"Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity". The ... Killer cell lectin-like receptor subfamily G member 1 is a protein that in humans is encoded by the KLRG1 gene. Natural killer ... an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells". European ... "Entrez Gene: KLRG1 killer cell lectin-like receptor subfamily G, member 1". Nakamura S, Kuroki K, Ohki I, Sasaki K, Kajikawa M ...
Killer cell lectin-like receptor subfamily B, member 1, also known as KLRB1, NKR-P1A or CD161 (cluster of differentiation 161 ... are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an ... "Entrez Gene: KLRB1 killer cell lectin-like receptor subfamily B, member 1". Smith FB, Connor JM, Lee AJ, Cooke A, Lowe GD, ... "IL-12-induced up-regulation of NKRP1A expression in human NK cells and consequent NKRP1A-mediated down-regulation of NK cell ...
Killer cell lectin-like receptor subfamily A (KLRA, alternative nomenclature Ly49) is a gene cluster coding proteins from ... which are membrane receptors expressed mainly on the surface of NK cells and other cells of immune system in some mammals ... "Klra MGI Mouse Complex/Cluster/Region Detail - MGI:96876 - killer cell lectin-like receptor, subfamily A". www.informatics.jax. ... Hao L, Klein J, Nei M (February 2006). "Heterogeneous but conserved natural killer receptor gene complexes in four major orders ...
"Entrez Gene: KLRC4 killer cell lectin-like receptor subfamily C, member 4". Vivier E, Tomasello E, Paul P (2002). "Lymphocyte ... 1999). "Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA". Science. 285 (5428): 727-9. doi: ... NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK ... Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without ...
"Entrez Gene: KLRC2 killer cell lectin-like receptor subfamily C, member 2". Lazetic S, Chang C, Houchins JP, Lanier LL, ... NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK ... Lanier LL, Corliss B, Wu J, Phillips JH (Jun 1998). "Association of DAP12 with activating CD94/NKG2C NK cell receptors". ... Hikami K, Tsuchiya N, Yabe T, Tokunaga K (Mar 2003). "Variations of human killer cell lectin-like receptors: common occurrence ...
CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D, member 1 (KLRD1) is a human ... "Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors". Immunity. ... "Entrez Gene: KLRD1 killer cell lectin-like receptor subfamily D, member 1". Lazetic S, Chang C, Houchins JP, Lanier LL, ... are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially ...
... is encoded by KLRK1 (killer cell lectin like receptor K1) gene which is located in the NK-gene complex (NKC) situated on ... In mice, proteins from orthologous RAET1/ULBP family fall into three subfamilies: Rae-1, H60, and MULT-1. ULBP2 is a stress- ... T cells, γδ T cells, activated CD8+ αβ T cells and activated macrophages. In humans, it is expressed by NK cells, γδ T cells ... NKG2G is a key stimulatory cell surface receptor. A low expression of the receptor is observed already in the early NK cells ...
It is used in cell-cell contacts, binding to sialylated glycans on target cells leading to inhibition of NK cell-dependent ... Varki A, Angata T (January 2006). "Siglecs--the major subfamily of I-type lectins". Glycobiology. 16 (1): 1R-27R. doi:10.1093/ ... Examples of negative signalling: CD22 is found on B cells. B cells become active when the B-cell receptor (BCR) binds to its ... Mammalian cells contain high levels of sialic acid and so when NK cells bind so called "self-cells", they are not activated and ...
NKT cells) γδ T cells Mucosal associated invariant T cells Innate lymphoid cells (ILC) Group 1 ILC Natural killer cells (NK ... Geijtenbeek TB, Gringhuis SI (July 2009). "Signalling through C-type lectin receptors: shaping immune responses". Nat. Rev. ... subfamily A LILRA1 LILRA2 LILRA3 LILRA4 LILRA5 LILRA6 LILR subfamily B LILRB1 LILRB2 LILRB3 LILRB4 LILRB5 Eicosanoid receptors ... Commonly termed CD4+ T cells Th1 cells Th2 cells Th3 cells Th17 cells TFH cells - Follicular helper T cells Cytotoxic T cells ...
IL2 is a lymphokine that induces the proliferation of responsive T cells. In addition, it acts on some B cells, via receptor- ... These factors, which include interleukin 2 (IL2), are secreted by lectin- or antigen-stimulated T cells, and have various ... IL-12 also has an important role in enhancing the cytotoxic function of NK cells and role in pathological Th1 responses, such ... Boulay JL, Paul WE (September 1993). "Hematopoietin sub-family classification based on size, gene organization and sequence ...