risk reduction
... absolute risk reduction and number needed to treat". CMAJ. 171 (4): 353-8. doi:10.1503/cmaj.1021197. PMC 509050 . PMID 15313996 ... although the signs may need to be adjusted, depending upon how the data was collected.) Barratt A, Wyer P, Hatala R, McGinn T, ...
*  Light therapy
Newman TB, Kuzniewicz MW, Liljestrand P, Wi S, McCulloch C, Escobar GJ (May 2009). "Numbers needed to treat with phototherapy ... He developed the first artificial light source for this purpose.[citation needed] Finsen used short wavelength light to treat ... medical citation needed] Light therapy which strikes the retina of the eyes is used to treat diabetic retinopathy and also ... citation needed] skin treatments,[which?] and accelerated wound healing.[citation needed] Blood irradiation therapy Free- ...
*  Number needed to harm
Glossary of Terms Hutton JL (2010). "Misleading Statistics: The Problems Surrounding Number Needed to Treat and Number Needed ... NNH is similar to Number needed to treat (NNT), where NNT usually refers to a therapeutic intervention and NNH to a detrimental ... The number needed to harm (NNH) is an epidemiological measure that indicates how many patients on average need to be exposed to ... year In the context of the example the number needed to harm can be introduced as the estimate of the number of patients needed ...
*  David Sackett
The number needed to treat: a clinically useful measure of treatment effect. BMJ. 1995 February 18;310(6977):452-4. PMID ...
*  Effect Model law
The Number Needed to Treat (NNT) is often used to benchmark medicines. The drug with the lowest NNT is said to be more ... Cook, R. J.; Sackett, D. L. The number needed to treat: a clinically useful measure of treatment effect. BMJ British Medical ... Kassai, B.; Gueyffier, F.; Boissel, J. P.; Boutitie, F.; Cucherat, M. Absolute benefit, number needed to treat and gain in life ... Kristiansen, I. S.; Gyrd-Hansen, D. Cost-effectiveness analysis based on the number-needed-to-treat: common sense or non-sense ...
*  Human leg
A Numbers-Needed-to-Treat and Cost-Benefit Analysis". Journal of Athletic Training. 39 (1): 95-100. PMC 385268 . "Easing the ... There are a number of exercises that can be done to strengthen the lower leg. For example, in order to activate plantar flexors ... The lower leg and ankle need to keep exercised and moving well as they are the base of the whole body. The lower extremities ... To relieve heel pain, simple therapies may be all you need". Harvard Women's Health Watch. 14 (12): 4-5. 2007. PMID 17722355. ...
*  Postherpetic neuralgia
number needed to treat=11). Due to the need for topical anesthesia before application of the high-dose capsaicin patch, ... number needed to treat (NNT)=2). Low-dose capsaicin may be useful for reducing PHN-associated pain but is limited by side ... number needed to treat =3.3). A single topical application of a high-dose capsaicin patch over the affected area after numbing ... number needed to harm=16). The anticonvulsant medications pregabalin and gabapentin also effectively relieve postherpetic ...
*  Management of prostate cancer
4.9 patients must be treated for one to benefit (number needed to treat = 4.9). Other recent studies have shown RALP to result ... A 2012 UK trial of focal HIFU on 41 patients reported no histological evidence of cancer in 77% of men treated (95% confidence ... Radiation therapy exploits this fact to treat cancer. Two different kinds of radiation therapy are used in prostate cancer ... In advanced stages of prostate cancer, radiation is used to treat painful bone metastases or reduce spinal cord compression. ...
*  Cervical screening
3.8 patients must be treated for one to benefit (number needed to treat = 3.8). Click here to adjust these results for patients ... HPV testing appears as sensitive as immediate colposcopy while reducing the number of colposcopies needed. randomized ... There are a number of different types of screening method available. In the USA, cervical screening is usually performed using ... This helps ensure that follow-up care can be provided on the spot and reduces the number of women who may miss out on treatment ...
*  Preotact
For patients who were already fractured, the number needed to treat (NNT) was 21. In the same study mentioned above, Preotact ... To prevent one or more new vertebral fractures, 48 women had to be treated for a median of 18 months for the total population. ... Following treatment with Preotact, patients can be treated with a bisphosphonate to further increase bone mineral densisty ...
*  Number needed to vaccinate
Number needed to treat Kelly H, Attia J, Andrews R, Heller RF (June 2004). "The number needed to vaccinate (NNV) and population ... It is a specific application of the number needed to treat metric (NNT) that incorporates the implications of herd immunity. ... Number needed to vaccinate (NNV) is a metric used in the evaluation of vaccines, and in the determination of vaccination policy ... For example, one study reported a number needed to vaccinate of 5206 for invasive pneumococcal disease. In order to determine a ...
*  Evidence-based pharmacy in developing countries
Application of NNTs (numbers needed to treat) to the underpinning evidence should further strengthen the lists. At present, ... The model list is perceived by the WHO to be an indication of a common core of medicines to cover most common needs. There is a ... Often, poor patients need help from pharmacists to understand which are the most important medicines and to identify the items ... In addition, a number of guiding principles for essential drug programs have emerged. The initial essential drugs list should ...
*  Varicocele
... this has a number needed to treat of 7 for varicocelectomy and 17 for embolization. There are also studies showing that the ... A 2012 Cochrane review found tentative but unclear evidence of improved fertility among males treated for varicocele. Around 15 ...
*  Belimumab
Based on the number needed to treat, approximately eleven patients must be treated for one to benefit. It was not tested in ... A greater number of serious infections and deaths were reported in patients treated with belimumab than in those treated with ... Belimumab reduces the number of circulating B cells, but anti-CD20 monoclonal antibodies reduce the number even more. It is ... Benlysta was the first new drug to treat lupus after 56 years. Sales rose to $31.2 million in the first quarter of 2012. It is ...
*  Systolic Blood Pressure Intervention Trial
The number needed to treat with intensive therapy instead of standard therapy to prevent one death was 90. The results were so ... The study implies that patients receiving "standard" therapy were controlled similarly to all adults being treated for ... treating to a systolic blood pressure target of less than 120 mm Hg is superior to a target of 140 mm Hg. The primary outcome ... hypertension and that patients receiving "intensive" therapy had a lower mean SBP compared to all adults being treated for ...
*  Clonazepam
2006). "Comparison of various treatments for sleep bruxism using determinants of number needed to treat and effect size". Int J ... citation needed] Clonazepam is also effective in the management of acute mania. Restless legs syndrome can be treated using ... The study examined the number of times the non-medical use of certain drugs was implicated in an ED visit. The criteria for non ... Many individuals treated on a long-term basis develop a dependence. Physiological dependence was demonstrated by flumazenil- ...
*  Population Impact Measures
Note: Number Needed to Treat (NNT): 1/(Baseline risk x Relative Risk Reduction)] The formula is: PIN-ER-t = N*Ip*PAR Where: N ... called the Number needed to treat. Population Impact Measures are an extension of these statistics, as they are measures of ... NEPP extends the well-known measure Number needed to treat (NNT) beyond the individual patient to the population. To describe ... Heller, R. F; Dobson, AJ (2000). "Disease impact number and population impact number: population perspectives to measures of ...
*  Experimental event rate
... relative risk reduction and number needed to treat. The control event rate (CER) is identical to the experimental event rate ... Absolute risk reduction Relative risk reduction Number needed to treat http://www.medicine.ox.ac.uk/bandolier/booth/glossary/ ... in comparison to patients in placebo or traditionally treated control groups. Three statistical terms rely on EER for their ...
*  Palmitoylethanolamide
In a 2015 analysis of a double blind placebo controlled study of PEA in sciatic pain, the Numbers Needed to Treat was 1.5. Its ... Since 2012 a number of new trials have been published, among which studies in glaucoma. PEA also seems to be one of the factors ... Chronic pain and neuropathic pain are indications for which there is high unmet need in the clinic. PEA has been tested in a ... Pain decrease after two weeks of treatment was significantly higher in PEA treated patients than in patients receiving the ...
*  Percentage point
... also known as the number needed to treat (NNT). In this case, the reciprocal transform of the percentage-point difference would ... be 1/(20%) = 1/0.20 = 5. Thus if 5 patients are treated with the drug, one could expect to heal one more case of the disease ...
*  Selegiline
... number needed to treat, number needed to harm, and likelihood to be helped or harmed". J Affect Disord. 151 (2): 409-17. doi: ... the number needed to treat (a sign of effect size, so a low number is better) for the patch for symptom reduction was 11, and ... The number needed to harm (inverse of the NNT, a high number here is better) ranged from 387 for sexual side effects to 7 for ... In its pill form, selegiline is used to treat symptoms of Parkinson's disease. It can be used on its own or in a combination ...
*  Management of atrial fibrillation
... a randomized controlled trial found benefit in treating patients 75 years or over against aspirin with a number needed to treat ... Ablation (AF ablation) is a method that increasingly is used to treat cases of recurrent AF that are unresponsive to ... Recently, other approaches have been developed that promise to decrease or eliminate the need for antiarrhythmic agents. The ... Warfarin treatment requires frequent (usually monthly) monitoring with a blood test resulting in a standardized number known as ...
*  Health in North Korea
Soil-transmitted helminthiases: estimates of the number of children needing preventive chemotherapy and number treated, 2009. ... The number of doctors remains high, though there is a shortage of nurses, meaning that doctors often have to perform routine ... Beginning in the 1950s, the DPRK put great emphasis on healthcare, and between 1955 and 1986, the number of hospitals grew from ... These food shortages cause a number of malnutrition diseases. For example, a 2009 UNICEF report found that North Korea was "one ...
*  Anton Chekhov
It is not only the immense number of stories he wrote-for few, if any, writers have ever done more-it is the awesome frequency ... we need a very daring and alert sense of literature to make us hear the tune, and in particular those last notes which complete ... which he considered his principal profession though he made little money from it and treated the poor free of charge. In 1884 ...