... is a member of the nuclear receptor family of transcription factors. LXR-β is encoded by the NR1H2 gene (nuclear receptor ... "Entrez Gene: NR1H2 nuclear receptor subfamily 1, group H, member 2". Song C, Hiipakka RA, Kokontis JM, Liao S (Jun 1995). " ... group H, member 2). The liver X receptors (LXRs) were originally identified as orphan members of the nuclear receptor ... a new member of the gene family encoding the human steroid hormone nuclear receptor". Gene. 147 (2): 273-6. doi:10.1016/0378- ...
... also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I, member 2 ( ... group I, member 2) gene. PXR is a nuclear receptor whose primary function is to sense the presence of foreign toxic substances ... "Entrez Gene: NR1I2 nuclear receptor subfamily 1, group I, member 2". Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJ, Moen ... PXR belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding ...
TR2 is a member of the nuclear receptor family of transcription factors. Testicular receptor 2 has been shown to interact with ... "Entrez Gene: NR2C1 nuclear receptor subfamily 2, group C, member 1". Chang C, Kokontis J, Acakpo-Satchivi L, Liao S, Takeda H, ... group C, member 1) is protein that in humans is encoded by the NR2C1 gene. ... Lee CH, Chinpaisal C, Wei LN (Sep 1998). "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 ...
This protein is a member of nuclear hormone receptor family of steroid hormone receptors. Coup (chicken ovalbumin upstream ... "Entrez Gene: NR2F1 nuclear receptor subfamily 2, group F, member 1". Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson ... group F, member 1) is a protein that in humans is encoded by the NR2F1 gene. ... a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily". ...
"Entrez Gene: NR2F2 nuclear receptor subfamily 2, group F, member 2". Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson ... group F, member 2) is a protein that in humans is encoded by the NR2F2 gene. The COUP acronym stands for chicken ovalbumin ... September 2008). "Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor". PLOS Biology. 6 ( ... "The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II ...
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein ... group F, member 2) is a nuclear receptor that in humans is encoded by the RORB gene. ... RAR-related orphan receptor beta (ROR-beta), also known as NR1F2 (nuclear receptor subfamily 1, ... nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily". ...
... but it is closely related to other members of the nuclear receptor family and is functionally related to other nuclear receptor ... Rev-Erb beta (Rev-Erbβ), also known as nuclear receptor subfamily 1 group D member 2 (NR1D2), is a member of the Rev-Erb ... In mammals, the NR1D2 (nuclear receptor subfamily 1 group D member 2) gene encodes the protein Rev-Erbβ. Unlike NR1D1, the ... Enmark E, Kainu T, Pelto-Huikko M, Gustafsson JA (October 1994). "Identification of a novel member of the nuclear receptor ...
The nuclear receptor 4A2 (NR4A2) (nuclear receptor subfamily 4 group A member 2) also known as nuclear receptor related 1 ... "Entrez Gene: NR4A2 nuclear receptor subfamily 4, group A, member 2". Yi SH, He XB, Rhee YH, Park CH, Takizawa T, Nakashima K, ... NR4A2 is a member of the nuclear receptor family of intracellular transcription factors. NR4A2 plays a key role in the ... Nurr1+nuclear+receptor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ...
... nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene. LRH-1 is a member of ... Peng N, Kim JW, Rainey WE, Carr BR, Attia GR (Dec 2003). "The role of the orphan nuclear receptor, liver receptor homologue-1, ... Luo Y, Liang CP, Tall AR (Jul 2001). "The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human ... Nitta M, Ku S, Brown C, Okamoto AY, Shan B (Jun 1999). "CPF: an orphan nuclear receptor that regulates liver-specific ...
... (RAR-beta), also known as NR1B2 (nuclear receptor subfamily 1, group B, member 2) is a nuclear ... This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear ... Retinoic acid receptor beta has been shown to interact with NR4A2. Retinoic acid receptor GRCh38: Ensembl release 89: ... retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver ...
... (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear ... The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcription factors. ... Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of ... "The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms ...
Nuclear receptor TLX (homologue of the Drosophila tailless gene) also known as NR2E1 (Nuclear receptor subfamily 2 group E ... TLX is a member of the nuclear receptor family of intracellular transcription factors. TLX regulates the expression of another ... "Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX". Molecular and ... "Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX". Molecular and ...
... (TR-beta) also known as nuclear receptor subfamily 1, group A, member 2 (NR1A2), is a nuclear ... The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for ... Tagami T, Lutz WH, Kumar R, Jameson JL (December 1998). "The interaction of the vitamin D receptor with nuclear receptor ... Zhu XG, Park KS, Kaneshige M, Bhat MK, Zhu Q, Mariash CN, McPhie P, Cheng SY (April 2000). "The orphan nuclear receptor Ear-2 ...
The testicular receptor proteins are members of the nuclear receptor family of intracellular transcription factors. There are ... nuclear+receptor+subfamily+2,+group+C,+member+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) NR2C2+ ... "Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily". J. Steroid Biochem. Mol. Biol. 81 (4- ... Yoshikawa T, DuPont BR, Leach RJ, Detera-Wadleigh SD (1996). "New variants of the human and rat nuclear hormone receptor, TR4: ...
... (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear ... "The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms ... "Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors". ... dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4". ...
SMAD family member 7, nuclear receptor subfamily 4 group A member 1, and homeobox protein SIX3, and represses BCL11B as well as ... The novel sequence harbors a nuclear receptor binding motif LXXLL which confers MTA1 with an ability to interact with estrogen ... receptor alpha or other type I nuclear receptors. The ZG29p variant represents the c-terminal MTA1 with two proline-rich SH3 ... Kumar R, Gururaj AE (2008). "Coregulators as Oncogenes and Tumor Suppressors". In O'Malley BW, Kumar R (eds.). Nuclear Receptor ...
... nuclear receptor subfamily 4, group A, member 2 OLA1: Obg-like ATPase 1 PARD3B encoding protein Partitioning defective 3 ... subfamily A, members 5 and 8 ASXL2: Additional sex combs like 2, transcriptional regulator ATOH8: encoding protein Atonal bHLH ... Nuclear receptor-binding protein 1 ODC1: Ornithine decarboxylase OTOF: otoferlin PAIP2B: Poly(a) binding protein interacting ... subfamily A (ABC1), member 12 ACTR1B: encoding protein Beta-centractin AGXT: alanine-glyoxylate aminotransferase (oxalosis I; ...
... group I, member 3 is a protein that in humans is encoded by the NR1I3 gene. CAR is a member of the nuclear receptor superfamily ... The constitutive androstane receptor (CAR) also known as nuclear receptor subfamily 1, ... CAR is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. Unlike ... Baes M, Gulick T, Choi HS, Martinoli MG, Simha D, Moore DD (Mar 1994). "A new orphan member of the nuclear hormone receptor ...
... nuclear receptor subfamily 2 group F member 6) is a protein that in humans is encoded by the NR2F6 gene. V-erbA-related protein ... "Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related ... "Nuclear orphan receptors regulate transcription of the gene for the human luteinizing hormone receptor". The Journal of ... Zhu XG, Park KS, Kaneshige M, Bhat MK, Zhu Q, Mariash CN, McPhie P, Cheng SY (April 2000). "The orphan nuclear receptor Ear-2 ...
... group E, member 3), is a protein that in humans is encoded by the NR2E3 gene. PNR is a member of the nuclear receptor super ... The photoreceptor cell-specific nuclear receptor (PNR), also known as NR2E3 (nuclear receptor subfamily 2, ... January 2002). "The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration". ... January 2002). "The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration". ...
"Entrez Gene: NR0B2 nuclear receptor subfamily 0, group B, member 2". Lee HK, Lee YK, Park SH, Kim YS, Park SH, Lee JW, et al. ( ... The small heterodimer partner (SHP) also known as NR0B2 (nuclear receptor subfamily 0, group B, member 2) is a protein that in ... SHP is a member of the nuclear receptor family of intracellular transcription factors. SHP is unusual for a nuclear receptor in ... "The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms ...
In the NRNC classification scheme, Rev-Erb is nuclear receptor subfamily 1 group D (NR1D). The name "Rev-Erb" derived by ... The Rev-Erb proteins are members of the nuclear receptor (NR) superfamily of intracellular transcription factors and key ... "A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb". Molecular Endocrinology. 8 (8): ... Rev-Erbɑ Rev-Erbβ Nuclear Receptors Transcription Factors Circadian Clock Lazar MA, Jones KE, Chin WW (March 1990). "Isolation ...
... has been shown to activate expression of Nuclear receptor subfamily 5 group A member 1 (NR5A1). NR5A1 is involved in ... KIAA1257 is predicted to be localized to the nucleus and contains several nuclear localization signals. A summary of KIAA1257 ... Table 1 The protein KIAA1257 exists most commonly as a translation of the mRNA isoform X4, which is only half the length of ... Table 2 KIAA1257 is mainly expressed in the testes and ovaries of adult humans, however expression is low in these tissues. ...
... also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans ... MR is a receptor with equal affinity for mineralocorticoids and glucocorticoids. It belongs to the nuclear receptor family ... Sheppard KE (May 2002). "Nuclear receptors. II. Intestinal corticosteroid receptors". American Journal of Physiology. ... Thénot S, Henriquet C, Rochefort H, Cavaillès V (May 1997). "Differential interaction of nuclear receptors with the putative ...
... (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a ... nuclear receptor that in humans is encoded by the ESRRB (Estrogen Related Receptor Beta) gene . ESRRB has been shown to be ... March 1999). "Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR". Gene. 228 ... March 2005). "Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues". The ...
The nuclear receptor 4A1 (NR4A1 for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a ... The other two members are Nuclear receptor 4A2 (NR4A2) and Nuclear receptor 4A3 (NR4A3). Nuclear receptor 4A1 has a high degree ... "Entrez Gene: NR4A1 nuclear receptor subfamily 4, group A, member 1". Chang C, Kokontis J, Liao SS, Chang Y (1989). "Isolation ... Nuclear receptor 4A1 (NR4A1) is a member of the NR4A nuclear receptor family of intracellular transcription factors. NR4A1 is ...
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. In humans, 4 isoforms of RORα ... "The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease". Science ... RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear ... nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily". ...
... (RAR-α), also known as NR1B1 (nuclear receptor subfamily 1, group B, member 1) is a nuclear ... RARA codes for the nuclear hormone receptor retinoic acid receptor, alpha subtype, a transcription factor. There are another ... Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM (January 1992). "Retinoid X receptor interacts with nuclear receptors in ... "Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein". The ...
... member B FAM76B: Family with sequence similarity 76 member B FAR1: fatty acyl-coA reductase 1 FAT3: fat atypical cadherin 3 ... Apelin receptor (APJ receptor) APOA4: apolipoprotein A-IV ARCN1 encoding protein Archain 1 ART5: encoding protein Adp- ... U2 small nuclear 2 ROM1: retinal outer segment membrane protein 1 RPL27A: encoding protein 60S ribosomal protein L27a RPL36A: ... group I (pepsinogen A) PIWIL4 encoding protein Piwi like RNA-mediated gene silencing 4 PLET1: encoding protein Placenta ...
The PLC-δ subfamily consists of three family members, δ1, 2, and 3. PLC-δ1 (85kDa) is the most well understood of the three. ... PLC-γ (120-155kDa) is activated by receptor and non-receptor tyrosine kinases due to the presence of two SH2 and a single SH3 ... PLC-δ1 also possesses a classical leucine-rich nuclear export signal (NES) in its EF hand motif, as well as a Nuclear ... The first reaction is a phosphotransferase step that involves an intramolecular attack between the hydroxyl group at the 2' ...