Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of ... Wydner KL, McNeil JA, Lin F, Worman HJ, Lawrence JB (Feb 1997). "Chromosomal assignment of human nuclear envelope protein genes ... Lin F, Worman HJ (Nov 1995). "Structural organization of the human gene (LMNB1) encoding nuclear lamin B1". Genomics. 27 (2): ... Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins ...
"Nuclear accumulation of Saccharomyces cerevisiae Mcm3 is dependent on its nuclear localization sequence". Genes to Cells. 2 (10 ... Asf1 (and its partner Rtt109) has also been implicated in inhibiting gene expression from replicated genes during S-phase. The ... Hennessy KM, Lee A, Chen E, Botstein D (June 1991). "A group of interacting yeast DNA replication genes". Genes & Development. ... In S. cerevisiae, nuclear export is promoted by cyclin-dependent kinase (CDK) activity. Mcm proteins that are associated with ...
... that controls nuclear export and protein stability. The protein encoded by this gene belongs to the highly conserved cyclin ... The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the long arm of chromosome 11 (band 11q13). It ... "Entrez Gene: CCND1 cyclin D1". He Y, Liu Z, Qiao C, Xu M, Yu J, Li G (January 2014). "Expression and significance of Wnt ... "Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function". Proceedings ...
"Entrez Gene: XPO5 exportin 5". Yi R, Qin Y, Macara IG, Cullen BR (Dec 2003). "Exportin-5 mediates the nuclear export of pre- ... Exportin-5 (XPO5) is a protein that, in humans, is encoded by the XPO5 gene. In eukaryotic cells, the primary purpose of XPO5 ... Once in the cytoplasm, the microRNA (also known as miRNA) can act as a gene silencer by regulating translation of mRNA. ... Once the ternary complex is formed, it diffuses through a nuclear pore complex into the cytoplasm, transporting pre-miRNA into ...
Shen Y, Liu S, Fan J, Jin Y, Tian B, Zheng X, Fu H (April 2017). "Nuclear retention of the lncRNA SNHG1 by doxorubicin ... "Entrez Gene: Small nucleolar RNA host gene 1". Retrieved 2018-09-04. Tycowski, KT; Shu, MD; Steitz, JA (1 February 1996). "A ... Small nucleolar RNA host gene 1 is a non-protein coding RNA that in humans is encoded by the SNHG1 gene. This locus represents ... You J, Fang N, Gu J, Zhang Y, Li X, Zu L, Zhou Q (March 2014). "Noncoding RNA small nucleolar RNA host gene 1 promote cell ...
Mitchell J (2008). "Transcription factories are nuclear sub compartments that remain in the absence of transcription". Genes ... Gene translocation events occur when genes are in close proximity to one another; which will occur more often when a ... Transcription factories are also suggested to be responsible for gene clustering, this is because related genes would require ... Gene translocation events, like point mutations, generally are detrimental to the organism and so therefore could lead to the ...
Zhou S, Hayward SD (Sep 2001). "Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex". ... Corepressor interacting with RBPJ 1 is a protein that in humans is encoded by the CIR1 gene. CIR (gene) has been shown to ... "Entrez Gene: CIR CBF1 interacting corepressor". Zhou S, Fujimuro M, Hsieh JJ, Chen L, Hayward SD (Feb 2000). "A role for SKIP ... v t e (Articles with short description, Short description is different from Wikidata, Genes on human chromosome 2, All stub ...
TdT adds N-nucleotides to the V, D, and J exons of the TCR and BCR genes during antibody gene recombination, enabling the ... July 2001). "Terminal deoxynucleotidyltransferase directly interacts with a novel nuclear protein that is homologous to p65". ... In humans, terminal transferase is encoded by the DNTT gene. As a member of the X family of DNA polymerase enzymes, it works in ... Maezawa S, Hayano T, Koiwai K, Fukushima R, Kouda K, Kubota T, Koiwai O (May 2008). "Bood POZ containing gene type 2 is a human ...
During transcription in vivo, distal active genes are dynamically organized into shared nuclear subcompartments and colocalize ... processes for a group of genes useful under a specific conditions (for example, DNA repair genes or heat shock genes). ... An expressed gene is preferentially located outside of its chromosome territory, but a closely linked, inactive gene is located ... Estimates show that erythroid cells express at least 4,000 genes, so many genes are obliged to seek out and share the same ...
This protein is found in the 21st chromosome and is mostly located in nuclear speckles. Its higher expression is seen in ... "Entrez Gene: SON SON DNA binding protein". Ahn EY, DeKelver RC, Lo MC, Nguyen TA, Matsuura S, Boyapati A, Pandit S, Fu XD, ... SON protein is a protein that in humans is encoded by the SON gene. SON is the name that has been given to a large Ser/Arg (SR ... Mutation in SON gene is associated with ZTTK syndrome. The sequence length of the SON protein consists in 2426 aminoacids and ...
"Entrez Gene: NR2F2 nuclear receptor subfamily 2, group F, member 2". Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson ... Chu K, Zingg HH (1998). "The nuclear orphan receptors COUP-TFII and Ear-2 act as silencers of the human oxytocin gene promoter ... Jordan EM, Worley T, Breen GA (2003). "Transcriptional regulation of the nuclear gene encoding the alpha-subunit of the ... Human NR2F1 genome location and NR2F1 gene details page in the UCSC Genome Browser. Human NR2F2 genome location and NR2F2 gene ...
Franco PJ, Farooqui M, Seto E, Wei LN (August 2001). "The orphan nuclear receptor TR2 interacts directly with both class I and ... Petrie K, Guidez F, Howell L, Healy L, Waxman S, Greaves M, Zelent A (May 2003). "The histone deacetylase 9 gene encodes ... Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice. Histones are highly alkaline proteins ... Zhang J, Kalkum M, Chait BT, Roeder RG (March 2002). "The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK ...
They are nuclear RNAs which bind host proteins to form small nuclear ribonucleoproteins (snRNPs). The RNAs are 114-143 ... Genes Dev. 11 (19): 2557-2568. doi:10.1101/gad.11.19.2557. PMC 316563. PMID 9334320. Myer VE, Lee SI, Steitz JA (February 1992 ... The ever-growing world of small nuclear ribonucleoproteins. In The RNA world, 3rd edition (ed. R.F. Gesteland et al.), p. 327. ... Fan XC, Myer VE, Steitz JA (October 1997). "AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation ...
"A sequence motif conserved in diverse nuclear proteins identifies a protein interaction domain utilised for nuclear targeting ... "Entrez Gene: IWS1 IWS1 homolog (S. cerevisiae)". Krogan NJ, Kim M, Ahn SH, Zhong G, Kobor MS, Cagney G, Emili A, Shilatifard A ... Protein IWS1 homolog also known as interacts with Spt6 (IWS1) is a protein that in humans is encoded by the IWS1 gene. IWS1 is ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 2, All stub articles, ...
RNA-binding protein with serine-rich domain 1 is a protein that in humans is encoded by the RNPS1 gene. This gene encodes a ... Li C, Lin RI, Lai MC, Ouyang P, Tarn WY (Oct 2003). "Nuclear Pnn/DRS protein binds to spliced mRNPs and participates in mRNA ... Gene. 166 (2): 323-7. doi:10.1016/0378-1119(95)00571-4. PMID 8543184. "Entrez Gene: RNPS1 RNA binding protein S1, serine-rich ... Wilson KF, Fortes P, Singh US, Ohno M, Mattaj IW, Cerione RA (Feb 1999). "The nuclear cap-binding complex is a novel target of ...
May 2020). "The gene-rich genome of the scallop Pecten maximus". GigaScience. 9 (5). doi:10.1093/gigascience/giaa037. PMC ... Brand P, Saleh N, Pan H, Li C, Kapheim KM, Ramírez SR (September 2017). "The Nuclear and Mitochondrial Genomes of the ... horribilis". Genes. 9 (12): 598. doi:10.3390/genes9120598. PMC 6315469. PMID 30513700. Srivastava A, Kumar Sarsani V, Fiddes I ... July 2022). "De Novo Genome Assembly Highlights the Role of Lineage-Specific Gene Duplications in the Evolution of Venom in ...
"Chromosomal assembly of the nuclear genome of the endosymbiont-bearing trypanosomatid Angomonas deanei". G3: Genes, Genomes, ... Based on the 16S rRNA gene sequences, it is known that it originated from a common ancestor with the one in Strigomonas culicis ... Yet the paraflagellar rod gene PFR1 is fully functional. It also lacks introns and transcription of long polycistronic mRNAs ... The bacterium has highly reduced genome compared to its related bacterial species, lacking many genes essential for its ...
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are ... Romanelli MG, Lorenzi P, Morandi C (September 2000). "Organization of the human gene encoding heterogeneous nuclear ... Meissner M, Dechat T, Gerner C, Grimm R, Foisner R, Sauermann G (January 2000). "Differential nuclear localization and nuclear ... Meissner M, Dechat T, Gerner C, Grimm R, Foisner R, Sauermann G (January 2000). "Differential nuclear localization and nuclear ...
Stüven T, Hartmann E, Görlich D (November 2003). "Exportin 6: a novel nuclear export receptor that is specific for profilin. ... "Entrez Gene: ENAH enabled homolog (Drosophila)". Tani K, Sato S, Sukezane T, Kojima H, Hirose H, Hanafusa H, Shishido T (June ... Protein enabled homolog is a protein that in humans is encoded by the ENAH gene. ENAH has been shown to interact with ABI1, ZYX ... Sazuka T, Tomooka Y, Kathju S, Ikawa Y, Noda M, Kumar S (October 1992). "Identification of a developmentally regulated gene in ...
"A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction". Genes Dev. 14 (13): ... The EP300 gene is located on the long (q) arm of the human chromosome 22 at position 13.2. This gene encodes the adenovirus E1A ... "Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter". Diabetes. 51 (5): ... is encoded by the EP300 gene. It functions as histone acetyltransferase that regulates transcription of genes via chromatin ...
Smad nuclear-interacting protein 1 is a protein that in humans is encoded by the SNIP1 gene. SNIP1 has been shown to interact ... "Entrez Gene: SNIP1 Smad nuclear interacting protein 1". Kim RH, Flanders KC, Birkey Reffey S, Anderson LA, Duckett CS, Perkins ... "A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction". Genes Dev. 14 (13): ... Cui Q, Lim SK, Zhao B, Hoffmann FM (2005). "Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide ...
... "dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila". Development. 120 (12): 3473-86 ... Drosophila melanogaster genes, All stub articles, Gene stubs). ... dachshund (dac) is a gene involved in the development of the ... Popov VM, Wu K, Zhou J, Powell MJ, Mardon G, Wang C, Pestell RG (January 2010). "The Dachshund gene in development and hormone- ... It is activated by the Distal-less (Dll) gene. Dachshund homologue (DACH1) regulates tumorigenesis in humans as a part of the ...
The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in ... "Entrez Gene: KIN KIN, antigenic determinant of recA protein homolog (mouse)". Biard DS, Saintigny Y, Maratrat M, et al. (1997 ... 2003). "Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell ... 2003). "Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication". Proc. Natl. ...
Deed RW, Armitage S, Norton JD (1996). "Nuclear localization and regulation of Id protein through an E protein-mediated ... "Structural organisation and chromosomal mapping of the human Id-3 gene". Gene. 151 (1-2): 309-14. doi:10.1016/0378-1119(94) ... "Entrez Gene: ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein". Deed RW, Jasiok M, Norton JD (Apr ... DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene. Members of the ID family of helix- ...
"Antibodies to the 45 kDa DEK nuclear antigen in pauciarticular onset juvenile rheumatoid arthritis and iridocyclitis: selective ... The human DEK gene encodes the DEK protein. This gene encodes a protein with one SAP domain. The protein binds to cruciform DNA ... Gene. 343 (1): 1-9. doi:10.1016/j.gene.2004.08.029. PMID 15563827. Denisenko ON, O'Neill B, Ostrowski J, Van Seuningen I, ... Genes on human chromosome 6, All stub articles, Human chromosome 6 gene stubs, Oncogenes). ...
Cells do this by modulating the capping, splicing, addition of a Poly(A) Tail, the sequence-specific nuclear export rates, and ... Often, one gene regulator controls another, and so on, in a gene regulatory network. Gene regulation is essential for viruses, ... Gene structure Spatiotemporal gene expression "Can genes be turned on and off in cells?". Genetics Home Reference. Bell JT, Pai ... Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or ...
FTO partially co-localizes with nuclear speckles, which supports the notion that in the nucleus, m6A can be a substrate of FTO ... The obesity-associated noncoding region within the FTO gene interacts directly with the promoter of IRX3, a homeobox gene, and ... and the IRX3 and IRX5 genes. Recent studies revealed that carriers of common FTO gene polymorphisms show both a reduction in ... The FTO gene is widely expressed in both fetal and adult tissues. 38,759 Europeans were studied for variants of FTO obesity ...
Pan HW, Chou HY, Liu SH, Peng SY, Liu CL, Hsu HC (2007). "Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, ... Denticleless protein homolog is a protein that in humans is encoded by the DTL gene. DTL (gene) has been shown to interact with ... "Entrez Gene: DTL denticleless homolog (Drosophila)". Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A (Sep 2008). " ... Cheung WM, Chu AH, Chu PW, Ip NY (May 2001). "Cloning and expression of a novel nuclear matrix-associated protein that is ...
Transcriptional regulator ERG is a nuclear protein that binds purine-rich sequences of DNA. Transcriptional regulator ERG is ... "Gene Cards". Ohno T, Ouchida M, Lee L, Gatalica Z, Rao VN, Reddy ES (Oct 1994). "The EWS gene, involved in Ewing family of ... The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator. Genes in the ETS family ... Reddy ES, Rao VN, Papas TS (Sep 1987). "The erg gene: a human gene related to the ets oncogene". Proceedings of the National ...
"Nuclear and Mitochondrial Phylogenomics of the Sifakas Reveal Cryptic Variation in the Diademed Sifaka". Genes. 13 (6): 1026. ... is the product of the gene flow of Crowned Sifakas with its neighboring species. The crowned sifaka is found in the mangroves ...