Loading...
*  HIST1H1B
... called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of ... Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules ...
*  Nucleosome
MBInfo - What are nucleosomes Nucleosomes on the Richmond Lab website Proteopedia Nucleosomes Nucleosome at the PDB Dynamic ... cerevisae Well-positioned nucleosomes form boundaries of NFR. These nucleosomes are called +1-nucleosome and -1-nucleosome and ... which also assists with nucleosome sliding. The nucleosomes are also spaced by ATP-dependent nucleosome-remodeling complexes ... 1-nucleosome and several downstream nucleosomes also tend to incorporate H2A.Z histone variant Eukaryotic genomes are ...
*  Nucleosome remodeling factor
NURF catalyzes nucleosome sliding in either direction on DNA without any apparent modifications to the histone octamer itself. ... Nucleosome Remodeling Factor (NURF) is an ATP-dependent chromatin remodeling complex first discovered in Drosophila ... "Purification and properties of an ATP-dependent nucleosome remodeling factor". Cell. 83 (6): 1011-1020. doi:10.1016/0092-8674( ... Alkhatib, Suehyb G.; Landry, Joseph W. (2011-10-20). "The Nucleosome Remodeling Factor". FEBS Letters. 585 (20): 3197-3207. doi ...
*  Nucleosome Repeat Length
... (NRL) is the average distance between the centers of neighboring nucleosomes. NRL is an important ... as well as long-range interactions between nucleosomes. NRL determines geometric properties of the nucleosome array, and ... or locally for a large enough genomic region containing several nucleosomes. In chromatin neighboring nucleosomes are separated ... Since the size of the nucleosome is typically fixed (146-147 base pairs), NRL is mostly determined by the size of the linker ...
*  Nucleosome positioning region database
... (NPRD),is a database of nucleosome formation sites (NFSs). nucleosome Levitsky, Victor G ... Katokhin Aleksey V; Podkolodnaya Olga A; Furman Dagmara P; Kolchanov Nikolay A (Jan 2005). "NPRD: Nucleosome Positioning Region ...
*  Chromosome
... such a complex is called nucleosome and resembles a bead on a string. These nucleosomes pack tighter, during condensation ... Chromatin fiber is made of nucleosomes (histone octamers with part of a DNA strand attached to and wrapped around it). ... Pereira SL; Grayling RA; Lurz R; Reeve JN (1997). "Archaeal nucleosomes". Proc. Natl. Acad. Sci. U.S.A. 94 (23): 12633-7. ... Sandman K; Pereira SL; Reeve JN (1998). "Diversity of prokaryotic chromosomal proteins and the origin of the nucleosome". Cell ...
*  Nucleic acid double helix
The more recent solution of the single crystal X-ray structure of the nucleosome core particle showed nearly 150 base pairs of ... Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ (1997). "Crystal structure of the nucleosome core particle at 2.8 A ... This effect is particularly seen in DNA-protein binding where tight DNA bending is induced, such as in nucleosome particles. ... Crick FH (1976). "Linking numbers and nucleosomes". Proc Natl Acad Sci USA. 73 (8): 2639-43. Bibcode:1976PNAS...73.2639C. doi: ...
*  Protein quaternary structure
Examples include nucleosomes and microtubules. Changes in quaternary structure can occur through conformational changes within ...
*  Epigenetics
Eukaryotic genomes have numerous nucleosomes. Nucleosome position is not random, and determine the accessibility of DNA to ... Thus nucleosome positioning is to some degree inheritable. Recent studies have uncovered connections between nucleosome ... directs recruitment and activation of the chromatin remodeling protein ALC1 that can cause nucleosome remodeling. Nucleosome ... It has been shown that at least some nucleosomes are retained in sperm cells (where most but not all histones are replaced by ...
*  William C. Earnshaw
Earnshaw, W. C.; Honda, B. M.; Laskey, R. A.; Thomas, J. O. (1980). "Assembly of nucleosomes: The reaction involving X. Laevis ... Laskey, R. A.; Earnshaw, W. C. (1980). "Nucleosome assembly". Nature. 286 (5775): 763-7. doi:10.1038/286763a0. PMID 6250082. ...
*  Histone octamer
The nucleosome core particle is the most basic form of DNA compaction in eukaryotes. Nucleosomes consist of a histone octamer ... Then two H2A-H2B dimers are connected to the DNA- H32-H42 complex to form a nucleosome. Each of the four core histones, in ... A histone octamer is the eight protein complex found at the center of a nucleosome core particle. It consists of two copies of ... As mentioned above the histone tails have been shown to directly interact with the DNA of the nucleosome. Each histone in the ...
*  SMARCA4
Peterson CL (April 2002). "Chromatin remodeling: nucleosomes bulging at the seams". Current Biology. 12 (7): R245-7. doi: ...
*  Chromosome conformation capture
In 1975, Chambon coined the term nucleosomes. In 1982, Chromosome territories were discovered. In 1984, John T. Lis innovated ... Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome. Nature, 446, 572. ...
*  DNA
Ito T (2003). "Nucleosome assembly and remodeling". Current Topics in Microbiology and Immunology. Current Topics in ... The histones form a disk-shaped complex called a nucleosome, which contains two complete turns of double-stranded DNA wrapped ... These proteins are important in bending arrays of nucleosomes and arranging them into the larger structures that make up ... Luger K, Mäder AW, Richmond RK, Sargent DF, Richmond TJ (September 1997). "Crystal structure of the nucleosome core particle at ...
*  Edward Trifonov
... within nucleosomes. It is known that in free DNA (i.e. DNA which is not part of a nucleosome), the DNA helix twists 360° per ... In a nucleosome, the DNA winds around the histone protein component. The principle of this winding (and thus the rules ... These two features of DNA present in the nucleosomes - curvature and bending have been now considered major factors playing a ... Comment on 'Cracking the chromatin code: Precise rule of nucleosome positioning' by Trifonov". Physics of Life Reviews. 8 (1): ...
*  DNA-binding protein
Ito T (2003). "Nucleosome assembly and remodelling". Curr Top Microbiol Immunol. 274: 1-22. doi:10.1007/978-3-642-55747-7_1. ... Luger K, Mäder A, Richmond R, Sargent D, Richmond T (1997). "Crystal structure of the nucleosome core particle at 2.8 A ... The histones form a disk-shaped complex called a nucleosome, which contains two complete turns of double-stranded DNA wrapped ... Sandman K, Pereira S, Reeve J (1998). "Diversity of prokaryotic chromosomal proteins and the origin of the nucleosome". Cell ...
*  FACT (biology)
The two subunits together, but neither alone, can stimulate formation of nucleosomes from free histones and DNA (histone ... Reinberg, D., Sims, R. (2006). de FACTo nucleosome dynamics. Journal of Biological Chemistry, 281(33) 23297-23391.. ... Nucleosome core particle) or Pol II. Co-immunoprecipitation assays with tagged recombinant proteins showed that the Spt16 ... a Factor that Facilitates Transcript Elongation through Nucleosomes". Cell. 92 (1): 105-116. doi:10.1016/S0092-8674(00)80903-4 ...
*  SWI/SNF
... mechanism and it involves the dissociation of DNA at the edge of the nucleosome with reassociation of DNA inside the nucleosome ... is capable of altering the position of nucleosomes along DNA. Two mechanisms for nucleosome remodeling by SWI/SNF have been ... Liu X, Li M, Xia X, Li X, Chen Z (April 2017). "Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure". ... In particular, the cryo-EM structure of the ATPase Snf2 in complex with a nucleosome shows that nucleosomal DNA is locally ...
*  Histone H2A
Resistance to nucleosomes occurs in H2A.Z by binding to H1 factor. H2A.Z gene is an essential gene in yeast and it is denoted ... Recent studies also show that nucleosome assembly protein 1 is also used to transport of H2A into the nucleus so it can wrap ... Chromatin Nucleosome Youngson, Robert M. (2006). Collins dictionary of human biology. Glasgow [Scotland]: Collins. ISBN 0-00- ... Physically, there are small changes on the surface area of the nucleosome that make the histone differ from H2A. Recent ...
*  Eukaryotic DNA replication
The nucleosome octamer includes two copies of each histone H2A, H2B, H3, and H4. Due to the tight association of histone ... After the deposition of histones H3-H4, nucleosomes form by the association of histone H2A-H2B. This process is thought to ... Gasser R, Koller T, Sogo JM (May 1996). "The stability of nucleosomes at the replication fork". J. Mol. Biol. 258 (2): 224-39. ... Type II topoisomerases are also used to separate linear strands as they are intricately folded into a nucleosome within the ...
*  Variant surface glycoprotein
Active VSG expression sites are depleted of nucleosomes. The gene repertoires in T. brucei have diverged to become strain- ... Stanne TM, Rudenko G (January 2010). "Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes". ...
*  Histone
The following is a list of human histone proteins: The nucleosome core is formed of two H2A-H2B dimers and a H3-H4 tetramer, ... The linker histone H1 binds the nucleosome at the entry and exit sites of the DNA, thus locking the DNA into place and allowing ... Luger K, Mäder AW, Richmond RK, Sargent DF, Richmond TJ (Sep 1997). "Crystal structure of the nucleosome core particle at 2.8 A ... During the 1980s, Yahli Lorch and Roger Kornberg showed that a nucleosome on a core promoter prevents the initiation of ...
*  Anti-dsDNA antibodies
Mice that have T cells directed towards the nucleosome can elicit a response to other antigens such as dsDNA and histone via a ... Anti-dsDNA antibodies might also be created secondary to the production of antibodies to other proteins within the nucleosome. ... Mortensen ES, Fenton KA, Rekvig OP (February 2008). "Lupus nephritis: the central role of nucleosomes revealed". Am. J. Pathol ... Rekvig OP, Nossent JC (February 2003). "Anti-double-stranded DNA antibodies, nucleosomes, and systemic lupus erythematosus: a ...
*  Chromatin
The nucleosome core particle, together with histone H1, is known as a chromatosome. Nucleosomes, with about 20 to 60 base pairs ... Main articles: Nucleosome, Chromatosome and Histone The basic repeat element of chromatin is the nucleosome, interconnected by ... 1-2). . The nucleosomes bind DNA non-specifically, as required by their function in general DNA packaging. There are, however, ... This means nucleosomes can bind preferentially at one position approximately every 10 base pairs (the helical repeat of DNA)- ...
*  RNA polymerase II holoenzyme
See: chromatin, histone, and nucleosome RNA Pol II catalysis improving factors. Improve the Vmax or Km of RNA Pol II, so ... See: chromatin, histone, and nucleosome. These methods of control can be combined in a modular method, allowing very high ...