Such structures are nuclear lamina, which consist of proteins termed lamins which can be also found in the nuclear matrix. For ... According to some sources, most, if not all proteins found in nuclear matrix are the aggregates of proteins of structures that ... The nuclear matrix proteome consists of structural proteins, chaperones, DNA/RNA-binding proteins, chromatin remodeling and ... "nuclear matrix" or "nuclear-scaffold" or "NuMat" is an essential component of the in vivo nuclear architecture has remained a ...
This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene ... 1992). "RFP is a DNA binding protein associated with the nuclear matrix". Nucleic Acids Res. 20 (20): 5305-10. doi:10.1093/nar/ ... 1998). "Ret finger protein is a normal component of PML nuclear bodies and interacts directly with PML". J. Cell Sci. 111 (10 ... Zinc finger protein RFP is a protein that in humans is encoded by the TRIM27 gene. This gene encodes a member of the tripartite ...
1990). "The nuclear matrix from cells of different origin. Evidence for a common set of matrix proteins". J. Biol. Chem. 265 ( ... 2003). "Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D ... The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with ... Belgrader P, Dey R, Berezney R (Jun 1991). "Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix ...
1999). "Reassembling proteins and chaperones in human nuclear matrix protein fractions". J. Cell. Biochem. 74 (2): 145-51. doi: ... 2000). "hNMP 200: a novel human common nuclear matrix protein combining structural and regulatory functions". Exp. Cell Res. ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ...
Proteins of the chromosome scaffold and nuclear matrix of eo-eukaryotes; Organization and function of the nucleus; Theoretical ...
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin ... 1989). "Association of Tat protein and viral mRNA with nuclear matrix from HIV-1-infected H9 cells". Biochim. Biophys. Acta. ... Ye Q, Worman HJ (1995). "Protein-protein interactions between human nuclear lamins expressed in yeast". Exp. Cell Res. 219 (1 ... During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are ...
Structural and Functional Organization of the Nuclear Matrix. International Review of Cytology. Vol. 162B. pp. 303-35. doi: ... The N-terminus of the protein contains a replication factory-targeting sequence that is used to recruit it to sites of DNA ... Leonhardt H, Cardoso MC (1996). "Targeting and association of proteins with functional domains in the nucleus: the insoluble ... of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins". The ...
This gene encodes a protein that localizes to the nuclear matrix. The protein also has RNA binding activity, and has a ... 2002). "The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA- ... MORC family CW-type zinc finger protein 3 is a protein that in humans is encoded by the MORC3 gene. ...
... is the abbreviated form of Nuclear Matrix Protein Number 22. It reflects the mitotic activity of cells. Kumar A, Kumar R ...
The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid ... "A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A". Biochem Biophys Res Commun. ... This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala- ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ...
... is involved in DNA-nuclear matrix anchoring". J. Cell. Biochem. 85 (4): 689-702. doi:10.1002/jcb.10169. PMID 11968009. S2CID ... proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER- ... Protein disulfide isomerase family A member 2 is a protein that in humans is encoded by the PDIA2 gene. This gene encodes a ... The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its ...
"Identification and characterization of the ubiquitously occurring nuclear matrix protein NMP 238". Biochem. Biophys. Res. ... Park J, Wood MA, Cole MD (2002). "BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134 ... "BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic ...
"A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A". Biochemical and Biophysical ... an RNA-helicase controlled by protein-protein interactions". Proceedings of the National Academy of Sciences of the United ... Together these three proteins are referred to as eIF4F. For maximal activity; eIF4A also requires eIF4B (80 kDa), which itself ... In addition these proteins are helicases that function to unwind double-stranded RNA. The mechanisms governing the basic ...
Zuber M, Heyden TS, Lajous-Petter AM (1995). "A human autoantibody recognizing nuclear matrix-associated nuclear protein ... That nuclear bodies co-isolated with the nuclear matrix, and were linked to the fibrogranular nuclear matrix component by ... NDP55 and 53kDa protein associated with the nuclear matrix. Other proteins, such as PIC1/SUMO-1, which are associated with ... A nuclear body subtype is a clastosome suggested to be a site of protein degradation. Simple nuclear bodies (types I and II) ...
Gotzmann J, Meissner M, Gerner C (May 2000). "The fate of the nuclear matrix-associated-region-binding protein SATB1 during ... of the Xlr nuclear protein in immature thymocytes and colocalization with the matrix-associated region-binding SATB1 protein". ... "A novel DNA-binding motif in the nuclear matrix attachment DNA-binding protein SATB1". Molecular and Cellular Biology. 14 (3): ... By binding to MARs and tethering these to the nuclear matrix, SATB1 creates chromatin loops. By changing the chromatin-loop ...
"Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB". Journal of Cellular ... Shav-Tal Y, Zipori D (Nov 2002). "PSF and p54(nrb)/NonO--multi-functional nuclear proteins". FEBS Letters. 531 (2): 109-14. doi ... "Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB". Journal of Cellular ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ...
Stauffer DR, Howard TL, Nyun T, Hollenberg SM (2002). "CHMP1 is a novel nuclear matrix protein affecting chromatin structure ... Charged multivesicular body protein 1b is a protein that in humans is encoded by the CHMP1B gene. GRCh38: Ensembl release 89: ... 2006). "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple ... "The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B". ...
"HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics". Journal of Cell Science. 113 Pt 21 ... "Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's ... cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95". Biology of the ... A-kinase anchor protein 8-like is a protein that in humans is encoded by the AKAP8L gene. AKAP8L has been shown to interact ...
"HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics". Journal of Cell Science. 113 Pt 21 ... "Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR". The Journal of ... "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to ... "Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to ...
"HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics". Journal of Cell Science. 113 Pt 21 ... "HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics". Journal of Cell Science. 113 Pt 21 ... LAP2 is an inner nuclear membrane (INM) protein. Thymopoietin is a protein involved in the induction of CD90 in the thymus. The ... "Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein". Molecular Biology of the Cell ...
Stauffer DR, Howard TL, Nyun T, Hollenberg SM (July 2001). "CHMP1 is a novel nuclear matrix protein affecting chromatin ... Charged multivesicular body protein 1a is a protein that in humans is encoded by the CHMP1A gene. This gene encodes a member of ... The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. ...
"HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics". J. Cell Sci. 113 (21): 3703-13. ... Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates ... Manilal S, Nguyen TM, Sewry CA, Morris GE (Jun 1996). "The Emery-Dreifuss muscular dystrophy protein, emerin, is a nuclear ... Emerin, together with LEMD3, is a LEM domain-containing integral protein of the inner nuclear membrane in vertebrates. Emerin ...
The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the ... has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix". J. ... Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a ... Spectrin, beta, non-erythrocytic 4, also known as SPTBN4, is a protein that in humans is encoded by the SPTBN4 gene. Spectrin ...
"The role of primer recognition proteins in DNA replication: association with nuclear matrix in HeLa cells". J. Cell Sci. 101 ... Click on genes, proteins and metabolites below to link to respective articles. [[File ... Jindal HK, Vishwanatha JK (1990). "Functional identity of a primer recognition protein as phosphoglycerate kinase". J. Biol. ... "Immunoelectron microscopic analysis of the intracellular distribution of primer recognition proteins, annexin 2 and ...
The nuclear lamina is similar in structure to the nuclear matrix, that extends throughout the nucleoplasm. The nuclear lamina ... The nuclear lamin-associated membrane proteins are either integral or peripheral membrane proteins. The most important are ... The nuclear lamina is associated with the inner face of the inner nuclear membrane of the nuclear envelope, whereas the outer ... proteins on the surface of the still partially condensed chromosomes, followed by nuclear envelope assembly. Novel nuclear pore ...
May 1998). "NRP/B, a novel nuclear matrix protein, associates with p110(RB) and is involved in neuronal differentiation". The ... Welch PJ, Wang JY (November 1993). "A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl ... The retinoblastoma protein (protein name abbreviated Rb; gene name abbreviated Rb, RB or RB1) is a tumor suppressor protein ... "The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers ...
Kim TA, Lim J, Ota S, Raja S, Rogers R, Rivnay B, Avraham H, Avraham S (May 1998). "NRP/B, a novel nuclear matrix protein, ... Seng S, Avraham HK, Jiang S, Yang S, Sekine M, Kimelman N, Li H, Avraham S (Sep 2007). "The nuclear matrix protein, NRP/B, ... chromosomal localization and regulation of expression of the neuronal nuclear matrix protein NRP/B in human brain tumors". Gene ... Ectoderm-neural cortex protein 1 is a protein that in humans is encoded by the ENC1 gene. DNA damage and/or hyperproliferative ...
Erdemir T, Bilican B, Oncel D, Goding CR, Yavuzer U (Jan 2002). "DNA damage-dependent interaction of the nuclear matrix protein ... Erdemir T, Bilican B, Oncel D, Goding CR, Yavuzer U (Jan 2002). "DNA damage-dependent interaction of the nuclear matrix protein ... The encoded protein contains bipartite nuclear targeting sequences that may provide nuclear transport for translin, which lacks ... Translin-associated protein X (abbr. TSNAX or TRAX) is a protein that in humans is encoded by the TSNAX gene. This gene encodes ...
1993). "A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells". Nature. 365 ( ... Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein ... Bukrinsky MI, Haffar OK (1998). "HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr". ... von Schwedler U, Kornbluth RS, Trono D (1994). "The nuclear localization signal of the matrix protein of human immunodeficiency ...
1993). "A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells". Nature. 365 ( ... takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear ... Bukrinsky MI, Haffar OK (1998). "HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr". ... von Schwedler U, Kornbluth RS, Trono D (1994). "The nuclear localization signal of the matrix protein of human immunodeficiency ...
This forms a ring-like structure that binds to the nuclear matrix, forming a PML-Nuclear body (PML-NB). The edge of the ring- ... PML protein is a tumor suppressor protein required for the assembly of a number of nuclear structures, called PML-nuclear ... including nuclear storage of proteins, serving as a dock where other proteins accumulate to be post-translationally modified, ... Nuclear receptor co-repressor 2, P53, RPL11, Retinoblastoma protein, Retinoic acid receptor alpha, SIN3A, SKI protein, STAT3, ...